ACETONE
Chemwatch Material Safety Data Sheet
For Workplace - Small Volume Use Only. CHEMWATCH 1090
Issue Date: 26-Mar-2007 Version No:1
NC317TLP CD 2007/3 Page 1 of 16
Section 1 - CHEMICAL PRODUCT AND COMPANY IDENTIFICATION
PRODUCT NAME
ACETONE
SYNONYMS
C3-H6-O, CH3COCH3, propanone, "pyroacetic acid", "pyroacetic ether", 2-propanone, 2
-propanone, beta-ketopropane, "methyl ketone", propan-2-one, propan-2-one, "dimethyl
ketone", "ketone, dimethyl ketone propane", "dimethyl formaldehyde"
PROPER SHIPPING NAME
ACETONE
PRODUCT USE
Solvent for fats, oils, waxes, resins, rubber, plastics, lacquers. Used in manufacture of
methyl isobutyl ketone, mesityl oxide, acetic acid, diacetone alcohol, isoprene. Used in
solvent extraction processes. Solvent in the manufacture of explosives and rayon.
Component of adhesives, glues, cleaning solvents, lacquer thinners, nail polish, paint
removers. Storing acetylene gas (takes up about 24 times its volume of the gas). Purifying
paraffin and biomedical hardening and dehydrating tissues. Minor food additive, permitted
in USA.
SUPPLIER
Company: Quantum Chemicals Pty Ltd
Address:
70 Quantum Close
Quantum Industrial Park
Dandenong South VIC 3175
Australia
Telephone: 1300 782 688
Emergency Tel: 1300 131 001
Fax: 1300 782 699
HAZARD RATINGS
ACETONE
Chemwatch Material Safety Data Sheet
For Workplace - Small Volume Use Only. CHEMWATCH 1090
Issue Date: 26-Mar-2007 Version No:1
NC317TLP CD 2007/3 Page 2 of 16
Section 1 - CHEMICAL PRODUCT AND COMPANY IDENTIFICATION
Flammability
Toxicity
Body Contact
Reactivity
Chronic
SCALE: Min/Nil=0 Low=1 Moderate=2 High=3 Extreme=4
Section 2 - HAZARDS IDENTIFICATION
STATEMENT OF HAZARDOUS NATURE
HAZARDOUS SUBSTANCE. DANGEROUS GOODS. According to the Criteria of NOHSC,
and the ADG Code.
POISONS SCHEDULE
S5, NZS4
RISK SAFETY
Highly flammable. Keep away from sources of ignition. No smoking.
Irritating to eyes. Do not breathe gas/ fumes/ vapour/ spray.
HARMFUL - May cause lung damage if swallowed. Avoid contact with eyes.
Repeated exposure may cause skin dryness and Wear suitable protective clothing.
cracking.
Vapours may cause drowsiness and dizziness. Use only in well ventilated areas.
Inhalation skin contact and/or ingestion may Keep container in a well ventilated place.
produce health damage*.
Cumulative effects may result following Do not empty into drains.
exposure*.
May produce discomfort of the respiratory system To clean the floor and all objects contaminated
and skin*. by this material use water.
* (limited evidence). Keep container tightly closed.
Keep away from food drink and animal feeding
stuffs.
Take off immediately all contaminated clothing.
In case of contact with eyes rinse with plenty
of water and contact Doctor or Poisons
Information Centre.
If swallowed IMMEDIATELY contact Doctor or
Poisons Information Centre (show this container
or label).
This material and its container must be disposed
of as hazardous waste.
Section 3 - COMPOSITION / INFORMATION ON INGREDIENTS
NAME CAS RN %
acetone 67-64-1 95-99.5
ACETONE
Chemwatch Material Safety Data Sheet
For Workplace - Small Volume Use Only. CHEMWATCH 1090
Issue Date: 26-Mar-2007 Version No:1
NC317TLP CD 2007/3 Page 3 of 16
Section 4 - FIRST AID MEASURES
SWALLOWED
路 For advice, contact a Poisons Information Centre or a doctor at once.
路 Urgent hospital treatment is likely to be needed.
路 If swallowed do NOT induce vomiting.
路 If vomiting occurs, lean patient forward or place on left side (head-down position, if
possible) to maintain open airway and prevent aspiration.
路 Observe the patient carefully.
路 Never give liquid to a person showing signs of being sleepy or with reduced awareness;
i.e. becoming unconscious.
路 Give water to rinse out mouth, then provide liquid slowly and as much as casualty can
comfortably drink.
路 Transport to hospital or doctor without delay.
EYE
If this product comes in contact with the eyes:
路 Wash out immediately with fresh running water.
路 Ensure complete irrigation of the eye by keeping eyelids apart and away from eye and
moving the eyelids by occasionally lifting the upper and lower lids.
路 If pain persists or recurs seek medical attention.
路 Removal of contact lenses after an eye injury should only be undertaken by skilled
personnel.
SKIN
If skin contact occurs:
路 Immediately remove all contaminated clothing, including footwear.
路 Flush skin and hair with running water (and soap if available).
路 Seek medical attention in event of irritation.
INHALED
路 If fumes or combustion products are inhaled remove from contaminated area.
路 Lay patient down. Keep warm and rested.
路 Prostheses such as false teeth, which may block airway, should be removed, where
possible, prior to initiating first aid procedures.
路 Apply artificial respiration if not breathing, preferably with a demand valve
resuscitator, bag-valve mask device, or pocket mask as trained. Perform CPR if necessary.
路 Transport to hospital, or doctor.
NOTES TO PHYSICIAN
Any material aspirated during vomiting may produce lung injury. Therefore emesis should
not be induced mechanically or pharmacologically. Mechanical means should be used if it
is considered necessary to evacuate the stomach contents; these include gastric lavage
after endotracheal intubation. If spontaneous vomiting has occurred after ingestion, the
patient should be monitored for difficult breathing, as adverse effects of aspiration
into the lungs may be delayed up to 48 hours.
For acute or short term repeated exposures to acetone:
路 Symptoms of acetone exposure approximate ethanol intoxication.
路 About 20% is expired by the lungs and the rest is metabolised. Alveolar air half-life
is about 4 hours following two hour inhalation at levels near the Exposure Standard; in
overdose, saturable metabolism and limited clearance, prolong the elimination half-life
to 25-30 hours.
路 There are no known antidotes and treatment should involve the usual methods of
decontamination followed by supportive care.
[Ellenhorn and Barceloux: Medical Toxicology]
Management:
Measurement of serum and urine acetone concentrations may be useful to monitor the
severity of ingestion or inhalation.
Inhalation Management:
ACETONE
Chemwatch Material Safety Data Sheet
For Workplace - Small Volume Use Only. CHEMWATCH 1090
Issue Date: 26-Mar-2007 Version No:1
NC317TLP CD 2007/3 Page 4 of 16
Section 4 - FIRST AID MEASURES
路 Maintain a clear airway, give humidified oxygen and ventilate if necessary.
路 If respiratory irritation occurs, assess respiratory function and, if necessary,
perform chest X-rays to check for chemical pneumonitis.
路 Consider the use of steroids to reduce the inflammatory response.
路 Treat pulmonary oedema with PEEP or CPAP ventilation.
Dermal Management:
路 Remove any remaining contaminated clothing, place in double sealed, clear bags, label
and store in secure area away from patients and staff.
路 Irrigate with copious amounts of water.
路 An emollient may be required.
Eye Management:
路 Irrigate thoroughly with running water or saline for 15 minutes.
路 Stain with fluorescein and refer to an ophthalmologist if there is any uptake of the
stain.
Oral Management:
路 No GASTRIC LAVAGE OR EMETIC
路 Encourage oral fluids.
Systemic Management:
路 Monitor blood glucose and arterial pH.
路 Ventilate if respiratory depression occurs.
路 If patient unconscious, monitor renal function.
路 Symptomatic and supportive care.
The Chemical Incident Management Handbook:
Guy's and St. Thomas' Hospital Trust, 2000
BIOLOGICAL EXPOSURE INDEX
These represent the determinants observed in specimens collected from a healthy worker
exposed at the Exposure Standard (ES or TLV):
Determinant Sampling Time Index Comments
Acetone in urine End of shift 50 mg/L NS
NS: Non-specific determinant; also observed after exposure to other material.
Section 5 - FIRE FIGHTING MEASURES
EXTINGUISHING MEDIA
路 Alcohol stable foam.
路 Dry chemical powder.
路 BCF (where regulations permit).
路 Carbon dioxide.
路 Water spray or fog - Large fires only.
FIRE FIGHTING
路 Alert Fire Brigade and tell them location and nature of hazard.
路 May be violently or explosively reactive.
路 Wear breathing apparatus plus protective gloves.
路 Prevent, by any means available, spillage from entering drains or water course.
路 Consider evacuation (or protect in place).
路 Fight fire from a safe distance, with adequate cover.
路 If safe, switch off electrical equipment until vapour fire hazard removed.
路 Use water delivered as a fine spray to control the fire and cool adjacent area.
ACETONE
Chemwatch Material Safety Data Sheet
For Workplace - Small Volume Use Only. CHEMWATCH 1090
Issue Date: 26-Mar-2007 Version No:1
NC317TLP CD 2007/3 Page 5 of 16
Section 5 - FIRE FIGHTING MEASURES
路 Avoid spraying water onto liquid pools.
路 Do not approach containers suspected to be hot.
路 Cool fire exposed containers with water spray from a protected location.
路 If safe to do so, remove containers from path of fire.
FIRE/EXPLOSION HAZARD
路 Liquid and vapour are highly flammable.
路 Severe fire hazard when exposed to heat, flame and/or oxidisers.
路 Vapour may travel a considerable distance to source of ignition.
路 Heating may cause expansion or decomposition leading to violent rupture of containers.
路 On combustion, may emit toxic fumes of carbon monoxide (CO).
Combustion products include: carbon dioxide (CO2), other pyrolysis products typical of
burning organic material.
FIRE INCOMPATIBILITY
Avoid contamination with oxidising agents i.e. nitrates, oxidising acids, chlorine
bleaches, pool chlorine etc. as ignition may result.
HAZCHEM: 2[Y]E
Section 6 - ACCIDENTAL RELEASE MEASURES
EMERGENCY PROCEDURES
MINOR SPILLS
路 Remove all ignition sources.
路 Clean up all spills immediately.
路 Avoid breathing vapours and contact with skin and eyes.
路 Control personal contact by using protective equipment.
路 Contain and absorb small quantities with vermiculite or other absorbent material.
路 Wipe up.
路 Collect residues in a flammable waste container.
MAJOR SPILLS
Chemical Class: ketones
For release onto land: recommended sorbents listed in order of priority.
SORBENT TYPE RANK APPLICATION COLLECTION LIMITATIONS
LAND SPILL - SMALL
cross- linked 1 shovel shovel R, W, SS
polymer -
particulate
cross- linked 1 throw pitchfork R, DGC, RT
polymer - pillow
sorbent clay - 2 shovel shovel R, I, P
particulate
wood fiber - 3 throw pitchfork R, P, DGC, RT
pillow
treated wood fiber 3 throw pitchfork DGC, RT
- pillow
foamed glass - 4 throw pitchfork R, P, DGC, RT
ACETONE
Chemwatch Material Safety Data Sheet
For Workplace - Small Volume Use Only. CHEMWATCH 1090
Issue Date: 26-Mar-2007 Version No:1
NC317TLP CD 2007/3 Page 6 of 16
Section 6 - ACCIDENTAL RELEASE MEASURES
pillow
LAND SPILL - MEDIUM
cross- linked 1 blower skiploader R, W, SS
polymer -
particulate
cross- linked 2 throw skiploader R, DGC, RT
polymer - pillow
sorbent clay - 3 blower skiploader R, I, P
particulate
polypropylene - 3 blower skiploader R, SS, DGC
particulate
expanded mineral - 4 blower skiploader R, I, W, P, DGC
particulate
polypropylene - 4 throw skiploader DGC, RT
mat
Legend
DGC: Not effective where ground cover is dense
R; Not reusable
I: Not incinerable
P: Effectiveness reduced when rainy
RT:Not effective where terrain is rugged
SS: Not for use within environmentally sensitive sites
W: Effectiveness reduced when windy
Reference: Sorbents for Liquid Hazardous Substance Cleanup and Control;
R.W Melvold et al: Pollution Technology Review No. 150: Noyes Data Corporation 1988.
路 Clear area of personnel and move upwind.
路 Alert Fire Brigade and tell them location and nature of hazard.
路 May be violently or explosively reactive.
路 Wear breathing apparatus plus protective gloves.
路 Prevent, by any means available, spillage from entering drains or water course.
路 Consider evacuation (or protect in place).
路 No smoking, naked lights or ignition sources.
路 Increase ventilation.
路 Stop leak if safe to do so.
路 Water spray or fog may be used to disperse /absorb vapour.
路 Contain spill with sand, earth or vermiculite.
路 Use only spark-free shovels and explosion proof equipment.
路 Collect recoverable product into labelled containers for recycling.
路 Absorb remaining product with sand, earth or vermiculite.
路 Collect solid residues and seal in labelled drums for disposal.
路 Wash area and prevent runoff into drains.
路 If contamination of drains or waterways occurs, advise emergency services.
EMERGENCY RESPONSE PLANNING GUIDELINES (ERPG)
The maximum airborne concentration below which it is believed that nearly all individuals could be exposed
for up to one hour WITHOUT experiencing or developing
life-threatening health effects is:
acetone 8500 ppm
irreversible or other serious effects or symptoms which could impair an individual's ability to take
protective action is:
ACETONE
Chemwatch Material Safety Data Sheet
For Workplace - Small Volume Use Only. CHEMWATCH 1090
Issue Date: 26-Mar-2007 Version No:1
NC317TLP CD 2007/3 Page 7 of 16
Section 6 - ACCIDENTAL RELEASE MEASURES
acetone 8500 ppm
other than mild, transient adverse effects without perceiving a clearly defined odour is:
acetone 1000 ppm
The threshold concentration below which most people will experience no appreciable risk of health effects:
acetone 1000 ppm
American Industrial Hygiene Association (AIHA)
Ingredients considered according to the following cutoffs
Very Toxic (T+) >= 0.1% Toxic (T) >= 3.0%
R50 >= 0.25% Corrosive (C) >= 5.0%
R51 >= 2.5%
else >= 10%
where percentage is percentage of ingredient found in the mixture
Personal Protective Equipment advice is contained in Section 8 of the MSDS.
Section 7 - HANDLING AND STORAGE
PROCEDURE FOR HANDLING
路 Avoid all personal contact, including inhalation.
路 Wear protective clothing when risk of exposure occurs.
路 Use in a well-ventilated area.
路 Prevent concentration in hollows and sumps.
路 DO NOT enter confined spaces until atmosphere has been checked.
路 Avoid smoking, naked lights, heat or ignition sources.
路 When handling, DO NOT eat, drink or smoke.
路 Vapour may ignite on pumping or pouring due to static electricity.
路 DO NOT use plastic buckets.
路 Earth and secure metal containers when dispensing or pouring product.
路 Use spark-free tools when handling.
路 Avoid contact with incompatible materials.
路 Keep containers securely sealed.
路 Avoid physical damage to containers.
路 Always wash hands with soap and water after handling.
路 Work clothes should be laundered separately.
路 Use good occupational work practice.
路 Observe manufacturer's storing and handling recommendations.
路 Atmosphere should be regularly checked against established exposure standards to
ensure safe working conditions.
DO NOT allow clothing wet with material to stay in contact with skin.
SUITABLE CONTAINER
路 Packing as supplied by manufacturer.
路 Plastic containers may only be used if approved for flammable liquid.
路 Check that containers are clearly labelled and free from leaks.
路 For low viscosity materials (i) : Drums and jerry cans must be of the non-removable
head type. (ii) : Where a can is to be used as an inner package, the can must have a
screwed enclosure.
路 For materials with a viscosity of at least 2680 cSt. (23 deg. C)
路 For manufactured product having a viscosity of at least 250 cSt. (23 deg. C)
路 Manufactured product that requires stirring before use and having a viscosity of at
least 20 cSt (25 deg. C)
(i) : Removable head packaging;
(ii) : Cans with friction closures and
(iii) : low pressure tubes and cartridges may be used.
ACETONE
Chemwatch Material Safety Data Sheet
For Workplace - Small Volume Use Only. CHEMWATCH 1090
Issue Date: 26-Mar-2007 Version No:1
NC317TLP CD 2007/3 Page 8 of 16
Section 7 - HANDLING AND STORAGE
路 Where combination packages are used, and the inner packages are of glass, there must be
sufficient inert cushioning material in contact with inner and outer packages
路 In addition, where inner packagings are glass and contain liquids of packing group I
there must be sufficient inert absorbent to absorb any spillage, unless the outer
packaging is a close fitting moulded plastic box and the substances are not incompatible
with the plastic.
STORAGE INCOMPATIBILITY
Avoid reaction with oxidising agents.
Acetone reacts violently with bromoform and chloroform in the presence
of alkalies or in contact with alkaline surfaces.
STORAGE REQUIREMENTS
路 Store in original containers in approved flame-proof area.
路 No smoking, naked lights, heat or ignition sources.
路 DO NOT store in pits, depressions, basements or areas where vapours may be trapped.
路 Keep containers securely sealed.
路 Store away from incompatible materials in a cool, dry well ventilated area.
路 Protect containers against physical damage and check regularly for leaks.
路 Observe manufacturer's storing and handling recommendations.
_____________________________________________________
SAFE STORAGE WITH OTHER CLASSIFIED CHEMICALS
+ X X X X +
_____________________________________________________
+: May be stored together
O: May be stored together with specific preventions
X: Must not be stored together
Section 8 - EXPOSURE CONTROLS / PERSONAL PROTECTION
EXPOSURE CONTROLS
Source Material TWA ppm TWA mg/m鲁 STEL ppm STEL mg/m鲁
_________ _________ _____ _____ _____ _____
Australia acetone (Acetone) 500 1185 1000 2375
Exposure
Standards
EMERGENCY EXPOSURE LIMITS
Material Revised IDLH Value (mg/m3) Revised IDLH Value (ppm)
acetone 2, 500 [LEL]
NOTES
Values marked LEL indicate that the IDLH was based on 10% of the lower explosive limit
for safety considerations even though the relevant toxicological data indicated that
irreversible health effects or impairment of escape existed only at higher
concentrations.
ODOUR SAFETY FACTOR (OSF)
OSF=38 (ACETONE)
MATERIAL DATA
Exposed individuals are reasonably expected to be warned, by smell, that the Exposure
Standard is being exceeded.
ACETONE
Chemwatch Material Safety Data Sheet
For Workplace - Small Volume Use Only. CHEMWATCH 1090
Issue Date: 26-Mar-2007 Version No:1
NC317TLP CD 2007/3 Page 9 of 16
Section 8 - EXPOSURE CONTROLS / PERSONAL PROTECTION
Odour Safety Factor (OSF) is determined to fall into either Class A or B.
The Odour Safety Factor (OSF) is defined as:
OSF= Exposure Standard (TWA) ppm/ Odour Threshold Value (OTV) ppm
Classification into classes follows:
Class OSF Description
A 550 Over 90% of exposed individuals
are aware by smell that the
Exposure Standard (TLV- TWA for
example) is being reached, even
when distracted by working
activities
B 26- 550 As " A" for 50- 90% of persons
being distracted
C 1- 26 As " A" for less than 50% of
persons being distracted
D 0.18- 1 10- 50% of persons aware of
being tested perceive by smell
that the Exposure Standard is
being reached
E <0.18 As " D" for less than 10% of
persons aware of being tested
.
Odour Threshold Value: 3.6 ppm (detection), 699 ppm (recognition)
Saturation vapour concentration: 237000 ppm @ 20 C
NOTE: Detector tubes measuring in excess of 40 ppm, are available.
Exposure at or below the recommended TLV-TWA is thought to protect the
worker against mild irritation associated with brief exposures and the
bioaccumulation, chronic irritation of the respiratory tract and headaches
associated with long-term acetone exposures. The NIOSH REL-TWA is
substantially lower and has taken into account slight irritation
experienced by volunteer subjects at 300 ppm. Mild irritation to
acclimatised workers begins at about 750 ppm - unacclimatised subjects
will experience irritation at about 350-500 ppm but acclimatisation can
occur rapidly. Disagreement between the peak bodies is based largely on
the view by ACGIH that widespread use of acetone, without evidence of
significant adverse health effects at higher concentrations, allows
acceptance of a higher limit.
Half-life of acetone in blood is 3 hours which means that no adjustment
for shift-length has to be made with reference to the standard 8 hour/day,
40 hours per week because body clearance occurs within any shift with low
potential for accumulation.
A STEL has been established to prevent excursions of acetone vapours that
could cause depression of the central nervous system.
PERSONAL PROTECTION
EYE
路 Safety glasses with side shields.
路 Chemical goggles.
路 Contact lenses may pose a special hazard; soft contact lenses may absorb and
concentrate irritants. A written policy document, describing the wearing of lens or
ACETONE
Chemwatch Material Safety Data Sheet
For Workplace - Small Volume Use Only. CHEMWATCH 1090
Issue Date: 26-Mar-2007 Version No:1
NC317TLP CD 2007/3 Page 10 of 16
Section 8 - EXPOSURE CONTROLS / PERSONAL PROTECTION
restrictions on use, should be created for each workplace or task. This should include a
review of lens absorption and adsorption for the class of chemicals in use and an account
of injury experience. Medical and first-aid personnel should be trained in their removal
and suitable equipment should be readily available. In the event of chemical exposure,
begin eye irrigation immediately and remove contact lens as soon as practicable. Lens
should be removed at the first signs of eye redness or irritation - lens should be
removed in a clean environment only after workers have washed hands thoroughly. [CDC
NIOSH Current Intelligence Bulletin 59].
HANDS/FEET
Wear chemical protective gloves, eg. PVC.
Wear safety footwear or safety gumboots, eg. Rubber.
OTHER
路 Overalls.
路 PVC Apron.
路 PVC protective suit may be required if exposure severe.
路 Eyewash unit.
路 Ensure there is ready access to a safety shower.
GLOVE SELECTION INDEX
Glove selection is based on a modified presentation of the:
" Forsberg Clothing Performance Index" .
The effect(s) of the following substance(s) are taken into account in the
computer- generated selection: acetone
Protective Material CPI *.
__________________________________________
BUTYL/NEOPRENE A
PE/EVAL/PE A
PVDC/PE/PVDC A
BUTYL A
SARANEX- 23 2- PLY B
TEFLON B
SARANEX- 23 C
CPE C
HYPALON C
NITRILE+PVC C
PVA C
VITON/NEOPRENE C
NEOPRENE C
PVC C
NATURAL+NEOPRENE C
NATURAL RUBBER C
NITRILE C
__________________________________________
* CPI - Chemwatch Performance Index
A: Best Selection
B: Satisfactory; may degrade after 4 hours continuous immersion
C: Poor to Dangerous Choice for other than short term immersion
NOTE: As a series of factors will influence the actual performance of the glove,
a final selection must be based on detailed observation. -
* Where the glove is to be used on a short term, casual or infrequent basis,
factors such as "feel" or convenience (e.g. disposability), may dictate a choice
of gloves which might otherwise be unsuitable following long-term or frequent use.
A qualified practitioner should be consulted.
RESPIRATOR
Selection of the Class and Type of respirator will depend upon the level of breathing
zone contaminant and the chemical nature of the contaminant. Protection Factors (defined
as the ratio of contaminant outside and inside the mask) may also be important.
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Issue Date: 26-Mar-2007 Version No:1
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Section 8 - EXPOSURE CONTROLS / PERSONAL PROTECTION
Breathing Zone Level Maximum Protection Half- face Respirator Full- Face Respirator
ppm (volume) Factor
1000 10 AX- AUS -
1000 50 - AX- AUS
5000 50 Airline * -
5000 100 - AX- 2
10000 100 - AX- 3
100+ Airline**
* - Continuous Flow ** - Continuous-flow or positive pressure demand.
The local concentration of material, quantity and conditions of use determine the type of
personal protective equipment required.
For further information consult site specific
CHEMWATCH data (if available), or your
Occupational Health and Safety Advisor.
ENGINEERING CONTROLS
For flammable liquids and flammable gases, local exhaust ventilation or a process
enclosure ventilation system may be required. Ventilation equipment should be explosion
-resistant.
Air contaminants generated in the workplace possess varying "escape" velocities which, in
turn, determine the "capture velocities" of fresh circulating air required to effectively
remove the contaminant.
Type of Contaminant: Air Speed:
solvent, vapours, degreasing etc., evaporating 0.25- 0.5 m/s (50- 100 f/min.)
from tank (in still air).
aerosols, fumes from pouring operations, 0.5- 1 m/s (100- 200 f/min.)
intermittent container filling, low speed
conveyer transfers, welding, spray drift,
plating acid fumes, pickling (released at low
velocity into zone of active generation)
direct spray, spray painting in shallow booths, 1- 2.5 m/s (200- 500 f/min.)
drum filling, conveyer loading, crusher dusts,
gas discharge (active generation into zone of
rapid air motion)
Within each range the appropriate value depends on:
Lower end of the range Upper end of the range
1: Room air currents minimal or favourable to 1: Disturbing room air currents
capture
2: Contaminants of low toxicity or of nuisance 2: Contaminants of high toxicity
value only.
3: Intermittent, low production. 3: High production, heavy use
4: Large hood or large air mass in motion 4: Small hood- local control only
Simple theory shows that air velocity falls rapidly with distance away from the opening
of a simple extraction pipe. Velocity generally decreases with the square of distance
from the extraction point (in simple cases). Therefore the air speed at the extraction
point should be adjusted, accordingly, after reference to distance from the contaminating
source. The air velocity at the extraction fan, for example, should be a minimum of 1-2
m/s (200-400 f/min.) for extraction of solvents generated in a tank 2 meters distant from
the extraction point. Other mechanical considerations, producing performance deficits
within the extraction apparatus, make it essential that theoretical air velocities are
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Chemwatch Material Safety Data Sheet
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Issue Date: 26-Mar-2007 Version No:1
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Section 8 - EXPOSURE CONTROLS / PERSONAL PROTECTION
multiplied by factors of 10 or more when extraction systems are installed or used.
Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
APPEARANCE
Clear, colourless, highly volatile, highly flammable liquid with characteristic sweet
odour; mixes with water. Mixes in alcohol, ether, most hydrocarbons and oils.
PHYSICAL PROPERTIES
Liquid.
Mixes with water.
Molecular Weight: 58.08 Boiling Range (掳C): 56
Melting Range (掳C): - 95.4 Specific Gravity (water=1): 0.79 @ 20 C
Solubility in water (g/L): Miscible pH (as supplied): Not applicable
pH (1% solution): Not applicable Vapour Pressure (kPa): 24 @ 20 C
Volatile Component (%vol): 100 Evaporation Rate: 11 BuAc=1 VFast
Relative Vapour Density (air=1): 2.0 Flash Point (掳C): - 17
Lower Explosive Limit (%): 2.6 Upper Explosive Limit (%): 12.8
Autoignition Temp (掳C): 465 Decomposition Temp (掳C): Not Available
State: Liquid Viscosity: Not Available
log Kow (Prager 1995): - 0.24
log Kow (Sangster 1997): - 0.24
Section 10 - CHEMICAL STABILITY AND REACTIVITY INFORMATION
CONDITIONS CONTRIBUTING TO INSTABILITY
路 Product is considered stable under normal handling conditions.
路 Stable under normal storage conditions.
路 Hazardous polymerization will not occur.
Section 11 - TOXICOLOGICAL INFORMATION
POTENTIAL HEALTH EFFECTS
ACUTE HEALTH EFFECTS
SWALLOWED
Accidental ingestion of the material may be damaging to the health of the individual.
EYE
There is evidence that material may produce eye irritation in some persons and produce
eye damage 24 hours or more after instillation. Severe inflammation may be expected with
pain. There may be damage to the cornea. Unless treatment is prompt and adequate there
may be permanent loss of vision. Conjunctivitis can occur following repeated exposure.
The liquid may produce eye discomfort and is capable of causing temporary impairment of
vision and/or transient eye inflammation, ulceration.
SKIN
Skin contact with the material may damage the health of the individual; systemic effects
may result following absorption.
There is some evidence to suggest that the material may cause mild but significant
inflammation of the skin either following direct contact or after a delay of some time.
Repeated exposure can cause contact dermatitis which is characterised by redness,
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Section 11 - TOXICOLOGICAL INFORMATION
swelling and blistering.
Entry into the blood-stream, through, for example, cuts, abrasions or lesions, may
produce systemic injury with harmful effects. Examine the skin prior to the use of the
material and ensure that any external damage is suitably protected.
The material may cause skin irritation after prolonged or repeated exposure and may
produce on contact skin redness, swelling, the production of vesicles, scaling and
thickening of the skin.
INHALED
Inhalation of vapours or aerosols (mists, fumes), generated by the material during the
course of normal handling, may be damaging to the health of the individual.
There is some evidence to suggest that the material can cause respiratory irritation in
some persons. The body's response to such irritation can cause further lung damage.
Inhalation of vapours may cause drowsiness and dizziness. This may be accompanied by
sleepiness, reduced alertness, loss of reflexes, lack of co-ordination, and vertigo.
Ketone vapours irritate the nose, throat and mucous membrane. High concentrations depress
the central nervous system, causing headache, vertigo, poor concentration, sleep and
failure of the heart and breathing. Some ketones can cause multiple nerve disorders,
inducing "pins and needles" and weakness in the limbs.
Inhalation of acetone causes central nervous system depression, light-headedness,
incoherent speech, inco-ordination, stupor, low blood pressure, fast pulse, metabolic
acidosis, high blood sugar and ketosis. Rarely, convulsions and tubular necrosis may be
evident. Other symptoms of exposure may include restlessness, headache, vomiting, low
blood pressure and rapid and irregular pulse, eye and throat irritation, weakness of the
legs and dizziness. Inhalation of high concentrations may produce dryness of the mouth
and throat, nausea, inco-ordinated movement, loss of co-ordinated speech, drowsiness, and
in severe cases, coma. Inhalation of acetone vapours over long periods causes irritation
of the airways, coughing and headache. Rats exposed to a concentration of 5.22% for 1
hour showed clear signs of sleepiness; deaths occurred at 12.66%.
CHRONIC HEALTH EFFECTS
Substance accumulation, in the human body, may occur and may cause some concern following
repeated or long-term occupational exposure.
Workers exposed to acetone for long periods showed inflammation of the airways, stomach
and small bowel, attacks of giddiness and loss of strength. Exposure to acetone may
enhance the liver toxicity of chlorinated solvents.
TOXICITY AND IRRITATION
unless otherwise specified data extracted from RTECS - Register of Toxic Effects of Chemical Substances.
TOXICITY IRRITATION
Oral (man) TDLo: 2857 mg/kg Eye (human): 500 ppm - Irritant
Oral (rat) LD50: 5800 mg/kg Eye (rabbit): 3.95 mg - SEVERE
Inhalation (human) TCLo: 500 ppm Eye (rabbit): 20mg/24hr - Moderate
Inhalation (man) TCLo: 12000 ppm/4 hr Skin (rabbit):395mg (open) - Mild
Inhalation (man) TCLo: 10 mg/m鲁/6 hr Skin (rabbit): 500 mg/24hr - Mild
Inhalation (rat) LC50: 50100 mg/m鲁/8 hr
Dermal (rabbit) LD50: 20000 mg/kg
Section 12 - ECOLOGICAL INFORMATION
Fish LC50 (96hr.) (mg/l): 8300- 40000
Daphnia magna EC50 (48hr.) (mg/l): 10
log Kow (Prager 1995): - 0.24
log Kow (Sangster 1997): - 0.24
log Pow (Verschueren 1983): - 0.24
BOD5: 122%
ThOD: 72
Half- life Soil - High (hours): 168
Half- life Soil - Low (hours): 24
ACETONE
Chemwatch Material Safety Data Sheet
For Workplace - Small Volume Use Only. CHEMWATCH 1090
Issue Date: 26-Mar-2007 Version No:1
NC317TLP CD 2007/3 Page 14 of 16
Section 12 - ECOLOGICAL INFORMATION
Half- life Air - High (hours): 2790
Half- life Air - Low (hours): 279
Half- life Surface water - High (hours): 168
Half- life Surface water - Low (hours): 24
Half- life Ground water - High (hours): 336
Half- life Ground water - Low (hours): 48
Aqueous biodegradation - Aerobic - High (hours): 168
Aqueous biodegradation - Aerobic - Low (hours): 24
Aqueous biodegradation - Anaerobic - High (hours): 672
Aqueous biodegradation - Anaerobic - Low (hours): 96
Aqueous biodegradation - Removal secondary treatment - High (hours): 75%
Aqueous biodegradation - Removal secondary treatment - Low (hours): 54%
Aqueous photolysis half- life - High (hours): 270
Photooxidation half- life water - High (hours): 3.97E+06
Photooxidation half- life water - Low (hours): 9.92E+04
Photooxidation half- life air - High (hours): 2790
Photooxidation half- life air - Low (hours): 279
DO NOT discharge into sewer or waterways.
log Kow: -0.24
Half-life (hr) air: 312-1896
Half-life (hr) H2O surface water: 20
Henry's atm m鲁 /mol: 3.67E-05
BOD 5 if unstated: 0.31-1.76,46-55%
COD: 1.12-2.07
ThOD: 2.2
BCF: 0.69
Toxicity Fish: LC50(96) 5540-13000mg/L
Toxicity invertebrate: cell mult. inhib. 28-7500mg/L
Bioaccumulation: not sig
Nitrif. inhib.: 75% decr. at 840mg/L
Anaerobic effects: sig degrad
Degradation Biological: sig
processes Abiotic: Rxn OH*,photodissoc
In air, acetone is lost by photolysis and reaction with photochemically
produced hydroxyl radicals; the estimated half-life of these combined
processes is about 22 days. The relatively long half-life allows acetone
to be transported long distances from its emission source.
Acetone is highly soluble and slightly persistent in water, with a
half-life of about 20 hours; it is minimally toxic to aquatic life.
Acetone released to soil volatilises although some may leach into the
ground where it rapidly biodegrades.
Acetone does not concentrate in the food chain.
Drinking Water Standard: none available.
Soil Guidelines: none available.
Air Quality Standards: none available.
Section 13 - DISPOSAL CONSIDERATIONS
路 Recycle wherever possible.
路 Consult manufacturer for recycling options or consult local or regional waste
management authority for disposal if no suitable treatment or disposal facility can be
identified.
路 Dispose of by: Burial in a licenced land-fill or Incineration in a licenced apparatus
(after admixture with suitable combustible material).
路 Decontaminate empty containers. Observe all label safeguards until containers are
cleaned and destroyed.
ACETONE
Chemwatch Material Safety Data Sheet
For Workplace - Small Volume Use Only. CHEMWATCH 1090
Issue Date: 26-Mar-2007 Version No:1
NC317TLP CD 2007/3 Page 15 of 16
Section 14 - TRANSPORTATION INFORMATION
Labels Required: FLAMMABLE LIQUID
HAZCHEM: 2[Y]E
UNDG:
Dangerous Goods Class: 3 Subrisk: None
UN Number: 1090 Packing Group: II
Shipping Name:ACETONE
Air Transport IATA:
ICAO/IATA Class: 3 ICAO/IATA Subrisk: None
UN/ID Number: 1090 Packing Group: II
Special provisions: None
Shipping Name: ACETONE
Maritime Transport IMDG:
IMDG Class: 3 IMDG Subrisk: None
UN Number: 1090 Packing Group: II
EMS Number: F- E, S- D Special provisions: None
Shipping Name: ACETONE (ACETONE SOLUTIONS)
Section 15 - REGULATORY INFORMATION
POISONS SCHEDULE: S5, NZS4
REGULATIONS
acetone (CAS: 67-64-1) is found on the following regulatory lists;
Australia Exposure Standards
Australia High Volume Industrial Chemical List (HVICL)
Australia Illicit Drug Reagents/Essential Chemicals - Category III
Australia Inventory of Chemical Substances (AICS)
Australia National Pollutant Inventory
Australia Standard for the Uniform Scheduling of Drugs and Poisons (SUSDP) - Appendix E (Part 2)
Australia Standard for the Uniform Scheduling of Drugs and Poisons (SUSDP) - Appendix F (Part 3)
Australia Standard for the Uniform Scheduling of Drugs and Poisons (SUSDP) - Schedule 5
IMO MARPOL 73/78 (Annex II) - List of Other Liquid Substances
OECD Representative List of High Production Volume (HPV) Chemicals
United Nations Convention Against Illicit Traffic in Narcotic Drugs and Psychotropic Substances - Table II
United Nations List of Precursors and Chemicals Frequently used in the Illicit Manufacture of Narcotic Drugs and Psychotropic Substances Under International
Control - Table II
Section 16 - OTHER INFORMATION
Classification of the preparation and its individual components has drawn on official and
authoritative sources as well as independent review by the Chemwatch Classification
committee using available literature references.
This document is copyright. Apart from any fair dealing for the purposes of private study, research, review or
criticism, as permitted under the Copyright Act, no part may be reproduced by any process without written permission
from CHEMWATCH. TEL (+61 3) 9572 4700.
ACETONE
Chemwatch Material Safety Data Sheet
For Workplace - Small Volume Use Only. CHEMWATCH 1090
Issue Date: 26-Mar-2007 Version No:1
NC317TLP CD 2007/3 Page 16 of 16
Section 16 - OTHER INFORMATION
Issue Date: 26-Mar-2007
Print Date: 17-Dec-2007
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