BASF Corporation
MATERIAL SAFETY DATA SHEET
Date prepared: March 23, 2004 page 1 of 6
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1. Product and Company Identification
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PRODUCT IDENTIFIER: Trimethylamineborane
SYNONYMS: Trimethylamineborane (TMAB)
PRODUCT USE: Aldehyde and ketone reduction reactions, electrochemical-type electroless plating
MANUFACTURED BY: BASF Corporation
1424 Mars-Evans City Road
Evans City, PA 16033
Customer Service: 1-866-4BORANES (24-Hour Telephone: 1-724-538-3510)
Transportation Emergency: 1-800-424-9300 in USA or 1-703-527-3887
BASF HOTLINE 24-Hour Emergency Response Information: 1-800-832-HELP
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2. Composition/Information on Ingredients
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wt% Synonym(s)
Trimethylamine borane (CASRN: 75-22-9) > 97 TMAB
Trimethylamine (CASRN: 75-50-3) <3 TMA
OSHA REGULATORY STATUS: Hazardous by definition of Hazard Communication Standard, 29 CFR
1910.1200.
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3. Hazards Identification
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Indications of danger (Annex II): Highly flammable (F) and Harmful (X)
Nature of special risk attributed to dangerous substances (Annex III): R11, R20, R36/37/38, R41
Safety advice concerning dangerous chemical substances (Annex IV): S7/9, S16, S36/37/39, S26, S29
EMERGENCY OVERVIEW: White to off-white crystalline, characteristic lingering, fishy odor of
trimethylamine. Contact with heat, ignition sources, or concentrated acids may cause flash fire due to
release of flammable hydrogen gas and trimethylamine vapors. Contact with anhydrous acid may cause
flash fire and may release poisonous and flammable diborane gas. Flammable solid. May cause
respiratory tract irritation, cough, dyspnea, and delayed pulmonary edema.
PHYSICAL HAZARDS: Contact with heat, ignition sources, or concentrated acids may cause flash fire
due to release of flammable hydrogen gas and trimethylamine vapors. Contact with anhydrous acid may
cause flash fire and may release poisonous and flammable diborane gas. Flammable solid.
POTENTIAL HEALTH EFFECTS: May cause respiratory tract irritation, cough, dyspnea, and delayed
pulmonary edema.
Primary Routes of Entry: Eye and skin contact, inhalation, ingestion
Target Organs: Eyes, skin, respiratory tract
Medical Conditions Generally Recognized as Aggravated by Exposure: Persons with preexisting
eye, skin, and respiratory conditions may be more susceptible to the effects of this
product.
Carcinogenicity: TMAB is not listed in the National Toxicology Program (NTP) Annual Report on
Carcinogens, not found to be a potential carcinogen in the International Agency for
Research on Cancer (IARC) Monographs, and not listed as an OSHA carcinogen.
Trimethylamineborane
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POTENTIAL ENVIRONMENTAL EFFECTS: No environmental toxicity data for the product. See Section
12 for additional information.
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4. First Aid Measures
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SEND TO A PHYSICIAN IN ALL CASES.
Eyes: Immediately flush eyes with plenty of water for at least 20 minutes while holding eyelids open.
Skin: Immediately flush skin with plenty of water for at least 20 minutes while removing contaminated
clothing and shoes. Dispose of contaminated clothing and shoes in compliance with all local, state, and
federal laws and regulations.
Ingestion: Give demulcent such as milk, olive oil, or margarine in small amounts up to 2 or 3 ounces.
Never give anything by mouth to an unconscious person.
Inhalation: Remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give
oxygen.
NOTES TO PHYSICIAN FOR OVEREXPOSURE TO TRIMETHYLAMINE - TMAB may decompose to
form trimethylamine (TMA). Therefore, any exposure to TMAB may also involve exposure to TMA.
Victims of overexposure by inhalation should be observed for up to 72 hours for delayed onset of
pulmonary edema. Use of acidics to neutralize swallowed contents is contraindicated.
Exposure to the vapor may cause minor transient edema of the corneal epithelium. This condition,
referred to as "glaucopsia", "blue haze" or "blue-gray haze", produces a blurring of vision against a
general bluish haze and the appearance of halos around bright objects. The effect disappears
spontaneously within a few hours after exposure ends, and leaves no sequelae. Although not detrimental
to the eye per se, glaucopsia predisposes an affected individual to physical accidents and reduces the
ability to undertake skilled tasks such as driving a motorized vehicle.
The hazards of trimethylamine are mainly due to its severe irritant and corrosive properties on the skin
and mucosal surfaces. Careful gastric lavage is required. There is no specific antidote, and treatment
should be directed at the control of symptoms and clinical condition.
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5. Fire Fighting Measures
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FLAMMABLE PROPERTIES: Flammable solid. TMAB decomposes to produce flammable
trimethylamine vapor, flammable hydrogen gas, and borates. This decomposition occurs faster with
higher temperatures. TMAB burns with a green flame and produces a dense white smoke.
Flashpoint (closed cup): 20掳F for trimethylamine
Flammable Limits: No information found for TMAB
For hydrogen, LFL: 4.0% UFL: 75%
For trimethylamine, LFL: 2.0% UFL: 11.6%
Autoignition Temperature: No information found for TMAB
EXTINGUISHING MEDIA: Use water spray, carbon dioxide, or dry chemical extinguisher. Use water
spray to keep fire-exposed containers cool. DO NOT use halogenated fire extinguishing agents.
UNUSUAL FIRE AND EXPLOSION HAZARDS: Under fire conditions TMAB can generate flammable
hydrogen and trimethylamine gases. Proper care must be taken in handling and opening any fire-
exposed TMAB containers. Contact with concentrated acids, excessive heat, or ignition sources may
cause flash fire due to liberation of flammable hydrogen gas and trimethylamine vapor. Reaction with
anhydrous acids liberates toxic and flammable diborane gas and flammable hydrogen gas. If TMAB
solutions are filtered using charcoal, do not allow charcoal and paper to dry; they may self-ignite. Keep
wet while in use. Before discarding, in well-ventilated area free of flammable materials and ignition
sources, pour dilute (5-10%) hydrochloric acid through used filter paper, then add used charcoal to acid.
Flammable hydrogen gas will evolve. Containers can buildup pressure if exposed to heat.
PROTECTION OF FIRE FIGHTERS: Wear full protective clothing, including protective gloves and boots.
For respiratory protection, wear a NIOSH-approved self-contained breathing apparatus with full
facepiece operated in a positive-pressure mode. Protect against possible corrosive smoke, fumes, and
waters. Work upwind if possible.
Trimethylamineborane
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6. Accidental Release Measures
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PROCEDURES FOR CLEANUP: Wear recommended personal protective equipment. Be prepared to
fight fire. Eliminate ignition sources. Sweep up and place in a dry metal container, properly label, and
cover. Properly dispose of all residues immediately. Take immediately to a waste handling area. Handle
in compliance with all local, state, and federal laws and regulations.
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7. Handling And Storage
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HYGIENIC PRACTICES: Use only with adequate ventilation. Keep container tightly closed. Wash
thoroughly after handling. Do not get in eyes, on skin, or clothing. Do not breathe vapor or dust.
STORAGE: Store in a cool, dry place. Under certain conditions this product can generate flammable
hydrogen and trimethylamine gases. Proper care must be taken in storage and when opening this
container. Do not expose to heat and protect from direct sunlight.
WORK PRACTICES: Keep away from sparks, flame, and other ignition sources (e.g., pilot lights, electric
motors, and static electricity), acids, oxidizers, and halogenated hydrocarbons. Maintain a nitrogen
blanket on vessels containing TMAB or TMAB solutions. Use non-sparking tools when opening or closing
containers. Bond and ground all systems when handling. Since empty containers retain product residue,
follow label warnings even after container is emptied.
PROTECTIVE MEASURES DURING REPAIR AND MAINTENANCE OF CONTAMINATED
EQUIPMENT: See Section 8.
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8. Exposure Controls/Personal Protection
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ENGINEERING CONTROLS: Provide adequate local exhaust ventilation to maintain worker exposure
below exposure limits. Prevent electrostatic charge buildup by using common bonding and grounding
techniques. Maintain a nitrogen blanket on vessels containing TMAB or TMAB solutions.
EXPOSURE CONTROLS: None established for the trimethylamine borane.
For trimethylamine: ACGIH TLV-TWA: 5 ppm
ACGIH TLV-STEL: 15 ppm
ACGIH has not established a Biological Exposure Index (TLV-BEI) for
trimethylamine.
The IDLH for trimethylamine is not determined.
Odor threshold of 2.1x10-4 ppm has been reported. Seven percent of
humans are unable to smell trimethylamine.
PERSONAL PROTECTIVE EQUIPMENT:
Normal Use & Handling: When exposure to eyes and skin is possible, wear chemical protective goggles
and flame-retardant protective clothing. Glove permeation data does not exist for this product. Exposure
limits have not been established for trimethylamine borane. When inhalation of vapor or dust is possible,
wear a NIOSH-approved self-contained breathing apparatus with full facepiece operated in a positive-
pressure mode. Eye wash and safety showers must be available and in good working order.
Emergency Handling: For firefighting, wear full protective clothing, including protective gloves and boots.
For chemical spills, wear special protective clothing (vapor-protective suit with additional chemical flash
fire escape protection, as specified in NFPA 1991). For respiratory protection, wear a NIOSH-approved
self-contained breathing apparatus with full facepiece operated in a positive-pressure mode.
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9. Physical And Chemical Properties
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APPEARANCE: White to off-white crystalline
ODOR: Characteristic, lingering, fishy odor of trimethylamine
MELTING POINT: 94掳C (201掳F)
BOILING POINT: 171掳C (340掳F)
SOLUBILITY IN WATER: 1.3 weight percent at 20掳C (68掳F)
Trimethylamineborane
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VAPOR PRESSURE: 0.8 mm @ 23掳C, 77.2 mm @ 97掳C
DENSITY: 0.81 g/ml @ 20掳C
THERMAL STABILITY: More stable than primary or secondary amine boranes. A sample maintained at
75掳C for 48 hours lost some weight but did not show any violent or rapid decomposition. Very slow
decomposition does occur at ~70掳C.
MOLECULAR WEIGHT: 72.96
FORMULA: (CH3)3NBH3
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10. Stability And Reactivity
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STABILITY (CONDITIONS TO AVOID): Stable. Keep away from heat, sparks, flame, and other ignition
sources (e.g., pilot lights, electric motors, and static electricity). See THERMAL STABILITY, Section 9,
PHYSICAL AND CHEMICAL PROPERTIES.
INCOMPATIBILITY (SPECIFIC MATERIALS TO AVOID): Moist air, acids, acid chlorides, acid
anhydrides, oxidizing agents, alcohols, halogenated hydrocarbons, heavy metals, heavy metal salts,
oxygen.
HAZARDOUS DECOMPOSITION PRODUCTS: Hydrogen, trimethylamine, carbon monoxide, carbon
dioxide, nitrogen oxides, boric acid, borates Heavy metals catalyze decomposition and breakdown
releases flammable hydrogen gas.
HAZARDOUS POLYMERIZATION: Not expected to occur.
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11. Toxicological Information
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Trimethylamine borane (TMAB) is not highly toxic or toxic by the oral or dermal routes and is not
irritating to the eyes and skin based on animal testing. TMAB animal studies done in the 1950's may
have given misleading results. The older studies were done using research and development samples of
TMAB and are thought to have contained an impurity which caused the misleading results.
No information is available on inhalation or sensitization testing of TMAB. Based on related
reactions for other amine boranes, the inhalation effects for TMAB would be expected to be similar to
trimethylamine which can cause respiratory tract irritation, cough, dyspnea, and delayed pulmonary
edema.
Trimethylamine is an in vitro mutagen.
TOXICOLOGY DATA:
For trimethylamine borane, LD50(oral-rat): >5 g/kg
LD50(dermal-rabbit): >2 g/kg
For trimethylamine, LD50(oral-rat): 500 mg/kg
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12. Ecological Information
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ECOLOGICAL DATA: No information found for trimethylamine borane.
For triethylamine,
FISH TOXICITY (Oryzias latipes): LC50: 1000000 ug/L 48 hours
ALGAL TOXICITY (Gloeotaenium loitlesbergerianu): 5900 ug/L 96 hours)
FATE & TRANSPORT: Kow: 0.16 (log = -0.796)
Koc: 8.79 (log = 0.944) (estimated from Kow)
BIOCONCENTRATION: 0.15 (estimated from Kow)
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13. Disposal Considerations
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WASTE DISPOSAL: Do not flush to sewer. Dispose in compliance with all local, state, and federal laws
and regulations.
Trimethylamineborane
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14. Transport Information
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HAZARDOUS MATERIALS/DANGEROUS GOODS CLASSIFICATION:
Proper Shipping Name: Flammable solid, organic, n.o.s. (trimethylamine borane)
Hazard Class: 4.1
Packaging Group: II
Identification Number: UN1325
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15. Regulatory Information
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TSCA: Trimethylamine borane and trimethylamine are listed on the TSCA Public Inventory.
SARA 313 INFORMATION: This product contains no chemicals subject to the reporting requirements of
Section 313 of Title III of the Superfund Amendments and Reauthorization Act of 1986 and 40 CFR 372.
CERCLA/SUPERFUND: The reportable quantity (RQ) for trimethylamine (TMA) is 100 pounds.
EINECS: 200-850-4 for trimethylamine borane, 200-875-0 for trimethylamine
EUROPEAN LABEL INFORMATION:
Symbols: F, Xn
Indications of danger (Annex II): Highly flammable (F) and Harmful (Xn)
Nature of special risk attributed to dangerous substances (Annex III):
R11 Highly flammable.
R20 Harmful by inhalation.
R36/37/38 Irritating to eyes, respiratory system, and skin.
R41 Risk of serious damage to eyes.
Safety advice concerning dangerous chemical substances (Annex IV):
S7/9 Keep container tightly closed and in a well-ventilated place.
S16 Keep away from sources of ignition - no smoking.
S36/37/39 Wear suitable protective clothing, gloves, eye/face protection.
S26 In case of contact with eyes, rinse immediately with plenty of water and seek
medical advice.
S29 Do not empty into drains.
CALIFORNIA: This product does not contain a chemical known to the State of California to cause
cancer.
NEW JERSEY: This product contains trimethylamine, a chemical listed on the New Jersey Department
of Health Hazard Right-to-Know Program Hazardous Substance List as a special health hazard.
PENNSYLVANIA: This product contains trimethylamine (methanamine, N,N-dimethyl) which is subject to
the Pennsylvania Worker and Community Right-to-Know Act.
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16. Other Information
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MSDS STATUS: Revised Sections 1 and 16.
IMPORTANT: WHILE THE DESCRIPTIONS, DESIGNS, DATA AND INFORMATION CONTAINED HEREIN ARE PRESENTED
IN GOOD FAITH AND BELIEVED TO BE ACCURATE, IT IS PROVIDED FOR YOUR GUIDANCE ONLY. BECAUSE MANY
FACTORS MAY AFFECT PROCESSING OR APPLICATION/USE, WE RECOMMEND THAT YOU MAKE TESTS TO
DETERMINE THE SUITABILITY OF A PRODUCT FOR YOUR PARTICULAR PURPOSE PRIOR TO USE. NO WARRANTIES
OR ANY KIND, EITHER EXPRESSED OR IMPLIED, INCLUDING WARRANTIES OF MERCHANTABILITY OR FITNESS FOR
A PARTICULAR PURPOSE, ARE MADE REGARDING PRODUCTS DESCRIBED OR DESIGNS, DATA OR INFORMATION
SET FORTH, OR THAT THE PRODUCTS, DESIGNS, DATA OR INFORMATION MAY BE USED WITHOUT INFRINGING THE
INTELLECTUAL PROPERTY RIGHTS OF OTHERS. IN NO CASE SHALL THE DESCRIPTIONS, INFORMATION, DATA OR
DESIGNS PROVIDED BE CONSIDERED A PART OF OUR TERMS AND CONDITION OF SALE. FURTHER, YOU
EXPRESSLY UNDERSTAND AND AGREE THAT THE DESCRIPTIONS, DESIGNS, DATA, AND INFORMATION FURNISHED
Trimethylamineborane
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BY BASF HEREUNDER ARE GIVEN GRATIS AND BASF ASSUMES NO OBLIGATION OR LIABILITY FOR THE
DESCRIPTION, DESIGNS, DATA AND INFORMATION GIVEN OR RESULTS OBTAINED, ALL SUCH BEING GIVEN AND
ACCEPTED AT YOUR RISK.
漏 2004
file: TMAB-MSDS-ANSI-98-R3-BASF
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