EMS PRODUCT: Toluene
DATE: January 1, 2000
PAGE NUMBER: One of 7
MATERIAL SAFETY DATA SHEET
The information contained herein is based on data considered
accurate. However, no warranty is expressed or implied
regarding the accuracy of these data or the results to be
obtained from the use thereof.
Electron Microscopy Sciences assumes no responsibility for
personal injury or property damage to vendees, users or
third parties caused by the material. Such vendees or users
assume all risks associated with the use of the material.
ELECTRON MICROSCOPY SCIENCES
321 MORRIS ROAD
P.O. BOX 251
FORT WASHINGTON, PA 19034 24 HOUR EMERGENCY PHONE NUMBER
(215) 646-1566 CHEMTREC: (800) 424-9300
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FOR PRODUCT AND SALES INFORMATION
_________________________________________________________________
CONTACT ELECTRON MICROSCOPY SCIENCES OFFICE ABOVE.
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PRODUCT IDENTIFICATION
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COMMON NAME: Toluene
COMMERCIAL NAME(S): Toluol
SYNONYM: Methylbenzene
CHEMICAL NAME: Toluene
CHEMICAL FAMILY: Not available.
CHEMICAL FORMULA: C6H5CH3
CAS#: 108-88-3
RTECS: XS5250000
TSCA: TSCA 8(b) INVENTORY: Toluene
CI#: Not available.
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COMPOSITION AND INFORMATION ON INGREDIENTS
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NAME: Toluene
CAS#: 108-88-3
TWA (mg/m3): 188
% BY WEIGHT: 100
TOXICOLOGICAL DATA ON INGREDIENTS:
ORAL (LD50): Acute 636 mg/kg [Rat]. 2600 mg/kg [Rat].
DERMAL (LD50): Acute 14100 mg/kg [Rabbit].
VAPOR (LC50): Acute: 49000 ppm 4 hour(s) [Rat].
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HAZARDS IDENTIFICATION
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POTENTIAL ACUTE HEALTH EFFECTS:
Very hazardous in case of ingestion. Hazardous in case of
skin contact (irritant), of eye contact (irritant), of
inhalation. Slightly hazardous in case of skin contact
(permeator).
POTENTIAL CHRONIC HEALTH EFFECTS:
CARCINOGENIC EFFECTS: Not available.
MUTAGENIC EFFECTS: Not available.
TERATOGENIC EFFECTS: Not available.
DEVELOPMENTAL TOXICITY: Not available.
The substance is toxic to the lungs, the nervous system,
mucous membranes. Repeated or prolonged exposure to the
substance can produce target organs damage.
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FIRST AID MEASURES
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EYE CONTACT:
Check for and remove any contact lenses. Immediately flush
eyes with running water for at least 15 minutes, keeping
eyelids open. Cold water may be used. Do not use an eye
ointment. Seek medical attention.
SKIN CONTACT:
After contact with skin, wash immediately with plenty of
water. Gently and thoroughly wash the contaminated skin
with running water and non-abrasive soap. Be particularly
careful to clean folds, crevices, creases and groin. Cover
the irritated area with an emollient. If irritation
persists, seek medical attention. Wash contaminated
clothing before reusing.
SERIOUS SKIN CONTACT:
Wash with a disinfectant soap and cover the contaminated
skin with an anti-bacterial cream. Seek immediate medical
attention.
INHALATION:
Allow the victim to rest in a well ventilated area. Seek
immediate medical attention.
SERIOUS INHALATION:
Evacuate the victim to a safe area as soon as possible.
Loosen tight clothing such as a collar, tie, belt or
waistband. If the victim is not breathing, perform
mouth-to-mouth resuscitation. Seek immediate medical
attention.
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INGESTION:
Do not induce vomiting. Examine the lips and mouth to
ascertain whether the tissues are damaged, a possible
indication that the toxic material was ingested; the absence
of such signs, however, is not conclusive. Loosen tight
clothing such as a collar, tie, belt or waistband. If the
victim is not breathing, perform mouth-to-mouth
resuscitation. Seek immediate medical attention.
SERIOUS INGESTION: Not available.
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FIRE AND EXPLOSION DATA
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FLAMMABILITY OF THE PRODUCT: Flammable.
AUTO-IGNITION TEMPERATURE: 480oC (896oF)
FLASH POINTS: CLOSED CUP: 4.4oC (39.9oF) (Setaflash)
OPEN CUP: 12.78oC (55oF)
FLAMMABLE LIMITS: Lower: 1.2%
Upper: 7.1%
PRODUCTS OF COMBUSTION: These products are carbon oxides (CO, CO2).
FIRE HAZARDS IN PRESENCE OF VARIOUS SUBSTANCES: Flammable in
presence of open flames and sparks.
EXPLOSION HAZARDS IN PRESENCE OF VARIOUS SUBSTANCES:
RISKS OF EXPLOSION OF THE PRODUCT IN PRESENCE OF MECHANICAL
IMPACT: Not available.
RISKS OF EXPLOSION OF THE PRODUCT IN PRESENCE OF STATIC
DISCHARGE: Not available.
FIRE FIGHTING MEDIA AND INSTRUCTIONS: Flammable liquid, soluble
or dispersed in water.
SMALL FIRE: Use DRY chemical powder.
LARGE FIRE: Use alcohol foam, water spray or fog.
SPECIAL REMARKS ON FIRE HAZARDS: Not available.
SPECIAL REMARKS ON EXPLOSION HAZARDS: Not available.
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ACCIDENTAL RELEASE MEASURES
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SMALL SPILL:
Absorb with an inert material and put the spilled material
in an appropriate waste disposal.
LARGE SPILL:
Flammable liquid.
Keep away from heat. Keep away from sources of ignition.
Stop leak if without risk. Absorb with DRY earth, sand or
other non-combustible material. Do not touch spilled
material. Prevent entry into sewers, basements or confined
areas; dike if needed. Eliminate all ignition sources. Be
careful that the product is not present at a concentration
level above TLV. Check TLV on the MSDS and with local
authorities.
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HANDLING AND STORAGE
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PRECAUTIONS:
Keep away from heat. Keep away from sources of ignition.
Ground all equipment containing material. Do not ingest.
Do not breathe gas/fumes/vapor/spray. Wear suitable
protective clothing. In case of insufficient ventilation,
wear suitable respiratory equipment. If ingested, seek
medical advice immediately and show the container or the
label. Avoid contact with skin and eyes.
STORAGE:
Flammable materials should be stored in a separate safety
storage cabinet or room. Keep away from heat. Keep away from
sources of ignition. Keep container tightly closed. Keep in a
cool, well-ventilated place. Ground all equipment containing
material. A refrigerated room would be preferable for materials
with a flash point lower than 37.8oC (100oF)
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EXPOSURE CONTROLS/PERSONAL PROTECTION
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ENGINEERING CONTROLS:
Provide exhaust ventilation or other engineering controls to
keep the airborne concentrations of vapors below their
respective threshold limit value. Ensure that eyewash
stations and safety showers are proximal to the work-station
location.
PERSONAL PROTECTION:
Splash goggles. Lab coat. Vapor respirator. Be sure to use
an approved/certified respirator or equivalent. Gloves.
PERSONAL PROTECTION IN CASE OF A LARGE SPILL:
Splash goggles. Full suit. Vapor respirator. Boots.
Gloves. A self contained breathing apparatus should be used
to avoid inhalation of the product. Suggested protective
clothing might not be sufficient; consult a specialist
BEFORE handling this product.
EXPOSURE LIMITS:
TWA: 50 (ppm) from ACGIH (TLV)[1995].
TWA: 188(mg/m3) from ACGIH [1995].
Consult local authorities for acceptable exposure limits.
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PHYSICAL AND CHEMICAL PROPERTIES
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PHYSICAL STATE AND APPEARANCE: Liquid
ODOR: Not available.
TASTE: Not available.
COLOR: Not available.
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MOLECULAR WEIGHT: 92.14 g/mole
pH (1% SOLN/WATER): Not available.
BOILING POINT: 110.6oC (231.1oF)
MELTING POINT: -95oC (-139oF)
CRITICAL TEMPERATURE: Not available.
SPECIFIC GRAVITY: 0.8661 (Water = 1)
VAPOR PRESSURE: 21.9 mm of Hg (@20oC)
VAPOR DENSITY: 3.18 (Air = 1)
VOLATILITY: Not available.
ODOR THRESHOLD: 1.6 ppm
WATER/OIL DIST. COEFF.: The product is equally soluble in oil and
water; log(oil/water)=0
IONICITY (IN WATER): Not available.
DISPERSION PROPERTIES: Not available.
SOLUBILITY: Very slightly soluble in cold water.
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STABILITY AND REACTIVITY DATA
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STABILITY: The product is stable.
INSTABILITY TEMPERATURE: Not available.
CONDITIONS OF INSTABILITY: Not available.
INCOMPATIBILITY WITH VARIOUS SUBSTANCES: Not available.
CORROSIVITY: Non-corrosive in presence of glass.
SPECIAL REMARKS ON REACTIVITY: Not available.
SPECIAL REMARKS ON CORROSIVITY: Not available.
POLYMERIZATION: No.
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TOXICOLOGICAL INFORMATION
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ROUTES OF ENTRY: Eye contact. Inhalation. Ingestion.
TOXICITY TO ANIMALS:
WARNING: THE LC50 VALUES HEREUNDER ARE ESTIMATED ON THE
BASIS OF A 4-HOUR EXPOSURE.
Acute oral toxicity (LD50): 636 mg/kg [Rat].
Acute dermal toxicity (LD50): 14100 mg/kg [Rabbit].
Acute toxicity of the vapor (LC50): 49000 ppm 4 hour(s)[Rat].
CHRONIC EFFECTS ON HUMANS: The substance is toxic to lungs, the
nervous system, mucous membranes.
OTHER TOXIC EFFECTS ON HUMANS:
Very hazardous in case of ingestion.
Hazardous in case of skin contact (irritant), of inhalation.
Slightly hazardous in case of skin contact (permeator).
SPECIAL REMARKS ON TOXICITY TO ANIMALS: Not available.
SPECIAL REMARKS ON CHRONIC EFFECTS ON HUMANS:
Detected in maternal milk in human. Passes through the
placental barrier in human. Embryotoxic and/or foetotoxic
in animal.
SPECIAL REMARKS ON OTHER TOXIC EFFECTS ON HUMANS: Not available.
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ECOLOGICAL INFORMATION
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ECOTOXICITY: Not available.
BOD5 AND COD: Not available.
PRODUCTS OF BIODEGRADATION: Possibly hazardous short term
degradation products are not likely. However, long term
degradation products may arise.
TOXICITY OF THE PRODUCTS OF BIODEGRADATION: The products of
degradation are more toxic.
SPECIAL REMARKS ON THE PRODUCTS OF BIODEGRADATION: Not available.
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DISPOSAL CONSIDERATIONS
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WASTE DISPOSAL: Recycle to process, if possible. Consult your
local or regional authorities.
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TRANSPORT INFORMATION
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DOT CLASSIFICATION: CLASS 3: Flammable liquid.
IDENTIFICATION: Toluene UN1294 PG:II
SPECIAL PROVISIONS FOR TRANSPORT: Not available.
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OTHER REGULATORY INFORMATION
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FEDERAL AND STATE REGULATIONS:
CALIFORNIA PROPOSITION 65: This product contains the
following ingredients for which the State of California has
found to cause cancer, birth defects or other reproductive
harm, which would require a warning under the statute:
TOLUENE
CALIFORNIA PROPOSITION 65: This product contains the
following ingredients for which the State of California has
found to cause birth defects which would require a warning
under the statute: TOLUENE
PENNSYLVANIA RTK: Toluene
MASSACHUSETTS RTK: Toluene
TSCA 9(B) INVENTORY: Toluene
SARA 313 TOXIC CHEMICAL NOTIFICATION AND RELEASE REPORTING:
Toluene
CERCLA: HAZARDOUS SUBSTANCES: Toluene
OTHER REGULATIONS:
OSHA: Hazardous by definition of Hazard Communication
Standard (29 CFR 1910.1200).
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OTHER CLASSIFICATIONS:
WHMIS (CANADA): CLASS B-2: Flammable liquid with a flash
point lower than 37.8oC (100oF).
CLASS D-2A: Material causing other toxic
effects (VERY TOXIC).
DSCLA (EEC): R11-Highly Flammable.
R36/38-Irritating to eyes and skin.
HMIS (U.S.A.):
HEALTH HAZARD: 2
FIRE HAZARD: 3
REACTIVITY: 0
PERSONAL PROTECTION: h
NATIONAL FIRE PROTECTION ASSOCIATION (U.S.A.)
HEALTH: 2
FLAMMABILITY: 3
REACTIVITY: 0
SPECIFIC HAZARD:
PROTECTIVE EQUIPMENT:
Gloves.
Lab coat.
Vapor respirator. Be sure to use an approved/certified
respirator or equivalent. Wear appropriate respirator
when ventilation is inadequate.
Splash goggles.
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