PHENOLPHTHALEIN Page 1 of 7
PHENOLPHTHALEIN
MSDS Number: P2015 --- Effective Date: 12/08/96
1. Product Identification
Synonyms: 3,3-bis(p-hydroxyphenyl) phthalide; 3,3-bis(4-hydroxyphenyl)-1(3H)-
isobenzofuranore
CAS No.: 77-09-8
Molecular Weight: 318.33
Chemical Formula: C20H14O4
Product Codes: J.T. Baker: 2870, 2872 Mallinckrodt: 6600
2. Composition/Information on Ingredients
Ingredient CAS No Percent Hazardous
--------------------------------------- ------------ ------- ---------
Phenolphthalein 77-09-8 100% Yes
3. Hazards Identification
Emergency Overview
--------------------------
WARNING! HARMFUL IF SWALLOWED.
J.T. Baker SAF-T-DATA(tm) Ratings (Provided here for your convenience)
-----------------------------------------------------------------------------------------------------------
http://www.jtbaker.com/msds/p2015.htm 12/31/98
PHENOLPHTHALEIN Page 2 of 7
Health Rating: 1 - Slight
Flammability Rating: 1 - Slight
Reactivity Rating: 1 - Slight
Contact Rating: 1 - Slight
Lab Protective Equip: GOGGLES; LAB COAT
Storage Color Code: Orange (General Storage)
-----------------------------------------------------------------------------------------------------------
Potential Health Effects
----------------------------------
Inhalation:
Nuisance dust. May cause coughing and sneezing.
Ingestion:
Cathartic. Very active, even in small amounts (30-100 mg). May cause purging, collapse,
and fall of blood pressure or an itching skin rash that can become ulcerous. Other
systemic effects are not well known.
Skin Contact:
Not classified as an irritant but may be absorbed via moist or oily surfaces. Symptoms
may resemble those from ingestion exposure.
Eye Contact:
Slight irritant.
Chronic Exposure:
No information found.
Aggravation of Pre-existing Conditions:
Persons with pre-existing skin disorders or impaired respiratory function may be more
susceptible to the effects of the substance.
4. First Aid Measures
Inhalation:
Remove to fresh air. Get medical attention for any breathing difficulty.
Ingestion:
Induce vomiting immediately as directed by medical personnel. Never give anything by
mouth to an unconscious person. Get medical attention.
Skin Contact:
Wash exposed area with soap and water. Get medical advice if irritation develops.
http://www.jtbaker.com/msds/p2015.htm 12/31/98
PHENOLPHTHALEIN Page 3 of 7
Eye Contact:
Immediately flush eyes with plenty of water for at least 15 minutes, lifting upper and
lower eyelids occasionally. Get medical attention if irritation persists.
5. Fire Fighting Measures
Fire:
As with most organic solids, fire is possible at elevated temperatures or by contact with
an ignition source.
Explosion:
Fine dust dispersed in air in sufficient concentrations, and in the presence of an ignition
source is a potential dust explosion hazard.
Fire Extinguishing Media:
Dry chemical, foam or carbon dioxide.
Special Information:
In the event of a fire, wear full protective clothing and NIOSH-approved self-contained
breathing apparatus with full facepiece operated in the pressure demand or other positive
pressure mode.
6. Accidental Release Measures
Remove all sources of ignition. Ventilate area of leak or spill. Wear appropriate personal
protective equipment as specified in Section 8. Spills: Clean up spills in a manner that
does not disperse dust into the air. Use non-sparking tools and equipment. Reduce
airborne dust and prevent scattering by moistening with water. Pick up spill for recovery
or disposal and place in a closed container.
7. Handling and Storage
Keep in a tightly closed container, stored in a cool, dry, ventilated area. Protect against
physical damage. Containers of this material may be hazardous when empty since they
retain product residues (dust, solids); observe all warnings and precautions listed for the
product.
8. Exposure Controls/Personal Protection
Airborne Exposure Limits:
None established.
http://www.jtbaker.com/msds/p2015.htm 12/31/98
PHENOLPHTHALEIN Page 4 of 7
Ventilation System:
A system of local and/or general exhaust is recommended to keep employee exposures as
low as possible. Local exhaust ventilation is generally preferred because it can control the
emissions of the contaminant at its source, preventing dispersion of it into the general
work area. Please refer to the ACGIH document, Industrial Ventilation, A Manual of
Recommended Practices, most recent edition, for details.
Personal Respirators (NIOSH Approved):
For conditions of use where exposure to the dust or mist is apparent, a half-face dust/mist
respirator may be worn. For emergencies or instances where the exposure levels are not
known, use a full-face positive-pressure, air-supplied respirator. WARNING: Air-
purifying respirators do not protect workers in oxygen-deficient atmospheres.
Skin Protection:
Wear protective gloves and clean body-covering clothing.
Eye Protection:
Use chemical safety goggles. Maintain eye wash fountain and quick-drench facilities in
work area.
9. Physical and Chemical Properties
Appearance:
White to pale yellow crystals.
Odor:
Odorless.
Solubility:
Slightly soluble in water.
Density:
1.299
pH:
No information found.
% Volatiles by volume @ 21C (70F):
No information found.
Boiling Point:
Not applicable.
Melting Point:
258 - 262C (496 - 504F)
Vapor Density (Air=1):
http://www.jtbaker.com/msds/p2015.htm 12/31/98
PHENOLPHTHALEIN Page 5 of 7
No information found.
Vapor Pressure (mm Hg):
No information found.
Evaporation Rate (BuAc=1):
No information found.
10. Stability and Reactivity
Stability:
Stable under ordinary conditions of use and storage.
Hazardous Decomposition Products:
Carbon dioxide and carbon monoxide may form when heated to decomposition.
Hazardous Polymerization:
Will not occur.
Incompatibilities:
Strong oxidizing agents.
Conditions to Avoid:
Incompatibles.
11. Toxicological Information
No LD50/LC50 information found relating to normal routes of occupational exposure.
Investigated as a tumorigen and mutagen.
--------\Cancer Lists\------------------------------------------------------
---NTP Carcinogen---
Ingredient Known Anticipated IARC Category
------------------------------------ ----- ----------- -------------
Phenolphthalein (77-09-8) No No None
12. Ecological Information
Environmental Fate:
No information found.
Environmental Toxicity:
No information found.
http://www.jtbaker.com/msds/p2015.htm 12/31/98
PHENOLPHTHALEIN Page 6 of 7
13. Disposal Considerations
Whatever cannot be saved for recovery or recycling should be managed in an appropriate
and approved waste disposal facility. Processing, use or contamination of this product
may change the waste management options. State and local disposal regulations may
differ from federal disposal regulations. Dispose of container and unused contents in
accordance with federal, state and local requirements.
14. Transport Information
Not regulated.
15. Regulatory Information
--------\Chemical Inventory Status - Part 1\---------------------------------
Ingredient TSCA EC Japan Australia
----------------------------------------------- ---- --- ----- ---------
Phenolphthalein (77-09-8) Yes Yes Yes Yes
--------\Chemical Inventory Status - Part 2\---------------------------------
--Canada--
Ingredient Korea DSL NDSL Phil.
----------------------------------------------- ----- --- ---- -----
Phenolphthalein (77-09-8) Yes Yes No Yes
--------\Federal, State & International Regulations - Part 1\----------------
-SARA 302- ------SARA 313------
Ingredient RQ TPQ List Chemical Catg.
----------------------------------------- --- ----- ---- --------------
Phenolphthalein (77-09-8) No No No No
--------\Federal, State & International Regulations - Part 2\----------------
-RCRA- -TSCA-
Ingredient CERCLA 261.33 8(d)
----------------------------------------- ------ ------ ------
Phenolphthalein (77-09-8) No No No
Chemical Weapons Convention: No TSCA 12(b): No CDTA: No
SARA 311/312: Acute: Yes Chronic: No Fire: No Pressure: No
Reactivity: No (Pure / Solid)
Australian Hazchem Code: No information found.
Poison Schedule: No information found.
http://www.jtbaker.com/msds/p2015.htm 12/31/98
PHENOLPHTHALEIN Page 7 of 7
WHMIS:
This MSDS has been prepared according to the hazard criteria of the Controlled Products
Regulations (CPR) and the MSDS contains all of the information required by the CPR.
16. Other Information
NFPA Ratings: Health: 1 Flammability: 1 Reactivity: 0
Label Hazard Warning:
WARNING! HARMFUL IF SWALLOWED.
Label Precautions:
Wash thoroughly after handling.
Label First Aid:
If swallowed, induce vomiting immediately as directed by medical personnel. Never give
anything by mouth to an unconscious person. Get medical attention.
Product Use:
Laboratory Reagent.
Revision Information:
Pure. New 16 section MSDS format, all sections have been revised.
Disclaimer:
***************************************************************************************
Mallinckrodt Baker, Inc. provides the information contained herein in good faith
but makes no representation as to its comprehensiveness or accuracy. This
document is intended only as a guide to the appropriate precautionary handling of
the material by a properly trained person using this product. Individuals receiving
the information must exercise their independent judgment in determining its
appropriateness for a particular purpose. MALLINCKRODT BAKER, INC.
MAKES NO REPRESENTATIONS OR WARRANTIES, EITHER EXPRESS OR
IMPLIED, INCLUDING WITHOUT LIMITATION ANY WARRANTIES OF
MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE WITH
RESPECT TO THE INFORMATION SET FORTH HEREIN OR THE PRODUCT
TO WHICH THE INFORMATION REFERS. ACCORDINGLY,
MALLINCKRODT BAKER, INC. WILL NOT BE RESPONSIBLE FOR
DAMAGES RESULTING FROM USE OF OR RELIANCE UPON THIS
INFORMATION.
***************************************************************************************
Prepared by: Strategic Services Division
Phone Number: (314) 539-1600 (U.S.A.)
http://www.jtbaker.com/msds/p2015.htm 12/31/98
|