SIGMA-ALDRICH
MATERIAL SAFETY DATA SHEET
Date Printed: 03/03/2004
Date Updated: 02/14/2003
Version 1.3
Section 1 - Product and Company Information
Product Name METHYL ORANGE, A.C.S. REAGENT
Product Number 114510
Brand ALDRICH
Company Sigma-Aldrich
Street Address 3050 Spruce Street
City, State, Zip, Country SAINT LOUIS MO 63103 US
Technical Phone: 314 771 5765
Emergency Phone: 414 273 3850 Ext. 5996
Fax: 800 325 5052
Section 2 - Composition/Information on Ingredient
Substance Name CAS # SARA 313
METHYL ORANGE 547-58-0 No
Formula C14H14N3NaO3S
Synonyms C.I. 13025 * C.I. Acid Orange 52 * Diazoben *
4-Dimethylaminoazobenzene-4'-sulphonic acid
sodium salt *
p-((p-(Dimethylamino)phenyl)azo)benzenesulfonic
acid sodium salt * Eniamethyl Orange * Gold
Orange * Helianthine * Helianthine B * Kca Methyl
Orange * Methyl Orange * Methyl Orange B *
Methyloranz (Czech) * Orange 3 * Orange III *
Oranz III (Czech) * Oranz kysela 52 (Czech) *
Oranz methylova (Czech) * Tropaeolin
RTECS Number: DB6327000
Section 3 - Hazards Identification
EMERGENCY OVERVIEW
Toxic.
Toxic if swallowed.
HMIS RATING
HEALTH: 2
FLAMMABILITY: 0
REACTIVITY: 0
NFPA RATING
HEALTH: 2
FLAMMABILITY: 0
REACTIVITY: 0
For additional information on toxicity, please refer to Section 11.
Section 4 - First Aid Measures
ORAL EXPOSURE
If swallowed, wash out mouth with water provided person is
conscious. Call a physician immediately.
INHALATION EXPOSURE
If inhaled, remove to fresh air. If not breathing give
artificial respiration. If breathing is difficult, give oxygen.
DERMAL EXPOSURE
In case of skin contact, flush with copious amounts of water for
at least 15 minutes. Remove contaminated clothing and shoes.
Call a physician.
EYE EXPOSURE
In case of contact with eyes, flush with copious amounts of
water for at least 15 minutes. Assure adequate flushing by
separating the eyelids with fingers. Call a physician.
Section 5 - Fire Fighting Measures
FLASH POINT
N/A
AUTOIGNITION TEMP
N/A
FLAMMABILITY
N/A
EXTINGUISHING MEDIA
Suitable: Water spray. Carbon dioxide, dry chemical powder, or
appropriate foam.
FIREFIGHTING
Protective Equipment: Wear self-contained breathing apparatus
and protective clothing to prevent contact with skin and eyes.
Specific Hazard(s): Emits toxic fumes under fire conditions.
Section 6 - Accidental Release Measures
PROCEDURE TO BE FOLLOWED IN CASE OF LEAK OR SPILL
Evacuate area.
PROCEDURE(S) OF PERSONAL PRECAUTION(S)
Wear self-contained breathing apparatus, rubber boots, and heavy
rubber gloves.
METHODS FOR CLEANING UP
Sweep up, place in a bag and hold for waste disposal. Avoid
raising dust. Ventilate area and wash spill site after material
pickup is complete.
Section 7 - Handling and Storage
HANDLING
User Exposure: Do not breathe dust. Do not get in eyes, on skin,
on clothing. Avoid prolonged or repeated exposure.
STORAGE
Suitable: Keep tightly closed.
Section 8 - Exposure Controls / PPE
ENGINEERING CONTROLS
ALDRICH - 114510 www.sigma-aldrich.com Page 2
Use only in a chemical fume hood. Safety shower and eye bath.
PERSONAL PROTECTIVE EQUIPMENT
Respiratory: Government approved respirator.
Hand: Compatible chemical-resistant gloves.
Eye: Chemical safety goggles.
GENERAL HYGIENE MEASURES
Wash contaminated clothing before reuse. Wash thoroughly after
handling.
Section 9 - Physical/Chemical Properties
Appearance Color: Orange
Form: Powder Crystals
Property Value At Temperature or Pressure
Molecular Weight 327.34 AMU
pH N/A
BP/BP Range N/A
MP/MP Range N/A
Freezing Point N/A
Vapor Pressure N/A
Vapor Density N/A
Saturated Vapor Conc. N/A
Bulk Density N/A
Odor Threshold N/A
Volatile% N/A
VOC Content N/A
Water Content N/A
Solvent Content N/A
Evaporation Rate N/A
Viscosity N/A
Surface Tension N/A
Partition Coefficient N/A
Decomposition Temp. N/A
Flash Point N/A
Explosion Limits N/A
Flammability N/A
Autoignition Temp N/A
Refractive Index N/A
Optical Rotation N/A
Miscellaneous Data N/A
Solubility N/A
N/A = not available
Section 10 - Stability and Reactivity
STABILITY
Stable: Stable.
Materials to Avoid: Strong oxidizing agents.
HAZARDOUS DECOMPOSITION PRODUCTS
Hazardous Decomposition Products: Carbon monoxide, Carbon dioxide,
Nitrogen oxides, Sulfur oxides.
HAZARDOUS POLYMERIZATION
Hazardous Polymerization: Will not occur
Section 11 - Toxicological Information
ALDRICH - 114510 www.sigma-aldrich.com Page 3
ROUTE OF EXPOSURE
Skin Contact: May cause skin irritation.
Skin Absorption: May be harmful if absorbed through the skin.
Eye Contact: May cause eye irritation.
Inhalation: Material may be irritating to mucous membranes and
upper respiratory tract. May be harmful if inhaled.
Ingestion: Toxic if swallowed.
SIGNS AND SYMPTOMS OF EXPOSURE
To the best of our knowledge, the chemical, physical, and
toxicological properties have not been thoroughly investigated.
TOXICITY DATA
Oral
Rat
60 mg/kg
LD50
Intraperitoneal
Mouse
101 MG/KG
LD50
CHRONIC EXPOSURE - MUTAGEN
Species: Human
Dose: 4 MG/L
Cell Type: fibroblast
Mutation test: Unscheduled DNA synthesis
Species: Mouse
Dose: 150 UMOL/L
Cell Type: Embryo
Mutation test: Morphological transformation.
Species: Hamster
Dose: 2500 UG/L
Cell Type: kidney
Mutation test: Morphological transformation.
Mutation test: Histidine reversion (Ames)
Section 12 - Ecological Information
No data available.
Section 13 - Disposal Considerations
APPROPRIATE METHOD OF DISPOSAL OF SUBSTANCE OR PREPARATION
Contact a licensed professional waste disposal service to dispose
of this material. Dissolve or mix the material with a combustible
solvent and burn in a chemical incinerator equipped with an
afterburner and scrubber. Observe all federal, state, and local
environmental regulations.
Section 14 - Transport Information
DOT
Proper Shipping Name: Toxic solids, organic, n.o.s.
UN#: 2811
ALDRICH - 114510 www.sigma-aldrich.com Page 4
Class: 6.1
Packing Group: Packing Group III
Hazard Label: Toxic substances.
PIH: Not PIH
IATA
Proper Shipping Name: Toxic solid, organic, n.o.s.
IATA UN Number: 2811
Hazard Class: 6.1
Packing Group: III
Section 15 - Regulatory Information
EU ADDITIONAL CLASSIFICATION
Symbol of Danger: T
Indication of Danger: Toxic.
R: 25
Risk Statements: Toxic if swallowed.
S: 45
Safety Statements: In case of accident or if you feel unwell,
seek medical advice immediately (show the label where possible).
US CLASSIFICATION AND LABEL TEXT
Indication of Danger: Toxic.
Risk Statements: Toxic if swallowed.
Safety Statements: In case of accident or if you feel unwell,
seek medical advice immediately (show the label where possible).
UNITED STATES REGULATORY INFORMATION
SARA LISTED: No
TSCA INVENTORY ITEM: Yes
CANADA REGULATORY INFORMATION
WHMIS Classification: This product has been classified in
accordance with the hazard criteria of the CPR, and the MSDS
contains all the information required by the CPR.
DSL: Yes
NDSL: No
Section 16 - Other Information
DISCLAIMER
For R&D use only. Not for drug, household or other uses.
WARRANTY
The above information is believed to be correct but does not
purport to be all inclusive and shall be used only as a guide. The
information in this document is based on the present state of our
knowledge and is applicable to the product with regard to
appropriate safety precautions. It does not represent any
guarantee of the properties of the product. Sigma-Aldrich Inc.,
shall not be held liable for any damage resulting from handling or
from contact with the above product. See reverse side of invoice
or packing slip for additional terms and conditions of sale.
Copyright 2004 Sigma-Aldrich Co. License granted to make unlimited
paper copies for internal use only.
ALDRICH - 114510 www.sigma-aldrich.com Page 5
|