Conforms to ANSI Z400.5-2004 Standard (United States, Canada).
Material Safety Data Sheet
Wash Solution
1. Product and company identification
Product name : Wash Solution
Used in : APTIMA HIV-1 RNA Qualitative Assay 302178, APTIMA HCV RNA Qualitative Assay
302179, APTIMA CT Assay 301088, APTIMA GC Assay 301091, APTIMA Combo 2
301032, APTIMA Assay Fluids Kit 302002C, APTIMA Assay Fluids Kit TIGRIS 302382,
PROGENSA PCA3 Assay Kit CE 302355, PCA3/PSA Supplemental Fluids Kit 302030.
Material uses : In vitro diagnostic.
Supplier/Manufacturer : Gen-Probe Incorporated
10210 Genetic Center Drive
San Diego, CA 92121-4362
MSDS # : 0041
In case of emergency : CANUTEC (613) 996-6666
CHEMTREC, U.S. : (800) 424-9300 International: (703) 527-3887
2. Hazards identification
Physical state : Liquid. [Clear.]
OSHA/HCS status : While this material is not considered hazardous by the OSHA Hazard Communication
Standard (29 CFR 1910.1200), this MSDS contains valuable information critical to the
safe handling and proper use of the product. This MSDS should be retained and
available for employees and other users of this product.
Emergency overview : NOT EXPECTED TO PRODUCE SIGNIFICANT ADVERSE HEALTH EFFECTS WHEN
THE RECOMMENDED INSTRUCTIONS FOR USE ARE FOLLOWED.
No known significant effects or critical hazards. Avoid prolonged contact with eyes, skin
and clothing.
Potential acute health effects
Inhalation : No known significant effects or critical hazards.
Ingestion : No known significant effects or critical hazards.
Skin : No known significant effects or critical hazards.
Eyes : No known significant effects or critical hazards.
Potential chronic health effects
Chronic effects : No known significant effects or critical hazards.
Carcinogenicity : No known significant effects or critical hazards.
Mutagenicity : No known significant effects or critical hazards.
Teratogenicity : No known significant effects or critical hazards.
Developmental effects : No known significant effects or critical hazards.
Fertility effects : No known significant effects or critical hazards.
Over-exposure signs/symptoms
Inhalation : No specific data.
Ingestion : No specific data.
Skin : No specific data.
Eyes : No specific data.
Medical conditions : None known.
aggravated by over-
exposure
See toxicological information (section 11)
: 01/15/2008 Page: 1/6
Date of issue
Wash Solution
3. Composition/information on ingredients
Name CAS number %
No hazardous ingredient
Due to differing non-hazardous components, the products listed in each part number in 鈥淯sed In鈥? section are not
interchangeable. See package insert for product use.
There are no ingredients present which, within the current knowledge of the supplier and in the concentrations
applicable, are classified as hazardous to health or the environment and hence require reporting in this section.
4. First aid measures
Eye contact : Check for and remove any contact lenses. In case of contact with eyes, rinse
immediately with plenty of water. Get medical attention if symptoms occur.
Skin contact : Wash with soap and water. Get medical attention if symptoms occur.
Inhalation : If inhaled, remove to fresh air. If not breathing, give artificial respiration. Get medical
attention if symptoms appear.
Ingestion : Do not induce vomiting. Never give anything by mouth to an unconscious person. Get
medical attention if symptoms appear.
Protection of first-aiders : No action shall be taken involving any personal risk or without suitable training.
Notes to physician : No specific treatment. Treat symptomatically. Contact poison treatment specialist
immediately if large quantities have been ingested or inhaled.
5. Fire-fighting measures
Flammability of the product : Non-flammable.
Extinguishing media
Suitable : Use an extinguishing agent suitable for the surrounding fire.
Not suitable : None known.
Hazardous thermal : No specific data.
decomposition products
Special protective : Fire-fighters should wear appropriate protective equipment and self-contained breathing
apparatus (SCBA) with a full face-piece operated in positive pressure mode.
equipment for fire-fighters
6. Accidental release measures
Personal precautions : No action shall be taken involving any personal risk or without suitable training.
Evacuate surrounding areas. Keep unnecessary and unprotected personnel from
entering. Do not touch or walk through spilled material. Avoid breathing vapor or mist.
Provide adequate ventilation. Wear appropriate respirator when ventilation is
inadequate. Put on appropriate personal protective equipment (see section 8).
Environmental precautions : Avoid dispersal of spilled material and runoff and contact with soil, waterways, drains
and sewers. Inform the relevant authorities if the product has caused environmental
pollution (sewers, waterways, soil or air).
Methods for cleaning up
Small spill : Stop leak if without risk. Move containers from spill area. Dilute with water and mop up
if water-soluble or absorb with an inert dry material and place in an appropriate waste
disposal container. Dispose of via a licensed waste disposal contractor.
: 01/15/2008 Page: 2/6
Date of issue
Wash Solution
6. Accidental release measures
Large spill : Stop leak if without risk. Move containers from spill area. Approach release from
upwind. Prevent entry into sewers, water courses, basements or confined areas. Wash
spillages into an effluent treatment plant or proceed as follows. Contain and collect
spillage with non-combustible, absorbent material e.g. sand, earth, vermiculite or
diatomaceous earth and place in container for disposal according to local regulations
(see section 13). Dispose of via a licensed waste disposal contractor. Contaminated
absorbent material may pose the same hazard as the spilled product. Note: see section
1 for emergency contact information and section 13 for waste disposal.
7. Handling and storage
Handling : Put on appropriate personal protective equipment (see section 8). Eating, drinking and
smoking should be prohibited in areas where this material is handled, stored and
processed. Workers should wash hands and face before eating, drinking and smoking.
Do not ingest. Avoid contact with eyes, skin and clothing. Avoid breathing vapor or mist.
Keep in the original container or an approved alternative made from a compatible
material, kept tightly closed when not in use. Empty containers retain product residue
and can be hazardous. Do not reuse container.
Storage : Store in accordance with local regulations. Store in original container protected from
direct sunlight in a dry, cool and well-ventilated area, away from incompatible materials
(see section 10) and food and drink. Keep container tightly closed and sealed until ready
for use. Containers that have been opened must be carefully resealed and kept upright
to prevent leakage. Do not store in unlabeled containers. Use appropriate containment
to avoid environmental contamination.
8. Exposure controls/personal protection
Consult local authorities for acceptable exposure limits.
Recommended monitoring : If this product contains ingredients with exposure limits, personal, workplace atmosphere
or biological monitoring may be required to determine the effectiveness of the ventilation
procedures
or other control measures and/or the necessity to use respiratory protective equipment.
Engineering measures : No special ventilation requirements. Good general ventilation should be sufficient to
control worker exposure to airborne contaminants. If this product contains ingredients
with exposure limits, use process enclosures, local exhaust ventilation or other
engineering controls to keep worker exposure below any recommended or statutory
limits.
Hygiene measures : Wash hands, forearms and face thoroughly after handling chemical products, before
eating, smoking and using the lavatory and at the end of the working period. Appropriate
techniques should be used to remove potentially contaminated clothing. Wash
contaminated clothing before reusing. Ensure that eyewash stations and safety showers
are close to the workstation location.
Personal protection
Eyes : Safety glasses.
Skin : Lab coat.
Respiratory : A respirator is not needed under normal and intended conditions of product use.
Hands : Disposable vinyl gloves.
Personal protective :
equipment (Pictograms)
HMIS Code/Personal :A
protective equipment
: 01/15/2008 Page: 3/6
Date of issue
Wash Solution
8. Exposure controls/personal protection
Environmental exposure : Emissions from ventilation or work process equipment should be checked to ensure they
comply with the requirements of environmental protection legislation. In some cases,
controls
fume scrubbers, filters or engineering modifications to the process equipment will be
necessary to reduce emissions to acceptable levels.
9. Physical and chemical properties
Physical state : Liquid. [Clear.]
Color : Colorless.
pH : ~ 7.5.
Relative density : ~ 1.
Solubility : Miscible in water.
10 . Stability and reactivity
Stability : The product is stable.
Hazardous polymerization : Under normal conditions of storage and use, hazardous polymerization will not occur.
Conditions to avoid : No specific data.
Materials to avoid : No specific data.
Hazardous decomposition : Under normal conditions of storage and use, hazardous decomposition products should
not be produced.
products
11 . Toxicological information
Acute toxicity
Inhalation No known significant effects or critical hazards.
:
Ingestion : No known significant effects or critical hazards.
Skin : No known significant effects or critical hazards.
Eyes : No known significant effects or critical hazards.
12 . Ecological information
Environmental effects : No known significant effects or critical hazards.
Other adverse effects : No known significant effects or critical hazards.
13 . Disposal considerations
Waste disposal : The generation of waste should be avoided or minimized wherever possible. Empty
containers or liners may retain some product residues. This material and its container
must be disposed of in a safe way. Dispose of surplus and non-recyclable products via
a licensed waste disposal contractor. Disposal of this product, solutions and any by-
products should at all times comply with the requirements of environmental protection
and waste disposal legislation and any regional local authority requirements. Avoid
dispersal of spilled material and runoff and contact with soil, waterways, drains and
sewers.
Disposal should be in accordance with applicable regional, national and local laws and regulations.
Refer to Section 7: HANDLING AND STORAGE and Section 8: EXPOSURE CONTROLS/PERSONAL PROTECTION
for additional handling information and protection of employees.
: 01/15/2008 Page: 4/6
Date of issue
Wash Solution
14 . Transport information
AERG : Not applicable.
Regulatory information
DOT/ TDG / IMDG/ IATA : Not regulated.
15 . Regulatory information
United States
HCS Classification : Not regulated.
U.S. Federal regulations : United States inventory (TSCA 8b): All components are listed or exempted.
SARA 302/304/311/312 extremely hazardous substances: No products were found.
SARA 302/304 emergency planning and notification: No products were found.
SARA 302/304/311/312 hazardous chemicals: No products were found.
SARA 311/312 MSDS distribution - chemical inventory - hazard identification: No
products were found.
Clean Water Act (CWA) 307: No products were found.
Clean Water Act (CWA) 311: Sodium hydroxide; Ethylenediamine tetraacetic acid
Clean Air Act (CAA) 112 accidental release prevention: No products were found.
Clean Air Act (CAA) 112 regulated flammable substances: No products were found.
Clean Air Act (CAA) 112 regulated toxic substances: No products were found.
State regulations : Connecticut Carcinogen Reporting: None of the components are listed.
Connecticut Hazardous Material Survey: None of the components are listed.
Florida substances: None of the components are listed.
Illinois Chemical Safety Act: None of the components are listed.
Illinois Toxic Substances Disclosure to Employee Act: None of the components are
listed.
Louisiana Reporting: None of the components are listed.
Louisiana Spill: None of the components are listed.
Massachusetts Spill: None of the components are listed.
Massachusetts Substances: None of the components are listed.
Michigan Critical Material: None of the components are listed.
Minnesota Hazardous Substances: None of the components are listed.
New Jersey Hazardous Substances: None of the components are listed.
New Jersey Spill: None of the components are listed.
New Jersey Toxic Catastrophe Prevention Act: None of the components are listed.
New York Acutely Hazardous Substances: None of the components are listed.
New York Toxic Chemical Release Reporting: None of the components are listed.
Pennsylvania RTK Hazardous Substances: None of the components are listed.
Rhode Island Hazardous Substances: None of the components are listed.
California Prop. 65
California prop. 65: No products were found.
Canada
WHMIS (Canada) : Not controlled under WHMIS (Canada).
Canadian lists : CEPA Toxic substances: None of the components are listed.
Canadian ARET: None of the components are listed.
Canadian NPRI: None of the components are listed.
Alberta Designated Substances: None of the components are listed.
Ontario Designated Substances: None of the components are listed.
Quebec Designated Substances: None of the components are listed.
Canada inventory : Canada inventory: All components listed.
This product has been classified in accordance with the hazard criteria of the Controlled Products Regulations
and the MSDS contains all the information required by the Controlled Products Regulations.
International regulations
: 01/15/2008 Page: 5/6
Date of issue
Wash Solution
15 . Regulatory information
International lists : This product, (and its ingredients) is (are) listed on national inventories, or is (are)
exempted from being listed, in Australia (AICS), in Europe (EINECS/ELINCS), in Korea
(TCCL), in Japan (METI), in the Philippines (RA6969).
16 . Other information
Label requirements : NOT EXPECTED TO PRODUCE SIGNIFICANT ADVERSE HEALTH EFFECTS WHEN
THE RECOMMENDED INSTRUCTIONS FOR USE ARE FOLLOWED.
Hazardous Material : HAZARD RATINGS
Information System (U.S.A.)
0
Health 4- Extreme
3- Serious
0
Fire hazard 2- Moderate
1- Slight
0
Physical Hazard 0- Minimal
See section 8 for more detailed
A
Personal protection information on personal protection.
The customer is responsible for determining the PPE code for this material.
National Fire Protection :
Association (U.S.A.)
Flammability
0
0 0
Health Instability
Special
References : ANSI Z400.5, MSDS Standard, 2004. - Manufacturer's Material Safety Data Sheet. -
29CFR Part1910.1200 OSHA MSDS Requirements. - 49CFR Table List of Hazardous
Materials, UN#, Proper Shipping Names, PG. - Canada Gazette Part II, Vol. 122, No. 2.
Registration SOR/88-64, 31 December 1987. Hazardous Products Act "Ingredient
Disclosure List" - Canadian Transport of Dangerous Goods, Regulations and Schedules,
Clear Language version 2005.
: 01/15/2008
Date of issue
Date of previous issue : 08/15/2007
Version : 1.1
Notice to reader
To the best of our knowledge, the information contained herein is accurate. However, neither the above named
supplier nor any of its subsidiaries assumes any liability whatsoever for the accuracy or completeness of the
information contained herein. Final determination of suitability of any material is the sole responsibility of the
user. All materials may present unknown hazards and should be used with caution. Although certain hazards are
described herein, we cannot guarantee that these are the only hazards that exist.
: 01/15/2008 Page: 6/6
Date of issue
Conforms to ANSI Z400.5-2004 Standard (United States, Canada).
Material Safety Data Sheet
Oil Reagent
1. Product and company identification
Product name : Oil Reagent
Used in : APTIMA HIV-1 RNA Qualitative Assay 302178, APTIMA HCV RNA Qualitative Assay
302179, APTIMA CT Assay 301088, APTIMA GC Assay 301091, APTIMA Combo 2
301032, APTIMA Assay Fluids Kit 302002C, APTIMA Assay Fluids Kit TIGRIS 302382,
PROGENSA PCA3 Assay Kit CE 302355, PCA3/PSA Supplemental Fluids Kit 302030.
Material uses : In vitro diagnostic.
Supplier/Manufacturer : Gen-Probe Incorporated
10210 Genetic Center Drive
San Diego, CA 92121-4362
MSDS # : 0042
In case of emergency : CANUTEC (613) 996-6666
CHEMTREC, U.S. : (800) 424-9300 International: (703) 527-3887
2. Hazards identification
Physical state : Liquid. [Clear.]
Odor : Odorless.
OSHA/HCS status : While this material is not considered hazardous by the OSHA Hazard Communication
Standard (29 CFR 1910.1200), this MSDS contains valuable information critical to the
safe handling and proper use of the product. This MSDS should be retained and
available for employees and other users of this product.
Emergency overview : NOT EXPECTED TO PRODUCE SIGNIFICANT ADVERSE HEALTH EFFECTS WHEN
THE RECOMMENDED INSTRUCTIONS FOR USE ARE FOLLOWED.
No known significant effects or critical hazards. Avoid prolonged contact with eyes, skin
and clothing.
Potential acute health effects
Inhalation : No known significant effects or critical hazards.
Ingestion : No known significant effects or critical hazards.
Skin : No known significant effects or critical hazards.
Eyes : No known significant effects or critical hazards.
Potential chronic health effects
Chronic effects : No known significant effects or critical hazards.
Carcinogenicity : No known significant effects or critical hazards.
Mutagenicity : No known significant effects or critical hazards.
Teratogenicity : No known significant effects or critical hazards.
Developmental effects : No known significant effects or critical hazards.
Fertility effects : No known significant effects or critical hazards.
Over-exposure signs/symptoms
Inhalation : No specific data.
Ingestion : No specific data.
Skin : No specific data.
Eyes : No specific data.
Medical conditions : None known.
aggravated by over-
exposure
See toxicological information (section 11)
: 01/15/2008 Page: 1/6
Date of issue
Oil Reagent
3. Composition/information on ingredients
Name CAS number %
No hazardous ingredient
Due to differing non-hazardous components, the products listed in each part number in 鈥淯sed In鈥? section are not
interchangeable. See package insert for product use.
There are no ingredients present which, within the current knowledge of the supplier and in the concentrations
applicable, are classified as hazardous to health or the environment and hence require reporting in this section.
4. First aid measures
Eye contact : Check for and remove any contact lenses. In case of contact with eyes, rinse
immediately with plenty of water. Get medical attention if symptoms occur.
Skin contact : Wash with soap and water. Get medical attention if symptoms occur.
Inhalation : If inhaled, remove to fresh air. If not breathing, give artificial respiration. Get medical
attention if symptoms appear.
Ingestion : Do not induce vomiting. Never give anything by mouth to an unconscious person. Get
medical attention if symptoms appear.
Protection of first-aiders : No action shall be taken involving any personal risk or without suitable training.
Notes to physician : No specific treatment. Treat symptomatically. Contact poison treatment specialist
immediately if large quantities have been ingested or inhaled.
5. Fire-fighting measures
Flammability of the product : Non-flammable.
Extinguishing media
Suitable : Use an extinguishing agent suitable for the surrounding fire.
Not suitable : None known.
Hazardous thermal : No specific data.
decomposition products
Special protective : Fire-fighters should wear appropriate protective equipment and self-contained breathing
apparatus (SCBA) with a full face-piece operated in positive pressure mode.
equipment for fire-fighters
6. Accidental release measures
Personal precautions : No action shall be taken involving any personal risk or without suitable training.
Evacuate surrounding areas. Keep unnecessary and unprotected personnel from
entering. Do not touch or walk through spilled material. Avoid breathing vapor or mist.
Provide adequate ventilation. Wear appropriate respirator when ventilation is
inadequate. Put on appropriate personal protective equipment (see section 8).
Environmental precautions : Avoid dispersal of spilled material and runoff and contact with soil, waterways, drains
and sewers. Inform the relevant authorities if the product has caused environmental
pollution (sewers, waterways, soil or air).
Methods for cleaning up
Small spill : Stop leak if without risk. Move containers from spill area. Dilute with water and mop up
if water-soluble or absorb with an inert dry material and place in an appropriate waste
disposal container. Dispose of via a licensed waste disposal contractor.
: 01/15/2008 Page: 2/6
Date of issue
Oil Reagent
6. Accidental release measures
Large spill : Stop leak if without risk. Move containers from spill area. Approach release from
upwind. Prevent entry into sewers, water courses, basements or confined areas. Wash
spillages into an effluent treatment plant or proceed as follows. Contain and collect
spillage with non-combustible, absorbent material e.g. sand, earth, vermiculite or
diatomaceous earth and place in container for disposal according to local regulations
(see section 13). Dispose of via a licensed waste disposal contractor. Contaminated
absorbent material may pose the same hazard as the spilled product. Note: see section
1 for emergency contact information and section 13 for waste disposal.
7. Handling and storage
Handling : Put on appropriate personal protective equipment (see section 8). Eating, drinking and
smoking should be prohibited in areas where this material is handled, stored and
processed. Workers should wash hands and face before eating, drinking and smoking.
Do not ingest. Avoid contact with eyes, skin and clothing. Avoid breathing vapor or mist.
Keep in the original container or an approved alternative made from a compatible
material, kept tightly closed when not in use. Empty containers retain product residue
and can be hazardous. Do not reuse container.
Storage : Store in accordance with local regulations. Store in original container protected from
direct sunlight in a dry, cool and well-ventilated area, away from incompatible materials
(see section 10) and food and drink. Keep container tightly closed and sealed until ready
for use. Containers that have been opened must be carefully resealed and kept upright
to prevent leakage. Do not store in unlabeled containers. Use appropriate containment
to avoid environmental contamination.
8. Exposure controls/personal protection
Consult local authorities for acceptable exposure limits.
Recommended monitoring : If this product contains ingredients with exposure limits, personal, workplace atmosphere
or biological monitoring may be required to determine the effectiveness of the ventilation
procedures
or other control measures and/or the necessity to use respiratory protective equipment.
Engineering measures : No special ventilation requirements. Good general ventilation should be sufficient to
control worker exposure to airborne contaminants. If this product contains ingredients
with exposure limits, use process enclosures, local exhaust ventilation or other
engineering controls to keep worker exposure below any recommended or statutory
limits.
Hygiene measures : Wash hands, forearms and face thoroughly after handling chemical products, before
eating, smoking and using the lavatory and at the end of the working period. Appropriate
techniques should be used to remove potentially contaminated clothing. Wash
contaminated clothing before reusing. Ensure that eyewash stations and safety showers
are close to the workstation location.
Personal protection
Eyes : Safety glasses.
Skin : Lab coat.
Respiratory : A respirator is not needed under normal and intended conditions of product use.
Hands : Disposable vinyl gloves.
Personal protective :
equipment (Pictograms)
HMIS Code/Personal :A
protective equipment
: 01/15/2008 Page: 3/6
Date of issue
Oil Reagent
8. Exposure controls/personal protection
Environmental exposure : Emissions from ventilation or work process equipment should be checked to ensure they
comply with the requirements of environmental protection legislation. In some cases,
controls
fume scrubbers, filters or engineering modifications to the process equipment will be
necessary to reduce emissions to acceptable levels.
9. Physical and chemical properties
Physical state : Liquid. [Clear.]
Color : Colorless.
Odor : Odorless.
Solubility : Insoluble in the following materials: cold water and hot water.
10 . Stability and reactivity
Stability : The product is stable.
Hazardous polymerization : Under normal conditions of storage and use, hazardous polymerization will not occur.
Conditions to avoid : No specific data.
Materials to avoid : No specific data.
Hazardous decomposition : Under normal conditions of storage and use, hazardous decomposition products should
not be produced.
products
11 . Toxicological information
Acute toxicity
Inhalation No known significant effects or critical hazards.
:
Ingestion : No known significant effects or critical hazards.
Skin : No known significant effects or critical hazards.
Eyes : No known significant effects or critical hazards.
12 . Ecological information
Environmental effects : No known significant effects or critical hazards.
Other adverse effects : No known significant effects or critical hazards.
13 . Disposal considerations
Waste disposal : The generation of waste should be avoided or minimized wherever possible. Empty
containers or liners may retain some product residues. This material and its container
must be disposed of in a safe way. Dispose of surplus and non-recyclable products via
a licensed waste disposal contractor. Disposal of this product, solutions and any by-
products should at all times comply with the requirements of environmental protection
and waste disposal legislation and any regional local authority requirements. Avoid
dispersal of spilled material and runoff and contact with soil, waterways, drains and
sewers.
Disposal should be in accordance with applicable regional, national and local laws and regulations.
Refer to Section 7: HANDLING AND STORAGE and Section 8: EXPOSURE CONTROLS/PERSONAL PROTECTION
for additional handling information and protection of employees.
: 01/15/2008 Page: 4/6
Date of issue
Oil Reagent
14 . Transport information
AERG : Not applicable.
Regulatory information
DOT/ TDG / IMDG/ IATA : Not regulated.
15 . Regulatory information
United States
HCS Classification : Not regulated.
U.S. Federal regulations : TSCA 8(a) PAIR: Dimethyl silicone and siloxanes
United States inventory (TSCA 8b): All components listed.
SARA 302/304/311/312 extremely hazardous substances: No products were found.
SARA 302/304 emergency planning and notification: No products were found.
SARA 302/304/311/312 hazardous chemicals: No products were found.
SARA 311/312 MSDS distribution - chemical inventory - hazard identification: No
products were found.
Clean Water Act (CWA) 307: No products were found.
Clean Water Act (CWA) 311: No products were found.
Clean Air Act (CAA) 112 accidental release prevention: No products were found.
Clean Air Act (CAA) 112 regulated flammable substances: No products were found.
Clean Air Act (CAA) 112 regulated toxic substances: No products were found.
State regulations : Connecticut Carcinogen Reporting: None of the components are listed.
Connecticut Hazardous Material Survey: None of the components are listed.
Florida substances: None of the components are listed.
Illinois Chemical Safety Act: None of the components are listed.
Illinois Toxic Substances Disclosure to Employee Act: None of the components are
listed.
Louisiana Reporting: None of the components are listed.
Louisiana Spill: None of the components are listed.
Massachusetts Spill: None of the components are listed.
Massachusetts Substances: None of the components are listed.
Michigan Critical Material: None of the components are listed.
Minnesota Hazardous Substances: None of the components are listed.
New Jersey Hazardous Substances: None of the components are listed.
New Jersey Spill: None of the components are listed.
New Jersey Toxic Catastrophe Prevention Act: None of the components are listed.
New York Acutely Hazardous Substances: None of the components are listed.
New York Toxic Chemical Release Reporting: None of the components are listed.
Pennsylvania RTK Hazardous Substances: None of the components are listed.
Rhode Island Hazardous Substances: None of the components are listed.
California Prop. 65
California prop. 65: No products were found.
Canada
WHMIS (Canada) : Not controlled under WHMIS (Canada).
Canadian lists : CEPA Toxic substances: None of the components are listed.
Canadian ARET: None of the components are listed.
Canadian NPRI: None of the components are listed.
Alberta Designated Substances: None of the components are listed.
Ontario Designated Substances: None of the components are listed.
Quebec Designated Substances: None of the components are listed.
Canada inventory : Canada inventory: All components listed.
This product has been classified in accordance with the hazard criteria of the Controlled Products Regulations
and the MSDS contains all the information required by the Controlled Products Regulations.
: 01/15/2008 Page: 5/6
Date of issue
Oil Reagent
15 . Regulatory information
International regulations
International lists : This product, (and its ingredients) is (are) listed on national inventories, or is (are)
exempted from being listed, in Australia (AICS), in Europe (EINECS/ELINCS), in Korea
(TCCL), in Japan (METI), in the Philippines (RA6969).
16 . Other information
Label requirements : NOT EXPECTED TO PRODUCE SIGNIFICANT ADVERSE HEALTH EFFECTS WHEN
THE RECOMMENDED INSTRUCTIONS FOR USE ARE FOLLOWED.
Hazardous Material : HAZARD RATINGS
Information System (U.S.A.)
0
Health 4- Extreme
3- Serious
0
Fire hazard 2- Moderate
1- Slight
0
Physical Hazard 0- Minimal
See section 8 for more detailed
A
Personal protection information on personal protection.
The customer is responsible for determining the PPE code for this material.
National Fire Protection :
Association (U.S.A.)
Flammability
0
0 0
Health Instability
Special
References : ANSI Z400.5, MSDS Standard, 2004. - Manufacturer's Material Safety Data Sheet. -
29CFR Part1910.1200 OSHA MSDS Requirements. - 49CFR Table List of Hazardous
Materials, UN#, Proper Shipping Names, PG. - Canada Gazette Part II, Vol. 122, No. 2.
Registration SOR/88-64, 31 December 1987. Hazardous Products Act "Ingredient
Disclosure List" - Canadian Transport of Dangerous Goods, Regulations and Schedules,
Clear Language version 2005.
: 01/15/2008
Date of issue
Date of previous issue : 08/15/2007
Version : 1.1
Notice to reader
To the best of our knowledge, the information contained herein is accurate. However, neither the above named
supplier nor any of its subsidiaries assumes any liability whatsoever for the accuracy or completeness of the
information contained herein. Final determination of suitability of any material is the sole responsibility of the
user. All materials may present unknown hazards and should be used with caution. Although certain hazards are
described herein, we cannot guarantee that these are the only hazards that exist.
: 01/15/2008 Page: 6/6
Date of issue
Conforms to ANSI Z400.5-2004 Standard (United States, Canada).
Material Safety Data Sheet
Buffer for Deactivation Fluid
1. Product and company identification
Product name : Buffer for Deactivation Fluid
Used in : APTIMA HIV-1 RNA Qualitative Assay 302178, APTIMA HCV RNA Qualitative Assay
302179, APTIMA CT Assay 301088, APTIMA GC Assay 301091, APTIMA Combo 2
301032, APTIMA Assay Fluids Kit 302002C, APTIMA Assay Fluids Kit TIGRIS 302382,
PROGENSA PCA3 Assay Kit CE 302355, PCA3/PSA Supplemental Fluids Kit 302030.
Material uses : In vitro diagnostic.
Supplier/Manufacturer : Gen-Probe Incorporated
10210 Genetic Center Drive
San Diego, CA 92121-4362
MSDS # : 0043
In case of emergency : CANUTEC (613) 996-6666
CHEMTREC, U.S. : (800) 424-9300 International: (703) 527-3887
2. Hazards identification
Physical state : Liquid. [Clear.]
OSHA/HCS status : While this material is not considered hazardous by the OSHA Hazard Communication
Standard (29 CFR 1910.1200), this MSDS contains valuable information critical to the
safe handling and proper use of the product. This MSDS should be retained and
available for employees and other users of this product.
Emergency overview : NOT EXPECTED TO PRODUCE SIGNIFICANT ADVERSE HEALTH EFFECTS WHEN
THE RECOMMENDED INSTRUCTIONS FOR USE ARE FOLLOWED.
No known significant effects or critical hazards. Avoid prolonged contact with eyes, skin
and clothing.
Routes of entry : Dermal contact. Eye contact. Inhalation. Ingestion.
Potential acute health effects
Inhalation : No known significant effects or critical hazards.
Ingestion : No known significant effects or critical hazards.
Skin : No known significant effects or critical hazards.
Eyes : No known significant effects or critical hazards.
Potential chronic health effects
Chronic effects : No known significant effects or critical hazards.
Carcinogenicity : No known significant effects or critical hazards.
Mutagenicity : No known significant effects or critical hazards.
Teratogenicity : No known significant effects or critical hazards.
Developmental effects : No known significant effects or critical hazards.
Fertility effects : No known significant effects or critical hazards.
Over-exposure signs/symptoms
Inhalation : No specific data.
Ingestion : No specific data.
Skin : No specific data.
Eyes : No specific data.
Medical conditions : None known.
aggravated by over-
exposure
See toxicological information (section 11)
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3. Composition/information on ingredients
Name CAS number %
No hazardous ingredient
Due to differing non-hazardous components, the products listed in each part number in 鈥淯sed In鈥? section are not
interchangeable. See package insert for product use.
There are no ingredients present which, within the current knowledge of the supplier and in the concentrations
applicable, are classified as hazardous to health or the environment and hence require reporting in this section.
4. First aid measures
Eye contact : Check for and remove any contact lenses. In case of contact with eyes, rinse
immediately with plenty of water. Get medical attention if symptoms occur.
Skin contact : Wash with soap and water. Get medical attention if symptoms occur.
Inhalation : If inhaled, remove to fresh air. If not breathing, give artificial respiration. Get medical
attention if symptoms appear.
Ingestion : Do not induce vomiting. Never give anything by mouth to an unconscious person. Get
medical attention if symptoms appear.
Protection of first-aiders : No action shall be taken involving any personal risk or without suitable training.
Notes to physician : No specific treatment. Treat symptomatically. Contact poison treatment specialist
immediately if large quantities have been ingested or inhaled.
5. Fire-fighting measures
Flammability of the product : Non-flammable.
Extinguishing media
Suitable : Use an extinguishing agent suitable for the surrounding fire.
Not suitable : None known.
Hazardous thermal : Decomposition products may include the following materials:
carbon dioxide
decomposition products
carbon monoxide
metal oxide/oxides
Special protective : Fire-fighters should wear appropriate protective equipment and self-contained breathing
apparatus (SCBA) with a full face-piece operated in positive pressure mode.
equipment for fire-fighters
6. Accidental release measures
Personal precautions : No action shall be taken involving any personal risk or without suitable training.
Evacuate surrounding areas. Keep unnecessary and unprotected personnel from
entering. Do not touch or walk through spilled material. Avoid breathing vapor or mist.
Provide adequate ventilation. Wear appropriate respirator when ventilation is
inadequate. Put on appropriate personal protective equipment (see section 8).
Environmental precautions : Avoid dispersal of spilled material and runoff and contact with soil, waterways, drains
and sewers. Inform the relevant authorities if the product has caused environmental
pollution (sewers, waterways, soil or air).
Methods for cleaning up
Small spill : Stop leak if without risk. Move containers from spill area. Dilute with water and mop up
if water-soluble or absorb with an inert dry material and place in an appropriate waste
disposal container. Dispose of via a licensed waste disposal contractor.
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6. Accidental release measures
Large spill : Stop leak if without risk. Move containers from spill area. Approach release from
upwind. Prevent entry into sewers, water courses, basements or confined areas. Wash
spillages into an effluent treatment plant or proceed as follows. Contain and collect
spillage with non-combustible, absorbent material e.g. sand, earth, vermiculite or
diatomaceous earth and place in container for disposal according to local regulations
(see section 13). Dispose of via a licensed waste disposal contractor. Contaminated
absorbent material may pose the same hazard as the spilled product. Note: see section
1 for emergency contact information and section 13 for waste disposal.
7. Handling and storage
Handling : Put on appropriate personal protective equipment (see section 8). Eating, drinking and
smoking should be prohibited in areas where this material is handled, stored and
processed. Workers should wash hands and face before eating, drinking and smoking.
Do not ingest. Avoid contact with eyes, skin and clothing. Avoid breathing vapor or mist.
Keep in the original container or an approved alternative made from a compatible
material, kept tightly closed when not in use. Empty containers retain product residue
and can be hazardous. Do not reuse container.
Storage : Store in accordance with local regulations. Store in original container protected from
direct sunlight in a dry, cool and well-ventilated area, away from incompatible materials
(see section 10) and food and drink. Keep container tightly closed and sealed until ready
for use. Containers that have been opened must be carefully resealed and kept upright
to prevent leakage. Do not store in unlabeled containers. Use appropriate containment
to avoid environmental contamination.
8. Exposure controls/personal protection
Consult local authorities for acceptable exposure limits.
Recommended monitoring : If this product contains ingredients with exposure limits, personal, workplace atmosphere
or biological monitoring may be required to determine the effectiveness of the ventilation
procedures
or other control measures and/or the necessity to use respiratory protective equipment.
Engineering measures : No special ventilation requirements. Good general ventilation should be sufficient to
control worker exposure to airborne contaminants. If this product contains ingredients
with exposure limits, use process enclosures, local exhaust ventilation or other
engineering controls to keep worker exposure below any recommended or statutory
limits.
Hygiene measures : Wash hands, forearms and face thoroughly after handling chemical products, before
eating, smoking and using the lavatory and at the end of the working period. Appropriate
techniques should be used to remove potentially contaminated clothing. Wash
contaminated clothing before reusing. Ensure that eyewash stations and safety showers
are close to the workstation location.
Personal protection
Eyes : Safety glasses.
Skin : Lab coat.
Respiratory : A respirator is not needed under normal and intended conditions of product use.
Hands : Disposable vinyl gloves.
Personal protective :
equipment (Pictograms)
HMIS Code/Personal :A
protective equipment
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8. Exposure controls/personal protection
Environmental exposure : Emissions from ventilation or work process equipment should be checked to ensure they
comply with the requirements of environmental protection legislation. In some cases,
controls
fume scrubbers, filters or engineering modifications to the process equipment will be
necessary to reduce emissions to acceptable levels.
9. Physical and chemical properties
Physical state : Liquid. [Clear.]
Color : Colorless.
pH : ~ 9.3.
Relative density : ~ 1.
10 . Stability and reactivity
Stability : The product is stable.
Hazardous polymerization : Under normal conditions of storage and use, hazardous polymerization will not occur.
Conditions to avoid : No specific data.
Materials to avoid : No specific data.
Hazardous decomposition : Under normal conditions of storage and use, hazardous decomposition products should
not be produced.
products
11 . Toxicological information
Acute toxicity
Inhalation No known significant effects or critical hazards.
:
Ingestion : No known significant effects or critical hazards.
Skin : No known significant effects or critical hazards.
Eyes : No known significant effects or critical hazards.
12 . Ecological information
Environmental effects : No known significant effects or critical hazards.
Other adverse effects : No known significant effects or critical hazards.
13 . Disposal considerations
Waste disposal : The generation of waste should be avoided or minimized wherever possible. Empty
containers or liners may retain some product residues. This material and its container
must be disposed of in a safe way. Dispose of surplus and non-recyclable products via
a licensed waste disposal contractor. Disposal of this product, solutions and any by-
products should at all times comply with the requirements of environmental protection
and waste disposal legislation and any regional local authority requirements. Avoid
dispersal of spilled material and runoff and contact with soil, waterways, drains and
sewers.
Disposal should be in accordance with applicable regional, national and local laws and regulations.
Refer to Section 7: HANDLING AND STORAGE and Section 8: EXPOSURE CONTROLS/PERSONAL PROTECTION
for additional handling information and protection of employees.
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14 . Transport information
AERG : Not applicable.
Regulatory information
DOT/ TDG / IMDG/ IATA : Not regulated.
15 . Regulatory information
United States
HCS Classification : Not regulated.
U.S. Federal regulations : United States inventory (TSCA 8b): All components listed.
SARA 302/304/311/312 extremely hazardous substances: No products were found.
SARA 302/304 emergency planning and notification: No products were found.
SARA 302/304/311/312 hazardous chemicals: No products were found.
SARA 311/312 MSDS distribution - chemical inventory - hazard identification: No
products were found.
Clean Water Act (CWA) 307: No products were found.
Clean Water Act (CWA) 311: Sodium hydroxide; Sodium Hypochlorite
Clean Air Act (CAA) 112 accidental release prevention: No products were found.
Clean Air Act (CAA) 112 regulated flammable substances: No products were found.
Clean Air Act (CAA) 112 regulated toxic substances: No products were found.
State regulations : Connecticut Carcinogen Reporting: None of the components are listed.
Connecticut Hazardous Material Survey: None of the components are listed.
Florida substances: None of the components are listed.
Illinois Chemical Safety Act: None of the components are listed.
Illinois Toxic Substances Disclosure to Employee Act: None of the components are
listed.
Louisiana Reporting: None of the components are listed.
Louisiana Spill: None of the components are listed.
Massachusetts Spill: None of the components are listed.
Massachusetts Substances: None of the components are listed.
Michigan Critical Material: None of the components are listed.
Minnesota Hazardous Substances: None of the components are listed.
New Jersey Hazardous Substances: None of the components are listed.
New Jersey Spill: None of the components are listed.
New Jersey Toxic Catastrophe Prevention Act: None of the components are listed.
New York Acutely Hazardous Substances: None of the components are listed.
New York Toxic Chemical Release Reporting: None of the components are listed.
Pennsylvania RTK Hazardous Substances: None of the components are listed.
Rhode Island Hazardous Substances: None of the components are listed.
Canada
WHMIS (Canada) : Not controlled under WHMIS (Canada).
Canadian lists : CEPA Toxic substances: None of the components are listed.
Canadian ARET: None of the components are listed.
Canadian NPRI: None of the components are listed.
Alberta Designated Substances: None of the components are listed.
Ontario Designated Substances: None of the components are listed.
Quebec Designated Substances: None of the components are listed.
Canada inventory : Canada inventory: All components listed.
This product has been classified in accordance with the hazard criteria of the Controlled Products Regulations
and the MSDS contains all the information required by the Controlled Products Regulations.
International regulations
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15 . Regulatory information
International lists : This product, (and its ingredients) is (are) listed on national inventories, or is (are)
exempted from being listed, in Australia (AICS), in Europe (EINECS/ELINCS), in Korea
(TCCL), in Japan (METI), in the Philippines (RA6969).
16 . Other information
Label requirements : NOT EXPECTED TO PRODUCE SIGNIFICANT ADVERSE HEALTH EFFECTS WHEN
THE RECOMMENDED INSTRUCTIONS FOR USE ARE FOLLOWED.
Hazardous Material : HAZARD RATINGS
Information System (U.S.A.)
0
Health 4- Extreme
3- Serious
0
Fire hazard 2- Moderate
1- Slight
0
Physical Hazard 0- Minimal
See section 8 for more detailed
A
Personal protection information on personal protection.
The customer is responsible for determining the PPE code for this material.
National Fire Protection :
Association (U.S.A.)
Flammability
0
0 0
Health Instability
Special
References : ANSI Z400.5, MSDS Standard, 2004. - Manufacturer's Material Safety Data Sheet. -
29CFR Part1910.1200 OSHA MSDS Requirements. - 49CFR Table List of Hazardous
Materials, UN#, Proper Shipping Names, PG. - Canada Gazette Part II, Vol. 122, No. 2.
Registration SOR/88-64, 31 December 1987. Hazardous Products Act "Ingredient
Disclosure List" - Canadian Transport of Dangerous Goods, Regulations and Schedules,
Clear Language version 2005.
: 01/15/2008
Date of issue
Date of previous issue : 08/15/2007
Version : 1.1
Notice to reader
To the best of our knowledge, the information contained herein is accurate. However, neither the above named
supplier nor any of its subsidiaries assumes any liability whatsoever for the accuracy or completeness of the
information contained herein. Final determination of suitability of any material is the sole responsibility of the
user. All materials may present unknown hazards and should be used with caution. Although certain hazards are
described herein, we cannot guarantee that these are the only hazards that exist.
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