PARACETAMOL 1330
November 1998
Acetaminophen
CAS No: 103-90-2
4-Hydroxyacetanilide
RTECS No: AE4200000
p-Acetylaminophenol
UN No:
C8H9NO2 / HOC6H4NHCOCH3
EC No:
Molecular mass: 151.2
TYPES OF
ACUTE HAZARDS/SYMPTOMS PREVENTION FIRST AID/FIRE FIGHTING
HAZARD/
EXPOSURE
Combustible. NO open flames. Powder, alcohol-resistant foam,
FIRE
water spray, carbon dioxide.
EXPLOSION
EXPOSURE PREVENT DISPERSION OF DUST!
See Notes. Local exhaust or breathing Fresh air, rest.
Inhalation
protection.
Protective gloves. Rinse skin with plenty of water or
Skin
shower.
Safety spectacles, or eye protection First rinse with plenty of water for
Eyes
in combination with breathing several minutes (remove contact
protection. lenses if easily possible), then take
to a doctor.
Abdominal pain. Diarrhoea. Do not eat, drink, or smoke during Rinse mouth. Induce vomiting
Ingestion
Drowsiness. Nausea. work. (ONLY IN CONSCIOUS
Unconsciousness. Vomiting. PERSONS!). Give plenty of water
to drink. Refer for medical
attention.
SPILLAGE DISPOSAL PACKAGING & LABELLING
Sweep spilled substance into containers. Do NOT Symbol
let this chemical enter the environment. (Extra R:
personal protection: P2 filter respirator for harmful S:
particles).
EMERGENCY RESPONSE STORAGE
Prepared in the context of cooperation between the International
IPCS Programme on Chemical Safety and the European Commission
International 漏 IPCS 1999
Programme on
Chemical Safety SEE IMPORTANT INFORMATION ON THE BACK.
1330 PARACETAMOL
IMPORTANT DATA
Physical State; Appearance Routes of Exposure
COLOURLESS CRYSTALS OR CRYSTALLINE POWDER The substance can be absorbed into the body by ingestion.
Chemical Dangers Inhalation Risk
The substance decomposes on heating above 45C. Evaporation at 20C is negligible; a harmful concentration of
airborne particles can, however, be reached quickly on
spraying or when dispersed, especialy if powdered.
Occupational Exposure Limits
TLV not established. MAK not established.
Effects of Short-term Exposure
The substance may cause effects on the liver and kidney,
resulting in liver impairment and kidney impairment only in
case of large amount ingested. The effects may be delayed.
Medical observation is indicated. See Notes.
Effects of Long-term or Repeated Exposure
The substance may have effects on the kidneys and liver,
resulting in impaired functions. May cause genetic damage in
humans.
PHYSICAL PROPERTIES
Boiling point: 500C Solubility in water, g/100 ml at 20C: 1.4
Melting point: 169-170C Octanol/water partition coefficient as log Pow: 0.49
ENVIRONMENTAL DATA
The substance is toxic to aquatic organisms.
NOTES
Temperature of decomposition unknown in literature. Health effects of exposure by inhalation to the substance have not been
investigated. Use of alcoholic beverages enhances the harmful effect. The symptoms of acute intoxications do not become
manifest until some 24-48 h to 3-4 days after ingestion of toxic doses. APAP, Panadol, Tempra, Tylenol are trade names.
ADDITIONAL INFORMATION
Neither the EC nor the IPCS nor any person acting on behalf of the EC or the IPCS is responsible
LEGAL NOTICE
漏 IPCS 1999
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