TEREPHTHALIC ACID
Chemwatch Material Safety Data Sheet (REVIEW)
Issue Date: 17-Jun-2005 CHEMWATCH 32539
NC317TCP Version No:3
CD 2007/3 Page 1 of 9
Section 1 - CHEMICAL PRODUCT AND COMPANY IDENTIFICATION
PRODUCT NAME
TEREPHTHALIC ACID
SYNONYMS
C8-H6-O4, C6H4(COOH)2, "p-benzenedicarboxylic acid", "p-benzenedicarboxylic acid", "1, 4
-benzenedicarboxylic acid", "1, 4-benzenedicarboxylic acid", "p-phthalic acid", "p
-phthalic acid", "TA 12", TA-33MP, "PTA purified terephthalic acid", TPA
PRODUCT USE
In the manufacture of polyester film and sheet (following reaction with glycol); reagent
for alkali in wool; additve to poultry feeds; inhibits spontaneous mammary tumorigenesis
in mice.
SUPPLIER
Company: Quantum Chemicals Pty Ltd
Address:
70 Quantum Close
Dandenong South
Victoria 3175
Telephone: 03 8795 8000
Emergency Tel: 1300 131 001
Fax: 03 8795 8099
HAZARD RATINGS
Flammability
Toxicity
Body Contact
Reactivity
Chronic
SCALE: Min/Nil=0 Low=1 Moderate=2 High=3 Extreme=4
Section 2 - HAZARDS IDENTIFICATION
STATEMENT OF HAZARDOUS NATURE
NON-HAZARDOUS SUBSTANCE. NON-DANGEROUS GOODS. According to the Criteria of
NOHSC, and the ADG Code.
TEREPHTHALIC ACID
Chemwatch Material Safety Data Sheet (REVIEW)
Issue Date: 17-Jun-2005 CHEMWATCH 32539
NC317TCP Version No:3
CD 2007/3 Page 2 of 9
Section 2 - HAZARDS IDENTIFICATION
POISONS SCHEDULE
None
RISK SAFETY
Ingestion may produce health damage*. Avoid exposure - obtain special instructions
before use.
Cumulative effects may result following Take off immediately all contaminated clothing.
exposure*.
May produce discomfort of the eyes*. In case of contact with eyes rinse with plenty
of water and contact Doctor or Poisons
Information Centre.
May possibly affect fertility*.
* (limited evidence).
Section 3 - COMPOSITION / INFORMATION ON INGREDIENTS
NAME CAS RN %
terephthalic acid 100-21-0 >98
Section 4 - FIRST AID MEASURES
SWALLOWED
路 Immediately give a glass of water.
路 First aid is not generally required. If in doubt, contact a Poisons Information Centre
or a doctor.
EYE
If this product comes in contact with the eyes:
路 Immediately hold eyelids apart and flush the eye continuously with running water.
路 Ensure complete irrigation of the eye by keeping eyelids apart and away from eye and
moving the eyelids by occasionally lifting the upper and lower lids.
路 Continue flushing until advised to stop by the Poisons Information Centre or a doctor,
or for at least 15 minutes.
路 Transport to hospital or doctor without delay.
路 Removal of contact lenses after an eye injury should only be undertaken by skilled
personnel.
SKIN
If skin contact occurs:
路 Immediately remove all contaminated clothing, including footwear.
路 Flush skin and hair with running water (and soap if available).
路 Seek medical attention in event of irritation.
INHALED
路 If dust is inhaled, remove from contaminated area.
路 Encourage patient to blow nose to ensure clear passage of breathing.
路 If irritation or discomfort persists seek medical attention.
NOTES TO PHYSICIAN
Treat symptomatically.
Section 5 - FIRE FIGHTING MEASURES
EXTINGUISHING MEDIA
路 Foam.
TEREPHTHALIC ACID
Chemwatch Material Safety Data Sheet (REVIEW)
Issue Date: 17-Jun-2005 CHEMWATCH 32539
NC317TCP Version No:3
CD 2007/3 Page 3 of 9
Section 5 - FIRE FIGHTING MEASURES
路 Dry chemical powder.
路 BCF (where regulations permit).
路 Carbon dioxide.
路 Water spray or fog - Large fires only.
FIRE FIGHTING
路 Use water delivered as a fine spray to control fire and cool adjacent area.
路 Do not approach containers suspected to be hot.
路 Cool fire exposed containers with water spray from a protected location.
路 If safe to do so, remove containers from path of fire.
路 Equipment should be thoroughly decontaminated after use.
FIRE/EXPLOSION HAZARD
路 Solid which exhibits difficult combustion or is difficult to ignite.
路 Avoid generating dust, particularly clouds of dust in a confined or unventilated space
as dusts may form an explosive mixture with air, and any source of ignition, i.e.
flame or spark, will cause fire or explosion. Dust clouds generated by the fine
grinding of the solid are a particular hazard; accumulations of fine dust may burn
rapidly and fiercely if ignited.
路 Dry dust can also be charged electrostatically by turbulence, pneumatic transport,
pouring, in exhaust ducts and during transport.
路 Build-up of electrostatic charge may be prevented by bonding and grounding.
路 Powder handling equipment such as dust collectors, dryers and mills may require
additional protection measures such as explosion venting.
路 All movable parts coming in contact with this material should have a speed of less than
1-metre/sec.
FIRE INCOMPATIBILITY
Avoid contamination with oxidising agents i.e. nitrates, oxidising acids, chlorine
bleaches, pool chlorine etc. as ignition may result.
HAZCHEM: None
Section 6 - ACCIDENTAL RELEASE MEASURES
EMERGENCY PROCEDURES
MINOR SPILLS
路 Clean up all spills immediately.
路 Avoid contact with skin and eyes.
路 Wear impervious gloves and safety glasses.
路 Use dry clean up procedures and avoid generating dust.
路 Sweep up or
路 Vacuum up (consider explosion-proof machines designed to be grounded during storage and
use).
路 Place spilled material in clean, dry, sealable, labelled container.
MAJOR SPILLS
路 Clear area of personnel and move upwind.
路 Alert Fire Brigade and tell them location and nature of hazard.
路 Control personal contact by using protective equipment and dust respirator.
路 Prevent spillage from entering drains, sewers or water courses.
路 Avoid generating dust.
路 Sweep, shovel up. Recover product wherever possible.
路 Put residues in labelled plastic bags or other containers for disposal.
路 If contamination of drains or waterways occurs, advise emergency services.
TEREPHTHALIC ACID
Chemwatch Material Safety Data Sheet (REVIEW)
Issue Date: 17-Jun-2005 CHEMWATCH 32539
NC317TCP Version No:3
CD 2007/3 Page 4 of 9
Section 6 - ACCIDENTAL RELEASE MEASURES
EMERGENCY RESPONSE PLANNING GUIDELINES (ERPG)
The maximum airborne concentration below which it is believed that nearly all individuals could be exposed
for up to one hour WITHOUT experiencing or developing
life-threatening health effects is:
terephthalic acid 500 mg/m鲁
irreversible or other serious effects or symptoms which could impair an individual's ability to take
protective action is:
terephthalic acid 50 mg/m鲁
other than mild, transient adverse effects without perceiving a clearly defined odour is:
terephthalic acid 30 mg/m鲁
The threshold concentration below which most people will experience no appreciable risk of health effects:
terephthalic acid 10 mg/m鲁
American Industrial Hygiene Association (AIHA)
Ingredients considered according to the following cutoffs
Very Toxic (T+) >= 0.1% Toxic (T) >= 3.0%
R50 >= 0.25% Corrosive (C) >= 5.0%
R51 >= 2.5%
else >= 10%
where percentage is percentage of ingredient found in the mixture
Personal Protective Equipment advice is contained in Section 8 of the MSDS.
Section 7 - HANDLING AND STORAGE
PROCEDURE FOR HANDLING
路 Limit all unnecessary personal contact.
路 Wear protective clothing when risk of exposure occurs.
路 Use in a well-ventilated area.
路 When handling DO NOT eat, drink or smoke.
路 Always wash hands with soap and water after handling.
路 Avoid physical damage to containers.
路 Use good occupational work practice.
路 Observe manufacturer's storing and handling recommendations.
SUITABLE CONTAINER
Multi-ply paper bag with sealed plastic liner or heavy gauge plastic bag.
NOTE: Bags should be stacked, blocked, interlocked, and limited in height so that they
are stable and secure against sliding or collapse. Check that all containers are clearly
labelled and free from leaks. Packing as recommended by manufacturer.
STORAGE INCOMPATIBILITY
Avoid reaction with oxidising agents.
Avoid strong bases.
Reaction with nitric acid may be explosive.
STORAGE REQUIREMENTS
路 Store in original containers.
路 Keep containers securely sealed.
路 Store in a cool, dry, well-ventilated area.
路 Store away from incompatible materials and foodstuff containers.
路 Protect containers against physical damage and check regularly for leaks.
路 Observe manufacturer's storing and handling recommendations.
TEREPHTHALIC ACID
Chemwatch Material Safety Data Sheet (REVIEW)
Issue Date: 17-Jun-2005 CHEMWATCH 32539
NC317TCP Version No:3
CD 2007/3 Page 5 of 9
Section 7 - HANDLING AND STORAGE
_____________________________________________________
SAFE STORAGE WITH OTHER CLASSIFIED CHEMICALS
+ + + + + +
_____________________________________________________
+: May be stored together
O: May be stored together with specific preventions
X: Must not be stored together
Section 8 - EXPOSURE CONTROLS / PERSONAL PROTECTION
EXPOSURE CONTROLS
The following materials had no OELs on our records
鈥? terephthalic acid: CAS:100- 21- 0
MATERIAL DATA
Not available. Refer to individual constituents.
PERSONAL PROTECTION
EYE
路 Safety glasses.
路 Safety glasses with side shields.
路 Chemical goggles.
路 Contact lenses may pose a special hazard; soft contact lenses may absorb and
concentrate irritants. A written policy document, describing the wearing of lens or
restrictions on use, should be created for each workplace or task. This should include a
review of lens absorption and adsorption for the class of chemicals in use and an account
of injury experience. Medical and first-aid personnel should be trained in their removal
and suitable equipment should be readily available. In the event of chemical exposure,
begin eye irrigation immediately and remove contact lens as soon as practicable. Lens
should be removed at the first signs of eye redness or irritation - lens should be
removed in a clean environment only after workers have washed hands thoroughly. [CDC
NIOSH Current Intelligence Bulletin 59].
HANDS/FEET
Rubber gloves.
PVC gloves.
Safety footwear.
Rubber boots.
OTHER
Overalls.
PVC apron.
路 Barrier cream.
路 Eyewash unit.
TEREPHTHALIC ACID
Chemwatch Material Safety Data Sheet (REVIEW)
Issue Date: 17-Jun-2005 CHEMWATCH 32539
NC317TCP Version No:3
CD 2007/3 Page 6 of 9
Section 8 - EXPOSURE CONTROLS / PERSONAL PROTECTION
Ensure there is ready access to a safety shower.
RESPIRATOR
Protection Factor Half- Face Respirator Full- Face Respirator Powered Air Respirator
10 x ES P1 Air- line* -- PAPR- P1 -
50 x ES Air- line** P2 PAPR- P2
100 x ES - P3 -
Air- line* -
100+ x ES - Air- line** PAPR- P3
* - Negative pressure demand ** - Continuous flow.
The local concentration of material, quantity and conditions of use determine the type of
personal protective equipment required.
For further information consult site specific
CHEMWATCH data (if available), or your
Occupational Health and Safety Advisor.
ENGINEERING CONTROLS
General exhaust is adequate under normal operating conditions. If risk of overexposure
exists, wear SAA approved respirator. Correct fit is essential to obtain adequate
protection. Provide adequate ventilation in warehouse or closed storage areas. Air
contaminants generated in the workplace possess varying "escape" velocities which, in
turn, determine the "capture velocities" of fresh circulating air required to effectively
remove the contaminant.
Type of Contaminant: Air Speed:
solvent, vapours, degreasing etc., evaporating 0.25- 0.5 m/s (50- 100 f/min)
from tank (in still air)
aerosols, fumes from pouring operations, 0.5- 1 m/s (100- 200 f/min.)
intermittent container filling, low speed
conveyer transfers, welding, spray drift,
plating acid fumes, pickling (released at low
velocity into zone of active generation)
direct spray, spray painting in shallow booths, 1- 2.5 m/s (200- 500 f/min)
drum filling, conveyer loading, crusher dusts,
gas discharge (active generation into zone of
rapid air motion)
grinding, abrasive blasting, tumbling, high 2.5- 10 m/s (500- 2000 f/min.)
speed wheel generated dusts (released at high
initial velocity into zone of very high rapid
air motion).
Within each range the appropriate value depends on:
Lower end of the range Upper end of the range
1: Room air currents minimal or favourable to 1: Disturbing room air currents
capture
2: Contaminants of low toxicity or of nuisance 2: Contaminants of high toxicity
value only
3: Intermittent, low production. 3: High production, heavy use
4: Large hood or large air mass in motion 4: Small hood - local control only
Simple theory shows that air velocity falls rapidly with distance away from the opening
of a simple extraction pipe. Velocity generally decreases with the square of distance
from the extraction point (in simple cases). Therefore the air speed at the extraction
point should be adjusted, accordingly, after reference to distance from the contaminating
TEREPHTHALIC ACID
Chemwatch Material Safety Data Sheet (REVIEW)
Issue Date: 17-Jun-2005 CHEMWATCH 32539
NC317TCP Version No:3
CD 2007/3 Page 7 of 9
Section 8 - EXPOSURE CONTROLS / PERSONAL PROTECTION
source. The air velocity at the extraction fan, for example, should be a minimum of 1-2
m/s (200-400 f/min.) for extraction of solvents generated in a tank 2 meters distant from
the extraction point. Other mechanical considerations, producing performance deficits
within the extraction apparatus, make it essential that theoretical air velocities are
multiplied by factors of 10 or more when extraction systems are installed or used.
Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
APPEARANCE
Off- white crystalline powder; does not mix well with water. Soluble in alkalies, dimethyl
sulfoxide.
PHYSICAL PROPERTIES
Solid.
Does not mix with water.
Sinks in water.
Molecular Weight: 166.13 Boiling Range (掳C): Not applicable
Melting Range (掳C): sublimes 402 C Specific Gravity (water=1): 1.5
Solubility in water (g/L): Partly miscible pH (as supplied): Not applicable
pH (1% solution): 2.16 (saturated) Vapour Pressure (kPa): <0.0013 @ 20 C
Volatile Component (%vol): Negligible Evaporation Rate: Not applicable
Relative Vapour Density (air=1): Not applicable Flash Point (掳C): 260 (OC)
Lower Explosive Limit (%): 0.05 g/l Upper Explosive Limit (%): Not available
Autoignition Temp (掳C): 496.11 Decomposition Temp (掳C): Not available
State: Divided solid Viscosity: Not available
Section 10 - CHEMICAL STABILITY AND REACTIVITY INFORMATION
CONDITIONS CONTRIBUTING TO INSTABILITY
路 Presence of incompatible materials.
路 Product is considered stable.
路 Hazardous polymerisation will not occur.
Section 11 - TOXICOLOGICAL INFORMATION
POTENTIAL HEALTH EFFECTS
ACUTE HEALTH EFFECTS
SWALLOWED
The material is moderately discomforting to the gastro-intestinal tract and may be
harmful if swallowed in large quantity The toxicity of phthalates is not excessive due to
slow oral absorption and metabolism. Absorption is affected by fat in the diet. Repeated
doses can cause cumulative toxic effects, and symptoms include an enlarged liver which
often reverses if exposure is maintained. Carbohydrate metabolism is disrupted, and
cholesterol and triglyceride levels in the blood falls. There can also be withering of
the testicles. Some phthalates can increase the effects of antibiotics, thiamine (vitamin
B1) and sulfonamides.
EYE
The dust may produce eye discomfort causing smarting, pain and redness.
The material may be irritating to the eye, with prolonged contact causing inflammation.
Repeated or prolonged exposure to irritants may produce conjunctivitis.
TEREPHTHALIC ACID
Chemwatch Material Safety Data Sheet (REVIEW)
Issue Date: 17-Jun-2005 CHEMWATCH 32539
NC317TCP Version No:3
CD 2007/3 Page 8 of 9
Section 11 - TOXICOLOGICAL INFORMATION
SKIN
The material is moderately discomforting to the skin.
Open cuts, abraded or irritated skin should not be exposed to this material.
INHALED
The dust may be discomforting to the upper respiratory tract.
Persons with impaired respiratory function, airway diseases and conditions such as
emphysema or chronic bronchitis, may incur further disability if excessive concentrations
of particulate are inhaled.
CHRONIC HEALTH EFFECTS
Principal routes of exposure are by accidental skin and eye contact and inhalation of
generated dusts.
Exposure to phthalates over years leads to pain, numbness and spasms in the hands and
feet. Many people have developed multiple disorders in the nervous system and the
balancing system. Levels of sex hormones are reduced in women, leading to missed
ovulations and miscarriages. They also reduce sperm counts and fertility in men. They
mimic certain sex hormones and can damage the foetus. Phthalates are found in paints,
inks and glues.
TOXICITY AND IRRITATION
unless otherwise specified data extracted from RTECS - Register of Toxic Effects of Chemical Substances.
TOXICITY IRRITATION
Oral (rat) LD50: >6400 mg/kg Eye (rabbit): 500 mg/24h - Mild
Oral (mouse) LD50: 3200 mg/kg
Oral (mouse) LD50: >5000 mg/kg
Intraperitoneal (mouse) LD50: 1430 mg/kg
Section 12 - ECOLOGICAL INFORMATION
Half- life Soil - High (hours): 168
Half- life Soil - Low (hours): 24
Half- life Air - High (hours): 2326
Half- life Air - Low (hours): 232.6
Half- life Surface water - High (hours): 168
Half- life Surface water - Low (hours): 24
Half- life Ground water - High (hours): 336
Half- life Ground water - Low (hours): 48
Aqueous biodegradation - Aerobic - High (hours): 168
Aqueous biodegradation - Aerobic - Low (hours): 24
Aqueous biodegradation - Anaerobic - High (hours): 672
Aqueous biodegradation - Anaerobic - Low (hours): 96
Aqueous biodegradation - Removal secondary treatment - High (hours): 96%
Photolysis maximum light absorption - High (nano- m): 285.5
Photolysis maximum light absorption - Low (nano- m): 240.5
Photooxidation half- life air - High (hours): 2326
Photooxidation half- life air - Low (hours): 232.6
Koc: 292
Half-life (hr) air: 1392
BCF: 19
Toxicity Fish: LC50(96)1.1-1.9mg/L
Toxicity invertebrate: LC50(96)0.039mg/L
processes Abiotic: rapid hydrol. in water
TEREPHTHALIC ACID
Chemwatch Material Safety Data Sheet (REVIEW)
Issue Date: 17-Jun-2005 CHEMWATCH 32539
NC317TCP Version No:3
CD 2007/3 Page 9 of 9
Section 13 - DISPOSAL CONSIDERATIONS
路 Recycle wherever possible or consult manufacturer for recycling options.
路 Consult State Land Waste Authority for disposal.
路 Bury or incinerate residue at an approved site.
路 Recycle containers if possible, or dispose of in an authorised landfill.
Section 14 - TRANSPORTATION INFORMATION
HAZCHEM: None
NOT REGULATED FOR TRANSPORT OF DANGEROUS GOODS:UN, IATA,
IMDG
Section 15 - REGULATORY INFORMATION
POISONS SCHEDULE: None
REGULATIONS
terephthalic acid (CAS: 100-21-0) is found on the following regulatory lists;
Australia High Volume Industrial Chemical List (HVICL)
Australia Inventory of Chemical Substances (AICS)
OECD Representative List of High Production Volume (HPV) Chemicals
Section 16 - OTHER INFORMATION
Denmark Advisory list for selfclassification of dangerous substances
Substance CAS Suggested codes
terephthalic acid 100- 21- 0 R43
Classification of the preparation and its individual components has drawn on official and
authoritative sources as well as independent review by the Chemwatch Classification
committee using available literature references.
This document is copyright. Apart from any fair dealing for the purposes of private study, research, review or
criticism, as permitted under the Copyright Act, no part may be reproduced by any process without written permission
from CHEMWATCH. TEL (+61 3) 9572 4700.
Issue Date: 17-Jun-2005
Print Date: 4-Jan-2008
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