Material Safety Data Sheet
Gen-Probe Incorporated Phone: 858-410-8000
10210 Genetic Center Drive Prepared: 3/10/05
San Diego, CA 92121-4362 Updated:
Page 1 of 7
Product Name: Procleix Ultrio Assay
Product Description: Target Capture Reagent Modifier
MSDS Number: 400174
I. Product and Company Description
Gen-Probe Incorporated.
10210 Genetic Center Drive
San Diego, CA 92121-4362
For Product Information/Emergency Phone Number:
(800) 424-9300 (CHEMTREC US)
(703) 527-3887 (CHEMTREC International)
(858) 410-8000 (Gen-Probe Corporate Office)
Distributed by:
Chiron Corporation
4560 Horton Street
Emeryville, CA 94608
Telephone: 510.655.8729
For product use see insert
Chemical Name or Synonym:
N/A
II. Chemical Composition
Component CAS # %Composition
Water 7732-18-5 92
Lithium Hydroxide Monohydrate 1310-65-2 8
III. Hazards Identification
A. Emergency Overview:
Information Pertaining To Particular Dangers For Man And Environment:
Irritant to eyes, mucous membranes and skin. Not to be inhaled or taken internally.
Physical Appearance:
Clear, colorless liquid with no odor
Material Safety Data Sheet
Gen-Probe Incorporated Phone: 858-410-8000
10210 Genetic Center Drive Prepared: 3/10/05
San Diego, CA 92121-4362 Updated:
Page 2 of 7
B. Potential Health Effects:
Acute Eye:
May cause irritation, redness, damage to the cornea, and blindness with prolonged exposure and
concentration.
Acute Skin:
May cause irritation, redness, burns, ulceration, and scarring. Prolonged exposure may cause
dermatitis.
Acute Inhalation:
Corrosive. Extremely destructive to tissues of the mucous membranes and upper respiratory
tract. Symptoms may include burning sensation, coughing, wheezing, laryngitis, shortness of
breath, headache, nausea and vomiting. Inhalation may be fatal as a result of spasm
inflammation and edema of the larynx and bronchi, chemical pneumonitis and pulmonary edema.
Acute ingestion:
Swallowing can cause severe burns of the mouth, throat, and stomach, leading to death. Can
cause sore throat, vomiting, diarrhea. In severe cases, lithium can cause apathy, sluggishness,
drowsiness, slurred speech, blurred vision, irregular eye movements, weakness, incoordination,
lethargy, heart effects, brain effects, ringing in the ears, tremors and muscle twitching, central
nervous system damage, kidney effects, thyroid changes, coma, pulmonary edema, and renal
failure.
Medical Conditions Generally Aggravated by Exposure:
Pre-existing dermatitis other skin conditions and disorders involving the target organs may be
aggravated by exposure to this product.
IV. First Aid Measures
First Aid Measures for Accidental:
Eye Exposure:
Immediately flush eyes with copious amounts of water for at least 15 minutes. If irritation
develops, SEEK MEDICAL ATTENTION.
Skin Exposure:
Wash affected areas with soap and water. If irritation develops, SEEK MEDICAL ATTENTION.
Inhalation:
Move to fresh air. If not breathing, administer artificial respiration. If breathing is difficult, give
oxygen. SEEK MEDICAL ATTENTION.
Ingestion:
If swallowed, rinse mouth out with water. Never give fluids or induce vomiting if the victim is
unconscious or having convulsions. SEEK MEDICAL ATTENTION.
Material Safety Data Sheet
Gen-Probe Incorporated Phone: 858-410-8000
10210 Genetic Center Drive Prepared: 3/10/05
San Diego, CA 92121-4362 Updated:
Page 3 of 7
V. Fire Fighting Measures
Fire Hazard Data:
Autoignition: NA
Flash Point: NA
Flammability Limits (vol/vol%): Lower: Upper:
NA NA
Extinguishing Media:
Use extinguishing media appropriate for surrounding fire
Special Fire Fighting Procedures:
None
Unusual Fire and Explosion Hazards:
The components of this product may decompose and produce nitrogen oxides and sodium
oxides and other compounds.
VI. Accidental Release Measures
Cleanup and Disposal of Spill:
Wear suitable laboratory protective clothing. Absorb spill with citric acid or other agent suitable for bases.
Discard any product, residue, disposable container or liner in full compliance with national regulations.
VII. Handling and Storage
Handling/Storage:
Observe good laboratory handling practices. Always wash hands thoroughly after removing protective
gloves. Avoid breathing vapors or mists. Ensure containers are labeled and tightly closed. Store product
in a temperature controlled environment (15-30掳C/59-86掳F).
VIII. Exposure Controls / Personal Protection
Exposure Guidelines:
Component ACGIH NIOSH OSHA-PELs
Water NA NA NA
Lithium Hydroxide Monohydrate ND ND ND
Engineering Controls:
Ventilation must be adequate to maintain the ambient workplace atmosphere below the exposure limit(s)
outlined in the MSDS. General room ventilation is satisfactory under anticipated use conditions.
Respiratory Protection:
Not required under anticipated use conditions.
Material Safety Data Sheet
Gen-Probe Incorporated Phone: 858-410-8000
10210 Genetic Center Drive Prepared: 3/10/05
San Diego, CA 92121-4362 Updated:
Page 4 of 7
Eye / Face Protection:
Wear appropriate safety glasses with side shields or chemical goggles as described by OSHA鈥檚 eye and
face protection regulations in 29CFR 1910.133 or European Standard EN166.
Skin Protection:
Wear chemical resistant gloves (such as latex or neoprene) and protective clothing to minimize skin
contact.
IX. Physical and Chemical Properties
Physical Appearance: Clear, colorless liquid
Odor: None
pH: 12
Specific Gravity: approx. 1
Water Solubility: Soluble
Melting Point: ND
Freezing Point ND
Boiling Point: ND
Vapor Pressure: ND
Vapor Density: ND
Percent Volatiles by Volume: ND
Viscosity: ND
Molecular Weight: ND
X. Stability and Reactivity
Chemical Stability:
Stable
Conditions to Avoid:
None
Materials / Chemicals to Be Avoided:
Strong oxidizing agents, acids, and metal nitrates.
Hazardous Decomposition Products:
Thermal decomposition may produce nitrogen oxides and sodium oxides.
Material Safety Data Sheet
Gen-Probe Incorporated Phone: 858-410-8000
10210 Genetic Center Drive Prepared: 3/10/05
San Diego, CA 92121-4362 Updated:
Page 5 of 7
Hazardous Polymerization:
Will not occur.
XI. Toxicological Information
Carcinogenicity:
NTP: NO
IARC: NO
OSHA: NO
Acute Dermal Toxicity:
ND
Acute Oral Toxicity:
ND
Acute Inhalation Toxicity:
For Lithium Hydroxide: 960 mg/m3/4H (rat) LC50
Chronic Toxicity:
Mutagenicity: ND
Reproductive effects: ND
XII. Ecological Information
Ecotoxicological Information:
Not Determined
XIII. Disposal Considerations
Waste Disposal Method:
Discard any product, residue, disposable container or liner in full compliance with national regulations.
Container Handling and Disposal:
Dispose of container and unused contents in accordance with national regulations.
XIV. Transportation Information
Shipping Name:
Lithium Hydroxide, solution
Proper Shipping Name
8
ADR/RID/IMO/ICAO Hazard Class
/US DOT
UN 2679
ID Number
II
Packaging Group
Material Safety Data Sheet
Gen-Probe Incorporated Phone: 858-410-8000
10210 Genetic Center Drive Prepared: 3/10/05
San Diego, CA 92121-4362 Updated:
Page 6 of 7
XV. Regulatory Information
U.S. Federal Regulations:
SARA Title III Hazard Classes:
Fire Hazard: No
Reactive Hazard: No
Release of Pressure: No
Acute Health Hazard: Yes
Chronic Health Hazard: Yes
TSCA
All components of this product are on the TSCA inventory or are not required to be listed.
Other Regulations:
U.S. State
None
European/International Regulations
Risk Phrases:
R 35 Causes severe burns
Safety Phrases:
S1/2 Keep locked up and out of the reach of children
S20 In case of contact with eyes, rinse immediately with plenty of water and seek
medical advice
S37/39 Wear suitable gloves and eye/face protection
S45 In case of accident or sickness, seek medical advice immediately and show this
container or label
EU Hazard Symbol:
C: Corrosive
XVI. Other Information
National Paint & Coating Hazardous Materials Identification System 鈥? HMIS(R):
Health Hazard: 3
Flammability: 0
Reactivity: 0
Material Safety Data Sheet
Gen-Probe Incorporated Phone: 858-410-8000
10210 Genetic Center Drive Prepared: 3/10/05
San Diego, CA 92121-4362 Updated:
Page 7 of 7
Key Legend Information:
N/A 鈥? Not Applicable
ND 鈥? Not Determined
ACGIH 鈥? American Conference of Governmental Industrial Hygienists
OSHA 鈥? Occupational Safety and Health Administration
TLV 鈥? Threshold Limit Value
PEL 鈥? Permissible Exposure Limit
TWA 鈥? Time Weighted Average
STEL 鈥? Short Term Exposure Limit
NTP 鈥? National Toxicology Program
IARC 鈥? International Agency for Research on Cancer
The information contained herein is based on the data available to us and is believed to be
correct. However Gen Probe Incorporated makes no warranty, expressed or implied regarding the
accuracy of this data or the results to be obtained from the use thereof.
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