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Material Safety Data Sheet
DMSO (DIMETHYL SULFOXIDE)
1: Chemical Product and Company Identification
Product Name: DMSO (DIMETHYL SULFOXIDE)
Catalog Code: 705299, 705301
Contact information:
CAS#: 67鈭?68鈭?5
bioWORLD
RTECS: PV6210000 4150 Tuller Rd
Suite 228, Dublin, OH 43017, USA
TSCA: TSCA 8(b) inventory : Dimethyl sulfoxide.
For information, call: 614-792-8680
CI#: Not available. Fax Number: 614-792-8685
Order Online:www.bio-world.com
Synonym: A 10846; Deltan; Demeso; Demasorb; Demavet;
E-mail : save@bio-world.com
Demsodrox; Dermasorb; Dimethyl sulfoxide; Dimethyl sulphoxide;
Dimexide; Dipirartril-tropico; DMS-70; DMS-90; DMSO; Dolicur;
Domoso; Dromisol; Durasorb; Gamasol 90; Hyadur; Infiltrina; M In Case of a chemical emergency, call CHEMTREC
176; Methane, sulfinylbis-; Methylsulfinylmethane; NSC-763; (24 hours a day) at 1-800-424-9300
Rimso-50; Somipront; SQ 9453; Sulfinylbis(methane); Syntexan;
Topsym. For non-emergency assistance,call: 1-800-860-9729
Chemical Name: Dimethyl sulfoxide
Chemical Formula: (CH3)2SO
2: Composition and Information on Ingredients
Composition:
Name CAS# % by Weight
DMSO (DIMETHYL SULFOXIDE) 67鈭?68鈭?5 100
Toxicological Data on Ingredients:
LC50 (Inhalation, Rat): 40,250 mg/kg
LD50 (Oral, Rat): 3,300 mg/kg
LD50 (Oral, Rat): 14500 mg/kg
3: Hazards Identification
Potential Acute Health Effects: Combustible. Readily absorbed through skin.
Target organ(s): Eyes. Skin.
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Potential Chronic Health Effects:
CARCINOGENIC EFFECTS: Equivocal tumorigenic agent by RTECS criteria.
MUTAGENIC EFFECTS: Mutation in mammalian somatic cells.
TERATOGENIC EFFECTS: Teratogen.
DEVELOPMENTAL TOXICITY: Effects on Fertility: Abortion.
4: First Aid Measures
Eye Contact: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower
eyelids. Get medical aid.
Skin Contact: Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing
and shoes. Wash clothing before reuse.
Serious Skin Contact: Not available.
Inhalation: Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing
is difficult, give oxygen. Get medical aid. Do NOT use mouth鈭抰o鈭抦outh resuscitation.
Serious Inhalation: Not available.
Ingestion: Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious
and alert, rinse mouth and drink 2鈭?4 cupfuls of milk or water.
Serious Ingestion: Not available.
5: Fire and Explosion Data
Flammability of the Product: Combustible.
Auto-Ignition Temperature: 301 掳C
Flash Points: 87 掳C (188.6 掳F )
Flammable Limits: 3.5 - 42 %
Product of Combustion: Carbon monoxide, Carbon dioxide, Sulfur oxides.
Fire Hazards in Presence of Various Substances: Not available.
Explosion Hazards in Presence of Various Substances:
Not available.
Fire Fighting Media and Instructions:
SMALL FIRE: Dry chemical powder.
LARGE FIRE: Water spray. Carbon dioxide, dry chemical powder, or appropriate foam.
Special Remarks on Fire Hazards: Not available.
Special Remarks on Explosion Hazards: Not available.
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6: Accidental Release Measures
Small Spill: Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Do not flush
into a sewer. Clean up spills immediately, observing precautions in the Protective Equipment section. Provide ventilation.
Large Spill: Not available.
7: Handling and Storage
Precautions: Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.
Use with adequate ventilation. Wash clothing before reuse.
Storage: Keep away from heat, sparks, and flame. Store in a tightly closed container. Keep from contact with oxidizing
materials. Store in a cool, dry, well鈭抳entilated area away from incompatible substances.
8: Exposure Controls/Personal Protection
Engineering Controls: Safety shower and eye bath. Mechanical exhaust required.
Personal Protection: Eyes: Wear chemical splash goggles.
Skin: Wear appropriate protective gloves to prevent skin exposure.
Clothing: Wear appropriate protective clothing to prevent skin exposure. Respirators: A respiratory protection program that
meets OSHA's 29
Personal Protection in Case of a Large Spill: Splash goggles. Full suit. Boots. Dust respirator.Gloves.
Exposure Limits: Not available.
9: Physical and Chemical Properties
Physical State and Appearance: Liquid,Clear
Odor: slight odor 鈭捖爏ulfurous odor 鈭捖爂arlic鈭抣ike odor
Taste: Not available.
Molecular Weight: 78.13 g/mole
Color: Colorless.
pH(1% soln/water): Not available.
Boiling Point: 189 掳C
Melting Point: 18.4 掳C
Critical Temperature: Not available.
Specific Gravity: 1.1
Vapour Pressure: 0.42
Vapor Density: 2.7 (air=1)
Volatility: Not available.
Odor Threshold: Not available.
Water/Oil Dist. Coeff: Not available.
Ionicity (in Water): Not available.
Dispersion Properties: Not available.
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Solubility: Soluble in water, alcohol and ethyl ethers.
10: Stability and Reactivity Data
Stability: Stable.
Instability Temperature: Not available.
Conditions of Instability: Excess heat, moisture.
Incompatibility with various substances: Acid chlorides, Phosphorus halides, Strong acids, Strong oxidizing agents,
Strong reducing agents.
Corrosivity: Not available.
Special Remarks on Reactivity: Methyl sulfoxide (DMSO) undergoes a violent exothermic reaction on mixing with copper
wool and trichloroacetic acid.
On mixing with potassium permanganate it will flash instantaneously.
It reacts violently with: acid halides, cyanuric chloride
Special Remarks on Corrosivity: Not available.
Polymerization: Will not occur.
11:Toxicological Information
Routes of Entry: Skin contact. Eye contact. Ingestion. Inhalation.
Toxicity to Animals:
LC50 (Inhalation, Rat): 40,250 mg/kg
LD50 (Oral, Rat): 3,300 mg/kg
LD50 (Skin, Rabbit): > 5,000 mg/kg
LD50 (Oral, Rat): 14500 mg/kg
LD50 (Skin, Rat): 40000 mg/kg
LD50 (Intraperitoneal, Rat): 8200 mg/kg
LD50 (Subcutaneous, Rat): 12 g/kg
LD50 (Intravenous, Rat): 5360 mg/kg
LD50 (Oral, Mouse): 7920 mg/kg
LD50 (Skin, Mouse): 50000 mg/kg
LD50 (Intraperitoneal, Mouse): 2500 mg/kg
LD50 (Subcutaneous, Mouse): 14 g/kg
LD50 (Intravenous, Mouse): 3100 mg/kg
Chronic Effects on Humans: Equivocal tumorigenic agent by RTECS criteria.
Specific Developmental Abnormalities: Central nervous system, Musculoskeletal system.
Mutation in mammalian somatic cells.
Effects on Fertility: Abortion.
Other Toxic Effects on Humans: Skin Contact: May cause skin irritation.
Skin Absorption: May be harmful if absorbed through the skin. Readily absorbed through skin.
Eye Contact: May cause eye irritation.
Inhalation: Material may be irritating to mucous membranes and upper respiratory tract. May be harmful if inhaled.
Ingestion: May be harmful if swallowed.
Special Remarks on Toxicity to Animals: Not available.
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Special Remarks on Chronic Effects on Humans: Not available.
Special Remarks on other Toxic Effects on Humans: Avoid contact with DMSO solutions containing toxic materials or
materials with unknown toxicological properties. Dimethyl sulfoxide is readily absorbed through skin and may carry such
materials into the body.
12: Ecological Information
Ecotoxicity: LC50 Fish (Onchorhynchus mykiss (Rainbow trout)): 35,000 mg/l/96H
EC50 Daphnia (Daphnia pulex): 27,500 mg/l
EC50 Algae(Lepomis macrochirus (Bluegill)): > 400,000 mg/l/96H
LC50 Fish (Pimephales promelas (Fathead minnow)): 34,000 mg/l/96H
BOD5 and COD: Not available.
Product of Biodegradation: Not available.
Toxicity of the Products of Biodegradation: Not available.
Special Remarks on the Products of Biodegradation: Not available.
13: Disposal Considerations
Waste Disposal: Contact a licensed professional waste disposal service to dispose of this material. This combustible
material may be burned in a chemical incinerator equipped with an afterburner and scrubber. Observe all federal, state, and
local environmental regulations.
14: Transport Information
DOT Classification: Class: COMBUSTIBLE LIQUID
Identification: UN#: NA1993
Packing Group: III
Special Provisions for Transport: Not available.
15: Other Regulatory Information
Federal and State Regulations: TSCA 8(b) inventory : Dimethyl sulfoxide.
Other Regulations: Not available.
Other Classifications:
WHMIS(Canada): This product has a WHMIS classification of D2B.
DSCL(EEC): Not available.
HMIS(U.S.A):
Health Hazard: 0
Fire Hazard: 2
Reactivity: 1
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Personal Protection:
National Fire Protection Association (U.S.A):
Health: 0
Flammability: 2
Reactivity: 1
Specific hazard:
Protective Equipment: Gloves. Lab coat. Dust respirator. Safety goggles.
16: Other Information
References: Not available.
Other Special Considerations: Not available.
Created: 15/06/2006 4:33:06 PM
Last Updated: 07/08/2006 11:01:37 AM
Disclaimer
This product is offered by bioWORLD for research, laboratory or further manufacturing use. Not for human use or
consumption.
The information above is believed to be accurate and represents the best information currently available to us. However,we
make no warranty of merchantability or any other warranty, express or implied, with respect to such information, and we
assume no liability resulting from its use. Users should make their own investigations to determine the suitability of the
information for their particular purposes.In no event shall Bio-World.com be liable for any claims, losses, or damages of any
third party or for lost profits or any special, indirect,incidental,consequential or exemplary damages, howsoever arising,
even if Bio-World.com has been advised of the possibility of such damages.
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