PUROMYCIN Safety Data Sheet
Revised: 09.02.04
Replaces: 10.01.04 Date of printing: 09.02.04 Page 1 of 2
1. Name of substance/preparation and company
1.1 Commercial product: Puromycin
Cat.-No.: ant-pr-1, ant-pr-5 (10mg/ml solution)
1.2 Company: CAYLA SAS- InvivoGen
5 rue Jean Rodier BP 4437
31 405 Toulouse Cedex 04 France
Tel. ++33 (0)5 62 71 69 39
Information obtainable from: ++33 (0)5 62 71 69 39
This product is for laboratory use only and is not intended for human or animal diagnostics, therapeutic or clinical uses
2. Composition/Information on constituents
The following list shows components of this product classified as hazardous based on physical properties and health effects
Puromycin, not classified as hazardous component
CAS-No.: 58-58-2
Molecular formula: C22H29N7O52HCL
Molecular weight: 544.4
EC number not available
3. Hazards identification
Warnings: The usual precautions taken when handling chemicals should be observed.
Puromycin is a potential hazardous compound
CAUTION: may be harmful if swallowed
- Eyes: May cause irritation.
-Skin: Can cause moderate skin irritation,. Not likely to cause permanent damage.
- Inhalation: Can cause moderate respiratory irritation.
-Ingestion: may be harmful if swallowed
Chronic effects:
- target organs: pancreas, liver, kidney
Target organ Data:
- target organs: pancreas, liver, kidney
See RTCES n掳 AU7355000 for complete information
4. First aid measures
First aid:
Eye contact: Wash immediately eyes with plenty of water for at least 15 minutes. Get medical attention;
Skin contact: Wash off with plenty of water and soap, remove contaminated clothes. Get medical attention
Ingestion: give plenty of water if conscious. If vomiting occurs naturally, wash mouth out. Do not induce vomiting unless directed to do so by
medical personnel. Obtain medical attention if symptoms develop.
Inhalation: Remove victim to fresh air, if malaise develops go to a physician, if breathing is difficult give oxygen.
Instructions for symptomatic treatment by a physician: Treat symptomatically
5. Fire-fighting measures
Flash point Degree : Not available
Upper flammable limit %: Not available
Lower flammable limit %: Not available
Autoignition temperature degree: Not available
Extinguishing media: Use alcohol or resistant foam, carbon dioxide or dry chemical fighting fire.
Hazardous combustion products: toxic fumes of carbon dioxide, carbon monoxide, nitrogen oxidesdense smoke
6. Accidental release measures
Refer to section 8 for personal protection equipment recommendations.
After spillage: Sweep up spilled substance carefully.
Absorbent material: suitable absorbent material like .
Damage limitation: Special measures to limit damage are to be taken.
7. Handling and storage
Storage of some material could be regulated by federal, state, and/or local laws.
7.1 Handling: toxic material. Avoid contacting and breathing the material.
Use only in a ventilated area. Keep away form sources of ignition; wear protective clothes
7.2 Storage: Store in a cool place at ambient pressure, and in suitable storage area.
Hydrophilic material; Keep tightly closed when not in use
PUROMYCIN Safety Data Sheet <~
Revised: 09.02.04
Replaces: 10.01.04 Date of printing: 09.02-04 Page 2 of 2
8. Exposure controls- personal protection
Engineering controls : local exhaust ventilation or other engineering controls are normally required when handling or using this product to avoid
overexposure.
Respiratory protection: wear protective respiratory mask
Eye protection: use protective glasses
Hand protection: wear protective compatible resistant gloves
Hygiene: Wash hands before breaks and at the end of the work.
9. Physical and chemical properties
Physical state : solution
Colour: colorless
Odour: none
PH: N.A.
Boiling point: no data
Melting point: 172掳C (puromycin powder)
Solubility in water: soluble
Density :
Viscosity: not determined
10. Stability and reactivity
Stability : stable under normal conditions
Conditions to avoid : heat, strong oxidising agents
Reactions: Not known when used appropriately.
Hazardous decomposition products : Carbon monoxide, Carbon dioxide. Nitrogen oxides
Hazardous polymerisation: will not occur
11. Toxicological information
LD50 oral/ingestion not known
LD50 dermal not known
LD50 inhalation/respiratory not known
Toxicologic information: Intoxication has so far not become known.
See actual entry in RTECS for complete toxicological informations.
12. Ecological information
Ecotoxicity: not available
Environmental fate: Bioconcentration is not expected to occur
13. Disposal considerations
Regulatory information: not applicable
Waste disposal route: Can be sent to an incineration plant in accordance with all state, federal, local regulations.
Clean up and dispose of waste in accordance with all state, federal, local regulations.
14. Transport information
UN number Not available
ADR/RID/IATA: Not controlled under ADR/IATA
Proper Shipping Name: Puromycin
Notes: product non subject to current regulations for transportation of hazardous goods (GGVS/ADR,
GGVE/RID, IMDG, IATA/ICAO).
Hazard class No hazardous component
15. Regulatory Information
Notes:
R phrases This product is not classified as hazardous compoundaccording to EU regulations
S24/26 Avoid contact with skin and eyes
S36/37/38 Wear protective clothing, respiratory mask, gloves and eyes protection
16. Other information
The information herein is believed to be correct as of the date hereof, but is provided without warranty
of any kind. The recipient of our product is responsible for ensuring that, where applicable, existing
laws and guidelines are observed.
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