MATERIAL SAFETY DATA SHEET
MANUFACTURER Varian Instruments 鈥? Middelburg
ADDRESS Herculesweg 8
4338 PL Middelburg, Netherlands
PHONE 31.118.67100 MSDS Number: 1002-009 Rev. 0
EMERGENCY PHONE 1.800.424.9300 鈥? CHEMTREC USA Date: April 11, 2002
FAX 31.118.633118 Prepared by: Corporate EH&S
SECTION 1: MATERIAL IDENTIFICATION
Product Name: Testmix CP0009
Synonyms: Fatty Acids in Acetone. Acetone is also known as Methyl Ketone and 2-Propanone.
SECTION 2: COMPOSITION
An ampoule/vial containing the following:
Approximate NTP IARC
Component CAS Number Concentration Carcinogen Status Carcinogen Status
C14:0 - Myristic Acid 544-63-8 0.10% not listed not listed
C16:0 - Palmitic Acid 57-10-3 0.10% not listed not listed
C16:1- Palmitoleic Acid 373-49-9 0.10% not listed not listed
C18:0 - Stearic Acid 57-11-4 0.10% not listed not listed
C18:2 - Linoleic Acid 60-33-3 0.10% not listed not listed
C20:0 - Arachidic acid 506-30-9 0.10% not listed not listed
C20:1- Gadoleic Acid 5561-99-9 0.10% not listed not listed
C18:3 - Alpha-linolenic Acid 463-40-1 0.10% not listed not listed
C22:0 - Behenic Acid 112-85-6 0.10% not listed not listed
C24:0 - Lignoceric Acid 557-59-5 0.10% not listed not listed
Acetone 67-64-1 balance not listed not listed
NOTE: Unless otherwise noted, the information below pertains only to the Acetone solvent in the ampoule/vial.
SECTION 3: HAZARD IDENTIFICATION
Emergency Overview: Colorless liquid. Flash Point: -20 deg C. Causes eye and skin irritation. May cause central nervous system
depression. May cause liver and kidney damage. Causes respiratory tract irritation. Danger! Extremely flammable liquid and
vapor. Vapor may cause flash fire. Target Organs: Kidneys, central nervous system, liver, respiratory system, eyes, and skin.
Potential Health Effects
Inhalation: Inhalation of high concentrations may cause central nervous system effects characterized by nausea, headache,
dizziness, unconsciousness and coma. Causes respiratory tract irritation. May cause liver and kidney damage. May cause motor
incoordination and speech abnormalities.
Ingestion: Swallowing small amounts is not likely to produce harmful effects. Ingestion of larger amounts may produce abdominal
pain, nausea and vomiting. Aspiration into lungs can produce severe lung damage and is a medical emergency. Other symptoms
are expected to parallel inhalation.
Skin Contact: Irritating due to defatting action on skin. Causes redness, pain, drying and cracking of the skin.
Eye Contact: Produces irritation, characterized by a burning sensation, redness, tearing, inflammation, and possible corneal injury.
Vapors are irritating to the eyes.
Carcinogen Status: NTP: Not listed IARC: Not listed
SECTION 4: FIRST AID INFORMATION
Inhalation: Get medical attention immediately. Remove to fresh air. If breathing is difficult, give oxygen. If breathing has ceased
apply artificial respiration using oxygen and a suitable mechanical device such as a bag and a mask. Do NOT use mouth-to-mouth
resuscitation.
Ingestion: If swallowed, get medical attention immediately. Do NOT induce vomiting. If victim is conscious and alert, give 2-4
cupfuls of milk or water. Never give anything by mouth to an unconscious person.
Skin Contact: In case of contact, immediately flush skin with plenty of soap and water for at least 15 minutes. Remove
contaminated clothing and shoes. Get medical attention if irritation develops or persists. Wash clothing before reuse.
Eye Contact: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical
attention immediately. Do NOT allow victim to rub or keep eyes closed.
MSDS# 1002-009 Revision 0 Effective Date 04/11/02 Page 1 of 4
SECTION 5: FIRE-FIGHTING INFORMATION
Fire: Flash point (closed cup): -20C (-4F)
Autoignition temperature: 465C (869F)
Flammable limits in air % by volume: Lower = 2.5 Upper = 12.8
NFPA Rating: health-1; flammability-3; reactivity-0
Explosion: Above flash point, vapor-air mixtures are explosive within flammable limits noted above. Vapors can flow along
surfaces to distant ignition source and flash back. Contact with strong oxidizers may cause fire. Sealed containers may rupture
when heated. This material may produce a floating fire hazard. Sensitive to static discharge.
Fire Extinguishing Media: Dry chemical, foam or carbon dioxide. Water may be ineffective. Water spray may be used to keep fire
exposed containers cool, dilute spills to nonflammable mixtures, protect personnel attempting to stop leak and disperse vapors.
SECTION 6: ACCIDENTAL RELEASE MEASURES
Use proper personal protective equipment as indicated in Section 8. Ventilate area of leak or spill. Remove all sources of ignition.
Absorb spill with inert material (e.g. vermiculite, sand or earth), scoop up with a nonsparking tool, then place into a suitable
container for disposal. Do not flush to sewer!
SECTION 7: HANDLING AND STORAGE
Handling: Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use only in a well-ventilated
area. Keep container tightly closed. Avoid contact with heat, sparks and flame. Do not get on skin or in eyes. Avoid ingestion and
inhalation.
Storage: Keep away from heat, sparks, flame and sources of ignition. Store in a tightly closed container. Store in a cool, dry, well-
ventilated area away from incompatible substances.
SECTION 8: EXPOSURE CONTROL/PERSONAL PROTECTIVE EQUIPMENT
Airborne Exposure Limits: United States - OSHA Permissible Exposure Limit (PEL): 1000 ppm (TWA)
United States - ACGIH Threshold Limit Value (TLV): 500 ppm (TWA) ; 750 ppm (STEL)
Australia: Time-weighted average 500 ppm (1185 mg/m3), Short term exposure limit 1000 ppm,
JAN1993
The Netherlands: MAC-TGG 750 ppm (1780 mg/m3), JAN1999
Personal Protective Equipment
Eye Protection: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face
protection regulations in 29 CFR 1910.133 or European Standard EN166. Maintain eye wash fountain and quick-drench facilities in
work area.
Skin Protection: Wear impervious gloves, apron, and/or clothing.
Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators: Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Use a NIOSH or
European Standard EN 149 approved respirator when necessary.
Ventilation System: A system of local and/or general exhaust is recommended to keep employee exposures below the Airborne
Exposure Limits. Local exhaust ventilation is generally preferred because it can control the emissions of the contaminant at its
source, preventing dispersion of it into the general work area. Please refer to the ACGIH document, "Industrial Ventilation, A
Manual of Recommended Practices", most recent edition, for details.
SECTION 9: PHYSICAL AND CHEMICAL PROPERTIES
Appearance: Clear, colorless liquid Boiling Point: 56.17C (133.1F)
Odor: Characteristic, acetone-like Melting Point: -94.2C (-137.6F)
Solubility: Miscible in water Vapor Density: 2.0 (Air=1)
Specific Gravity: 0.79 (Water = 1) Vapor Pressure (mm Hg): 190 @ 20C (68F)
pH: Not available. Evaporation Rate: 7.7 (Butyl Acetate = 1)
Molecular Formula: C3H6O % Volatiles by Volume: 100
Molecular Weight: 58.09
SECTION 10: STABILITY AND REACTIVITY DATA
Stability: Stable at room temperature in sealed containers.
Hazardous Decomposition Products: Carbon dioxide and carbon monoxide may form when heated to decomposition.
Hazardous Polymerization: Will not occur.
Incompatibilities: Highly reactive with oxidizing agents, acids, alkalis, and chlorine compounds.
Conditions to Avoid: Incompatible materials, ignition sources, and excess heat.
MSDS# 1002-009 Revision 0 Effective Date 04/11/02 Page 2 of 4
SECTION 11: TOXICOLOGICAL INFORMATION
RTECS#: AL3150000 for CAS# 67-64-1:
LD50/LC50:
Oral, rat: LD50 = 5800 mg/kg Inhalation, rat: LC50 = 50100 mg/m3 8/H
Oral, mouse: LD50 = 3000 mg/kg
Carcinogenicity: Not listed by ACGIH, IARC, NIOSH, NTP, or OSHA.
Toxicity to Reproductive System: Tests on laboratory animals for reproductive effects are cited in Registry of Toxic Effects on
Chemical Substances (RTECS).
Mutagenicity: Tests on laboratory animals for mutagenic effects are cited in Registry of Toxic Effects of Chemical Substances
(RTECS).
SECTION 12: ECOLOGICAL INFORMATION
Environmental Fate: When released into the soil, this material is expected to readily biodegrade. When released into the soil, this
material is expected to leach into groundwater. When released into the soil, this material is expected to quickly evaporate. When
released into water, this material is expected to readily biodegrade. When released to water, this material is expected to quickly
evaporate. This material is not expected to significantly bioaccumulate. When released into the air, this material may be moderately
degraded by reaction with photochemically produced hydroxyl radicals. When released into the air, this material may be
moderately degraded by photolysis. When released into the air, this material is expected to be readily removed from the
atmosphere by wet deposition.
Environmental Toxicity: This material is not expected to be toxic to aquatic life. The LC50/96-hour values for fish are over 100
mg/l
SECTION 13: DISPOSAL GUIDELINES
Dispose in compliance with federal, state, and local regulations. Chemical waste generators must determine whether a discarded
chemical is classified as a hazardous waste. US EPA guidelines for the classification determination are listed in 40 CFR Parts
261.3. Additionally, waste generators must consult state and local hazardous waste regulations to ensure complete and accurate
classification.
USEPA RCRA waste numbers U002 and D001.
The information offered here is for the product as shipped. Use and/or alterations to the product such as mixing with other
materials may significantly change the characteristics of the material and alter the RCRA classification and the proper disposal
method.
SECTION 14: TRANSPORT INFORMATION
Ship in accordance with all applicable local, State, Federal, and International transportation regulations.
The following is a summary only. Check regulations for complete information:
United States (Land, D.O.T.) International (Air, I.C.A.O.)
Proper Shipping Name: Acetone Proper Shipping Name: Acetone
Hazard Class: 3 Hazard Class: 3
UN/NA: UN1090 UN/NA: UN1090
Packing Group: II Packing Group: II
MSDS# 1002-009 Revision 0 Effective Date 04/11/02 Page 3 of 4
SECTION 15: REGULATORY INFORMATION
US Federal
TSCA: CAS# 67-64-1 is listed on the TSCA inventory.
OSHA: None of the chemicals in this product are considered highly hazardous by OSHA.
SARA 311/312: Acute: Yes Chronic: Yes Fire: Yes Pressure: No Reactivity: No
US State
CAS# 67-64-1 can be found on the following state right to know lists: California, New Jersey, Florida, Pennsylvania, Minnesota,
Massachusetts.
California Proposition 65: Not regulated.
Other Regulations
EC Hazard Symbol: F 鈥? Highly Flammable
EC Risk and Safety Phrases:
Risk Phrases:
R 11 Highly flammable
Safety Phrases:
S 9 Keep container in a well-ventilated place
S 16 Keep away from sources of ignition - No smoking.
S 23 Do not breathe vapor
. S 33Take precautionary measures against static discharges.
Australian Hazchem Code: 2[Y]E
SECTION 16: OTHER INFORMATION
NOTE: Unless otherwise noted, the information above pertains only to the Acetone solvent in the ampoule/vial.
This MSDS was prepared in accordance with ANSI Z400.1-1993 and 91/155/EEC recommended formats.
The information contained herein is believed to be accurate, but does not purport to be all-inclusive and shall be used only as a
guide. Varian, Inc., does not guarantee said information is accurate or complete, nor shall any of this information constitute a
warranty, whether expressed or implied, as to the safety of the goods, the merchantability of the goods, or the fitness of the goods
for a particular purpose. It is the user鈥檚 responsibility to determine the suitability of this information and to assure the adoption of
necessary precautions. Varian, Inc. shall not be held liable for any damage resulting from handling or from contact with the above
product, nor for the results obtained, or for incidental or consequential damage arising from the use of these data. No freedom from
infringement of any patent, copyright or trademark is to be inferred.
MSDS# 1002-009 Revision 0 Effective Date 04/11/02 Page 4 of 4
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