EMS CATALOG NO: 26052-05
EMS PRODUCT: SCHIFF鈥橲 REAGENT
DATE: 09/18/2007
PAGE NUMBER: One of 5
MATERIAL SAFETY DATA SHEET
The information contained herein is based on data considered
accurate. However, no warranty is expressed or implied
regarding the accuracy of these data or the results to be
obtained from the use thereof.
Electron Microscopy Sciences assumes no responsibility for
personal injury or property damage to vendees, users or
third parties caused by the material. Such vendees or users
assume all risks associated with the use of the material.
ELECTRON MICROSCOPY SCIENCES
1560 INDUSTRY ROAD
P.O. BOX 550
HATFIELD, PA 19440 24 HOUR EMERGENCY PHONE NUMBER
(215) 412-8400 CHEMTREC: (800) 424-9300
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FOR PRODUCT AND SALES INFORMATION
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CONTACT ELECTRON MICROSCOPY SCIENCES OFFICE ABOVE.
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PRODUCT IDENTIFICATION
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PRODUCT NAME: Schiff's Reagent
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HAZARDOUS INGREDIENTS/IDENTITY INFORMATION %(optional)
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BASIC FUCHSIN, CERTIFIED: (C19H17N3) CAS # 569-61-9 0.45%
RTECS No.: CX9850100 C.I. 42500
SYNONYMS: Basic parfuchsine: calcozine magenta N;
Basic Red; Fuchsin SP; Benzenamine; 4 -
((4-aminophenyl)
(4-Imino-2,5-cyclotexadeim-1-ylidenemethyl)
monohydrochloride.
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TOXICITY: ORL-mus LD50; 5000mg/kg
BASIC FUCHSIN IS A CANCER SUSPECT AGENT!!!!!!
HYDROCHLORIC ACID, CONC. (HCL) CAS# 7647-01-0 0.75%
RTECS NO.: MW4025000
SYNONYMS: Muritic acid; chlorohydric acid; hydrochloride
THRESHOLD LIMIT VALUE (tlv/twa): 7mg/M3 (5ppm)
PERMISSIBLE: EXPOSURE LIMIT (PEL): 7mg/M3 (5pmm)
TOXICITY: LD50 (ORL-rbt)(mg/kg) - 900
LD50 (IPR-mus)(mg/kg) - 40
LD50 (INHL-rat)(mg/kg) - 3124
SODIUM BISULFITE, (A.C.S. REAGENT) (HNaO3S) CAS# 7631-90-5
0.45%
RTECS NO.: VZ2000000
SYNONYMS: Hydrogen sulfite sodium" NA2693 (DOT) Sodium Acid
sulfite; sodium hydrogen sulfite; sodium sulhydrate;
sulfurous acid;monosodium salt
TOXICITY DATA: ORL-rat LD50:2gm/kg IPR-rat LD50:475mg/kg
IVN-rat LD50:115mg/kg IPR-mus LD50:675mg/kg
IVN-mus LD50:130mg/kg IPR-dog LD50:24mg/kg
IPR-rbt LD50:300mg/kg IVN-rbt LD50:65mg/kg
IVN-gpg LD50:779mg/kg IPR-ham LD50:487mg/kg
IVN-ham LD50:95mg/kg
ACHIH TLV-TWA 5mg/M3
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PHYSICAL/CHEMICAL CHARACTERISTICS
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Boiling Point: N/A Specific Gravity (H2O=1):N/A
Vapor Pressure (mmHg.): N/A Melting Point: N/A
Vapor Density (AIR=1): N/A Evaporation rate: N/A
(Butyl acetate=1)
Solubility in Water: Yes
Appearance and Odor: Colorless to straw yellow solution: sulfur
dioxide smell.
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FIRE AND EXPLOSION HAZARD DATA
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FLASH POINT (Method Used): N/A
FLAMMABLE LIMITS: N/A LEL: UEL:
EXTINGUISHING MEDIA:
Use extinguishing media appropriated for surrounding fire.
Firefighters should wear proper protective clothing and
self-contained breathing apparatus operated in positive
pressure mode.
SPECIAL FIRE FIGHTING PROCEDURES:
Move containers from fire if it can be done so without risk. Use
water to keep fire exposed containers cool. May emit hydrogen
gas. Upon contact with metal, may produce toxic gases, hydrogen
chloride, hydrogen gas.
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REACTIVITY DATA
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UNSTABLE __ ___ STABLE ____x__
CONDITIONS TO AVOID: Liberates toxic fumes of sulfur dioxide.
INCOMPATIBILITY (Materials to Avoid): N/A
HAZARDOUS DECOMPOSITION OR BYPRODUCTS: CO, CO脳, HCL GAS
HAZARDOUS POLYMERIZATION: WILL NOT OCCUR
CONDITIONS TO AVOID: N/A
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HEALTH HAZARD DATA
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ROUTE(S) OF ENTRY:
Inhalation?: Yes Skin?: Yes Ingestion?: Yes
HEALTH HAZARDS (Acute and Chronic):
Inhalation may cause pulmonary edema, damage to upper respiratory
system, coughing and difficulty breathing. Causes irritation to
skin and eyes. May cause headache, nausea, vomiting and
diarrhea. Repeated exposure may cause allergic reactions in
certain individuals.
CARCINOGENICITY:
NTP?: NO IARC Monographs?: YES OSHA Regulated?: NO
SIGNS AND SYMPTOMS OF EXPOSURE:
Irritant to skin, eyes & respiratory tract. Harmful if swallowed.
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BASIC FUCHSIN IS A CANCER SUSPECT AGENT!
MEDICAL CONDITIONS GENERALLY AGGRAVATED BY EXPOSURE:
Individuals with asthma may experience hypersensitivity to
sulfites and bronco spasm, gastrointestinal disturbances,
flushing and tingling sensation and shock.
EMERGENCY AND FIRST AID PROCEDURES:
EYES: CALL A PHYSICIAN! Flush eyes with plenty of water for at
least 15 minutes.
SKIN: Flush with plenty of water for at least 15 minutes.
INHALATION: Remove to fresh air. If not breathing and unconscious
give artificial respiration. CALL A PHYSICIAN!
INGESTION: Wash mouth out with water provided person is conscious.
CALL A PHYSICIAN!
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PRECAUTIONS FOR SAFE HANDLING AND USE
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STEPS TO BE TAKEN IN CASE MATERIAL IS RELEASED OR SPILLED:
Wearing proper protective gear, cover spill area with soda ash or
Sodium Bicarbonate. Scoop into a beaker and dilute with water. If
effervescent, wait until reaction is complete. Cautiously add an
equal volume of calcium hypoclorite (reaction may be vigorous) add
more water, stir and allow to stand for one hour. Dilute and
containerize for proper disposal.
WASTE DISPOSAL METHOD:
In accordance with all current local, state and federal environmental
regulations.
PRECAUTIONS TO BE TAKEN IN HANDLING AND STORAGE:
Store in refrigerator. Keep container well sealed. Avoid contact
with skin, eyes and clothing. Do not breathe vapors; use with
adequate ventilation. Wash thoroughly after handling.
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CONTROLS MEASURES
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RESPIRATORY PROTECTION (SPECIFY TYPE):
A NIOSH approved respirator with organic vapor cartridge.
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VENTILATION: Local Exhaust: Special:
Mechanical (General): Fume Hood Other:
PROTECTIVE GLOVES:
Rubber Gloves Eye Protection: Face shield w/goggles
OTHER PROTECTIVE CLOTHING OR EQUIPMENT:
Approved work clothes
WORK/HYGIENIC PRACTICES:
Use care when handling! Avoid all routes of exposure!
TRANSPORT INFO FOR SCHIFF'S REAGENT:
There are no special shipping instructions other than this product
must be packaged in glass.
Dot: Non-Restricted
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