Material Safety Data Sheet
MSDS Number: 98
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LIBERTY ATZ HERBICIDE MSDS Version 1.1
SECTION 1. CHEMICAL PRODUCT AND COMPANY INFORMATION
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Product Name LIBERTY ATZ HERBICIDE
Chemical Name active ingredients: glufosinate-ammonium and atrazine
Synonym
MSDS Number 98
Chemical Family
Chemical Formulation
EPA Registration No. 264-668
Canadian Registrat. No.
Aventis CropScience USA LP
2 T.W. Alexander Drive
Research Triangle PK, NC 27709
USA
For Product Use Information: (888)-AVENTIS (283-6847) Monday through Friday
8:00AM-4:30PM
For Medical Emergency contact DART: (800) 334-7577 24 Hours/Day
For Transportation Emergency CHEMTREC: (800) 424-9300 24 Hours/Day
Product Use Description Liberty ATZ Herbicide is a selective herbicide for use only on corn resistant to
glufosinate-ammonium. Aventis recommends use only on seed designated as
Liberty Link or warranted by Aventis as being resistant to glufosinate-ammonium.
SECTION 2. COMPOSITION/INFORMATION ON INGREDIENTS
Component Name CAS No. Concentration % by Weight
Minimum Maximum
Glufosinate-ammonium 77182-82-2 10.0000
ATRAZINE 1912-24-9 31.7500
Related compounds 1.6700
Other ingredients, including: 0-08-8 56.5800
Sodium laureth sulfate 68585-34-2
Lignosulfonic acid, sodium salt, sulfomethylated 68512-34-5
Sodium xylenesulfonate 1300-72-7
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Material Safety Data Sheet
MSDS Number: 98
LIBERTY庐 ATZ HERBICIDE MSDS Version 1.1
SECTION 3. HAZARDS IDENTIFICATION
NOTE: Please refer to Section 11 for detailed toxicological information.
Emergency Overview Harmful if swallowed. Causes moderate eye irritation. Toxic to fish and aquatic
invertebrates.
Physical State liquid
Odor Odorless to fatty/oily-like odor.
Appearance A light to medium brown
Immediate Effects
Eye Causes moderate eye irritation.
Ingestion Harmful if swallowed.
Inhalation Harmful if inhaled.
Chronic or Delayed This product contains atrazine which has been shown to produce tumors in
Long-Term certain strains of rats. See Section 11 for further information.
Signs and Symptoms Nausea, vomiting, diarrhea, increased salivation, drowsiness, tremors,
convulsions, respiratory depression, cardiac arrhythmia, decreased blood
pressure, drowsiness and/or loss of consciousness. These symptoms may be
delayed by up to 48 hours after exposure.
SECTION 4. FIRST AID MEASURES
Eye Flush eyes with plenty of water. Get medical attention if irritation persists.
Skin Wash with plenty of soap and water.
Ingestion Rinse mouth thoroughly with plenty of water. Do NOT induce vomiting. Get
medical attention immediately.
Inhalation Remove individual to fresh air. Get medical attention if breathing difficulty
develops.
Note to Physician Symptoms may be delayed by up to 48 hours following ingestion. Thus, a patient
ingesting undiluted product treated as outlined below. Treatment should be
symptomatic and supportive.
In addition, the following procedures are generally recommended:
If ingested, endotracheal intubation and gastric lavage should be performed as
soon as possible, followed by charcoal and sodium sulfate administration.
Respiratory, Cardiac and Central Nervous Systems should be monitored with
particular regard to ECG, electrolyte balance (especially for potassium) and
signs of increased intracranial pressure.
In the event of a large exposure, dialysis and/or hemoperfusion should be
conducted as soon as possible to eliminate the compound from the body. In the
event of convulsions, administer phenobarbital or diazepam.
There is no specific antidote. Glufosinate-ammonium does not inhibit
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Material Safety Data Sheet
MSDS Number: 98
LIBERTY庐 ATZ HERBICIDE MSDS Version 1.1
cholinesterase; thus atropine and 2-PAM are contraindicated. Recovery is
normally spontaneous, usually within 48 hours.
SECTION 5. FIRE FIGHTING MEASURES
Flash Point > 93 掳C / > 199 掳F
Closed cup
Suitable Extinguishing Dry chemical, foam or carbon dioxide.
Media
Fire Fighting As in any fire, wear self-contained breathing apparatus pressure-demand,
Instructions MSHA/NIOSH approved (or equivalent) and full protective gear. Keep upwind.
Isolate hazard area. Avoid inhalation of smoke and fumes. Use water or foam to
reduce fumes. Do not touch spilled material. If possible, move containers from
area. Extinguish only if flow can be stopped. Use flooding amounts of water as a
fog. Cool containers with flooding amounts of water from as far a distance as
possible. Avoid breathing vapors.
FLAMMABILITY CLASSIFICATION/RATING:
NFPA/OSHA Class: IIIB
NFPA Rating (Fire): 1
SECTION 6. ACCIDENTAL RELEASE MEASURES
General and Disposal Use proper protective equipment to minimize personal exposure (see Section 8).
Take all necessary action to prevent and to remedy the adverse effect of the
spill. Ensure that the disposal is in compliance with all Federal, State/Provincial,
and local regulations (See Section 13 for applicable RCRA Number). Refer to
Section 15 for applicable Reportable Quantity (RQ) and other regulatory
requirements.
Land Spill or Leaks Small Spills: Absorb with an inert absorbent material such as granular clay, saw
dust, or pet litter. Sweep up carefully while avoiding the formation of a dust
cloud. Place in an approved chemical waste container for disposal. Rinse spill
area with small amount of soapy water. Contain and absorb the rinsate with inert
absorbents and place into the same disposal container. Area can be washed
with water to remove the last trace residue. Do not allow water to contaminate
water supplies or sewers.
Large Spills: Eliminate all ignition sources. Stop leak if you can do so without
coming into contact with spilled material. Dike far ahead of liquid spill for later
disposal. All equipment used to clean up spill should be grounded. Prevent entry
into waterways, sewers, basements or confined areas. Inform appropriate
authorities immediately if contamination occurs. Contact Aventis for further
assistance if necessary.
SECTION 7. HANDLING AND STORAGE
Handling Procedures Avoid contact with skin, eyes or clothing.
Avoid breathing vapor or spray mist.
Storing Procedures Do not contaminate water, food or feed by storage.
Store in a cool, dry place inaccessible to children and pets.
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Material Safety Data Sheet
MSDS Number: 98
LIBERTY庐 ATZ HERBICIDE MSDS Version 1.1
Work/Hygienic Wash hands thoroughly with soap and water after handling and before eating,
Procedures drinking, chewing gum, using tobacco, or using the toilet.
Remove clothing immediately if pesticide gets inside. Then wash thoroughly and
put on clean clothing.
Remove PPE immediately after handling this product. Wash the outside of
gloves before removing. As soon as possible, wash thoroughly and change into
clean clothing.
SECTION 8. EXPOSURE CONTROLS/PERSONAL PROTECTION
Engineering Controls Control airborne concentrations below the appropriate exposure guideline (see
below for any applicable OSHA/ACGIH Exposure Limits). Local exhaust
ventilation may be necessary.
Eye/Face Protection Wear safety glasses, splash goggles or face shield.
Body Protection Wear chemical-resistant gloves (Neoprene, Nitrile, PVC) and other protective
clothing to avoid skin contact.
Respiratory Protection Ensure good ventilation. If not adequate, use a chemical cartridge-type respirator
approved by the National Institute of Occupationa l Health and Safety.
General Protection Eye wash facility and safety shower should be available.
AGRICULTURAL USES:
The following personal protective equipment (PPE) must be worn when using product or upon early entry into
treated areas during the Restricted Entry Interval (REI):
Long sleeved shirt and long pants; or Coveralls (required for REI only)
Chemical-resistant gloves
Shoes and socks
Protective eyewear
Chemical-resistant apron during mixing and loading
See "User Safety Recommendations" on the product label for additional details concerning the use of PPE
under the EPA Worker Protection Standards (40 CFR Part 170).
Exposure Limits
ATRAZINE 1912-24-9 ACGIH TWA 5 mg/m3
NIOSH REL 5 mg/m3
OSHA Z1A TWA 5 mg/m3
US CA OEL TWA PEL 5 mg/m3
SECTION 9. PHYSICAL AND CHEMICAL PROPERTIES
Appearance A light to medium brown
Physical State liquid
Odor Odorless to fatty/oily-like odor.
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Material Safety Data Sheet
MSDS Number: 98
LIBERTY庐 ATZ HERBICIDE MSDS Version 1.1
pH 6.8 19.2 掳C
Vapor Pressure Not available
Vapor Density (air = 1) Not available
Specific Gravity 1.138 g/cm3
at 20 掳C
Boiling Point Not available
Melting/Freezing Point Not available
Solubility (in water) Not available
Solubility (in Solvent/Oil) Not available
Minimum Ignition Energy Not available
(mj)
Minimum Explosion Not available
Conc. (MEC)
Other Information EVAPORATION RATE (BUTYL ACETATE = 1): Not available
DUST EXPLOSION SEVERITY DATA: Not applicable
LIMITED OXYGEN CONCENTRATION (LOC): Not available
SECTION 10. STABILITY AND REACTIVITY
Chemical Stability Stable
Incompatibility None known.
Hazardous Will not occur
Polymerization
(Conditions to avoid)
SECTION 11. TOXICOLOGICAL INFORMATION
Acute Oral Toxicity Rat: LD50: 2,119 mg/kg
Slightly toxic
Acute Dermal Toxicity Rat: LD50: > 5,319 mg/kg
Practically non-toxic
Acute Inhalation Toxicity Female Rat: LC50: > 2.09 mg/l 4 h
Practically non-toxic
Male Rat: LC50: 4 h
Slightly toxic
> 0.57 mg/l and < 2.09 mg/l
Skin Irritation Rabbit: Non-irritating
Primary irritation index = 0.13/8.0
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Material Safety Data Sheet
MSDS Number: 98
LIBERTY庐 ATZ HERBICIDE MSDS Version 1.1
Eye Irritation Rabbit: Slightly irritating.
Max. Avg. Score = 18.5/110
Sensitization Guinea pig: Non-sensitizing
THE ABOVE DATA WAS DEVELOPED WITH: a similar formulation as Liberty ATZ Herbicide.
NOTE: The severity classifications listed above are those of Aventis, and, particularly for eye irritation, may not
always coincide with EPA-mandated Precautionary Statements.
THE FOLLOWING INFORMATION ON ATRAZINE WAS OBTAINED FROM NOVARTIS, THE
MANUFACTURER OF THIS INGREDIENT. FOR FURTHER INFORMATION ON THIS ACTIVE
INGREDIENT, PLEASE CONTACT NOVARTIS.
Chronic Toxicity Glufosinate-ammonium Technical:
No clear evidence of target organ toxicity was noted in studies with rats, mice or
dogs. An adaptive increase in kidney weight was noted in several species but no
functional or histopathological changes were observed. No-Observable-Effect-
Levels (NOEL's) for the 1-year dog, 2.5-year rat and 2-year mouse studies were
approximately 5 mg/kg/day, 2.1 mg/kg/day and 14 mg/kg/day, respectively.
Glufosinate-ammonium was not carcinogenic in either rats or mice.
Atrazine:
Long term exposure to low levels of Atrazine is not known to cause any chronic
ill effects in humans. An elevated incidence of mammary tumors was
noted/observed in female Sprague-Dawley rats during a long-term feeding study
with Atrazine Technical. This response did not occur in male Sprague-Dawley
rats, F-344 male or female rats, or mice and is considered to be sex and strain
specific. In other long-term feeding studies, very high doses of Atrazinecaused
signs of cardiotoxicity in dogs and mice. Ametabolite of Atrazine, 2,3-diamino-6-
chloro-s-traizine(DACT) has caused cardiotoxicity in dogs at high doses.
Atrazine is classified by IARC as a possible human carcinogen (Group 2B;
human evidence is inadequate, animal evidence is limited).
Assessment Carcinogenicity
ACGIH
ATRAZINE 1912-24-9 Group A4
NTP
None
IARC
ATRAZINE 1912-24-9
OSHA
None
Reproductive & Glufosinate-ammonium Technical:
Developmental Toxicity Evidence of developemntal toxicity was noted in rats but only at dose levels that
were also toxic to the mother. No developmental toxicity was noted in rabbits.
The maternal and developmental NOEL's were considered to be 10 and 50
mg/kg/day, respectively, in rats; and 6.3 and 20 mg/kg/day (highest dose tested),
respectively, in rabbits. The parental and reproductive NOEl's in a 2-generation
rat reproductive study were considered to be 40 ppm (approximately 4
mg/kg/day) and 120 (approximately 12 mg/kg/day), respectively, based on
decreased kidney weights at 120 ppm and decreased litter size at 360 ppm.
Atrazine:
Atrazine caused no adverse reproductive effects over two generations of rats.
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Material Safety Data Sheet
MSDS Number: 98
LIBERTY庐 ATZ HERBICIDE MSDS Version 1.1
Neurotoxicity Glufosinate-ammonium Technical:
Glufosinate-ammonium does not inhibit acetycholinesterase activities. No
evidence of delayed neurotoxicity was noted in hens. Neurobehavioral effects
(e.g., hypersensitivity, tremors, convulsions) related to stimulation of the central
nervous system (CNS) were observed in some studies but only at lethal or near
lethal dose levels.
Teratogenicity Glufosinate-ammonium Technical:
No evidence of teratogenicity was noted in either rats or rabbits.
Atrazine:
Atrazine was not teratogenic in rats or rabbits.
Mutagenicity Glufosinate-ammonium Technical:
No evidence of mutagenicity or other gentic effects was noted in a battery of in
vitro or in vivo studies.
Atrazine:
Atrazine has been reported to cause mutagenic effects in barley seeds and corn
plants, however, those findings have been sucesssfully refuted, and weight-of-
evidence evaluation of data from studies documented as reliable in determining
mutagenic potential indicate that Atrazine is not a mutagen.
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Material Safety Data Sheet
MSDS Number: 98
LIBERTY庐 ATZ HERBICIDE MSDS Version 1.1
SECTION 12. ECOLOGICAL INFORMATION
Environmental (1) Do not mix or load this product within 50 feet of any streams, rivers, lakes or
Precautions reservoirs.
(2) Do not mix or load this product, or rinse or wash containers within 50 feet of
any well or sink hole unless conducted on an impervious, self-contained pad
designed and maintained to contain any product spills or leaks, equipment rinse
or washwater, and rain water that may fall on the pad.
(3) Do not apply this product directly to water, areas where surface water is
present, or intertidal areas below the mean high water mark; or within 50 feet of
any well, sink hole, intermittent or perennial stream, river, lake or reservoir.
(4) Do not apply this product to well-drained or very permeable sand or loamy
soils where the water table (ground water) is very close to the surface.
(5) Do not apply this product within 66 feet of the points where field surface
water runoff enters perennial or intermittent streams and rivers or within 200 ft.
around natural or impounded lakes and reservoirs. If this product is applied to
highly erodible land, the 66-ft. buffer or setback from runoff entry points must be
planted to crop, seeded with grass, or other suitable crop.
(6) Do not apply when weather conditions favor drift from treated areas.
(7) Do not contaminate water when disposing of equipment washwaters.
(8) See product label for further information.
Ecological Information No ecological toxicity data have been developed specifically with this product.
However, based on other data, Liberty ATZ Herbicide is expected to be
practically non-toxic to birds and slightly to moderately toxic to fish and aquatic
invertebrates.
Glufosinate-ammonium Technical:
Aquatic
Acute Freshwater Fish & Invertebrates (LC50 or EC50): 560 to > 1000 mg/l
Acute Marine & Estuarine Organisms (LC50 or EC50): 7.2 to > 125 mg/l
Chronic Freshwater Invertebrate (NOEC): 32 mg/l
Aquatic Plants (EC50 or IC50): 1 to > 1000 mg/l
Avian
Acute Oral LD50: > 2,000 mg/kg
Acute Dietary LC50: > 5,000 ppm
Reproductive NOEL: 400 ppm
Other
Honeybee (contact LD50): > 600 micrograms/bee
THE FOLLOWING INFORMATION ON ATRAZINE WAS OBTAINED FROM
NOVARTIS, THE MANUFACTURER OF THIS INGREDIENT. FOR FURTHER
INFORMATION ON THIS ACTIVE INGREDIENT, PLEASE CONTACT
NOVARTIS.
Aquatic
Acute Freshwater Fish and Invertebrates (LC50 or EC50): 4.9 to 42 mg/l
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Material Safety Data Sheet
MSDS Number: 98
LIBERTY庐 ATZ HERBICIDE MSDS Version 1.1
Fish Early Life Stage (MATC): > 0.25 to < 0.46 mg/l
Invertebrate Life Cycle (NOEC): 2.5 ppm
Avian
Acute Oral LD50: > 940 mg/kg
Acute Dietary LC50: > 5000 ppm
Reproductive NOEL: 225 ppm
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Material Safety Data Sheet
MSDS Number: 98
LIBERTY庐 ATZ HERBICIDE MSDS Version 1.1
Environmental Fate Glufosinate-ammonium Technical:
Glufosinate-ammonium is very soluble in water and is hydrolytically and
photolytically stable. Its mobility under laboratory conditions varies widely,
depending upon the soil type. However, the results of numerous terrestrial field
dissipation studies indicate that the potential for groundwater contamination is
minimal. This appears to be primarily a result of its rapid degradation by
microorganisms in the soil and a tendency to bind to certain soil elements
resulting in no measurable leaching. Glufosinate-ammonium does not
accumulate in fatty tissues of fish or other animals.
Water Solubility: 1370 g/l (pH 5, 22掳C)
Hydrolytic Half-Life: > 300 days
Photolytic Half-Life: > 300 days
Soil Half-Life: 6-23 days in field dissipation studies
Log Pow: < 0.1 (pH 7)
Koc: 10-1229 (depending upon soil type)
Bioconcentration factor (BCF): 7
Atrazine Technical:
Atrazine can leach through soil and enter ground water. Contact Novartis for
further information.
SECTION 13. DISPOSAL CONSIDERATIONS
General Disposal Do not contaminate water, food or feed by storage or disposal.
Guidance
Pesticide Disposal: Wastes resulting from the use of this product may be
disposed of on site or at an approved waste disposal facility.
Container Disposal 2 1/2 Gallon Container Only: Empty containers should be triple rinsed (or
equivalent). Then offer for recycling or reconditioning, or puncture and dispose of
in a sanitary landfill, or by incineration, or, if allowed by State and local
authorities, by burning. If burned, stay out of smoke.
15 Gallons, 60 Gallons, 120 Gallons & Bulk Containers Only: This is a sealed
returnable container to be used only for Liberty ATZ Herbicide. When this
container is empty, it must not be opened, cleaned, or discarded. Empty
containers must be returned to the original purchase location.
RCRA CLASSIFICATION:
RCRA HAZARDOUS WASTE INGREDIENTS: None
SECTION 14. TRANSPORT INFORMATION
PROPER SHIPPING NAME: Pesticides, liquid, toxic, n.o.s., (Glufosinate Ammonium and Atrazine), 6.1,
UN2902, PG III
DOT SHIPPING LABEL: Keep Away From Foodstuffs
Markings on box: Pesticides, liquid, toxic, n.o.s., UN2902, (Glufosinate Ammonium and Atrazine)
NOTE: For transport purposes (49 CFR Part 173.132), the calculated 1-Hour LC50 (Rat) is: > 2.28 mg/l and <
8.36 mg/l.
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Material Safety Data Sheet
MSDS Number: 98
LIBERTY庐 ATZ HERBICIDE MSDS Version 1.1
SECTION 15. REGULATORY INFORMATION
US Federal
EPA Registration No. 264-668
TSCA list
ATRAZINE 1912-24-9
Sodium laureth sulfate 68585-34-2
Lignosulfonic acid, sodium salt, 68512-34-5
sulfomethylated
Sodium xylenesulfonate 1300-72-7
TSCA 12b export notification
None
SARA Title III - section 302 - notification and information
None
SARA Title III - section 313 - toxic chemical release reporting
ATRAZINE 1912-24-9 1.0%
US States Regulatory
CA Prop65
This product contains a chemical known to the state of California to cause cancer.
None
This product contains a chemical known to the state of California to cause birth defects or other
reproductive harm.
None
US State right-to-know ingredients
ATRAZINE 1912-24-9 CA, IL, NJ, PA, RI
Canadian Regulations
Canadian Registrat. No.
Canadian Domestic Substance List
ATRAZINE 1912-24-9
Sodium laureth sulfate 68585-34-2
Lignosulfonic acid, sodium salt, 68512-34-5
sulfomethylated
Sodium xylenesulfonate 1300-72-7
Environmental
CERCLA
None
Clean Water Section 307 Priority Pollutants
None
Safe Drinking Water Act Maximum Contaminant Levels
ATRAZINE 1912-24-9
International Regulations
EU Classification
None
European Inventory of Existing Commercial Substances (EINECS)
Glufosinate-ammonium 77182-82-2
ATRAZINE 1912-24-9
Sodium xylenesulfonate 1300-72-7
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Material Safety Data Sheet
MSDS Number: 98
LIBERTY庐 ATZ HERBICIDE MSDS Version 1.1
SECTION 16. OTHER INFORMATION
Health Flammability Reactivity Others
HMIS 3 1 0 F
NFPA 3 1 0 -
REVISED SECTIONS:
MSDS Revision Indicators: New Format.
PREPARED BY: Dept. of Regulatory Affairs
PHONE: 800-438-5837
SUPERCEDES MSDS DATED: 05/11/2000
Print Date: 12/03/2001
Supersedes MSDS, which is older than: 12/03/2001
This information is provided in good faith but without express or implied warranty. Buyer assumes all
responsibility for safety and use not in accordance with label instructions. The product names are registered
trademarks of Aventis.
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