Standard : JIS Z7250 (Japan)
SAFETY DATA SHEET
Amplification Reagent
1. Product and company identification
Product name : Amplification Reagent
Used in : APTIMA CT Assay 301088, APTIMA CT Assay TIGRIS 250-test kit 301199,
APTIMA CT Assay TIGRIS 2x50-test kit 302224, APTIMA GC Assay 301091,
APTIMA GC Assay TIGRIS 250-test kit 301196, APTIMA GC Assay TIGRIS 2x50-
test kit 302225, APTIMA Combo 2 301032, APTIMA Combo 2 TIGRIS 250-test kit
301130, PROGENSA PCA3 Assay Kit CE 302355, PROGENSA PCA3 100-
Reaction Kit 302354, PROGENSA PSA 100-Reaction Kit 302357, PCA3 ASR
302247, PSA ASR 302250.
MSDS no. : 0025
Product type : Solid.
Supplier/Manufacturer : Gen-Probe Incorporated
10210 Genetic Center Drive
San Diego, CA 92121-4362
Emergency telephone : CHEMTREC International: (703) 527-3887
number (with hours of
operation)
Recommended use of the chemical
In vitro diagnostic.
Restrictions on use
Uses Industry category Use category Use sub- Function
category category
None identified.
2. Hazards identification
Classification of the : Not regulated.
substance or mixture
GHS label elements
Hazard statements : No known significant effects or critical hazards.
Precautionary statements
Prevention : Not applicable.
Response : Not applicable.
Storage : Not applicable.
Disposal : Not applicable.
Other hazards which do not : Not available.
result in classification
Country information
Japan - Classification : Not applicable.
3. Composition/information on ingredients
Substance/mixture : Mixture
Chemical name : Not applicable.
Other means of : Not applicable.
identification
CAS number/other identifiers
CAS number : Not applicable.
ENCS number : Not applicable.
ISHL number : Not applicable.
: 01/15/2008 Page: 1/6
Date of issue
Amplification Reagent
3. Composition/information on ingredients
Ingredient name % CAS number ENCS ISHL
None.
Due to differing non-hazardous components, the products listed in each part number in 鈥淯sed In鈥? section are
not interchangeable. See package insert for product use.
There are no ingredients present which, within the current knowledge of the supplier and in the concentrations
applicable, are classified as hazardous to health or the environment and hence require reporting in this
section.
Occupational exposure limits, if available, are listed in section 8.
4. First aid measures
First aid measures
Eye contact : Check for and remove any contact lenses. In case of contact with eyes, rinse
immediately with plenty of water. Get medical attention if symptoms occur.
Skin contact : Wash with soap and water. Get medical attention if symptoms occur.
Inhalation : If inhaled, remove to fresh air. If not breathing, give artificial respiration. Get medical
attention if symptoms appear.
Ingestion : Do not induce vomiting. Never give anything by mouth to an unconscious person.
Get medical attention if symptoms appear.
Protection of first-aiders : No action shall be taken involving any personal risk or without suitable training.
Notes to physician : In case of inhalation of decomposition products in a fire, symptoms may be delayed.
The exposed person may need to be kept under medical surveillance for 48 hours.
See section 11 for more detailed information on health effects and symptoms.
5. Fire-fighting measures
Extinguishing media
Suitable : Use an extinguishing agent suitable for the surrounding fire.
Not suitable : None known.
Hazardous thermal : Decomposition products may include the following materials:
carbon dioxide
decomposition products
carbon monoxide
nitrogen oxides
sulfur oxides
Special protective : Fire-fighters should wear appropriate protective equipment and self-contained
breathing apparatus (SCBA) with a full face-piece operated in positive pressure
equipment for fire-fighters
mode.
Remark : Not available.
6. Accidental release measures
Personal precautions, : No action shall be taken involving any personal risk or without suitable training.
Evacuate surrounding areas. Keep unnecessary and unprotected personnel from
protective equipment and
entering. Do not touch or walk through spilled material. Provide adequate
emergency procedures
ventilation. Wear appropriate respirator when ventilation is inadequate. Put on
appropriate personal protective equipment (see section 8).
Environmental precautions : Avoid dispersal of spilled material and runoff and contact with soil, waterways, drains
and sewers. Inform the relevant authorities if the product has caused environmental
pollution (sewers, waterways, soil or air).
Methods and materials for containment and cleaning up
Small spill : Move containers from spill area. Vacuum or sweep up material and place in a
designated, labeled waste container. Dispose of via a licensed waste disposal
contractor.
: 01/15/2008 Page: 2/6
Date of issue
Amplification Reagent
6. Accidental release measures
Large spill : Move containers from spill area. Approach release from upwind. Prevent entry into
sewers, water courses, basements or confined areas. Vacuum or sweep up material
and place in a designated, labeled waste container. Dispose of via a licensed waste
disposal contractor. Note: see section 1 for emergency contact information and
section 13 for waste disposal.
7. Handling and storage
Precautions for safe : Put on appropriate personal protective equipment (see section 8). Eating, drinking
and smoking should be prohibited in areas where this material is handled, stored and
handling
processed. Workers should wash hands and face before eating, drinking and
smoking. Do not ingest. Avoid contact with eyes, skin and clothing. Keep in the
original container or an approved alternative made from a compatible material, kept
tightly closed when not in use. Empty containers retain product residue and can be
hazardous. Do not reuse container.
Conditions for safe storage : Store in accordance with local regulations. Store in original container protected from
direct sunlight in a dry, cool and well-ventilated area, away from incompatible
materials (see section 10) and food and drink. Keep container tightly closed and
sealed until ready for use. Containers that have been opened must be carefully
resealed and kept upright to prevent leakage. Do not store in unlabeled containers.
Use appropriate containment to avoid environmental contamination.
8. Exposure controls/personal protection
Control parameters
Ingredient name Exposure limits
None.
Recommended monitoring : If this product contains ingredients with exposure limits, personal, workplace
atmosphere or biological monitoring may be required to determine the effectiveness
procedures
of the ventilation or other control measures and/or the necessity to use respiratory
protective equipment.
Appropriate engineering : No special ventilation requirements. Good general ventilation should be sufficient to
control worker exposure to airborne contaminants. If this product contains
controls
ingredients with exposure limits, use process enclosures, local exhaust ventilation or
other engineering controls to keep worker exposure below any recommended or
statutory limits.
Environmental exposure : Emissions from ventilation or work process equipment should be checked to ensure
they comply with the requirements of environmental protection legislation. In some
controls
cases, fume scrubbers, filters or engineering modifications to the process equipment
will be necessary to reduce emissions to acceptable levels.
Individual protection measures
Hygiene measures : Wash hands, forearms and face thoroughly after handling chemical products, before
eating, smoking and using the lavatory and at the end of the working period.
Appropriate techniques should be used to remove potentially contaminated clothing.
Wash contaminated clothing before reusing. Ensure that eyewash stations and
safety showers are close to the workstation location.
Respiratory protection : Use a properly fitted, air-purifying or supplied air respirator complying with an
approved standard if a risk assessment indicates this is necessary. Respirator
selection must be based on known or anticipated exposure levels, the hazards of the
product and the safe working limits of the selected respirator.
Hand protection : Chemical-resistant, impervious gloves complying with an approved standard should
be worn at all times when handling chemical products if a risk assessment indicates
this is necessary.
Eye protection : Safety eyewear complying with an approved standard should be used when a risk
assessment indicates this is necessary to avoid exposure to liquid splashes, mists,
gases or dusts.
: 01/15/2008 Page: 3/6
Date of issue
Amplification Reagent
8. Exposure controls/personal protection
Skin protection : Personal protective equipment for the body should be selected based on the task
being performed and the risks involved and should be approved by a specialist
before handling this product.
9. Physical and chemical properties
Appearance
Physical state : Solid.
Color : White to off-white.
pH : 7.7
Flammability (solid, gas) : Non-flammable in the presence of the following materials or conditions: open flames,
sparks and static discharge, heat, shocks and mechanical impacts, oxidizing
materials, reducing materials, combustible materials, organic materials, metals,
acids, alkalis and moisture.
10. Stability and reactivity
Chemical stability : The product is stable. Under normal conditions of storage and use, hazardous
polymerization will not occur.
Conditions to avoid : No specific data.
Incompatible materials : No specific data.
Hazardous decomposition : Under normal conditions of storage and use, hazardous decomposition products
products should not be produced.
11. Toxicological information
Most important health effects
Potential acute health effects
Inhalation : Exposure to decomposition products may cause a health hazard. Serious effects
may be delayed following exposure.
Ingestion : No known significant effects or critical hazards.
Skin contact : No known significant effects or critical hazards.
Eye contact : No known significant effects or critical hazards.
Potential chronic health effects
General : No known significant effects or critical hazards.
Inhalation : No known significant effects or critical hazards.
Ingestion : No known significant effects or critical hazards.
Skin contact : No known significant effects or critical hazards.
Eye contact : No known significant effects or critical hazards.
Carcinogenicity : No known significant effects or critical hazards.
Mutagenicity : No known significant effects or critical hazards.
Teratogenicity : No known significant effects or critical hazards.
Developmental effects : No known significant effects or critical hazards.
Fertility effects : No known significant effects or critical hazards.
Symptoms related to the physical, chemical and toxicological characteristics
Inhalation : No specific data.
Ingestion : No specific data.
: 01/15/2008 Page: 4/6
Date of issue
Amplification Reagent
11. Toxicological information
Skin : No specific data.
Eyes : No specific data.
Other information : Not available.
12. Ecological information
Environmental effects : No known significant effects or critical hazards.
Aquatic ecotoxicity
Product/ingredient name Test Species Exposure Result
Not available.
Product/ingredient name Aquatic half-life Photolysis Biodegradability
Not available.
Bioaccumulative potential
Product/ingredient name LogPow BCF Potential
Not available.
Mobility : Not available.
Other adverse effects : No known significant effects or critical hazards.
13. Disposal considerations
Disposal methods : The generation of waste should be avoided or minimized wherever possible. Empty
containers or liners may retain some product residues. This material and its
container must be disposed of in a safe way. Dispose of surplus and non-recyclable
products via a licensed waste disposal contractor. Disposal of this product, solutions
and any by-products should at all times comply with the requirements of
environmental protection and waste disposal legislation and any regional local
authority requirements. Avoid dispersal of spilled material and runoff and contact
with soil, waterways, drains and sewers.
14. Transport information
International transport regulations
IMDG / IATA : Not regulated by any transport mode.
15. Regulatory information
Japan Control Law : Not regulated.
Chemical Substances Control Law (CSCL)
Ingredient name Classification
Biodegradability : Not available.
Concentration of : Not available.
chemicals accumulated in
fish
Japan inventory (ENCS) : See Section 3.
Japan inventory (ISHL) : See Section 3.
Other regulations : Not available.
: 01/15/2008 Page: 5/6
Date of issue
Amplification Reagent
16. Other information
History
: 01/15/2008
Date of issue
Version :1
0
References : Not available.
Notice to reader
To the best of our knowledge, the information contained herein is accurate. However, neither the above
named supplier nor any of its subsidiaries assumes any liability whatsoever for the accuracy or completeness
of the information contained herein. Final determination of suitability of any material is the sole responsibility
of the user. All materials may present unknown hazards and should be used with caution. Although certain
hazards are described herein, we cannot guarantee that these are the only hazards that exist.
: 01/15/2008 Page: 6/6
Date of issue
Standard : JIS Z7250 (Japan)
SAFETY DATA SHEET
Amplification Reconstitution Solution
1. Product and company identification
Product name : Amplification Reconstitution Solution
Used in : APTIMA CT Assay 301088, APTIMA CT Assay TIGRIS 250-test kit 301199,
APTIMA CT Assay TIGRIS 2x50-test kit 302224, APTIMA GC Assay 301091,
APTIMA GC Assay TIGRIS 250-test kit 301196, APTIMA GC Assay TIGRIS 2x50-
test kit 302225, APTIMA Combo 2 301032, APTIMA Combo 2 TIGRIS 250-test kit
301130, PROGENSA PCA3 Assay Kit CE 302355, PROGENSA PCA3 100-
Reaction Kit 302354, PROGENSA PSA 100-Reaction Kit 302357,PCA3 ASR
302500; PSA ASR 302501.
MSDS no. : 0026
Product type : Liquid.
Supplier/Manufacturer : Gen-Probe Incorporated
10210 Genetic Center Drive
San Diego, CA 92121-4362
Emergency telephone : CHEMTREC International: (703) 527-3887
number (with hours of
operation)
Recommended use of the chemical
In vitro diagnostic.
Restrictions on use
Uses Industry category Use category Use sub- Function
category category
None identified.
2. Hazards identification
Classification of the : Not regulated.
substance or mixture
GHS label elements
Hazard statements : No known significant effects or critical hazards.
Precautionary statements
Prevention : Not applicable.
Response : Not applicable.
Storage : Not applicable.
Disposal : Not applicable.
Other hazards which do not : Not available.
result in classification
Country information
Japan - Classification : Not applicable.
3. Composition/information on ingredients
Substance/mixture : Mixture
Chemical name : Not applicable.
Other means of : Not applicable.
identification
CAS number/other identifiers
CAS number : Not applicable.
ENCS number : Not applicable.
ISHL number : Not applicable.
: 01/15/2008 Page: 1/6
Date of issue
Amplification Reconstitution Solution
3. Composition/information on ingredients
Ingredient name % CAS number ENCS ISHL
Magnesium chloride 1-5 7786-30-3 (1)-233 Not applicable.
Due to differing non-hazardous components, the products listed in each part number in 鈥淯sed In鈥? section are
not interchangeable. See package insert for product use.
There are no ingredients present which, within the current knowledge of the supplier and in the concentrations
applicable, are classified as hazardous to health or the environment and hence require reporting in this
section.
Occupational exposure limits, if available, are listed in section 8.
4. First aid measures
First aid measures
Eye contact : Check for and remove any contact lenses. In case of contact with eyes, rinse
immediately with plenty of water. Get medical attention if symptoms occur.
Skin contact : Wash with soap and water. Get medical attention if symptoms occur.
Inhalation : If inhaled, remove to fresh air. If not breathing, give artificial respiration. Get medical
attention if symptoms appear.
Ingestion : Do not induce vomiting. Never give anything by mouth to an unconscious person.
Get medical attention if symptoms appear.
Protection of first-aiders : No action shall be taken involving any personal risk or without suitable training.
Notes to physician : No specific treatment. Treat symptomatically. Contact poison treatment specialist
immediately if large quantities have been ingested or inhaled.
See section 11 for more detailed information on health effects and symptoms.
5. Fire-fighting measures
Extinguishing media
Suitable : Use an extinguishing agent suitable for the surrounding fire.
Not suitable : None known.
Hazardous thermal : Decomposition products may include the following materials:
halogenated compounds
decomposition products
metal oxide/oxides
Special protective : Fire-fighters should wear appropriate protective equipment and self-contained
breathing apparatus (SCBA) with a full face-piece operated in positive pressure
equipment for fire-fighters
mode.
Remark : Not available.
6. Accidental release measures
Personal precautions, : No action shall be taken involving any personal risk or without suitable training.
Evacuate surrounding areas. Keep unnecessary and unprotected personnel from
protective equipment and
entering. Do not touch or walk through spilled material. Avoid breathing vapor or
emergency procedures
mist. Provide adequate ventilation. Wear appropriate respirator when ventilation is
inadequate. Put on appropriate personal protective equipment (see section 8).
Environmental precautions : Avoid dispersal of spilled material and runoff and contact with soil, waterways, drains
and sewers. Inform the relevant authorities if the product has caused environmental
pollution (sewers, waterways, soil or air).
Methods and materials for containment and cleaning up
Small spill : Stop leak if without risk. Move containers from spill area. Dilute with water and mop
up if water-soluble or absorb with an inert dry material and place in an appropriate
waste disposal container. Dispose of via a licensed waste disposal contractor.
: 01/15/2008 Page: 2/6
Date of issue
Amplification Reconstitution Solution
6. Accidental release measures
Large spill : Stop leak if without risk. Move containers from spill area. Approach release from
upwind. Prevent entry into sewers, water courses, basements or confined areas.
Wash spillages into an effluent treatment plant or proceed as follows. Contain and
collect spillage with non-combustible, absorbent material e.g. sand, earth, vermiculite
or diatomaceous earth and place in container for disposal according to local
regulations (see section 13). Dispose of via a licensed waste disposal contractor.
Contaminated absorbent material may pose the same hazard as the spilled product.
Note: see section 1 for emergency contact information and section 13 for waste
disposal.
7. Handling and storage
Precautions for safe : Put on appropriate personal protective equipment (see section 8). Eating, drinking
and smoking should be prohibited in areas where this material is handled, stored and
handling
processed. Workers should wash hands and face before eating, drinking and
smoking. Do not ingest. Avoid contact with eyes, skin and clothing. Avoid breathing
vapor or mist. Keep in the original container or an approved alternative made from a
compatible material, kept tightly closed when not in use. Empty containers retain
product residue and can be hazardous. Do not reuse container.
Conditions for safe storage : Store in accordance with local regulations. Store in original container protected from
direct sunlight in a dry, cool and well-ventilated area, away from incompatible
materials (see section 10) and food and drink. Keep container tightly closed and
sealed until ready for use. Containers that have been opened must be carefully
resealed and kept upright to prevent leakage. Do not store in unlabeled containers.
Use appropriate containment to avoid environmental contamination.
8. Exposure controls/personal protection
Control parameters
Ingredient name Exposure limits
None.
Recommended monitoring : If this product contains ingredients with exposure limits, personal, workplace
atmosphere or biological monitoring may be required to determine the effectiveness
procedures
of the ventilation or other control measures and/or the necessity to use respiratory
protective equipment.
Appropriate engineering : No special ventilation requirements. Good general ventilation should be sufficient to
control worker exposure to airborne contaminants. If this product contains
controls
ingredients with exposure limits, use process enclosures, local exhaust ventilation or
other engineering controls to keep worker exposure below any recommended or
statutory limits.
Environmental exposure : Emissions from ventilation or work process equipment should be checked to ensure
they comply with the requirements of environmental protection legislation. In some
controls
cases, fume scrubbers, filters or engineering modifications to the process equipment
will be necessary to reduce emissions to acceptable levels.
Individual protection measures
Hygiene measures : Wash hands, forearms and face thoroughly after handling chemical products, before
eating, smoking and using the lavatory and at the end of the working period.
Appropriate techniques should be used to remove potentially contaminated clothing.
Wash contaminated clothing before reusing. Ensure that eyewash stations and
safety showers are close to the workstation location.
Respiratory protection : Use a properly fitted, air-purifying or supplied air respirator complying with an
approved standard if a risk assessment indicates this is necessary. Respirator
selection must be based on known or anticipated exposure levels, the hazards of the
product and the safe working limits of the selected respirator.
: 01/15/2008 Page: 3/6
Date of issue
Amplification Reconstitution Solution
8. Exposure controls/personal protection
Hand protection : Chemical-resistant, impervious gloves complying with an approved standard should
be worn at all times when handling chemical products if a risk assessment indicates
this is necessary.
Eye protection : Safety eyewear complying with an approved standard should be used when a risk
assessment indicates this is necessary to avoid exposure to liquid splashes, mists,
gases or dusts.
Skin protection : Personal protective equipment for the body should be selected based on the task
being performed and the risks involved and should be approved by a specialist
before handling this product.
9. Physical and chemical properties
Appearance
Physical state : Liquid.
Color : Yellow.
pH : Not available.
Flammability (solid, gas) : Non-flammable in the presence of the following materials or conditions: open flames,
sparks and static discharge, heat, shocks and mechanical impacts, oxidizing
materials, reducing materials, combustible materials, organic materials, metals,
acids, alkalis and moisture.
10. Stability and reactivity
Chemical stability : The product is stable. Under normal conditions of storage and use, hazardous
polymerization will not occur.
Conditions to avoid : No specific data.
Incompatible materials : No specific data.
Hazardous decomposition : Under normal conditions of storage and use, hazardous decomposition products
products should not be produced.
11. Toxicological information
Most important health effects
Potential acute health effects
Inhalation : No known significant effects or critical hazards.
Ingestion : No known significant effects or critical hazards.
Skin contact : No known significant effects or critical hazards.
Eye contact : No known significant effects or critical hazards.
Potential chronic health effects
General : No known significant effects or critical hazards.
Inhalation : No known significant effects or critical hazards.
Ingestion : No known significant effects or critical hazards.
Skin contact : No known significant effects or critical hazards.
Eye contact : No known significant effects or critical hazards.
Carcinogenicity : No known significant effects or critical hazards.
Mutagenicity : No known significant effects or critical hazards.
Teratogenicity : No known significant effects or critical hazards.
Developmental effects : No known significant effects or critical hazards.
: 01/15/2008 Page: 4/6
Date of issue
Amplification Reconstitution Solution
11. Toxicological information
Fertility effects : No known significant effects or critical hazards.
Symptoms related to the physical, chemical and toxicological characteristics
Inhalation : No specific data.
Ingestion : No specific data.
Skin : No specific data.
Eyes : No specific data.
Other information : Not available.
12. Ecological information
Environmental effects : No known significant effects or critical hazards.
Aquatic ecotoxicity
Product/ingredient name Test Species Exposure Result
magnesium chloride Mortality Fish 96 hours Acute LC50 2120 mg/L
Product/ingredient name Aquatic half-life Photolysis Biodegradability
Not available.
Bioaccumulative potential
Product/ingredient name LogPow BCF Potential
Not available.
Mobility : Not available.
Other adverse effects : No known significant effects or critical hazards.
13. Disposal considerations
Disposal methods : The generation of waste should be avoided or minimized wherever possible. Empty
containers or liners may retain some product residues. This material and its
container must be disposed of in a safe way. Dispose of surplus and non-recyclable
products via a licensed waste disposal contractor. Disposal of this product, solutions
and any by-products should at all times comply with the requirements of
environmental protection and waste disposal legislation and any regional local
authority requirements. Avoid dispersal of spilled material and runoff and contact
with soil, waterways, drains and sewers.
14. Transport information
International transport regulations
IMDG / IATA : Not regulated by any transport mode.
15. Regulatory information
Japan Control Law : Not regulated.
Chemical Substances Control Law (CSCL)
Ingredient name Classification
Biodegradability : Not available.
Concentration of : Not available.
chemicals accumulated in
fish
Japan inventory (ENCS) : See Section 3.
Japan inventory (ISHL) : See Section 3.
Other regulations : Not available.
: 01/15/2008 Page: 5/6
Date of issue
Amplification Reconstitution Solution
16. Other information
History
: 01/15/2008
Date of issue
Version :1
0
References : Not available.
Notice to reader
To the best of our knowledge, the information contained herein is accurate. However, neither the above
named supplier nor any of its subsidiaries assumes any liability whatsoever for the accuracy or completeness
of the information contained herein. Final determination of suitability of any material is the sole responsibility
of the user. All materials may present unknown hazards and should be used with caution. Although certain
hazards are described herein, we cannot guarantee that these are the only hazards that exist.
: 01/15/2008 Page: 6/6
Date of issue
Standard : JIS Z7250 (Japan)
SAFETY DATA SHEET
Probe Reagent
1. Product and company identification
Product name : Probe Reagent
Used in : APTIMA CT Assay 301088, APTIMA CT Assay TIGRIS 250-test kit 301199,
APTIMA CT Assay TIGRIS 2x50-test kit 302224, APTIMA GC Assay 301091,
APTIMA GC Assay TIGRIS 250-test kit 301196, APTIMA GC Assay TIGRIS 2x50-
test kit 302225, APTIMA Combo 2 301032, APTIMA Combo 2 TIGRIS 250-test kit
301130, PROGENSA PCA3 Assay Kit CE 302355, PROGENSA PCA3 100-
Reaction Kit 302354, PROGENSA PSA 100-Reaction Kit 302357, PCA3 ASR
302248, PSA ASR 302251.
MSDS no. : 0027
Product type : Solid.
Supplier/Manufacturer : Gen-Probe Incorporated
10210 Genetic Center Drive
San Diego, CA 92121-4362
Emergency telephone : CHEMTREC International: (703) 527-3887
number (with hours of
operation)
Recommended use of the chemical
In vitro diagnostic.
Restrictions on use
Uses Industry category Use category Use sub- Function
category category
None identified.
2. Hazards identification
Classification of the : Not regulated.
substance or mixture
GHS label elements
Hazard statements : No known significant effects or critical hazards.
Precautionary statements
Prevention : Not applicable.
Response : Not applicable.
Storage : Not applicable.
Disposal : Not applicable.
Other hazards which do not : Not available.
result in classification
Country information
Japan - Classification : Not applicable.
3. Composition/information on ingredients
Substance/mixture : Mixture
Chemical name : Not applicable.
Other means of : Not applicable.
identification
CAS number/other identifiers
CAS number : Not applicable.
ENCS number : Not applicable.
ISHL number : Not applicable.
: 01/15/2008 Page: 1/6
Date of issue
Probe Reagent
3. Composition/information on ingredients
Ingredient name % CAS number ENCS ISHL
Mercaptoethanesulfonic Acid, Sodium Salt 1-5 19767-45-4 2-(4)-808 Not applicable.
Due to differing non-hazardous components, the products listed in each part number in 鈥淯sed In鈥? section are
not interchangeable. See package insert for product use.
There are no ingredients present which, within the current knowledge of the supplier and in the concentrations
applicable, are classified as hazardous to health or the environment and hence require reporting in this
section.
Occupational exposure limits, if available, are listed in section 8.
4. First aid measures
First aid measures
Eye contact : Check for and remove any contact lenses. In case of contact with eyes, rinse
immediately with plenty of water. Get medical attention if symptoms occur.
Skin contact : Wash with soap and water. Get medical attention if symptoms occur.
Inhalation : If inhaled, remove to fresh air. If not breathing, give artificial respiration. Get medical
attention if symptoms appear.
Ingestion : Do not induce vomiting. Never give anything by mouth to an unconscious person.
Get medical attention if symptoms appear.
Protection of first-aiders : No action shall be taken involving any personal risk or without suitable training.
Notes to physician : In case of inhalation of decomposition products in a fire, symptoms may be delayed.
The exposed person may need to be kept under medical surveillance for 48 hours.
See section 11 for more detailed information on health effects and symptoms.
5. Fire-fighting measures
Extinguishing media
Suitable : Use an extinguishing agent suitable for the surrounding fire.
Not suitable : None known.
Hazardous thermal : Decomposition products may include the following materials:
carbon dioxide
decomposition products
carbon monoxide
nitrogen oxides
sulfur oxides
metal oxide/oxides
Special protective : Fire-fighters should wear appropriate protective equipment and self-contained
breathing apparatus (SCBA) with a full face-piece operated in positive pressure
equipment for fire-fighters
mode.
Remark : Not available.
6. Accidental release measures
Personal precautions, : No action shall be taken involving any personal risk or without suitable training.
Evacuate surrounding areas. Keep unnecessary and unprotected personnel from
protective equipment and
entering. Do not touch or walk through spilled material. Provide adequate
emergency procedures
ventilation. Wear appropriate respirator when ventilation is inadequate. Put on
appropriate personal protective equipment (see section 8).
Environmental precautions : Avoid dispersal of spilled material and runoff and contact with soil, waterways, drains
and sewers. Inform the relevant authorities if the product has caused environmental
pollution (sewers, waterways, soil or air).
Methods and materials for containment and cleaning up
: 01/15/2008 Page: 2/6
Date of issue
Probe Reagent
6. Accidental release measures
Small spill : Move containers from spill area. Vacuum or sweep up material and place in a
designated, labeled waste container. Dispose of via a licensed waste disposal
contractor.
Large spill : Move containers from spill area. Approach release from upwind. Prevent entry into
sewers, water courses, basements or confined areas. Vacuum or sweep up material
and place in a designated, labeled waste container. Dispose of via a licensed waste
disposal contractor. Note: see section 1 for emergency contact information and
section 13 for waste disposal.
7. Handling and storage
Precautions for safe : Put on appropriate personal protective equipment (see section 8). Eating, drinking
and smoking should be prohibited in areas where this material is handled, stored and
handling
processed. Workers should wash hands and face before eating, drinking and
smoking. Do not ingest. Avoid contact with eyes, skin and clothing. Keep in the
original container or an approved alternative made from a compatible material, kept
tightly closed when not in use. Empty containers retain product residue and can be
hazardous. Do not reuse container.
Conditions for safe storage : Store in accordance with local regulations. Store in original container protected from
direct sunlight in a dry, cool and well-ventilated area, away from incompatible
materials (see section 10) and food and drink. Keep container tightly closed and
sealed until ready for use. Containers that have been opened must be carefully
resealed and kept upright to prevent leakage. Do not store in unlabeled containers.
Use appropriate containment to avoid environmental contamination.
8. Exposure controls/personal protection
Control parameters
Ingredient name Exposure limits
None.
Recommended monitoring : If this product contains ingredients with exposure limits, personal, workplace
atmosphere or biological monitoring may be required to determine the effectiveness
procedures
of the ventilation or other control measures and/or the necessity to use respiratory
protective equipment.
Appropriate engineering : No special ventilation requirements. Good general ventilation should be sufficient to
control worker exposure to airborne contaminants. If this product contains
controls
ingredients with exposure limits, use process enclosures, local exhaust ventilation or
other engineering controls to keep worker exposure below any recommended or
statutory limits.
Environmental exposure : Emissions from ventilation or work process equipment should be checked to ensure
they comply with the requirements of environmental protection legislation. In some
controls
cases, fume scrubbers, filters or engineering modifications to the process equipment
will be necessary to reduce emissions to acceptable levels.
Individual protection measures
Hygiene measures : Wash hands, forearms and face thoroughly after handling chemical products, before
eating, smoking and using the lavatory and at the end of the working period.
Appropriate techniques should be used to remove potentially contaminated clothing.
Wash contaminated clothing before reusing. Ensure that eyewash stations and
safety showers are close to the workstation location.
Respiratory protection : Use a properly fitted, air-purifying or supplied air respirator complying with an
approved standard if a risk assessment indicates this is necessary. Respirator
selection must be based on known or anticipated exposure levels, the hazards of the
product and the safe working limits of the selected respirator.
Hand protection : Chemical-resistant, impervious gloves complying with an approved standard should
be worn at all times when handling chemical products if a risk assessment indicates
this is necessary.
: 01/15/2008 Page: 3/6
Date of issue
Probe Reagent
8. Exposure controls/personal protection
Eye protection : Safety eyewear complying with an approved standard should be used when a risk
assessment indicates this is necessary to avoid exposure to liquid splashes, mists,
gases or dusts.
Skin protection : Personal protective equipment for the body should be selected based on the task
being performed and the risks involved and should be approved by a specialist
before handling this product.
9. Physical and chemical properties
Appearance
Physical state : Solid. [Lyophilized.]
Color : White to off-white.
pH : 5
Flammability (solid, gas) : Not available.
10. Stability and reactivity
Chemical stability : The product is stable. Under normal conditions of storage and use, hazardous
polymerization will not occur.
Conditions to avoid : No specific data.
Incompatible materials : No specific data.
Hazardous decomposition : Under normal conditions of storage and use, hazardous decomposition products
products should not be produced.
11. Toxicological information
Most important health effects
Potential acute health effects
Inhalation : Exposure to decomposition products may cause a health hazard. Serious effects
may be delayed following exposure.
Ingestion : No known significant effects or critical hazards.
Skin contact : No known significant effects or critical hazards.
Eye contact : No known significant effects or critical hazards.
Potential chronic health effects
General : No known significant effects or critical hazards.
Inhalation : No known significant effects or critical hazards.
Ingestion : No known significant effects or critical hazards.
Skin contact : No known significant effects or critical hazards.
Eye contact : No known significant effects or critical hazards.
Carcinogenicity : No known significant effects or critical hazards.
Mutagenicity : No known significant effects or critical hazards.
Teratogenicity : No known significant effects or critical hazards.
Developmental effects : No known significant effects or critical hazards.
Fertility effects : No known significant effects or critical hazards.
Symptoms related to the physical, chemical and toxicological characteristics
Inhalation : No specific data.
Ingestion : No specific data.
: 01/15/2008 Page: 4/6
Date of issue
Probe Reagent
11. Toxicological information
Skin : No specific data.
Eyes : No specific data.
Other information : Not available.
12. Ecological information
Environmental effects : No known significant effects or critical hazards.
Aquatic ecotoxicity
Product/ingredient name Test Species Exposure Result
Not available.
Product/ingredient name Aquatic half-life Photolysis Biodegradability
Not available.
Bioaccumulative potential
Product/ingredient name LogPow BCF Potential
Not available.
Mobility : Not available.
Other adverse effects : No known significant effects or critical hazards.
13. Disposal considerations
Disposal methods : The generation of waste should be avoided or minimized wherever possible. Empty
containers or liners may retain some product residues. This material and its
container must be disposed of in a safe way. Dispose of surplus and non-recyclable
products via a licensed waste disposal contractor. Disposal of this product, solutions
and any by-products should at all times comply with the requirements of
environmental protection and waste disposal legislation and any regional local
authority requirements. Avoid dispersal of spilled material and runoff and contact
with soil, waterways, drains and sewers.
14. Transport information
International transport regulations
IMDG / IATA : Not regulated by any transport mode.
15. Regulatory information
Japan Control Law : Not regulated.
Chemical Substances Control Law (CSCL)
Ingredient name Classification
Biodegradability : Not available.
Concentration of : Not available.
chemicals accumulated in
fish
Japan inventory (ENCS) : See Section 3.
Japan inventory (ISHL) : See Section 3.
Other regulations : Not available.
: 01/15/2008 Page: 5/6
Date of issue
Probe Reagent
16. Other information
History
: 01/15/2008
Date of issue
Version :1
0
References : Not available.
Notice to reader
To the best of our knowledge, the information contained herein is accurate. However, neither the above
named supplier nor any of its subsidiaries assumes any liability whatsoever for the accuracy or completeness
of the information contained herein. Final determination of suitability of any material is the sole responsibility
of the user. All materials may present unknown hazards and should be used with caution. Although certain
hazards are described herein, we cannot guarantee that these are the only hazards that exist.
: 01/15/2008 Page: 6/6
Date of issue
Standard : JIS Z7250 (Japan)
SAFETY DATA SHEET
Probe Reconstitution Solution
1. Product and company identification
Product name : Probe Reconstitution Solution
Used in : APTIMA CT Assay 301088, APTIMA CT Assay TIGRIS 250-test kit 301199,
APTIMA CT Assay TIGRIS 2x50-test kit 302224, APTIMA GC Assay 301091,
APTIMA GC Assay TIGRIS 250-test kit 301196, APTIMA GC Assay TIGRIS 2x50-
test kit 302225, APTIMA Combo 2 301032, APTIMA Combo 2 TIGRIS 250-test kit
301130, PROGENSA PCA3 Assay Kit CE 302355, PROGENSA PCA3 100-
Reaction Kit 302354, PROGENSA PSA 100-Reaction Kit 302357, PCA3/PSA
Supplemental Fluids Kit 302030.
MSDS no. : 0028
Product type : Liquid.
Supplier/Manufacturer : Gen-Probe Incorporated
10210 Genetic Center Drive
San Diego, CA 92121-4362
Emergency telephone : CHEMTREC International: (703) 527-3887
number (with hours of
operation)
Recommended use of the chemical
In vitro diagnostic.
Restrictions on use
Uses Industry category Use category Use sub- Function
category category
None identified.
2. Hazards identification
Classification of the : SPECIFIC TARGET ORGAN TOXICITY (REPEATED EXPOSURE) blood system,
central nervous system (CNS), liver and reproductive organs - Category 2
substance or mixture
AQUATIC TOXICITY (ACUTE) - Category 3
GHS label elements
Signal word : Warning
Hazard statements : May cause damage to organs through prolonged or repeated exposure if swallowed.
(blood system, central nervous system (CNS), liver, reproductive organs)
Harmful to aquatic life.
Precautionary statements
Prevention : Avoid release to the environment. Do not breathe vapor.
Response : Get medical attention/advice if you feel unwell.
Storage : Not applicable.
Disposal : Dispose of contents and container in accordance with all local, regional, national and
international regulations.
Symbol :
Other hazards which do not : Not available.
result in classification
Country information
Japan - Classification : Other hazardous substances.
: 01/15/2008 Page: 1/6
Date of issue
Probe Reconstitution Solution
3. Composition/information on ingredients
Substance/mixture : Mixture
Chemical name : Not applicable.
Other means of : Not applicable.
identification
CAS number/other identifiers
CAS number : Not applicable.
ENCS number : Not applicable.
ISHL number : Not applicable.
Ingredient name % CAS number ENCS ISHL
Lithium chloride 1-5 7447-41-8 (1)-231 Not applicable.
Ethanol 1-5 64-17-5 (2)-202 Not applicable.
Succinic acid 1-5 110-15-6 (2)-846 Not applicable.
Hazardous materials listed are the same in each part number in " Used In " section, however due to differing
non-hazardous components, the use of these products are not interchangeable. See package insert for
product use.
There are no additional ingredients present which, within the current knowledge of the supplier and in the
concentrations applicable, are classified as hazardous to health or the environment and hence require
reporting in this section.
Occupational exposure limits, if available, are listed in section 8.
4. First aid measures
First aid measures
Eye contact : Check for and remove any contact lenses. In case of contact with eyes, rinse
immediately with plenty of water. Get medical attention if symptoms occur.
Skin contact : Wash with soap and water. Get medical attention if symptoms occur.
Inhalation : If inhaled, remove to fresh air. If not breathing, give artificial respiration. Get medical
attention if symptoms appear.
Ingestion : Do not induce vomiting. Never give anything by mouth to an unconscious person.
Get medical attention if symptoms appear.
Protection of first-aiders : No action shall be taken involving any personal risk or without suitable training. It
may be dangerous to the person providing aid to give mouth-to-mouth resuscitation.
Notes to physician : No specific treatment. Treat symptomatically. Contact poison treatment specialist
immediately if large quantities have been ingested or inhaled.
See section 11 for more detailed information on health effects and symptoms.
5. Fire-fighting measures
Extinguishing media
Suitable : Use an extinguishing agent suitable for the surrounding fire.
Not suitable : None known.
Hazardous thermal : Decomposition products may include the following materials:
carbon dioxide
decomposition products
carbon monoxide
sulfur oxides
halogenated compounds
metal oxide/oxides
Special protective : Fire-fighters should wear appropriate protective equipment and self-contained
breathing apparatus (SCBA) with a full face-piece operated in positive pressure
equipment for fire-fighters
mode.
Remark : Not available.
: 01/15/2008 Page: 2/6
Date of issue
Probe Reconstitution Solution
6. Accidental release measures
Personal precautions, : No action shall be taken involving any personal risk or without suitable training.
Evacuate surrounding areas. Keep unnecessary and unprotected personnel from
protective equipment and
entering. Do not touch or walk through spilled material. Do not breathe vapor or
emergency procedures
mist. Provide adequate ventilation. Wear appropriate respirator when ventilation is
inadequate. Put on appropriate personal protective equipment (see section 8).
Environmental precautions : Avoid dispersal of spilled material and runoff and contact with soil, waterways, drains
and sewers. Inform the relevant authorities if the product has caused environmental
pollution (sewers, waterways, soil or air). Water polluting material. May be harmful
to the environment if released in large quantities.
Methods and materials for containment and cleaning up
Small spill : Stop leak if without risk. Move containers from spill area. Dilute with water and mop
up if water-soluble or absorb with an inert dry material and place in an appropriate
waste disposal container. Dispose of via a licensed waste disposal contractor.
Large spill : Stop leak if without risk. Move containers from spill area. Approach release from
upwind. Prevent entry into sewers, water courses, basements or confined areas.
Wash spillages into an effluent treatment plant or proceed as follows. Contain and
collect spillage with non-combustible, absorbent material e.g. sand, earth, vermiculite
or diatomaceous earth and place in container for disposal according to local
regulations (see section 13). Dispose of via a licensed waste disposal contractor.
Contaminated absorbent material may pose the same hazard as the spilled product.
Note: see section 1 for emergency contact information and section 13 for waste
disposal.
7. Handling and storage
Precautions for safe : Put on appropriate personal protective equipment (see section 8). Eating, drinking
and smoking should be prohibited in areas where this material is handled, stored and
handling
processed. Workers should wash hands and face before eating, drinking and
smoking. Do not breathe vapor or mist. Do not ingest. Avoid contact with eyes, skin
and clothing. Avoid release to the environment. Keep in the original container or an
approved alternative made from a compatible material, kept tightly closed when not
in use. Empty containers retain product residue and can be hazardous. Do not
reuse container.
Conditions for safe storage : Store in accordance with local regulations. Store in original container protected from
direct sunlight in a dry, cool and well-ventilated area, away from incompatible
materials (see section 10) and food and drink. Keep container tightly closed and
sealed until ready for use. Containers that have been opened must be carefully
resealed and kept upright to prevent leakage. Do not store in unlabeled containers.
Use appropriate containment to avoid environmental contamination.
8. Exposure controls/personal protection
Control parameters
Ingredient name Exposure limits
None.
Recommended monitoring : If this product contains ingredients with exposure limits, personal, workplace
atmosphere or biological monitoring may be required to determine the effectiveness
procedures
of the ventilation or other control measures and/or the necessity to use respiratory
protective equipment.
Appropriate engineering : If user operations generate dust, fumes, gas, vapor or mist, use process enclosures,
local exhaust ventilation or other engineering controls to keep worker exposure to
controls
airborne contaminants below any recommended or statutory limits.
Environmental exposure : Emissions from ventilation or work process equipment should be checked to ensure
they comply with the requirements of environmental protection legislation. In some
controls
cases, fume scrubbers, filters or engineering modifications to the process equipment
will be necessary to reduce emissions to acceptable levels.
: 01/15/2008 Page: 3/6
Date of issue
Probe Reconstitution Solution
8. Exposure controls/personal protection
Individual protection measures
Hygiene measures : Wash hands, forearms and face thoroughly after handling chemical products, before
eating, smoking and using the lavatory and at the end of the working period.
Appropriate techniques should be used to remove potentially contaminated clothing.
Wash contaminated clothing before reusing. Ensure that eyewash stations and
safety showers are close to the workstation location.
Respiratory protection : Use a properly fitted, air-purifying or supplied air respirator complying with an
approved standard if a risk assessment indicates this is necessary. Respirator
selection must be based on known or anticipated exposure levels, the hazards of the
product and the safe working limits of the selected respirator.
Hand protection : Chemical-resistant, impervious gloves complying with an approved standard should
be worn at all times when handling chemical products if a risk assessment indicates
this is necessary.
Eye protection : Safety eyewear complying with an approved standard should be used when a risk
assessment indicates this is necessary to avoid exposure to liquid splashes, mists,
gases or dusts.
Skin protection : Personal protective equipment for the body should be selected based on the task
being performed and the risks involved and should be approved by a specialist
before handling this product.
9. Physical and chemical properties
Appearance
Physical state : Liquid.
Color : Colorless to light yellow.
pH : 4.7
Flammability (solid, gas) : Not available.
10. Stability and reactivity
Chemical stability : The product is stable. Under normal conditions of storage and use, hazardous
polymerization will not occur.
Conditions to avoid : Avoid release to the environment.
Incompatible materials : No specific data.
Hazardous decomposition : Under normal conditions of storage and use, hazardous decomposition products
products should not be produced.
11. Toxicological information
Most important health effects
Potential acute health effects
Inhalation : No known significant effects or critical hazards.
Ingestion : No known significant effects or critical hazards.
Skin contact : No known significant effects or critical hazards.
Eye contact : No known significant effects or critical hazards.
Potential chronic health effects
General : May cause damage to organs through prolonged or repeated exposure.
Inhalation : No known significant effects or critical hazards.
: 01/15/2008 Page: 4/6
Date of issue
Probe Reconstitution Solution
11. Toxicological information
Ingestion : May cause damage to organs through prolonged or repeated exposure if swallowed.
Skin contact : No known significant effects or critical hazards.
Eye contact : No known significant effects or critical hazards.
Carcinogenicity : No known significant effects or critical hazards.
Mutagenicity : No known significant effects or critical hazards.
Teratogenicity : No known significant effects or critical hazards.
Developmental effects : No known significant effects or critical hazards.
Fertility effects : No known significant effects or critical hazards.
Symptoms related to the physical, chemical and toxicological characteristics
Inhalation : No specific data.
Ingestion : No specific data.
Skin : No specific data.
Eyes : No specific data.
Other information : Not available.
12. Ecological information
Environmental effects : This material is harmful to aquatic life.
Aquatic ecotoxicity
Product/ingredient name Test Species Exposure Result
Ethanol Intoxication Daphnia 48 hours Acute EC50 >100 mg/L
Intoxication Daphnia 48 hours Acute EC50 9.3 mg/L
Physiology Daphnia 48 hours Acute EC50 2 mg/L
Mortality Fish 96 hours Acute LC50 13000 mg/L
Mortality Fish 96 hours Acute LC50 >100 mg/L
Mortality Daphnia 96 hours Acute LC50 >100 mg/L
Succinic acid - Daphnia 48 hours Acute EC50 374.2 mg/L
Product/ingredient name Aquatic half-life Photolysis Biodegradability
Not available.
Bioaccumulative potential
Product/ingredient name LogPow BCF Potential
Not available.
Mobility : Not available.
Other adverse effects : No known significant effects or critical hazards.
13. Disposal considerations
Disposal methods : The generation of waste should be avoided or minimized wherever possible. Empty
containers or liners may retain some product residues. This material and its
container must be disposed of in a safe way. Dispose of surplus and non-recyclable
products via a licensed waste disposal contractor. Disposal of this product, solutions
and any by-products should at all times comply with the requirements of
environmental protection and waste disposal legislation and any regional local
authority requirements. Avoid dispersal of spilled material and runoff and contact
with soil, waterways, drains and sewers.
: 01/15/2008 Page: 5/6
Date of issue
Probe Reconstitution Solution
14. Transport information
International transport regulations
IMDG / IATA : Not regulated by any transport mode.
15. Regulatory information
Japan Control Law : Not regulated.
Chemical Substances Control Law (CSCL)
Ingredient name Classification
EDTA Calibration Sample Type II monitoring
Biodegradability : Not available.
Concentration of : Not available.
chemicals accumulated in
fish
Japan inventory (ENCS) : See Section 3.
Japan inventory (ISHL) : See Section 3.
Other regulations : Not available.
16. Other information
History
: 01/15/2008
Date of issue
Version :1
1
References : Not available.
Notice to reader
To the best of our knowledge, the information contained herein is accurate. However, neither the above
named supplier nor any of its subsidiaries assumes any liability whatsoever for the accuracy or completeness
of the information contained herein. Final determination of suitability of any material is the sole responsibility
of the user. All materials may present unknown hazards and should be used with caution. Although certain
hazards are described herein, we cannot guarantee that these are the only hazards that exist.
: 01/15/2008 Page: 6/6
Date of issue
Standard : JIS Z7250 (Japan)
SAFETY DATA SHEET
Target Capture Reagent
1. Product and company identification
Product name : Target Capture Reagent
Used in : APTIMA CT Assay 301088, APTIMA CT Assay TIGRIS 250-test kit 301199,
APTIMA CT Assay TIGRIS 2x50-test kit 302224, APTIMA GC Assay 301091,
APTIMA GC Assay TIGRIS 250-test kit 301196, APTIMA GC Assay TIGRIS 2x50-
test kit 302225, APTIMA Combo 2 301032, APTIMA Combo 2 TIGRIS 250-test kit
301130, PROGENSA PCA3 Assay Kit CE 302355, PROGENSA PCA3 100-
Reaction Kit 302354, PROGENSA PSA 100-Reaction Kit 302357, PCA3 ASR
302249, PSA ASR 302252.
MSDS no. : 0029
Product type : Liquid.
Supplier/Manufacturer : Gen-Probe Incorporated
10210 Genetic Center Drive
San Diego, CA 92121-4362
Emergency telephone : CHEMTREC International: (703) 527-3887
number (with hours of
operation)
Recommended use of the chemical
In vitro diagnostic.
Restrictions on use
Uses Industry category Use category Use sub- Function
category category
None identified.
2. Hazards identification
Classification of the : SPECIFIC TARGET ORGAN TOXICITY (REPEATED EXPOSURE) central nervous
system (CNS) - Category 2
substance or mixture
GHS label elements
Signal word : Warning
Hazard statements : May cause damage to organs through prolonged or repeated exposure if swallowed.
(central nervous system (CNS))
Precautionary statements
Prevention : Do not breathe vapor.
Response : Get medical attention/advice if you feel unwell.
Storage : Not applicable.
Disposal : Dispose of contents and container in accordance with all local, regional, national and
international regulations.
Symbol :
Other hazards which do not : Not available.
result in classification
Country information
Japan - Classification : Other hazardous substances.
: 01/15/2008 Page: 1/6
Date of issue
Target Capture Reagent
3. Composition/information on ingredients
Substance/mixture : Mixture
Chemical name : Not applicable.
Other means of : Not applicable.
identification
CAS number/other identifiers
CAS number : Not applicable.
ENCS number : Not applicable.
ISHL number : Not applicable.
Ingredient name % CAS number ENCS ISHL
Lithium chloride 5 - 10 7447-41-8 (1)-231 Not applicable.
Hazardous materials listed are the same in each part number in " Used In " section, however due to differing
non-hazardous components, the use of these products are not interchangeable. See package insert for
product use.
There are no additional ingredients present which, within the current knowledge of the supplier and in the
concentrations applicable, are classified as hazardous to health or the environment and hence require
reporting in this section.
Occupational exposure limits, if available, are listed in section 8.
4. First aid measures
First aid measures
Eye contact : Check for and remove any contact lenses. In case of contact with eyes, rinse
immediately with plenty of water. Get medical attention.
Skin contact : In case of contact, immediately flush skin with plenty of water for at least 20 minutes.
Get medical attention.
Inhalation : If inhaled, remove to fresh air. If not breathing, give artificial respiration. Get medical
attention.
Ingestion : Do not induce vomiting. Never give anything by mouth to an unconscious person.
Get medical attention.
Protection of first-aiders : No action shall be taken involving any personal risk or without suitable training. It
may be dangerous to the person providing aid to give mouth-to-mouth resuscitation.
Notes to physician : In case of inhalation of decomposition products in a fire, symptoms may be delayed.
The exposed person may need to be kept under medical surveillance for 48 hours.
See section 11 for more detailed information on health effects and symptoms.
5. Fire-fighting measures
Extinguishing media
Suitable : Use an extinguishing agent suitable for the surrounding fire.
Not suitable : None known.
Hazardous thermal : Decomposition products may include the following materials:
carbon dioxide
decomposition products
carbon monoxide
nitrogen oxides
sulfur oxides
halogenated compounds
metal oxide/oxides
Special protective : Fire-fighters should wear appropriate protective equipment and self-contained
breathing apparatus (SCBA) with a full face-piece operated in positive pressure
equipment for fire-fighters
mode.
Remark : Not available.
: 01/15/2008 Page: 2/6
Date of issue
Target Capture Reagent
6. Accidental release measures
Personal precautions, : No action shall be taken involving any personal risk or without suitable training.
Evacuate surrounding areas. Keep unnecessary and unprotected personnel from
protective equipment and
entering. Do not touch or walk through spilled material. Do not breathe vapor or
emergency procedures
mist. Provide adequate ventilation. Wear appropriate respirator when ventilation is
inadequate. Put on appropriate personal protective equipment (see section 8).
Environmental precautions : Avoid dispersal of spilled material and runoff and contact with soil, waterways, drains
and sewers. Inform the relevant authorities if the product has caused environmental
pollution (sewers, waterways, soil or air).
Methods and materials for containment and cleaning up
Small spill : Stop leak if without risk. Move containers from spill area. Dilute with water and mop
up if water-soluble or absorb with an inert dry material and place in an appropriate
waste disposal container. Dispose of via a licensed waste disposal contractor.
Large spill : Stop leak if without risk. Move containers from spill area. Approach release from
upwind. Prevent entry into sewers, water courses, basements or confined areas.
Wash spillages into an effluent treatment plant or proceed as follows. Contain and
collect spillage with non-combustible, absorbent material e.g. sand, earth, vermiculite
or diatomaceous earth and place in container for disposal according to local
regulations (see section 13). Dispose of via a licensed waste disposal contractor.
Contaminated absorbent material may pose the same hazard as the spilled product.
Note: see section 1 for emergency contact information and section 13 for waste
disposal.
7. Handling and storage
Precautions for safe : Put on appropriate personal protective equipment (see section 8). Eating, drinking
and smoking should be prohibited in areas where this material is handled, stored and
handling
processed. Workers should wash hands and face before eating, drinking and
smoking. Do not breathe vapor or mist. Do not ingest. Avoid contact with eyes, skin
and clothing. Keep in the original container or an approved alternative made from a
compatible material, kept tightly closed when not in use. Empty containers retain
product residue and can be hazardous. Do not reuse container.
Conditions for safe storage : Store in accordance with local regulations. Store in original container protected from
direct sunlight in a dry, cool and well-ventilated area, away from incompatible
materials (see section 10) and food and drink. Keep container tightly closed and
sealed until ready for use. Containers that have been opened must be carefully
resealed and kept upright to prevent leakage. Do not store in unlabeled containers.
Use appropriate containment to avoid environmental contamination.
8. Exposure controls/personal protection
Control parameters
Ingredient name Exposure limits
None.
Recommended monitoring : If this product contains ingredients with exposure limits, personal, workplace
atmosphere or biological monitoring may be required to determine the effectiveness
procedures
of the ventilation or other control measures and/or the necessity to use respiratory
protective equipment.
Appropriate engineering : If user operations generate dust, fumes, gas, vapor or mist, use process enclosures,
local exhaust ventilation or other engineering controls to keep worker exposure to
controls
airborne contaminants below any recommended or statutory limits.
Environmental exposure : Emissions from ventilation or work process equipment should be checked to ensure
they comply with the requirements of environmental protection legislation. In some
controls
cases, fume scrubbers, filters or engineering modifications to the process equipment
will be necessary to reduce emissions to acceptable levels.
Individual protection measures
: 01/15/2008 Page: 3/6
Date of issue
Target Capture Reagent
8. Exposure controls/personal protection
Hygiene measures : Wash hands, forearms and face thoroughly after handling chemical products, before
eating, smoking and using the lavatory and at the end of the working period.
Appropriate techniques should be used to remove potentially contaminated clothing.
Wash contaminated clothing before reusing. Ensure that eyewash stations and
safety showers are close to the workstation location.
Respiratory protection : Use a properly fitted, air-purifying or supplied air respirator complying with an
approved standard if a risk assessment indicates this is necessary. Respirator
selection must be based on known or anticipated exposure levels, the hazards of the
product and the safe working limits of the selected respirator.
Hand protection : Chemical-resistant, impervious gloves complying with an approved standard should
be worn at all times when handling chemical products if a risk assessment indicates
this is necessary.
Eye protection : Safety eyewear complying with an approved standard should be used when a risk
assessment indicates this is necessary to avoid exposure to liquid splashes, mists,
gases or dusts.
Skin protection : Personal protective equipment for the body should be selected based on the task
being performed and the risks involved and should be approved by a specialist
before handling this product.
9. Physical and chemical properties
Appearance
Physical state : Liquid. [Suspension.]
Color : Brown.
pH : ~ 6.4.
Flammability (solid, gas) : Non-flammable in the presence of the following materials or conditions: open flames,
sparks and static discharge, heat, shocks and mechanical impacts, oxidizing
materials, reducing materials, combustible materials, organic materials, metals,
acids, alkalis and moisture.
10. Stability and reactivity
Chemical stability : The product is stable. Under normal conditions of storage and use, hazardous
polymerization will not occur.
Conditions to avoid : No specific data.
Incompatible materials : No specific data.
Hazardous decomposition : Under normal conditions of storage and use, hazardous decomposition products
products should not be produced.
11. Toxicological information
Most important health effects
Potential acute health effects
Inhalation : Exposure to decomposition products may cause a health hazard. Serious effects
may be delayed following exposure.
Ingestion : No known significant effects or critical hazards.
Skin contact : No known significant effects or critical hazards.
Eye contact : No known significant effects or critical hazards.
Potential chronic health effects
General : May cause damage to organs through prolonged or repeated exposure.
: 01/15/2008 Page: 4/6
Date of issue
Target Capture Reagent
11. Toxicological information
Inhalation : No known significant effects or critical hazards.
Ingestion : May cause damage to organs through prolonged or repeated exposure if swallowed.
Skin contact : No known significant effects or critical hazards.
Eye contact : No known significant effects or critical hazards.
Carcinogenicity : No known significant effects or critical hazards.
Mutagenicity : No known significant effects or critical hazards.
Teratogenicity : No known significant effects or critical hazards.
Developmental effects : No known significant effects or critical hazards.
Fertility effects : No known significant effects or critical hazards.
Symptoms related to the physical, chemical and toxicological characteristics
Inhalation : No specific data.
Ingestion : No specific data.
Skin : No specific data.
Eyes : No specific data.
Other information : Not available.
12. Ecological information
Environmental effects : No known significant effects or critical hazards.
Aquatic ecotoxicity
Product/ingredient name Test Species Exposure Result
Not available.
Product/ingredient name Aquatic half-life Photolysis Biodegradability
Not available.
Bioaccumulative potential
Product/ingredient name LogPow BCF Potential
Not available.
Mobility : Not available.
Other adverse effects : No known significant effects or critical hazards.
13. Disposal considerations
Disposal methods : The generation of waste should be avoided or minimized wherever possible. Empty
containers or liners may retain some product residues. This material and its
container must be disposed of in a safe way. Dispose of surplus and non-recyclable
products via a licensed waste disposal contractor. Disposal of this product, solutions
and any by-products should at all times comply with the requirements of
environmental protection and waste disposal legislation and any regional local
authority requirements. Avoid dispersal of spilled material and runoff and contact
with soil, waterways, drains and sewers.
14. Transport information
International transport regulations
IMDG / IATA : Not regulated by any transport mode.
: 01/15/2008 Page: 5/6
Date of issue
Target Capture Reagent
15. Regulatory information
Japan Control Law : Not regulated.
Chemical Substances Control Law (CSCL)
Ingredient name Classification
EDTA Calibration Sample Type II monitoring
Biodegradability : Not available.
Concentration of : Not available.
chemicals accumulated in
fish
Japan inventory (ENCS) : See Section 3.
Japan inventory (ISHL) : See Section 3.
Other regulations : Not available.
16. Other information
History
: 01/15/2008
Date of issue
Version :1
2
References : Not available.
Notice to reader
To the best of our knowledge, the information contained herein is accurate. However, neither the above
named supplier nor any of its subsidiaries assumes any liability whatsoever for the accuracy or completeness
of the information contained herein. Final determination of suitability of any material is the sole responsibility
of the user. All materials may present unknown hazards and should be used with caution. Although certain
hazards are described herein, we cannot guarantee that these are the only hazards that exist.
: 01/15/2008 Page: 6/6
Date of issue
Standard : JIS Z7250 (Japan)
SAFETY DATA SHEET
Controls
1. Product and company identification
Product name : Controls
Used in : APTIMA CT Assay 301088, APTIMA CT Assay TIGRIS 250-test kit 301199,
APTIMA CT Assay TIGRIS 2x50-test kit 302224, APTIMA GC Assay 301091,
APTIMA GC Assay TIGRIS 250-test kit 301196, APTIMA GC Assay TIGRIS 2x50-
test kit 302225, APTIMA Combo 2 301032, APTIMA Combo 2 TIGRIS 250-test kit
301130, PROGENSA PCA3 Assay Kit CE 302355, PROGENSA PCA3 Calibrators
and Controls Kit 302353, PROGENSA PSA Calibrators and Controls Kit 302356.
MSDS no. : 0035
Product type : Liquid.
Supplier/Manufacturer : Gen-Probe Incorporated
10210 Genetic Center Drive
San Diego, CA 92121-4362
Emergency telephone : CHEMTREC International: (703) 527-3887
number (with hours of
operation)
Recommended use of the chemical
In vitro diagnostic.
Restrictions on use
Uses Industry category Use category Use sub- Function
category category
None identified.
2. Hazards identification
Classification of the : Not regulated.
substance or mixture
GHS label elements
Hazard statements : No known significant effects or critical hazards.
Precautionary statements
Prevention : Not applicable.
Response : Not applicable.
Storage : Not applicable.
Disposal : Not applicable.
Other hazards which do not : Not available.
result in classification
Country information
Japan - Classification : Not applicable.
3. Composition/information on ingredients
Substance/mixture : Mixture
Chemical name : Not applicable.
Other means of : Not applicable.
identification
CAS number/other identifiers
CAS number : Not applicable.
ENCS number : Not applicable.
ISHL number : Not applicable.
: 12/01/2007 Page: 1/6
Date of issue
Controls
3. Composition/information on ingredients
Ingredient name % CAS number ENCS ISHL
None.
Due to differing non-hazardous components, the products listed in each part number in 鈥淯sed In鈥? section are
not interchangeable. See package insert for product use.
There are no ingredients present which, within the current knowledge of the supplier and in the concentrations
applicable, are classified as hazardous to health or the environment and hence require reporting in this
section.
Occupational exposure limits, if available, are listed in section 8.
4. First aid measures
First aid measures
Eye contact : Check for and remove any contact lenses. In case of contact with eyes, rinse
immediately with plenty of water. Get medical attention if symptoms occur.
Skin contact : Wash with soap and water. Get medical attention if symptoms occur.
Inhalation : If inhaled, remove to fresh air. If not breathing, give artificial respiration. Get medical
attention if symptoms appear.
Ingestion : Do not induce vomiting. Never give anything by mouth to an unconscious person.
Get medical attention if symptoms appear.
Protection of first-aiders : No action shall be taken involving any personal risk or without suitable training.
Notes to physician : No specific treatment. Treat symptomatically. Contact poison treatment specialist
immediately if large quantities have been ingested or inhaled.
See section 11 for more detailed information on health effects and symptoms.
5. Fire-fighting measures
Extinguishing media
Suitable : Use an extinguishing agent suitable for the surrounding fire.
Not suitable : None known.
Hazardous thermal : Decomposition products may include the following materials:
carbon dioxide
decomposition products
carbon monoxide
sulfur oxides
metal oxide/oxides
Special protective : Fire-fighters should wear appropriate protective equipment and self-contained
breathing apparatus (SCBA) with a full face-piece operated in positive pressure
equipment for fire-fighters
mode.
Remark : Not available.
6. Accidental release measures
Personal precautions, : No action shall be taken involving any personal risk or without suitable training.
Evacuate surrounding areas. Keep unnecessary and unprotected personnel from
protective equipment and
entering. Do not touch or walk through spilled material. Avoid breathing vapor or
emergency procedures
mist. Provide adequate ventilation. Wear appropriate respirator when ventilation is
inadequate. Put on appropriate personal protective equipment (see section 8).
Environmental precautions : Avoid dispersal of spilled material and runoff and contact with soil, waterways, drains
and sewers. Inform the relevant authorities if the product has caused environmental
pollution (sewers, waterways, soil or air).
Methods and materials for containment and cleaning up
Small spill : Stop leak if without risk. Move containers from spill area. Dilute with water and mop
up if water-soluble or absorb with an inert dry material and place in an appropriate
waste disposal container. Dispose of via a licensed waste disposal contractor.
: 12/01/2007 Page: 2/6
Date of issue
Controls
6. Accidental release measures
Large spill : Stop leak if without risk. Move containers from spill area. Approach release from
upwind. Prevent entry into sewers, water courses, basements or confined areas.
Wash spillages into an effluent treatment plant or proceed as follows. Contain and
collect spillage with non-combustible, absorbent material e.g. sand, earth, vermiculite
or diatomaceous earth and place in container for disposal according to local
regulations (see section 13). Dispose of via a licensed waste disposal contractor.
Contaminated absorbent material may pose the same hazard as the spilled product.
Note: see section 1 for emergency contact information and section 13 for waste
disposal.
7. Handling and storage
Precautions for safe : Put on appropriate personal protective equipment (see section 8). Eating, drinking
and smoking should be prohibited in areas where this material is handled, stored and
handling
processed. Workers should wash hands and face before eating, drinking and
smoking. Do not ingest. Avoid contact with eyes, skin and clothing. Avoid breathing
vapor or mist. Keep in the original container or an approved alternative made from a
compatible material, kept tightly closed when not in use. Empty containers retain
product residue and can be hazardous. Do not reuse container.
Conditions for safe storage : Store in accordance with local regulations. Store in original container protected from
direct sunlight in a dry, cool and well-ventilated area, away from incompatible
materials (see section 10) and food and drink. Keep container tightly closed and
sealed until ready for use. Containers that have been opened must be carefully
resealed and kept upright to prevent leakage. Do not store in unlabeled containers.
Use appropriate containment to avoid environmental contamination.
8. Exposure controls/personal protection
Control parameters
Ingredient name Exposure limits
None.
Recommended monitoring : If this product contains ingredients with exposure limits, personal, workplace
atmosphere or biological monitoring may be required to determine the effectiveness
procedures
of the ventilation or other control measures and/or the necessity to use respiratory
protective equipment.
Appropriate engineering : No special ventilation requirements. Good general ventilation should be sufficient to
control worker exposure to airborne contaminants. If this product contains
controls
ingredients with exposure limits, use process enclosures, local exhaust ventilation or
other engineering controls to keep worker exposure below any recommended or
statutory limits.
Environmental exposure : Emissions from ventilation or work process equipment should be checked to ensure
they comply with the requirements of environmental protection legislation. In some
controls
cases, fume scrubbers, filters or engineering modifications to the process equipment
will be necessary to reduce emissions to acceptable levels.
Individual protection measures
Hygiene measures : Wash hands, forearms and face thoroughly after handling chemical products, before
eating, smoking and using the lavatory and at the end of the working period.
Appropriate techniques should be used to remove potentially contaminated clothing.
Wash contaminated clothing before reusing. Ensure that eyewash stations and
safety showers are close to the workstation location.
Respiratory protection : Use a properly fitted, air-purifying or supplied air respirator complying with an
approved standard if a risk assessment indicates this is necessary. Respirator
selection must be based on known or anticipated exposure levels, the hazards of the
product and the safe working limits of the selected respirator.
: 12/01/2007 Page: 3/6
Date of issue
Controls
8. Exposure controls/personal protection
Hand protection : Chemical-resistant, impervious gloves complying with an approved standard should
be worn at all times when handling chemical products if a risk assessment indicates
this is necessary.
Eye protection : Safety eyewear complying with an approved standard should be used when a risk
assessment indicates this is necessary to avoid exposure to liquid splashes, mists,
gases or dusts.
Skin protection : Personal protective equipment for the body should be selected based on the task
being performed and the risks involved and should be approved by a specialist
before handling this product.
9. Physical and chemical properties
Appearance
Physical state : Liquid.
Color : Colorless.
pH : ~ 6.7.
Flammability (solid, gas) : Non-flammable in the presence of the following materials or conditions: open flames,
sparks and static discharge, heat, shocks and mechanical impacts, oxidizing
materials, reducing materials, combustible materials, organic materials, metals,
acids, alkalis and moisture.
10. Stability and reactivity
Chemical stability : The product is stable. Under normal conditions of storage and use, hazardous
polymerization will not occur.
Conditions to avoid : No specific data.
Incompatible materials : No specific data.
Hazardous decomposition : Under normal conditions of storage and use, hazardous decomposition products
products should not be produced.
11. Toxicological information
Most important health effects
Potential acute health effects
Inhalation : No known significant effects or critical hazards.
Ingestion : No known significant effects or critical hazards.
Skin contact : No known significant effects or critical hazards.
Eye contact : No known significant effects or critical hazards.
Potential chronic health effects
General : No known significant effects or critical hazards.
Inhalation : No known significant effects or critical hazards.
Ingestion : No known significant effects or critical hazards.
Skin contact : No known significant effects or critical hazards.
Eye contact : No known significant effects or critical hazards.
Carcinogenicity : No known significant effects or critical hazards.
Mutagenicity : No known significant effects or critical hazards.
Teratogenicity : No known significant effects or critical hazards.
Developmental effects : No known significant effects or critical hazards.
: 12/01/2007 Page: 4/6
Date of issue
Controls
11. Toxicological information
Fertility effects : No known significant effects or critical hazards.
Symptoms related to the physical, chemical and toxicological characteristics
Inhalation : No specific data.
Ingestion : No specific data.
Skin : No specific data.
Eyes : No specific data.
Other information : Not available.
12. Ecological information
Environmental effects : No known significant effects or critical hazards.
Aquatic ecotoxicity
Product/ingredient name Test Species Exposure Result
Not available.
Product/ingredient name Aquatic half-life Photolysis Biodegradability
Not available.
Bioaccumulative potential
Product/ingredient name LogPow BCF Potential
Not available.
Mobility : Not available.
Other adverse effects : No known significant effects or critical hazards.
13. Disposal considerations
Disposal methods : The generation of waste should be avoided or minimized wherever possible. Empty
containers or liners may retain some product residues. This material and its
container must be disposed of in a safe way. Dispose of surplus and non-recyclable
products via a licensed waste disposal contractor. Disposal of this product, solutions
and any by-products should at all times comply with the requirements of
environmental protection and waste disposal legislation and any regional local
authority requirements. Avoid dispersal of spilled material and runoff and contact
with soil, waterways, drains and sewers.
14. Transport information
International transport regulations
IMDG / IATA : Not regulated by any transport mode.
15. Regulatory information
Japan Control Law : Not regulated.
Chemical Substances Control Law (CSCL)
Ingredient name Classification
Biodegradability : Not available.
Concentration of : Not available.
chemicals accumulated in
fish
Japan inventory (ENCS) : See Section 3.
Japan inventory (ISHL) : See Section 3.
Other regulations : Not available.
: 12/01/2007 Page: 5/6
Date of issue
Controls
16. Other information
History
: 12/01/2007
Date of issue
Version :1
0
References : Not available.
Notice to reader
To the best of our knowledge, the information contained herein is accurate. However, neither the above
named supplier nor any of its subsidiaries assumes any liability whatsoever for the accuracy or completeness
of the information contained herein. Final determination of suitability of any material is the sole responsibility
of the user. All materials may present unknown hazards and should be used with caution. Although certain
hazards are described herein, we cannot guarantee that these are the only hazards that exist.
: 12/01/2007 Page: 6/6
Date of issue
Standard : JIS Z7250 (Japan)
SAFETY DATA SHEET
Selection Reagent
1. Product and company identification
Product name : Selection Reagent
Used in : APTIMA CT Assay 301088, APTIMA CT Assay TIGRIS 250-test kit 301199,
APTIMA CT Assay TIGRIS 2x50-test kit 302224, APTIMA GC Assay 301091,
APTIMA GC Assay TIGRIS 250-test kit 301196, APTIMA GC Assay TIGRIS 2x50-
test kit 302225, APTIMA Combo 2 301032, APTIMA Combo 2 TIGRIS 250-test kit
301130, PROGENSA PCA3 Assay Kit CE 302355, PROGENSA PCA3 100-
Reaction Kit 302354, PROGENSA PSA 100-Reaction Kit 302357, PCA3/PSA
Supplemental Fluids Kit 302030.
MSDS no. : 0038
Product type : Liquid.
Supplier/Manufacturer : Gen-Probe Incorporated
10210 Genetic Center Drive
San Diego, CA 92121-4362
Emergency telephone : CHEMTREC International: (703) 527-3887
number (with hours of
operation)
Recommended use of the chemical
In vitro diagnostic.
Restrictions on use
Uses Industry category Use category Use sub- Function
category category
None identified.
2. Hazards identification
Classification of the : SPECIFIC TARGET ORGAN TOXICITY (REPEATED EXPOSURE) central nervous
system (CNS), kidneys and liver - Category 2
substance or mixture
GHS label elements
Signal word : Warning
Hazard statements : May cause damage to organs through prolonged or repeated exposure if swallowed.
(central nervous system (CNS), kidneys, liver)
Precautionary statements
Prevention : Do not breathe vapor.
Response : Get medical attention/advice if you feel unwell.
Storage : Not applicable.
Disposal : Dispose of contents and container in accordance with all local, regional, national and
international regulations.
Symbol :
Other hazards which do not : Not available.
result in classification
Country information
Japan - Classification : Other hazardous substances.
: 01/15/2008 Page: 1/6
Date of issue
Selection Reagent
3. Composition/information on ingredients
Substance/mixture : Mixture
Chemical name : Not applicable.
Other means of : Not applicable.
identification
CAS number/other identifiers
CAS number : Not applicable.
ENCS number : Not applicable.
ISHL number : Not applicable.
Ingredient name % CAS number ENCS ISHL
Boric Acid 1-5 10043-35-3 (1)-63 Not available.
Triton X-100 1-5 9002-93-1 Not available. Not available.
Hazardous materials listed are the same in each part number in " Used In " section, however due to differing
non-hazardous components, the use of these products are not interchangeable. See package insert for
product use.
There are no additional ingredients present which, within the current knowledge of the supplier and in the
concentrations applicable, are classified as hazardous to health or the environment and hence require
reporting in this section.
Occupational exposure limits, if available, are listed in section 8.
4. First aid measures
First aid measures
Eye contact : Check for and remove any contact lenses. In case of contact with eyes, rinse
immediately with plenty of water. Get medical attention if symptoms occur.
Skin contact : Wash with soap and water. Get medical attention if symptoms occur.
Inhalation : If inhaled, remove to fresh air. If not breathing, give artificial respiration. Get medical
attention if symptoms appear.
Ingestion : Do not induce vomiting. Never give anything by mouth to an unconscious person.
Get medical attention if symptoms appear.
Protection of first-aiders : No action shall be taken involving any personal risk or without suitable training. It
may be dangerous to the person providing aid to give mouth-to-mouth resuscitation.
Notes to physician : No specific treatment. Treat symptomatically. Contact poison treatment specialist
immediately if large quantities have been ingested or inhaled.
See section 11 for more detailed information on health effects and symptoms.
5. Fire-fighting measures
Extinguishing media
Suitable : Use an extinguishing agent suitable for the surrounding fire.
Not suitable : None known.
Hazardous thermal : Decomposition products may include the following materials:
carbon dioxide
decomposition products
carbon monoxide
Special protective : Fire-fighters should wear appropriate protective equipment and self-contained
breathing apparatus (SCBA) with a full face-piece operated in positive pressure
equipment for fire-fighters
mode.
Remark : Not available.
: 01/15/2008 Page: 2/6
Date of issue
Selection Reagent
6. Accidental release measures
Personal precautions, : No action shall be taken involving any personal risk or without suitable training.
Evacuate surrounding areas. Keep unnecessary and unprotected personnel from
protective equipment and
entering. Do not touch or walk through spilled material. Do not breathe vapor or
emergency procedures
mist. Provide adequate ventilation. Wear appropriate respirator when ventilation is
inadequate. Put on appropriate personal protective equipment (see section 8).
Environmental precautions : Avoid dispersal of spilled material and runoff and contact with soil, waterways, drains
and sewers. Inform the relevant authorities if the product has caused environmental
pollution (sewers, waterways, soil or air).
Methods and materials for containment and cleaning up
Small spill : Stop leak if without risk. Move containers from spill area. Dilute with water and mop
up if water-soluble or absorb with an inert dry material and place in an appropriate
waste disposal container. Dispose of via a licensed waste disposal contractor.
Large spill : Stop leak if without risk. Move containers from spill area. Approach release from
upwind. Prevent entry into sewers, water courses, basements or confined areas.
Wash spillages into an effluent treatment plant or proceed as follows. Contain and
collect spillage with non-combustible, absorbent material e.g. sand, earth, vermiculite
or diatomaceous earth and place in container for disposal according to local
regulations (see section 13). Dispose of via a licensed waste disposal contractor.
Contaminated absorbent material may pose the same hazard as the spilled product.
Note: see section 1 for emergency contact information and section 13 for waste
disposal.
7. Handling and storage
Precautions for safe : Put on appropriate personal protective equipment (see section 8). Eating, drinking
and smoking should be prohibited in areas where this material is handled, stored and
handling
processed. Workers should wash hands and face before eating, drinking and
smoking. Do not breathe vapor or mist. Do not ingest. Avoid contact with eyes, skin
and clothing. Keep in the original container or an approved alternative made from a
compatible material, kept tightly closed when not in use. Empty containers retain
product residue and can be hazardous. Do not reuse container.
Conditions for safe storage : Store in accordance with local regulations. Store in original container protected from
direct sunlight in a dry, cool and well-ventilated area, away from incompatible
materials (see section 10) and food and drink. Keep container tightly closed and
sealed until ready for use. Containers that have been opened must be carefully
resealed and kept upright to prevent leakage. Do not store in unlabeled containers.
Use appropriate containment to avoid environmental contamination.
8. Exposure controls/personal protection
Control parameters
Ingredient name Exposure limits
None.
Recommended monitoring : If this product contains ingredients with exposure limits, personal, workplace
atmosphere or biological monitoring may be required to determine the effectiveness
procedures
of the ventilation or other control measures and/or the necessity to use respiratory
protective equipment.
Appropriate engineering : If user operations generate dust, fumes, gas, vapor or mist, use process enclosures,
local exhaust ventilation or other engineering controls to keep worker exposure to
controls
airborne contaminants below any recommended or statutory limits.
Environmental exposure : Emissions from ventilation or work process equipment should be checked to ensure
they comply with the requirements of environmental protection legislation. In some
controls
cases, fume scrubbers, filters or engineering modifications to the process equipment
will be necessary to reduce emissions to acceptable levels.
Individual protection measures
: 01/15/2008 Page: 3/6
Date of issue
Selection Reagent
8. Exposure controls/personal protection
Hygiene measures : Wash hands, forearms and face thoroughly after handling chemical products, before
eating, smoking and using the lavatory and at the end of the working period.
Appropriate techniques should be used to remove potentially contaminated clothing.
Wash contaminated clothing before reusing. Ensure that eyewash stations and
safety showers are close to the workstation location.
Respiratory protection : Use a properly fitted, air-purifying or supplied air respirator complying with an
approved standard if a risk assessment indicates this is necessary. Respirator
selection must be based on known or anticipated exposure levels, the hazards of the
product and the safe working limits of the selected respirator.
Hand protection : Chemical-resistant, impervious gloves complying with an approved standard should
be worn at all times when handling chemical products if a risk assessment indicates
this is necessary.
Eye protection : Safety eyewear complying with an approved standard should be used when a risk
assessment indicates this is necessary to avoid exposure to liquid splashes, mists,
gases or dusts.
Skin protection : Personal protective equipment for the body should be selected based on the task
being performed and the risks involved and should be approved by a specialist
before handling this product.
9. Physical and chemical properties
Appearance
Physical state : Liquid. [Clear.]
Color : Colorless.
pH : 8.5
Flammability (solid, gas) : Non-flammable in the presence of the following materials or conditions: open flames,
sparks and static discharge, heat, shocks and mechanical impacts, oxidizing
materials, reducing materials, combustible materials, organic materials, metals,
acids, alkalis and moisture.
10. Stability and reactivity
Chemical stability : The product is stable. Under normal conditions of storage and use, hazardous
polymerization will not occur.
Conditions to avoid : No specific data.
Incompatible materials : No specific data.
Hazardous decomposition : Under normal conditions of storage and use, hazardous decomposition products
products should not be produced.
11. Toxicological information
Most important health effects
Potential acute health effects
Inhalation : No known significant effects or critical hazards.
Ingestion : No known significant effects or critical hazards.
Skin contact : No known significant effects or critical hazards.
Eye contact : No known significant effects or critical hazards.
Potential chronic health effects
General : May cause damage to organs through prolonged or repeated exposure.
Inhalation : No known significant effects or critical hazards.
: 01/15/2008 Page: 4/6
Date of issue
Selection Reagent
11. Toxicological information
Ingestion : May cause damage to organs through prolonged or repeated exposure if swallowed.
Skin contact : No known significant effects or critical hazards.
Eye contact : No known significant effects or critical hazards.
Carcinogenicity : No known significant effects or critical hazards.
Mutagenicity : No known significant effects or critical hazards.
Teratogenicity : No known significant effects or critical hazards.
Developmental effects : No known significant effects or critical hazards.
Fertility effects : No known significant effects or critical hazards.
Symptoms related to the physical, chemical and toxicological characteristics
Inhalation : No specific data.
Ingestion : No specific data.
Skin : No specific data.
Eyes : No specific data.
Other information : Not available.
12. Ecological information
Environmental effects : No known significant effects or critical hazards.
Aquatic ecotoxicity
Product/ingredient name Test Species Exposure Result
Boric Acid Intoxication Daphnia 48 hours Acute EC50 777 mg/L
Intoxication Daphnia 48 hours Acute EC50 226 mg/L
Intoxication Daphnia 48 hours Acute EC50 133 mg/L
Mortality Fish 96 hours Acute LC50 >1100 mg/L
Mortality Fish 96 hours Acute LC50 >1021 mg/L
Mortality Fish 96 hours Acute LC50 >800 mg/L
Triton X-100 Mortality Fish 96 hours Acute LC50 531 mg/L
Mortality Fish 96 hours Acute LC50 12 mg/L
Mortality Fish 96 hours Acute LC50 >10 mg/L
Mortality Fish 96 hours Acute LC50 6 mg/L
Mortality Fish 96 hours Acute LC50 5.38 mg/L
Mortality Fish 96 hours Acute LC50 4.5 mg/L
Product/ingredient name Aquatic half-life Photolysis Biodegradability
Not available.
Bioaccumulative potential
Product/ingredient name LogPow BCF Potential
Not available.
Mobility : Not available.
Other adverse effects : No known significant effects or critical hazards.
13. Disposal considerations
Disposal methods : The generation of waste should be avoided or minimized wherever possible. Empty
containers or liners may retain some product residues. This material and its
container must be disposed of in a safe way. Dispose of surplus and non-recyclable
products via a licensed waste disposal contractor. Disposal of this product, solutions
and any by-products should at all times comply with the requirements of
environmental protection and waste disposal legislation and any regional local
authority requirements. Avoid dispersal of spilled material and runoff and contact
with soil, waterways, drains and sewers.
: 01/15/2008 Page: 5/6
Date of issue
Selection Reagent
14. Transport information
International transport regulations
IMDG / IATA : Not regulated by any transport mode.
15. Regulatory information
Japan Control Law : Not regulated.
Chemical Substances Control Law (CSCL)
Ingredient name Classification
Triton X-100 Type III monitoring
Biodegradability : Not available.
Concentration of : Not available.
chemicals accumulated in
fish
Japan inventory (ENCS) : See Section 3.
Japan inventory (ISHL) : See Section 3.
Other regulations : Not available.
16. Other information
History
: 01/15/2008
Date of issue
Version :1
1
References : Not available.
Notice to reader
To the best of our knowledge, the information contained herein is accurate. However, neither the above
named supplier nor any of its subsidiaries assumes any liability whatsoever for the accuracy or completeness
of the information contained herein. Final determination of suitability of any material is the sole responsibility
of the user. All materials may present unknown hazards and should be used with caution. Although certain
hazards are described herein, we cannot guarantee that these are the only hazards that exist.
: 01/15/2008 Page: 6/6
Date of issue
Standard : JIS Z7250 (Japan)
SAFETY DATA SHEET
Enzyme Reconstitution Solution
1. Product and company identification
Product name : Enzyme Reconstitution Solution
Used in : APTIMA CT Assay 301088, APTIMA CT Assay TIGRIS 250-test kit 301199,
APTIMA CT Assay TIGRIS 2x50-test kit 302224, APTIMA GC Assay 301091,
APTIMA GC Assay TIGRIS 250-test kit 301196, APTIMA GC Assay TIGRIS 2x50-
test kit 302225, APTIMA Combo 2 301032, APTIMA Combo 2 TIGRIS 250-test kit
301130, PROGENSA PCA3 Assay Kit CE 302355, PROGENSA PCA3 100-
Reaction Kit 302354, PROGENSA PSA 100-Reaction Kit 302357, PCA3/PSA
Supplemental Fluids Kit 302030.
MSDS no. : 0039
Product type : Liquid.
Supplier/Manufacturer : Gen-Probe Incorporated
10210 Genetic Center Drive
San Diego, CA 92121-4362
Emergency telephone : CHEMTREC International: (703) 527-3887
number (with hours of
operation)
Recommended use of the chemical
In vitro diagnostic.
Restrictions on use
Uses Industry category Use category Use sub- Function
category category
None identified.
2. Hazards identification
Classification of the : AQUATIC TOXICITY (ACUTE) - Category 3
substance or mixture
GHS label elements
Hazard statements : Harmful to aquatic life.
Precautionary statements
Prevention : Avoid release to the environment.
Response : Not applicable.
Storage : Not applicable.
Disposal : Dispose of contents and container in accordance with all local, regional, national and
international regulations.
Other hazards which do not : Not available.
result in classification
Country information
Japan - Classification : Other hazardous substances.
3. Composition/information on ingredients
Substance/mixture : Mixture
Chemical name : Not applicable.
Other means of : Not applicable.
identification
CAS number/other identifiers
CAS number : Not applicable.
ENCS number : Not applicable.
: 01/15/2008 Page: 1/6
Date of issue
Enzyme Reconstitution Solution
3. Composition/information on ingredients
ISHL number : Not applicable.
Ingredient name % CAS number ENCS ISHL
Triton X-100 5 - 10 9002-93-1 Not available. Not applicable.
Hazardous materials listed are the same in each part number in " Used In " section, however due to differing
non-hazardous components, the use of these products are not interchangeable. See package insert for
product use.
There are no additional ingredients present which, within the current knowledge of the supplier and in the
concentrations applicable, are classified as hazardous to health or the environment and hence require
reporting in this section.
Occupational exposure limits, if available, are listed in section 8.
4. First aid measures
First aid measures
Eye contact : Check for and remove any contact lenses. In case of contact with eyes, rinse
immediately with plenty of water. Get medical attention if symptoms occur.
Skin contact : Wash with soap and water. Get medical attention if symptoms occur.
Inhalation : If inhaled, remove to fresh air. If not breathing, give artificial respiration. Get medical
attention if symptoms appear.
Ingestion : Do not induce vomiting. Never give anything by mouth to an unconscious person.
Get medical attention if symptoms appear.
Protection of first-aiders : No action shall be taken involving any personal risk or without suitable training. It
may be dangerous to the person providing aid to give mouth-to-mouth resuscitation.
Notes to physician : In case of inhalation of decomposition products in a fire, symptoms may be delayed.
The exposed person may need to be kept under medical surveillance for 48 hours.
See section 11 for more detailed information on health effects and symptoms.
5. Fire-fighting measures
Extinguishing media
Suitable : Use an extinguishing agent suitable for the surrounding fire.
Not suitable : None known.
Hazardous thermal : Decomposition products may include the following materials:
carbon dioxide
decomposition products
carbon monoxide
nitrogen oxides
sulfur oxides
Special protective : Fire-fighters should wear appropriate protective equipment and self-contained
breathing apparatus (SCBA) with a full face-piece operated in positive pressure
equipment for fire-fighters
mode.
Remark : Not available.
6. Accidental release measures
Personal precautions, : No action shall be taken involving any personal risk or without suitable training.
Evacuate surrounding areas. Keep unnecessary and unprotected personnel from
protective equipment and
entering. Do not touch or walk through spilled material. Do not breathe vapor or
emergency procedures
mist. Provide adequate ventilation. Wear appropriate respirator when ventilation is
inadequate. Put on appropriate personal protective equipment (see section 8).
Environmental precautions : Avoid dispersal of spilled material and runoff and contact with soil, waterways, drains
and sewers. Inform the relevant authorities if the product has caused environmental
pollution (sewers, waterways, soil or air). Water polluting material. May be harmful
to the environment if released in large quantities.
: 01/15/2008 Page: 2/6
Date of issue
Enzyme Reconstitution Solution
6. Accidental release measures
Methods and materials for containment and cleaning up
Small spill : Stop leak if without risk. Move containers from spill area. Dilute with water and mop
up if water-soluble or absorb with an inert dry material and place in an appropriate
waste disposal container. Dispose of via a licensed waste disposal contractor.
Large spill : Stop leak if without risk. Move containers from spill area. Approach release from
upwind. Prevent entry into sewers, water courses, basements or confined areas.
Wash spillages into an effluent treatment plant or proceed as follows. Contain and
collect spillage with non-combustible, absorbent material e.g. sand, earth, vermiculite
or diatomaceous earth and place in container for disposal according to local
regulations (see section 13). Dispose of via a licensed waste disposal contractor.
Contaminated absorbent material may pose the same hazard as the spilled product.
Note: see section 1 for emergency contact information and section 13 for waste
disposal.
7. Handling and storage
Precautions for safe : Put on appropriate personal protective equipment (see section 8). Eating, drinking
and smoking should be prohibited in areas where this material is handled, stored and
handling
processed. Workers should wash hands and face before eating, drinking and
smoking. Do not breathe vapor or mist. Do not ingest. Avoid contact with eyes, skin
and clothing. Avoid release to the environment. Keep in the original container or an
approved alternative made from a compatible material, kept tightly closed when not
in use. Empty containers retain product residue and can be hazardous. Do not
reuse container.
Conditions for safe storage : Store in accordance with local regulations. Store in original container protected from
direct sunlight in a dry, cool and well-ventilated area, away from incompatible
materials (see section 10) and food and drink. Keep container tightly closed and
sealed until ready for use. Containers that have been opened must be carefully
resealed and kept upright to prevent leakage. Do not store in unlabeled containers.
Use appropriate containment to avoid environmental contamination.
8. Exposure controls/personal protection
Control parameters
Ingredient name Exposure limits
None.
Recommended monitoring : If this product contains ingredients with exposure limits, personal, workplace
atmosphere or biological monitoring may be required to determine the effectiveness
procedures
of the ventilation or other control measures and/or the necessity to use respiratory
protective equipment.
Appropriate engineering : No special ventilation requirements. Good general ventilation should be sufficient to
control worker exposure to airborne contaminants. If this product contains
controls
ingredients with exposure limits, use process enclosures, local exhaust ventilation or
other engineering controls to keep worker exposure below any recommended or
statutory limits.
Environmental exposure : Emissions from ventilation or work process equipment should be checked to ensure
they comply with the requirements of environmental protection legislation. In some
controls
cases, fume scrubbers, filters or engineering modifications to the process equipment
will be necessary to reduce emissions to acceptable levels.
Individual protection measures
Hygiene measures : Wash hands, forearms and face thoroughly after handling chemical products, before
eating, smoking and using the lavatory and at the end of the working period.
Appropriate techniques should be used to remove potentially contaminated clothing.
Wash contaminated clothing before reusing. Ensure that eyewash stations and
safety showers are close to the workstation location.
: 01/15/2008 Page: 3/6
Date of issue
Enzyme Reconstitution Solution
8. Exposure controls/personal protection
Respiratory protection : Use a properly fitted, air-purifying or supplied air respirator complying with an
approved standard if a risk assessment indicates this is necessary. Respirator
selection must be based on known or anticipated exposure levels, the hazards of the
product and the safe working limits of the selected respirator.
Hand protection : Chemical-resistant, impervious gloves complying with an approved standard should
be worn at all times when handling chemical products if a risk assessment indicates
this is necessary.
Eye protection : Safety eyewear complying with an approved standard should be used when a risk
assessment indicates this is necessary to avoid exposure to liquid splashes, mists,
gases or dusts.
Skin protection : Personal protective equipment for the body should be selected based on the task
being performed and the risks involved and should be approved by a specialist
before handling this product.
9. Physical and chemical properties
Appearance
Physical state : Liquid. [Clear.]
Color : Colorless.
pH : 7.
Flammability (solid, gas) : Non-flammable in the presence of the following materials or conditions: open flames,
sparks and static discharge, heat, shocks and mechanical impacts, oxidizing
materials, reducing materials, combustible materials, organic materials, metals,
acids, alkalis and moisture.
10. Stability and reactivity
Chemical stability : The product is stable. Under normal conditions of storage and use, hazardous
polymerization will not occur.
Conditions to avoid : Avoid release to the environment.
Incompatible materials : No specific data.
Hazardous decomposition : Under normal conditions of storage and use, hazardous decomposition products
products should not be produced.
11. Toxicological information
Most important health effects
Potential acute health effects
Inhalation : Exposure to decomposition products may cause a health hazard. Serious effects
may be delayed following exposure.
Ingestion : No known significant effects or critical hazards.
Skin contact : No known significant effects or critical hazards.
Eye contact : No known significant effects or critical hazards.
Potential chronic health effects
General : No known significant effects or critical hazards.
Inhalation : No known significant effects or critical hazards.
Ingestion : No known significant effects or critical hazards.
Skin contact : No known significant effects or critical hazards.
Eye contact : No known significant effects or critical hazards.
Carcinogenicity : No known significant effects or critical hazards.
: 01/15/2008 Page: 4/6
Date of issue
Enzyme Reconstitution Solution
11. Toxicological information
Mutagenicity : No known significant effects or critical hazards.
Teratogenicity : No known significant effects or critical hazards.
Developmental effects : No known significant effects or critical hazards.
Fertility effects : No known significant effects or critical hazards.
Symptoms related to the physical, chemical and toxicological characteristics
Inhalation : No specific data.
Ingestion : No specific data.
Skin : No specific data.
Eyes : No specific data.
Other information : Not available.
12. Ecological information
Environmental effects : This material is harmful to aquatic life.
Aquatic ecotoxicity
Product/ingredient name Test Species Exposure Result
Triton X-100 Mortality Fish 96 hours Acute LC50 531 mg/L
Mortality Fish 96 hours Acute LC50 12 mg/L
Mortality Fish 96 hours Acute LC50 >10 mg/L
Mortality Fish 96 hours Acute LC50 6 mg/L
Mortality Fish 96 hours Acute LC50 5.38 mg/L
Mortality Fish 96 hours Acute LC50 4.5 mg/L
Product/ingredient name Aquatic half-life Photolysis Biodegradability
Not available.
Bioaccumulative potential
Product/ingredient name LogPow BCF Potential
Not available.
Mobility : Not available.
Other adverse effects : No known significant effects or critical hazards.
13. Disposal considerations
Disposal methods : The generation of waste should be avoided or minimized wherever possible. Empty
containers or liners may retain some product residues. This material and its
container must be disposed of in a safe way. Dispose of surplus and non-recyclable
products via a licensed waste disposal contractor. Disposal of this product, solutions
and any by-products should at all times comply with the requirements of
environmental protection and waste disposal legislation and any regional local
authority requirements. Avoid dispersal of spilled material and runoff and contact
with soil, waterways, drains and sewers.
14. Transport information
International transport regulations
IMDG / IATA : Not regulated by any transport mode.
: 01/15/2008 Page: 5/6
Date of issue
Enzyme Reconstitution Solution
15. Regulatory information
Japan Control Law : Not regulated.
Chemical Substances Control Law (CSCL)
Ingredient name Classification
Triton X-100 Type III monitoring
Ethylenediamine tetraacetic acid Type II monitoring
Biodegradability : Not available.
Concentration of : Not available.
chemicals accumulated in
fish
Japan inventory (ENCS) : See Section 3.
Japan inventory (ISHL) : See Section 3.
Other regulations : Not available.
16. Other information
History
: 01/15/2008
Date of issue
Version :1
1
References : Not available.
Notice to reader
To the best of our knowledge, the information contained herein is accurate. However, neither the above
named supplier nor any of its subsidiaries assumes any liability whatsoever for the accuracy or completeness
of the information contained herein. Final determination of suitability of any material is the sole responsibility
of the user. All materials may present unknown hazards and should be used with caution. Although certain
hazards are described herein, we cannot guarantee that these are the only hazards that exist.
: 01/15/2008 Page: 6/6
Date of issue
Standard : JIS Z7250 (Japan)
SAFETY DATA SHEET
Enzyme Reagent
1. Product and company identification
Product name : Enzyme Reagent
Used in : APTIMA CT Assay 301088, APTIMA CT Assay TIGRIS 250-test kit 301199,
APTIMA CT Assay TIGRIS 2x50-test kit 302224, APTIMA GC Assay 301091,
APTIMA GC Assay TIGRIS 250-test kit 301196, APTIMA GC Assay TIGRIS 2x50-
test kit 302225, APTIMA Combo 2 301032, APTIMA Combo 2 TIGRIS 250-test kit
301130, PROGENSA PCA3 Assay Kit CE 302355, PROGENSA PCA3 100-
Reaction Kit 302354, PROGENSA PSA 100-Reaction Kit 302357, PCA3/PSA
Supplemental Fluids Kit 302030.
MSDS no. : 0040
Product type : Solid.
Supplier/Manufacturer : Gen-Probe Incorporated
10210 Genetic Center Drive
San Diego, CA 92121-4362
Emergency telephone : CHEMTREC International: (703) 527-3887
number (with hours of
operation)
Recommended use of the chemical
In vitro diagnostic.
Restrictions on use
Uses Industry category Use category Use sub- Function
category category
None identified.
2. Hazards identification
Classification of the : Not regulated.
substance or mixture
GHS label elements
Hazard statements : No known significant effects or critical hazards.
Precautionary statements
Prevention : Not applicable.
Response : Not applicable.
Storage : Not applicable.
Disposal : Not applicable.
Other hazards which do not : Not available.
result in classification
Country information
Japan - Classification : Other hazardous substances.
3. Composition/information on ingredients
Substance/mixture : Mixture
Chemical name : Not applicable.
Other means of : Not applicable.
identification
CAS number/other identifiers
CAS number : Not applicable.
ENCS number : Not applicable.
ISHL number : Not applicable.
: 01/15/2008 Page: 1/6
Date of issue
Enzyme Reagent
3. Composition/information on ingredients
Ingredient name % CAS number ENCS ISHL
None.
Due to differing non-hazardous components, the products listed in each part number in 鈥淯sed In鈥? section are
not interchangeable. See package insert for product use.
There are no additional ingredients present which, within the current knowledge of the supplier and in the
concentrations applicable, are classified as hazardous to health or the environment and hence require
reporting in this section.
Occupational exposure limits, if available, are listed in section 8.
4. First aid measures
First aid measures
Eye contact : Check for and remove any contact lenses. In case of contact with eyes, rinse
immediately with plenty of water. Get medical attention if symptoms occur.
Skin contact : Wash with soap and water. Get medical attention if symptoms occur.
Inhalation : If inhaled, remove to fresh air. If not breathing, give artificial respiration. Get medical
attention if symptoms appear.
Ingestion : Do not induce vomiting. Never give anything by mouth to an unconscious person.
Get medical attention if symptoms appear.
Protection of first-aiders : No action shall be taken involving any personal risk or without suitable training.
Notes to physician : In case of inhalation of decomposition products in a fire, symptoms may be delayed.
The exposed person may need to be kept under medical surveillance for 48 hours.
See section 11 for more detailed information on health effects and symptoms.
5. Fire-fighting measures
Extinguishing media
Suitable : Use an extinguishing agent suitable for the surrounding fire.
Not suitable : None known.
Hazardous thermal : Decomposition products may include the following materials:
carbon dioxide
decomposition products
carbon monoxide
nitrogen oxides
sulfur oxides
Special protective : Fire-fighters should wear appropriate protective equipment and self-contained
breathing apparatus (SCBA) with a full face-piece operated in positive pressure
equipment for fire-fighters
mode.
Remark : Not available.
6. Accidental release measures
Personal precautions, : No action shall be taken involving any personal risk or without suitable training.
Evacuate surrounding areas. Keep unnecessary and unprotected personnel from
protective equipment and
entering. Do not touch or walk through spilled material. Provide adequate
emergency procedures
ventilation. Wear appropriate respirator when ventilation is inadequate. Put on
appropriate personal protective equipment (see section 8).
Environmental precautions : Avoid dispersal of spilled material and runoff and contact with soil, waterways, drains
and sewers. Inform the relevant authorities if the product has caused environmental
pollution (sewers, waterways, soil or air).
Methods and materials for containment and cleaning up
Small spill : Move containers from spill area. Vacuum or sweep up material and place in a
designated, labeled waste container. Dispose of via a licensed waste disposal
contractor.
: 01/15/2008 Page: 2/6
Date of issue
Enzyme Reagent
6. Accidental release measures
Large spill : Move containers from spill area. Approach release from upwind. Prevent entry into
sewers, water courses, basements or confined areas. Vacuum or sweep up material
and place in a designated, labeled waste container. Dispose of via a licensed waste
disposal contractor. Note: see section 1 for emergency contact information and
section 13 for waste disposal.
7. Handling and storage
Precautions for safe : Put on appropriate personal protective equipment (see section 8). Eating, drinking
and smoking should be prohibited in areas where this material is handled, stored and
handling
processed. Workers should wash hands and face before eating, drinking and
smoking. Do not ingest. Avoid contact with eyes, skin and clothing. Keep in the
original container or an approved alternative made from a compatible material, kept
tightly closed when not in use. Empty containers retain product residue and can be
hazardous. Do not reuse container.
Conditions for safe storage : Store in accordance with local regulations. Store in original container protected from
direct sunlight in a dry, cool and well-ventilated area, away from incompatible
materials (see section 10) and food and drink. Keep container tightly closed and
sealed until ready for use. Containers that have been opened must be carefully
resealed and kept upright to prevent leakage. Do not store in unlabeled containers.
Use appropriate containment to avoid environmental contamination.
8. Exposure controls/personal protection
Control parameters
Ingredient name Exposure limits
None.
Recommended monitoring : If this product contains ingredients with exposure limits, personal, workplace
atmosphere or biological monitoring may be required to determine the effectiveness
procedures
of the ventilation or other control measures and/or the necessity to use respiratory
protective equipment.
Appropriate engineering : No special ventilation requirements. Good general ventilation should be sufficient to
control worker exposure to airborne contaminants. If this product contains
controls
ingredients with exposure limits, use process enclosures, local exhaust ventilation or
other engineering controls to keep worker exposure below any recommended or
statutory limits.
Environmental exposure : Emissions from ventilation or work process equipment should be checked to ensure
they comply with the requirements of environmental protection legislation. In some
controls
cases, fume scrubbers, filters or engineering modifications to the process equipment
will be necessary to reduce emissions to acceptable levels.
Individual protection measures
Hygiene measures : Wash hands, forearms and face thoroughly after handling chemical products, before
eating, smoking and using the lavatory and at the end of the working period.
Appropriate techniques should be used to remove potentially contaminated clothing.
Wash contaminated clothing before reusing. Ensure that eyewash stations and
safety showers are close to the workstation location.
Respiratory protection : Use a properly fitted, air-purifying or supplied air respirator complying with an
approved standard if a risk assessment indicates this is necessary. Respirator
selection must be based on known or anticipated exposure levels, the hazards of the
product and the safe working limits of the selected respirator.
Hand protection : Chemical-resistant, impervious gloves complying with an approved standard should
be worn at all times when handling chemical products if a risk assessment indicates
this is necessary.
Eye protection : Safety eyewear complying with an approved standard should be used when a risk
assessment indicates this is necessary to avoid exposure to liquid splashes, mists,
gases or dusts.
: 01/15/2008 Page: 3/6
Date of issue
Enzyme Reagent
8. Exposure controls/personal protection
Skin protection : Personal protective equipment for the body should be selected based on the task
being performed and the risks involved and should be approved by a specialist
before handling this product.
9. Physical and chemical properties
Appearance
Physical state : Solid. [Lyophilized.]
Color : White to off-white.
pH : 7
Flammability (solid, gas) : Non-flammable in the presence of the following materials or conditions: open flames,
sparks and static discharge, heat, shocks and mechanical impacts, oxidizing
materials, reducing materials, combustible materials, organic materials, metals,
acids, alkalis and moisture.
10. Stability and reactivity
Chemical stability : The product is stable. Under normal conditions of storage and use, hazardous
polymerization will not occur.
Conditions to avoid : No specific data.
Incompatible materials : No specific data.
Hazardous decomposition : Under normal conditions of storage and use, hazardous decomposition products
products should not be produced.
11. Toxicological information
Most important health effects
Potential acute health effects
Inhalation : Exposure to decomposition products may cause a health hazard. Serious effects
may be delayed following exposure.
Ingestion : No known significant effects or critical hazards.
Skin contact : No known significant effects or critical hazards.
Eye contact : No known significant effects or critical hazards.
Potential chronic health effects
General : No known significant effects or critical hazards.
Inhalation : No known significant effects or critical hazards.
Ingestion : No known significant effects or critical hazards.
Skin contact : No known significant effects or critical hazards.
Eye contact : No known significant effects or critical hazards.
Carcinogenicity : No known significant effects or critical hazards.
Mutagenicity : No known significant effects or critical hazards.
Teratogenicity : No known significant effects or critical hazards.
Developmental effects : No known significant effects or critical hazards.
Fertility effects : No known significant effects or critical hazards.
Symptoms related to the physical, chemical and toxicological characteristics
Inhalation : No specific data.
Ingestion : No specific data.
Skin : No specific data.
: 01/15/2008 Page: 4/6
Date of issue
Enzyme Reagent
11. Toxicological information
Eyes : No specific data.
Other information : Not available.
12. Ecological information
Environmental effects : No known significant effects or critical hazards.
Aquatic ecotoxicity
Product/ingredient name Test Species Exposure Result
Not available.
Product/ingredient name Aquatic half-life Photolysis Biodegradability
Not available.
Bioaccumulative potential
Product/ingredient name LogPow BCF Potential
Not available.
Mobility : Not available.
Other adverse effects : No known significant effects or critical hazards.
13. Disposal considerations
Disposal methods : The generation of waste should be avoided or minimized wherever possible. Empty
containers or liners may retain some product residues. This material and its
container must be disposed of in a safe way. Dispose of surplus and non-recyclable
products via a licensed waste disposal contractor. Disposal of this product, solutions
and any by-products should at all times comply with the requirements of
environmental protection and waste disposal legislation and any regional local
authority requirements. Avoid dispersal of spilled material and runoff and contact
with soil, waterways, drains and sewers.
14. Transport information
International transport regulations
IMDG / IATA : Not regulated by any transport mode.
15. Regulatory information
Japan Control Law : Not regulated.
Chemical Substances Control Law (CSCL)
Ingredient name Classification
Triton X-100 Type III monitoring
Biodegradability : Not available.
Concentration of : Not available.
chemicals accumulated in
fish
Japan inventory (ENCS) : See Section 3.
Japan inventory (ISHL) : See Section 3.
Other regulations : Not available.
: 01/15/2008 Page: 5/6
Date of issue
Enzyme Reagent
16. Other information
History
: 01/15/2008
Date of issue
Version :1
1
References : Not available.
Notice to reader
To the best of our knowledge, the information contained herein is accurate. However, neither the above
named supplier nor any of its subsidiaries assumes any liability whatsoever for the accuracy or completeness
of the information contained herein. Final determination of suitability of any material is the sole responsibility
of the user. All materials may present unknown hazards and should be used with caution. Although certain
hazards are described herein, we cannot guarantee that these are the only hazards that exist.
: 01/15/2008 Page: 6/6
Date of issue
Standard : JIS Z7250 (Japan)
SAFETY DATA SHEET
Wash Solution
1. Product and company identification
Product name : Wash Solution
Used in : APTIMA HIV-1 RNA Qualitative Assay 302178, APTIMA HCV RNA Qualitative
Assay 302179, APTIMA CT Assay 301088, APTIMA GC Assay 301091, APTIMA
Combo 2 301032, APTIMA Assay Fluids Kit 302002C, APTIMA Assay Fluids Kit
TIGRIS 302382, PROGENSA PCA3 Assay Kit CE 302355, PCA3/PSA
Supplemental Fluids Kit 302030.
MSDS no. : 0041
Product type : Liquid.
Supplier/Manufacturer : Gen-Probe Incorporated
10210 Genetic Center Drive
San Diego, CA 92121-4362
Emergency telephone : CHEMTREC International: (703) 527-3887
number (with hours of
operation)
Recommended use of the chemical
In vitro diagnostic.
Restrictions on use
Uses Industry category Use category Use sub- Function
category category
None identified.
2. Hazards identification
Classification of the : Not regulated.
substance or mixture
GHS label elements
Hazard statements : No known significant effects or critical hazards.
Precautionary statements
Prevention : Not applicable.
Response : Not applicable.
Storage : Not applicable.
Disposal : Not applicable.
Other hazards which do not : Not available.
result in classification
Country information
Japan - Classification : Other hazardous substances.
3. Composition/information on ingredients
Substance/mixture : Mixture
Chemical name : Not applicable.
Other means of : Not applicable.
identification
CAS number/other identifiers
CAS number : Not applicable.
ENCS number : Not applicable.
ISHL number : Not applicable.
: 01/15/2008 Page: 1/6
Date of issue
Wash Solution
3. Composition/information on ingredients
Ingredient name % CAS number ENCS ISHL
None.
Due to differing non-hazardous components, the products listed in each part number in 鈥淯sed In鈥? section are
not interchangeable. See package insert for product use.
There are no ingredients present which, within the current knowledge of the supplier and in the concentrations
applicable, are classified as hazardous to health or the environment and hence require reporting in this
section.
Occupational exposure limits, if available, are listed in section 8.
4. First aid measures
First aid measures
Eye contact : Check for and remove any contact lenses. In case of contact with eyes, rinse
immediately with plenty of water. Get medical attention if symptoms occur.
Skin contact : Wash with soap and water. Get medical attention if symptoms occur.
Inhalation : If inhaled, remove to fresh air. If not breathing, give artificial respiration. Get medical
attention if symptoms appear.
Ingestion : Do not induce vomiting. Never give anything by mouth to an unconscious person.
Get medical attention if symptoms appear.
Protection of first-aiders : No action shall be taken involving any personal risk or without suitable training.
Notes to physician : No specific treatment. Treat symptomatically. Contact poison treatment specialist
immediately if large quantities have been ingested or inhaled.
See section 11 for more detailed information on health effects and symptoms.
5. Fire-fighting measures
Extinguishing media
Suitable : Use an extinguishing agent suitable for the surrounding fire.
Not suitable : None known.
Hazardous thermal : No specific data.
decomposition products
Special protective : Fire-fighters should wear appropriate protective equipment and self-contained
breathing apparatus (SCBA) with a full face-piece operated in positive pressure
equipment for fire-fighters
mode.
Remark : Not available.
6. Accidental release measures
Personal precautions, : No action shall be taken involving any personal risk or without suitable training.
Evacuate surrounding areas. Keep unnecessary and unprotected personnel from
protective equipment and
entering. Do not touch or walk through spilled material. Avoid breathing vapor or
emergency procedures
mist. Provide adequate ventilation. Wear appropriate respirator when ventilation is
inadequate. Put on appropriate personal protective equipment (see section 8).
Environmental precautions : Avoid dispersal of spilled material and runoff and contact with soil, waterways, drains
and sewers. Inform the relevant authorities if the product has caused environmental
pollution (sewers, waterways, soil or air).
Methods and materials for containment and cleaning up
Small spill : Stop leak if without risk. Move containers from spill area. Dilute with water and mop
up if water-soluble or absorb with an inert dry material and place in an appropriate
waste disposal container. Dispose of via a licensed waste disposal contractor.
: 01/15/2008 Page: 2/6
Date of issue
Wash Solution
6. Accidental release measures
Large spill : Stop leak if without risk. Move containers from spill area. Approach release from
upwind. Prevent entry into sewers, water courses, basements or confined areas.
Wash spillages into an effluent treatment plant or proceed as follows. Contain and
collect spillage with non-combustible, absorbent material e.g. sand, earth, vermiculite
or diatomaceous earth and place in container for disposal according to local
regulations (see section 13). Dispose of via a licensed waste disposal contractor.
Contaminated absorbent material may pose the same hazard as the spilled product.
Note: see section 1 for emergency contact information and section 13 for waste
disposal.
7. Handling and storage
Precautions for safe : Put on appropriate personal protective equipment (see section 8). Eating, drinking
and smoking should be prohibited in areas where this material is handled, stored and
handling
processed. Workers should wash hands and face before eating, drinking and
smoking. Do not ingest. Avoid contact with eyes, skin and clothing. Avoid breathing
vapor or mist. Keep in the original container or an approved alternative made from a
compatible material, kept tightly closed when not in use. Empty containers retain
product residue and can be hazardous. Do not reuse container.
Conditions for safe storage : Store in accordance with local regulations. Store in original container protected from
direct sunlight in a dry, cool and well-ventilated area, away from incompatible
materials (see section 10) and food and drink. Keep container tightly closed and
sealed until ready for use. Containers that have been opened must be carefully
resealed and kept upright to prevent leakage. Do not store in unlabeled containers.
Use appropriate containment to avoid environmental contamination.
8. Exposure controls/personal protection
Control parameters
Ingredient name Exposure limits
None.
Recommended monitoring : If this product contains ingredients with exposure limits, personal, workplace
atmosphere or biological monitoring may be required to determine the effectiveness
procedures
of the ventilation or other control measures and/or the necessity to use respiratory
protective equipment.
Appropriate engineering : No special ventilation requirements. Good general ventilation should be sufficient to
control worker exposure to airborne contaminants. If this product contains
controls
ingredients with exposure limits, use process enclosures, local exhaust ventilation or
other engineering controls to keep worker exposure below any recommended or
statutory limits.
Environmental exposure : Emissions from ventilation or work process equipment should be checked to ensure
they comply with the requirements of environmental protection legislation. In some
controls
cases, fume scrubbers, filters or engineering modifications to the process equipment
will be necessary to reduce emissions to acceptable levels.
Individual protection measures
Hygiene measures : Wash hands, forearms and face thoroughly after handling chemical products, before
eating, smoking and using the lavatory and at the end of the working period.
Appropriate techniques should be used to remove potentially contaminated clothing.
Wash contaminated clothing before reusing. Ensure that eyewash stations and
safety showers are close to the workstation location.
Respiratory protection : Use a properly fitted, air-purifying or supplied air respirator complying with an
approved standard if a risk assessment indicates this is necessary. Respirator
selection must be based on known or anticipated exposure levels, the hazards of the
product and the safe working limits of the selected respirator.
Hand protection : Chemical-resistant, impervious gloves complying with an approved standard should
be worn at all times when handling chemical products if a risk assessment indicates
this is necessary.
: 01/15/2008 Page: 3/6
Date of issue
Wash Solution
8. Exposure controls/personal protection
Eye protection : Safety eyewear complying with an approved standard should be used when a risk
assessment indicates this is necessary to avoid exposure to liquid splashes, mists,
gases or dusts.
Skin protection : Personal protective equipment for the body should be selected based on the task
being performed and the risks involved and should be approved by a specialist
before handling this product.
9. Physical and chemical properties
Appearance
Physical state : Liquid. [Clear.]
Color : Colorless.
pH : ~ 7.5.
Flammability (solid, gas) : Non-flammable in the presence of the following materials or conditions: open flames,
sparks and static discharge, heat, shocks and mechanical impacts, oxidizing
materials, reducing materials, combustible materials, organic materials, metals,
acids, alkalis and moisture.
10. Stability and reactivity
Chemical stability : The product is stable. Under normal conditions of storage and use, hazardous
polymerization will not occur.
Conditions to avoid : No specific data.
Incompatible materials : No specific data.
Hazardous decomposition : Under normal conditions of storage and use, hazardous decomposition products
products should not be produced.
11. Toxicological information
Most important health effects
Potential acute health effects
Inhalation : No known significant effects or critical hazards.
Ingestion : No known significant effects or critical hazards.
Skin contact : No known significant effects or critical hazards.
Eye contact : No known significant effects or critical hazards.
Potential chronic health effects
General : No known significant effects or critical hazards.
Inhalation : No known significant effects or critical hazards.
Ingestion : No known significant effects or critical hazards.
Skin contact : No known significant effects or critical hazards.
Eye contact : No known significant effects or critical hazards.
Carcinogenicity : No known significant effects or critical hazards.
Mutagenicity : No known significant effects or critical hazards.
Teratogenicity : No known significant effects or critical hazards.
Developmental effects : No known significant effects or critical hazards.
Fertility effects : No known significant effects or critical hazards.
Symptoms related to the physical, chemical and toxicological characteristics
Inhalation : No specific data.
: 01/15/2008 Page: 4/6
Date of issue
Wash Solution
11. Toxicological information
Ingestion : No specific data.
Skin : No specific data.
Eyes : No specific data.
Other information : Not available.
12. Ecological information
Environmental effects : No known significant effects or critical hazards.
Aquatic ecotoxicity
Product/ingredient name Test Species Exposure Result
Not available.
Product/ingredient name Aquatic half-life Photolysis Biodegradability
Not available.
Bioaccumulative potential
Product/ingredient name LogPow BCF Potential
Not available.
Mobility : Not available.
Other adverse effects : No known significant effects or critical hazards.
13. Disposal considerations
Disposal methods : The generation of waste should be avoided or minimized wherever possible. Empty
containers or liners may retain some product residues. This material and its
container must be disposed of in a safe way. Dispose of surplus and non-recyclable
products via a licensed waste disposal contractor. Disposal of this product, solutions
and any by-products should at all times comply with the requirements of
environmental protection and waste disposal legislation and any regional local
authority requirements. Avoid dispersal of spilled material and runoff and contact
with soil, waterways, drains and sewers.
14. Transport information
International transport regulations
IMDG / IATA : Not regulated by any transport mode.
15. Regulatory information
Japan Control Law : Not regulated.
Chemical Substances Control Law (CSCL)
Ingredient name Classification
Ethylenediamine tetraacetic acid Type II monitoring
Biodegradability : Not available.
Concentration of : Not available.
chemicals accumulated in
fish
Japan inventory (ENCS) : See Section 3.
Japan inventory (ISHL) : See Section 3.
Other regulations : Not available.
: 01/15/2008 Page: 5/6
Date of issue
Wash Solution
16. Other information
History
: 01/15/2008
Date of issue
Version :1
0
References : Not available.
Notice to reader
To the best of our knowledge, the information contained herein is accurate. However, neither the above
named supplier nor any of its subsidiaries assumes any liability whatsoever for the accuracy or completeness
of the information contained herein. Final determination of suitability of any material is the sole responsibility
of the user. All materials may present unknown hazards and should be used with caution. Although certain
hazards are described herein, we cannot guarantee that these are the only hazards that exist.
: 01/15/2008 Page: 6/6
Date of issue
Standard : JIS Z7250 (Japan)
SAFETY DATA SHEET
Oil Reagent
1. Product and company identification
Product name : Oil Reagent
Used in : APTIMA HIV-1 RNA Qualitative Assay 302178, APTIMA HCV RNA Qualitative
Assay 302179, APTIMA CT Assay 301088, APTIMA GC Assay 301091, APTIMA
Combo 2 301032, APTIMA Assay Fluids Kit 302002C, APTIMA Assay Fluids Kit
TIGRIS 302382, PROGENSA PCA3 Assay Kit CE 302355, PCA3/PSA
Supplemental Fluids Kit 302030.
MSDS no. : 0042
Product type : Liquid.
Supplier/Manufacturer : Gen-Probe Incorporated
10210 Genetic Center Drive
San Diego, CA 92121-4362
Emergency telephone : CHEMTREC International: (703) 527-3887
number (with hours of
operation)
Recommended use of the chemical
In vitro diagnostic.
Restrictions on use
Uses Industry category Use category Use sub- Function
category category
None identified.
2. Hazards identification
Classification of the : Not regulated.
substance or mixture
GHS label elements
Hazard statements : No known significant effects or critical hazards.
Precautionary statements
Prevention : Not applicable.
Response : Not applicable.
Storage : Not applicable.
Disposal : Not applicable.
Other hazards which do not : Not available.
result in classification
Country information
Japan - Classification : Not applicable.
3. Composition/information on ingredients
Substance/mixture : Mono-constituent substance
Chemical name : Not applicable.
Other means of : Not applicable.
identification
CAS number/other identifiers
CAS number : Not applicable.
ENCS number : Not applicable.
ISHL number : Not applicable.
: 01/15/2008 Page: 1/6
Date of issue
Oil Reagent
3. Composition/information on ingredients
Ingredient name % CAS number ENCS ISHL
None.
Due to differing non-hazardous components, the products listed in each part number in 鈥淯sed In鈥? section are
not interchangeable. See package insert for product use.
There are no ingredients present which, within the current knowledge of the supplier and in the concentrations
applicable, are classified as hazardous to health or the environment and hence require reporting in this
section.
Occupational exposure limits, if available, are listed in section 8.
4. First aid measures
First aid measures
Eye contact : Check for and remove any contact lenses. In case of contact with eyes, rinse
immediately with plenty of water. Get medical attention if symptoms occur.
Skin contact : Wash with soap and water. Get medical attention if symptoms occur.
Inhalation : If inhaled, remove to fresh air. If not breathing, give artificial respiration. Get medical
attention if symptoms appear.
Ingestion : Do not induce vomiting. Never give anything by mouth to an unconscious person.
Get medical attention if symptoms appear.
Protection of first-aiders : No action shall be taken involving any personal risk or without suitable training.
Notes to physician : No specific treatment. Treat symptomatically. Contact poison treatment specialist
immediately if large quantities have been ingested or inhaled.
See section 11 for more detailed information on health effects and symptoms.
5. Fire-fighting measures
Extinguishing media
Suitable : Use an extinguishing agent suitable for the surrounding fire.
Not suitable : None known.
Hazardous thermal : No specific data.
decomposition products
Special protective : Fire-fighters should wear appropriate protective equipment and self-contained
breathing apparatus (SCBA) with a full face-piece operated in positive pressure
equipment for fire-fighters
mode.
Remark : Not available.
6. Accidental release measures
Personal precautions, : No action shall be taken involving any personal risk or without suitable training.
Evacuate surrounding areas. Keep unnecessary and unprotected personnel from
protective equipment and
entering. Do not touch or walk through spilled material. Avoid breathing vapor or
emergency procedures
mist. Provide adequate ventilation. Wear appropriate respirator when ventilation is
inadequate. Put on appropriate personal protective equipment (see section 8).
Environmental precautions : Avoid dispersal of spilled material and runoff and contact with soil, waterways, drains
and sewers. Inform the relevant authorities if the product has caused environmental
pollution (sewers, waterways, soil or air).
Methods and materials for containment and cleaning up
Small spill : Stop leak if without risk. Move containers from spill area. Dilute with water and mop
up if water-soluble or absorb with an inert dry material and place in an appropriate
waste disposal container. Dispose of via a licensed waste disposal contractor.
: 01/15/2008 Page: 2/6
Date of issue
Oil Reagent
6. Accidental release measures
Large spill : Stop leak if without risk. Move containers from spill area. Approach release from
upwind. Prevent entry into sewers, water courses, basements or confined areas.
Wash spillages into an effluent treatment plant or proceed as follows. Contain and
collect spillage with non-combustible, absorbent material e.g. sand, earth, vermiculite
or diatomaceous earth and place in container for disposal according to local
regulations (see section 13). Dispose of via a licensed waste disposal contractor.
Contaminated absorbent material may pose the same hazard as the spilled product.
Note: see section 1 for emergency contact information and section 13 for waste
disposal.
7. Handling and storage
Precautions for safe : Put on appropriate personal protective equipment (see section 8). Eating, drinking
and smoking should be prohibited in areas where this material is handled, stored and
handling
processed. Workers should wash hands and face before eating, drinking and
smoking. Do not ingest. Avoid contact with eyes, skin and clothing. Avoid breathing
vapor or mist. Keep in the original container or an approved alternative made from a
compatible material, kept tightly closed when not in use. Empty containers retain
product residue and can be hazardous. Do not reuse container.
Conditions for safe storage : Store in accordance with local regulations. Store in original container protected from
direct sunlight in a dry, cool and well-ventilated area, away from incompatible
materials (see section 10) and food and drink. Keep container tightly closed and
sealed until ready for use. Containers that have been opened must be carefully
resealed and kept upright to prevent leakage. Do not store in unlabeled containers.
Use appropriate containment to avoid environmental contamination.
8. Exposure controls/personal protection
Control parameters
Ingredient name Exposure limits
None.
Recommended monitoring : If this product contains ingredients with exposure limits, personal, workplace
atmosphere or biological monitoring may be required to determine the effectiveness
procedures
of the ventilation or other control measures and/or the necessity to use respiratory
protective equipment.
Appropriate engineering : No special ventilation requirements. Good general ventilation should be sufficient to
control worker exposure to airborne contaminants. If this product contains
controls
ingredients with exposure limits, use process enclosures, local exhaust ventilation or
other engineering controls to keep worker exposure below any recommended or
statutory limits.
Environmental exposure : Emissions from ventilation or work process equipment should be checked to ensure
they comply with the requirements of environmental protection legislation. In some
controls
cases, fume scrubbers, filters or engineering modifications to the process equipment
will be necessary to reduce emissions to acceptable levels.
Individual protection measures
Hygiene measures : Wash hands, forearms and face thoroughly after handling chemical products, before
eating, smoking and using the lavatory and at the end of the working period.
Appropriate techniques should be used to remove potentially contaminated clothing.
Wash contaminated clothing before reusing. Ensure that eyewash stations and
safety showers are close to the workstation location.
Respiratory protection : Use a properly fitted, air-purifying or supplied air respirator complying with an
approved standard if a risk assessment indicates this is necessary. Respirator
selection must be based on known or anticipated exposure levels, the hazards of the
product and the safe working limits of the selected respirator.
Hand protection : Chemical-resistant, impervious gloves complying with an approved standard should
be worn at all times when handling chemical products if a risk assessment indicates
this is necessary.
: 01/15/2008 Page: 3/6
Date of issue
Oil Reagent
8. Exposure controls/personal protection
Eye protection : Safety eyewear complying with an approved standard should be used when a risk
assessment indicates this is necessary to avoid exposure to liquid splashes, mists,
gases or dusts.
Skin protection : Personal protective equipment for the body should be selected based on the task
being performed and the risks involved and should be approved by a specialist
before handling this product.
9. Physical and chemical properties
Appearance
Physical state : Liquid. [Clear.]
Color : Colorless.
pH : Not available.
Flammability (solid, gas) : Non-flammable in the presence of the following materials or conditions: open flames,
sparks and static discharge, heat, shocks and mechanical impacts, oxidizing
materials, reducing materials, combustible materials, organic materials, metals,
acids, alkalis and moisture.
10. Stability and reactivity
Chemical stability : The product is stable. Under normal conditions of storage and use, hazardous
polymerization will not occur.
Conditions to avoid : No specific data.
Incompatible materials : No specific data.
Hazardous decomposition : Under normal conditions of storage and use, hazardous decomposition products
products should not be produced.
11. Toxicological information
Most important health effects
Potential acute health effects
Inhalation : No known significant effects or critical hazards.
Ingestion : No known significant effects or critical hazards.
Skin contact : No known significant effects or critical hazards.
Eye contact : No known significant effects or critical hazards.
Potential chronic health effects
General : No known significant effects or critical hazards.
Inhalation : No known significant effects or critical hazards.
Ingestion : No known significant effects or critical hazards.
Skin contact : No known significant effects or critical hazards.
Eye contact : No known significant effects or critical hazards.
Carcinogenicity : No known significant effects or critical hazards.
Mutagenicity : No known significant effects or critical hazards.
Teratogenicity : No known significant effects or critical hazards.
Developmental effects : No known significant effects or critical hazards.
Fertility effects : No known significant effects or critical hazards.
Symptoms related to the physical, chemical and toxicological characteristics
Inhalation : No specific data.
: 01/15/2008 Page: 4/6
Date of issue
Oil Reagent
11. Toxicological information
Ingestion : No specific data.
Skin : No specific data.
Eyes : No specific data.
Other information : Not available.
12. Ecological information
Environmental effects : No known significant effects or critical hazards.
Aquatic ecotoxicity
Product/ingredient name Test Species Exposure Result
Not available.
Product/ingredient name Aquatic half-life Photolysis Biodegradability
Not available.
Bioaccumulative potential
Product/ingredient name LogPow BCF Potential
Not available.
Mobility : Not available.
Other adverse effects : No known significant effects or critical hazards.
13. Disposal considerations
Disposal methods : The generation of waste should be avoided or minimized wherever possible. Empty
containers or liners may retain some product residues. This material and its
container must be disposed of in a safe way. Dispose of surplus and non-recyclable
products via a licensed waste disposal contractor. Disposal of this product, solutions
and any by-products should at all times comply with the requirements of
environmental protection and waste disposal legislation and any regional local
authority requirements. Avoid dispersal of spilled material and runoff and contact
with soil, waterways, drains and sewers.
14. Transport information
International transport regulations
IMDG / IATA : Not regulated by any transport mode.
15. Regulatory information
Japan Control Law : Not regulated.
Chemical Substances Control Law (CSCL)
Ingredient name Classification
Biodegradability : Not available.
Concentration of : Not available.
chemicals accumulated in
fish
Japan inventory (ENCS) : See Section 3.
Japan inventory (ISHL) : See Section 3.
Other regulations : Not available.
: 01/15/2008 Page: 5/6
Date of issue
Oil Reagent
16. Other information
History
: 01/15/2008
Date of issue
Version :1
0
References : Not available.
Notice to reader
To the best of our knowledge, the information contained herein is accurate. However, neither the above
named supplier nor any of its subsidiaries assumes any liability whatsoever for the accuracy or completeness
of the information contained herein. Final determination of suitability of any material is the sole responsibility
of the user. All materials may present unknown hazards and should be used with caution. Although certain
hazards are described herein, we cannot guarantee that these are the only hazards that exist.
: 01/15/2008 Page: 6/6
Date of issue
Standard : JIS Z7250 (Japan)
SAFETY DATA SHEET
Buffer for Deactivation Fluid
1. Product and company identification
Product name : Buffer for Deactivation Fluid
Used in : APTIMA HIV-1 RNA Qualitative Assay 302178, APTIMA HCV RNA Qualitative
Assay 302179, APTIMA CT Assay 301088, APTIMA GC Assay 301091, APTIMA
Combo 2 301032, APTIMA Assay Fluids Kit 302002C, APTIMA Assay Fluids Kit
TIGRIS 302382, PROGENSA PCA3 Assay Kit CE 302355, PCA3/PSA
Supplemental Fluids Kit 302030.
MSDS no. : 0043
Product type : Liquid.
Supplier/Manufacturer : Gen-Probe Incorporated
10210 Genetic Center Drive
San Diego, CA 92121-4362
Emergency telephone : CHEMTREC International: (703) 527-3887
number (with hours of
operation)
Recommended use of the chemical
In vitro diagnostic.
Restrictions on use
Uses Industry category Use category Use sub- Function
category category
None identified.
2. Hazards identification
Classification of the : Not regulated.
substance or mixture
GHS label elements
Hazard statements : No known significant effects or critical hazards.
Precautionary statements
Prevention : Not applicable.
Response : Not applicable.
Storage : Not applicable.
Disposal : Not applicable.
Other hazards which do not : Not available.
result in classification
Country information
Japan - Classification : Not applicable.
3. Composition/information on ingredients
Substance/mixture : Mixture
Chemical name : Not applicable.
Other means of : Not applicable.
identification
CAS number/other identifiers
CAS number : Not applicable.
ENCS number : Not applicable.
ISHL number : Not applicable.
: 01/15/2008 Page: 1/6
Date of issue
Buffer for Deactivation Fluid
3. Composition/information on ingredients
Ingredient name % CAS number ENCS ISHL
Sodium bicarbonate 5 - 10 144-55-8 (1)-14x; (1)-164 Not applicable.
Due to differing non-hazardous components, the products listed in each part number in 鈥淯sed In鈥? section are
not interchangeable. See package insert for product use.
There are no ingredients present which, within the current knowledge of the supplier and in the concentrations
applicable, are classified as hazardous to health or the environment and hence require reporting in this
section.
Occupational exposure limits, if available, are listed in section 8.
4. First aid measures
First aid measures
Eye contact : Check for and remove any contact lenses. In case of contact with eyes, rinse
immediately with plenty of water. Get medical attention if symptoms occur.
Skin contact : Wash with soap and water. Get medical attention if symptoms occur.
Inhalation : If inhaled, remove to fresh air. If not breathing, give artificial respiration. Get medical
attention if symptoms appear.
Ingestion : Do not induce vomiting. Never give anything by mouth to an unconscious person.
Get medical attention if symptoms appear.
Protection of first-aiders : No action shall be taken involving any personal risk or without suitable training.
Notes to physician : No specific treatment. Treat symptomatically. Contact poison treatment specialist
immediately if large quantities have been ingested or inhaled.
See section 11 for more detailed information on health effects and symptoms.
5. Fire-fighting measures
Extinguishing media
Suitable : Use an extinguishing agent suitable for the surrounding fire.
Not suitable : None known.
Hazardous thermal : Decomposition products may include the following materials:
carbon dioxide
decomposition products
carbon monoxide
metal oxide/oxides
Special protective : Fire-fighters should wear appropriate protective equipment and self-contained
breathing apparatus (SCBA) with a full face-piece operated in positive pressure
equipment for fire-fighters
mode.
Remark : Not available.
6. Accidental release measures
Personal precautions, : No action shall be taken involving any personal risk or without suitable training.
Evacuate surrounding areas. Keep unnecessary and unprotected personnel from
protective equipment and
entering. Do not touch or walk through spilled material. Avoid breathing vapor or
emergency procedures
mist. Provide adequate ventilation. Wear appropriate respirator when ventilation is
inadequate. Put on appropriate personal protective equipment (see section 8).
Environmental precautions : Avoid dispersal of spilled material and runoff and contact with soil, waterways, drains
and sewers. Inform the relevant authorities if the product has caused environmental
pollution (sewers, waterways, soil or air).
Methods and materials for containment and cleaning up
Small spill : Stop leak if without risk. Move containers from spill area. Dilute with water and mop
up if water-soluble or absorb with an inert dry material and place in an appropriate
waste disposal container. Dispose of via a licensed waste disposal contractor.
: 01/15/2008 Page: 2/6
Date of issue
Buffer for Deactivation Fluid
6. Accidental release measures
Large spill : Stop leak if without risk. Move containers from spill area. Approach release from
upwind. Prevent entry into sewers, water courses, basements or confined areas.
Wash spillages into an effluent treatment plant or proceed as follows. Contain and
collect spillage with non-combustible, absorbent material e.g. sand, earth, vermiculite
or diatomaceous earth and place in container for disposal according to local
regulations (see section 13). Dispose of via a licensed waste disposal contractor.
Contaminated absorbent material may pose the same hazard as the spilled product.
Note: see section 1 for emergency contact information and section 13 for waste
disposal.
7. Handling and storage
Precautions for safe : Put on appropriate personal protective equipment (see section 8). Eating, drinking
and smoking should be prohibited in areas where this material is handled, stored and
handling
processed. Workers should wash hands and face before eating, drinking and
smoking. Do not ingest. Avoid contact with eyes, skin and clothing. Avoid breathing
vapor or mist. Keep in the original container or an approved alternative made from a
compatible material, kept tightly closed when not in use. Empty containers retain
product residue and can be hazardous. Do not reuse container.
Conditions for safe storage : Store in accordance with local regulations. Store in original container protected from
direct sunlight in a dry, cool and well-ventilated area, away from incompatible
materials (see section 10) and food and drink. Keep container tightly closed and
sealed until ready for use. Containers that have been opened must be carefully
resealed and kept upright to prevent leakage. Do not store in unlabeled containers.
Use appropriate containment to avoid environmental contamination.
8. Exposure controls/personal protection
Control parameters
Ingredient name Exposure limits
None.
Recommended monitoring : If this product contains ingredients with exposure limits, personal, workplace
atmosphere or biological monitoring may be required to determine the effectiveness
procedures
of the ventilation or other control measures and/or the necessity to use respiratory
protective equipment.
Appropriate engineering : No special ventilation requirements. Good general ventilation should be sufficient to
control worker exposure to airborne contaminants. If this product contains
controls
ingredients with exposure limits, use process enclosures, local exhaust ventilation or
other engineering controls to keep worker exposure below any recommended or
statutory limits.
Environmental exposure : Emissions from ventilation or work process equipment should be checked to ensure
they comply with the requirements of environmental protection legislation. In some
controls
cases, fume scrubbers, filters or engineering modifications to the process equipment
will be necessary to reduce emissions to acceptable levels.
Individual protection measures
Hygiene measures : Wash hands, forearms and face thoroughly after handling chemical products, before
eating, smoking and using the lavatory and at the end of the working period.
Appropriate techniques should be used to remove potentially contaminated clothing.
Wash contaminated clothing before reusing. Ensure that eyewash stations and
safety showers are close to the workstation location.
Respiratory protection : Use a properly fitted, air-purifying or supplied air respirator complying with an
approved standard if a risk assessment indicates this is necessary. Respirator
selection must be based on known or anticipated exposure levels, the hazards of the
product and the safe working limits of the selected respirator.
Hand protection : Chemical-resistant, impervious gloves complying with an approved standard should
be worn at all times when handling chemical products if a risk assessment indicates
this is necessary.
: 01/15/2008 Page: 3/6
Date of issue
Buffer for Deactivation Fluid
8. Exposure controls/personal protection
Eye protection : Safety eyewear complying with an approved standard should be used when a risk
assessment indicates this is necessary to avoid exposure to liquid splashes, mists,
gases or dusts.
Skin protection : Personal protective equipment for the body should be selected based on the task
being performed and the risks involved and should be approved by a specialist
before handling this product.
9. Physical and chemical properties
Appearance
Physical state : Liquid. [Clear.]
Color : Colorless.
pH : ~ 9.3.
Flammability (solid, gas) : Non-flammable in the presence of the following materials or conditions: open flames,
sparks and static discharge, heat, shocks and mechanical impacts, oxidizing
materials, reducing materials, combustible materials, organic materials, metals,
acids, alkalis and moisture.
10. Stability and reactivity
Chemical stability : The product is stable. Under normal conditions of storage and use, hazardous
polymerization will not occur.
Conditions to avoid : No specific data.
Incompatible materials : No specific data.
Hazardous decomposition : Under normal conditions of storage and use, hazardous decomposition products
products should not be produced.
11. Toxicological information
Most important health effects
Potential acute health effects
Inhalation : No known significant effects or critical hazards.
Ingestion : No known significant effects or critical hazards.
Skin contact : No known significant effects or critical hazards.
Eye contact : No known significant effects or critical hazards.
Potential chronic health effects
General : No known significant effects or critical hazards.
Inhalation : No known significant effects or critical hazards.
Ingestion : No known significant effects or critical hazards.
Skin contact : No known significant effects or critical hazards.
Eye contact : No known significant effects or critical hazards.
Carcinogenicity : No known significant effects or critical hazards.
Mutagenicity : No known significant effects or critical hazards.
Teratogenicity : No known significant effects or critical hazards.
Developmental effects : No known significant effects or critical hazards.
Fertility effects : No known significant effects or critical hazards.
Symptoms related to the physical, chemical and toxicological characteristics
Inhalation : No specific data.
: 01/15/2008 Page: 4/6
Date of issue
Buffer for Deactivation Fluid
11. Toxicological information
Ingestion : No specific data.
Skin : No specific data.
Eyes : No specific data.
Other information : Not available.
12. Ecological information
Environmental effects : No known significant effects or critical hazards.
Aquatic ecotoxicity
Product/ingredient name Test Species Exposure Result
Sodium bicarbonate Mortality Fish 96 hours Acute LC50 9000 mg/L
Mortality Fish 96 hours Acute LC50 8600 mg/L
Mortality Fish 96 hours Acute LC50 8250 mg/L
Product/ingredient name Aquatic half-life Photolysis Biodegradability
Not available.
Bioaccumulative potential
Product/ingredient name LogPow BCF Potential
Not available.
Mobility : Not available.
Other adverse effects : No known significant effects or critical hazards.
13. Disposal considerations
Disposal methods : The generation of waste should be avoided or minimized wherever possible. Empty
containers or liners may retain some product residues. This material and its
container must be disposed of in a safe way. Dispose of surplus and non-recyclable
products via a licensed waste disposal contractor. Disposal of this product, solutions
and any by-products should at all times comply with the requirements of
environmental protection and waste disposal legislation and any regional local
authority requirements. Avoid dispersal of spilled material and runoff and contact
with soil, waterways, drains and sewers.
14. Transport information
International transport regulations
IMDG / IATA : Not regulated by any transport mode.
15. Regulatory information
Japan Control Law : Not regulated.
Chemical Substances Control Law (CSCL)
Ingredient name Classification
Biodegradability : Not available.
Concentration of : Not available.
chemicals accumulated in
fish
Japan inventory (ENCS) : See Section 3.
Japan inventory (ISHL) : See Section 3.
Other regulations : Not available.
: 01/15/2008 Page: 5/6
Date of issue
Buffer for Deactivation Fluid
16. Other information
History
: 01/15/2008
Date of issue
Version :1
0
References : Not available.
Notice to reader
To the best of our knowledge, the information contained herein is accurate. However, neither the above
named supplier nor any of its subsidiaries assumes any liability whatsoever for the accuracy or completeness
of the information contained herein. Final determination of suitability of any material is the sole responsibility
of the user. All materials may present unknown hazards and should be used with caution. Although certain
hazards are described herein, we cannot guarantee that these are the only hazards that exist.
: 01/15/2008 Page: 6/6
Date of issue
Standard : JIS Z7250 (Japan)
SAFETY DATA SHEET
Calibrators
1. Product and company identification
Product name : Calibrators
Used in : PROGENSA PCA3 Assay Kit 302355; PROGENSA PCA3 Calibrators and Controls
Kit 302353; PROGENSA PSA Calibrators and Controls Kit 302356.
MSDS no. : 0055
Product type : Liquid.
Supplier/Manufacturer : Gen-Probe Incorporated
10210 Genetic Center Drive
San Diego, CA 92121-4362
Emergency telephone : CHEMTREC International: (703) 527-3887
number (with hours of
operation)
Recommended use of the chemical
In vitro diagnostic.
Restrictions on use
Uses Industry category Use category Use sub- Function
category category
None identified.
2. Hazards identification
Classification of the : Not regulated.
substance or mixture
GHS label elements
Hazard statements : No known significant effects or critical hazards.
Precautionary statements
Prevention : Not applicable.
Response : Not applicable.
Storage : Not applicable.
Disposal : Not applicable.
Other hazards which do not : Not available.
result in classification
Country information
Japan - Classification : Not applicable.
3. Composition/information on ingredients
Substance/mixture : Mixture
Chemical name : Not applicable.
Other means of : Not applicable.
identification
CAS number/other identifiers
CAS number : Not applicable.
ENCS number : Not applicable.
ISHL number : Not applicable.
Ingredient name % CAS number ENCS ISHL
None.
: 01/15/2008 Page: 1/6
Date of issue
Calibrators
3. Composition/information on ingredients
Due to differing non-hazardous components, the products listed in each part number in 鈥淯sed In鈥? section are
not interchangeable. See package insert for product use.
There are no ingredients present which, within the current knowledge of the supplier and in the concentrations
applicable, are classified as hazardous to health or the environment and hence require reporting in this
section.
Occupational exposure limits, if available, are listed in section 8.
4. First aid measures
First aid measures
Eye contact : Check for and remove any contact lenses. In case of contact with eyes, rinse
immediately with plenty of water. Get medical attention if symptoms occur.
Skin contact : Wash with soap and water. Get medical attention if symptoms occur.
Inhalation : If inhaled, remove to fresh air. If not breathing, give artificial respiration. Get medical
attention if symptoms appear.
Ingestion : Do not induce vomiting. Never give anything by mouth to an unconscious person.
Get medical attention if symptoms appear.
Protection of first-aiders : No action shall be taken involving any personal risk or without suitable training.
Notes to physician : No specific treatment. Treat symptomatically. Contact poison treatment specialist
immediately if large quantities have been ingested or inhaled.
See section 11 for more detailed information on health effects and symptoms.
5. Fire-fighting measures
Extinguishing media
Suitable : Use an extinguishing agent suitable for the surrounding fire.
Not suitable : None known.
Hazardous thermal : Decomposition products may include the following materials:
carbon dioxide
decomposition products
carbon monoxide
sulfur oxides
metal oxide/oxides
Special protective : Fire-fighters should wear appropriate protective equipment and self-contained
breathing apparatus (SCBA) with a full face-piece operated in positive pressure
equipment for fire-fighters
mode.
Remark : Not available.
6. Accidental release measures
Personal precautions, : No action shall be taken involving any personal risk or without suitable training.
Evacuate surrounding areas. Keep unnecessary and unprotected personnel from
protective equipment and
entering. Do not touch or walk through spilled material. Avoid breathing vapor or
emergency procedures
mist. Provide adequate ventilation. Wear appropriate respirator when ventilation is
inadequate. Put on appropriate personal protective equipment (see section 8).
Environmental precautions : Avoid dispersal of spilled material and runoff and contact with soil, waterways, drains
and sewers. Inform the relevant authorities if the product has caused environmental
pollution (sewers, waterways, soil or air).
Methods and materials for containment and cleaning up
Small spill : Stop leak if without risk. Move containers from spill area. Dilute with water and mop
up if water-soluble or absorb with an inert dry material and place in an appropriate
waste disposal container. Dispose of via a licensed waste disposal contractor.
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6. Accidental release measures
Large spill : Stop leak if without risk. Move containers from spill area. Approach release from
upwind. Prevent entry into sewers, water courses, basements or confined areas.
Wash spillages into an effluent treatment plant or proceed as follows. Contain and
collect spillage with non-combustible, absorbent material e.g. sand, earth, vermiculite
or diatomaceous earth and place in container for disposal according to local
regulations (see section 13). Dispose of via a licensed waste disposal contractor.
Contaminated absorbent material may pose the same hazard as the spilled product.
Note: see section 1 for emergency contact information and section 13 for waste
disposal.
7. Handling and storage
Precautions for safe : Put on appropriate personal protective equipment (see section 8). Eating, drinking
and smoking should be prohibited in areas where this material is handled, stored and
handling
processed. Workers should wash hands and face before eating, drinking and
smoking. Do not ingest. Avoid contact with eyes, skin and clothing. Avoid breathing
vapor or mist. Keep in the original container or an approved alternative made from a
compatible material, kept tightly closed when not in use. Empty containers retain
product residue and can be hazardous. Do not reuse container.
Conditions for safe storage : Store in accordance with local regulations. Store in original container protected from
direct sunlight in a dry, cool and well-ventilated area, away from incompatible
materials (see section 10) and food and drink. Keep container tightly closed and
sealed until ready for use. Containers that have been opened must be carefully
resealed and kept upright to prevent leakage. Do not store in unlabeled containers.
Use appropriate containment to avoid environmental contamination.
8. Exposure controls/personal protection
Control parameters
Ingredient name Exposure limits
None.
Recommended monitoring : If this product contains ingredients with exposure limits, personal, workplace
atmosphere or biological monitoring may be required to determine the effectiveness
procedures
of the ventilation or other control measures and/or the necessity to use respiratory
protective equipment.
Appropriate engineering : No special ventilation requirements. Good general ventilation should be sufficient to
control worker exposure to airborne contaminants. If this product contains
controls
ingredients with exposure limits, use process enclosures, local exhaust ventilation or
other engineering controls to keep worker exposure below any recommended or
statutory limits.
Environmental exposure : Emissions from ventilation or work process equipment should be checked to ensure
they comply with the requirements of environmental protection legislation. In some
controls
cases, fume scrubbers, filters or engineering modifications to the process equipment
will be necessary to reduce emissions to acceptable levels.
Individual protection measures
Hygiene measures : Wash hands, forearms and face thoroughly after handling chemical products, before
eating, smoking and using the lavatory and at the end of the working period.
Appropriate techniques should be used to remove potentially contaminated clothing.
Wash contaminated clothing before reusing. Ensure that eyewash stations and
safety showers are close to the workstation location.
Respiratory protection : Use a properly fitted, air-purifying or supplied air respirator complying with an
approved standard if a risk assessment indicates this is necessary. Respirator
selection must be based on known or anticipated exposure levels, the hazards of the
product and the safe working limits of the selected respirator.
Hand protection : Chemical-resistant, impervious gloves complying with an approved standard should
be worn at all times when handling chemical products if a risk assessment indicates
this is necessary.
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8. Exposure controls/personal protection
Eye protection : Safety eyewear complying with an approved standard should be used when a risk
assessment indicates this is necessary to avoid exposure to liquid splashes, mists,
gases or dusts.
Skin protection : Personal protective equipment for the body should be selected based on the task
being performed and the risks involved and should be approved by a specialist
before handling this product.
9. Physical and chemical properties
Appearance
Physical state : Liquid.
Color : Colorless.
pH : ~ 6.7.
Flammability (solid, gas) : Non-flammable in the presence of the following materials or conditions: open flames,
sparks and static discharge, heat, shocks and mechanical impacts, oxidizing
materials, reducing materials, combustible materials, organic materials, metals,
acids, alkalis and moisture.
10. Stability and reactivity
Chemical stability : The product is stable. Under normal conditions of storage and use, hazardous
polymerization will not occur.
Conditions to avoid : No specific data.
Incompatible materials : No specific data.
Hazardous decomposition : Under normal conditions of storage and use, hazardous decomposition products
products should not be produced.
11. Toxicological information
Most important health effects
Potential acute health effects
Inhalation : No known significant effects or critical hazards.
Ingestion : No known significant effects or critical hazards.
Skin contact : No known significant effects or critical hazards.
Eye contact : No known significant effects or critical hazards.
Potential chronic health effects
General : No known significant effects or critical hazards.
Inhalation : No known significant effects or critical hazards.
Ingestion : No known significant effects or critical hazards.
Skin contact : No known significant effects or critical hazards.
Eye contact : No known significant effects or critical hazards.
Carcinogenicity : No known significant effects or critical hazards.
Mutagenicity : No known significant effects or critical hazards.
Teratogenicity : No known significant effects or critical hazards.
Developmental effects : No known significant effects or critical hazards.
Fertility effects : No known significant effects or critical hazards.
Symptoms related to the physical, chemical and toxicological characteristics
Inhalation : No specific data.
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11. Toxicological information
Ingestion : No specific data.
Skin : No specific data.
Eyes : No specific data.
Other information : Not available.
12. Ecological information
Environmental effects : No known significant effects or critical hazards.
Aquatic ecotoxicity
Product/ingredient name Test Species Exposure Result
Not available.
Product/ingredient name Aquatic half-life Photolysis Biodegradability
Not available.
Bioaccumulative potential
Product/ingredient name LogPow BCF Potential
Not available.
Mobility : Not available.
Other adverse effects : No known significant effects or critical hazards.
13. Disposal considerations
Disposal methods : The generation of waste should be avoided or minimized wherever possible. Empty
containers or liners may retain some product residues. This material and its
container must be disposed of in a safe way. Dispose of surplus and non-recyclable
products via a licensed waste disposal contractor. Disposal of this product, solutions
and any by-products should at all times comply with the requirements of
environmental protection and waste disposal legislation and any regional local
authority requirements. Avoid dispersal of spilled material and runoff and contact
with soil, waterways, drains and sewers.
14. Transport information
International transport regulations
IMDG / IATA : Not regulated by any transport mode.
15. Regulatory information
Japan Control Law : Not regulated.
Chemical Substances Control Law (CSCL)
Ingredient name Classification
Biodegradability : Not available.
Concentration of : Not available.
chemicals accumulated in
fish
Japan inventory (ENCS) : See Section 3.
Japan inventory (ISHL) : See Section 3.
Other regulations : Not available.
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16. Other information
History
: 01/15/2008
Date of issue
Version :1
0
References : Not available.
Notice to reader
To the best of our knowledge, the information contained herein is accurate. However, neither the above
named supplier nor any of its subsidiaries assumes any liability whatsoever for the accuracy or completeness
of the information contained herein. Final determination of suitability of any material is the sole responsibility
of the user. All materials may present unknown hazards and should be used with caution. Although certain
hazards are described herein, we cannot guarantee that these are the only hazards that exist.
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