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MSDS Material Safety Data Sheet
CAS

86-21-5
3770-50-1

File Name: pipharm_com---msds-10020.asp
 
                                                                      SHANGHAI PI CHEMICALS LTD.





                             Material Safety Data Sheet





           Section 1 鈥? Chemical Product and Company Identification





MSDS Name:                     Indole-2-carboxylic acid ethyl ester

Synonyms:

Company Identification:        Shanghai PI Chemicals Ltd.

                               Room 6-306, Building 2

                               1341 Pudong South Road

                               Pudong New Area, Shanghai 200212, China

Telephone Number:              86-21-51389368

Fax Number:                    86-21-51389367

Emergency Number:              86-21-51389369







           Section 2 鈥? Product Information





Catalog Number:                PI-10020

CAS #:                         3770-50-1

MDL #:                         MFCD00005609

Purity:                        98.0%

EINECS#                        223-206-4







           Section 3 鈥? Physical and Chemical Properties





Physical state:                Crystalline powder

Color:                         White to yellow

Odor:                          Not available

Molecular Formula:             C11H11NO2

Molecular Weight:              189.21

Freezing/Melting Point:        121-124 deg C

Boiling Point:                 Not available

Flash Point:                   Not available

Autoignition Temperature:      Not available

Refractive Index (nD20):       Not available

Density:                       Not available

Decomposition Temperature:     Not available

Solubility:                    Insoluble in water







           Section 4 鈥? Hazards Identification





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                                                                                 SHANGHAI PI CHEMICALS LTD.





Eye:          Causes eye irritation.

Skin:         Causes skin irritation. Harmful if absorbed through the skin.

Ingestion:    May cause irritation of the digestive tract. Toxic if swallowed.

Inhalation: May be harmful if inhaled. Causes respiratory tract irritation.









            Section 5 鈥? First Aid Measures





Eye:          Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower

              eyelids. Get medical aid.

Skin:         Get medical aid. Flush skin with plenty of water and soap for at least 15 minutes while

              removing contaminated clothing and shoes. Get medical aid if irritation develops and persists.

Ingestion:    Get medical aid immediately. Wash mouth out with water.

Inhalation: Remove from exposure and move to fresh air immediately. If not breathing, give artificial

              respiration. If breathing is difficult, give oxygen. Get medical aid.







            Section 6 鈥? Stability and Reactivity





Chemical Stability:                        Stable under normal temperatures and pressures.

Materials to avoid:                        Strong oxidizing agents.

Conditions to Avoid:                       Incompatible materials.

Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, nitrogen oxides.

Hazardous Polymerization:                  Will not occur.







            Section 7 鈥? Handling and Storage





Handling:     Avoid breathing dust, vapor, mist, or gas. Keep container tightly closed. Avoid contact with

              skin and eyes. Wash thoroughly after handling. Mechanical exhaust required.

Storage:      Store in a cool, dry place. Store in a tightly closed container. Store at 0-6 deg C.







           Section 8 鈥? Personal Protection





Eyes:         Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's

              eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.

Skin:         Wear appropriate protective gloves to prevent skin exposure.

Clothing:     Wear appropriate protective clothing to prevent skin exposure.

Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN

              149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits

              are exceeded or if irritation or other symptoms are experienced.









                                                      2

                                                                             SHANGHAI PI CHEMICALS LTD.





         Section 9 鈥? Fire and Explosion Hazard Data





General Information: As in any fire, wear a self-contained breathing apparatus, MSHA/NIOSH (approved

                         or equivalent) and protective clothing to prevent contact with skin and eyes.

Extinguishing Media: Use water spray, dry chemical, carbon dioxide, or appropriate foam.







         Section 10 鈥? Accidental Release Measures





General Information: Use proper personal protective equipment as indicated in Section 8.

Spills/Leaks:             Vacuum or sweep up material and place into a suitable disposal container.







         Section 11 鈥? Toxicological Information





RTECS#:             CAS#3770-50-1: Not available

LD50/LC50:          RTECS: Not available.

Carcinogenicity: Indole-2-carboxylic acid ethyl ester - Not listed as a carcinogen by ACGIH, IARC, NTP, or

                    CA Prop 65.







         Section 12 鈥? Environmental information





Not available







          Section 13 鈥? Disposal Consideration





Dissolve or mix the material with a combustible solvent and burn in a chemical incinerator equipped with an

afterburner and scrubber. Observe all federal, state and local environmental regulations.







          Section 14 鈥? Transport Information





IATA:           No data available

IMO:            No data available

RID/ADR:        No data available







          Section 15 鈥? Regulatory Information





European/International Regulations

    European Labeling in Accordance with EC Directives







                                                      3

                                                                                          SHANGHAI PI CHEMICALS LTD.





     Hazard Symbols: Xi

     Indication of Danger: Irritant

     Risk Phrases:

          R 22 Harmful if swallowed.

     Safety Phrases:

          S 24/25 Avoid contact with skin and eyes..

     WGK (Water Danger/Protection)

          CAS#3770-50-1: 3

     Canada

          CAS#3770-50-1: Not available

US Federal

     TSCA

          CAS# 3770-50-1 is not listed on the TSCA Inventory. It is for research and development use only.





            Section 16 鈥? Additional Information





MSDS Creation Date:             July 27, 2007

Update:                         Original









The above information is believed to be accurate and represents the best knowledge available to us currently. However,

we make no warranty of merchantability or any other warranty, express or implied, with respect to such information, and

we assume no liability resulting from its use. Users should make their own investigations to determine the suitability of the

information for their particular purposes. In no way shall PI Chemicals, be liable for any claims, losses, or damages of any

third party or for lost profits or any special, indirect, incidental, consequential or exemplary damages, even if PI Chemicals

has been advised of the possibility of such damages.









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