MSDS 鈥? Epitope Retrieval Solution pH 6 (x10 Concentrate) 500ml
Material Safety Data Sheet
Date updated: 15/2/05
Version: rev-
1. PRODUCT AND COMPANY INFORMATION
Identification of the product
Product name: Epitope Retrieval Solution pH 6 (x10 Concentrate) 500ml
Catalogue code: RE7114
Intended use: Immunohistochemistry
Manufacturer / supplier identification
Company: Novocastra Laboratories Ltd.
Balliol Business Park West
Benton Lane
Newcastle upon Tyne
NE12 8EW, UK.
Telephone: 0044 (0) 191 215 0567
Fax: 0044 (0) 191 215 1152
2. COMPOSITION / INFORMATION ON INGREDIENTS
Component CAS# Percent Classification:
Composition Indications of Danger / R Phrases
Citric Acid 5949-29-1 2.1 % Xi R 36/37/38 41
Sodium hydroxide 1310-73-2 1.0 % C R 35
For indications of danger and R-phrases see Section 16.
3. HAZARDS IDENTIFICATION
Irritant: Irritating to eyes and skin.
For additional information on toxicity, please refer to section 11.
4. FIRST AID MEASURES
Ingestion: If swallowed, induce vomiting immediately as directed by medical personnel. Wash out
mouth with water provided person is conscious. Call a physician.
Inhalation: If inhaled, remove to fresh air. If breathing is difficult, give oxygen.
Skin: Immediately remove contaminated clothing and shoes. In case of skin contact, flush
with plenty of water for at least 15 minutes. Seek medical attention.
Eye: In case of contact with eyes, flush with plenty of water for at least 15 minutes. Assure
adequate flushing by separating the eyelids with fingers. Seek medical advice
immediately.
5. FIRE FIGHTING MEASURES
Autoignition Temp: N/A
Firefighting Protective
Equipment: Wear self-contained breathing apparatus and protective clothing to prevent contact with
skin and eyes.
Specific Hazard(s): Emits toxic fumes under fire conditions.
MSDS RE7114 rev- 10/12/04
MSDS 鈥? Epitope Retrieval Solution pH 6 (x10 Concentrate) 500ml
6. ACCIDENTAL RELEASE MEASURES
Procedure(s) of Personal Precaution(s)
Wear enclosed footwear and chemical-resistant gloves.
Methods for Cleaning Up
Absorb on sand or vermiculite and place in closed containers for disposal. When spilled, the floor may be
slippery. Wipe up the spillage completely. Ventilate area and wash spill site after material pickup is complete.
7. HANDLING AND STORAGE
Handling: Do not breathe vapor. Avoid contact with eyes, skin and clothing. Avoid prolonged or
repeated exposure.
Storage: Keep tightly closed. Store at 2-8潞C.
8. EXPOSURE CONTROLS / PERSONAL PROTECTION
Engineering Controls: Safety shower and eye bath.
Hand Protection: Compatible chemical-resistant gloves.
Eye Protection: Chemical safety goggles.
General Hygiene: Wash contaminated clothing before reuse. Wash thoroughly after handling. Discard
contaminated shoes.
9. PHYSICAL AND CHEMICAL PROPERTIES
Physical Appearance: Liquid Relative Density: No data
Color: Colorless pH: 6
Odor: No data Flash Point: No data
Flammability: No data Solubility: No data
10. STABILITY AND REACTIVITY
Stability: Stable.
Conditions to Avoid: No data.
Materials to Avoid: Strong oxidizing agents.
Hazardous Decomposition
Products: Nature of decomposition products not known.
11. TOXICOLOGICAL INFORMATION
Skin Contact: May cause skin irritation.
Skin Absorption: May be harmful if absorbed through the skin.
Eye Contact: May cause eye irritation.
Inhalation: May be harmful if inhaled.
Ingestion: May be harmful if swallowed.
Signs and Symptoms of Exposure
To the best of our knowledge, the chemical, physical and toxicological properties have not been thoroughly
investigated.
Conditions Aggravated by Exposure
No data.
Chronic Exposure Carcinogen
No data.
12. ECOLOGICAL INFORMATION
No data available.
MSDS RE7114 rev- 10/12/04
MSDS 鈥? Epitope Retrieval Solution pH 6 (x10 Concentrate) 500ml
13. DISPOSAL CONSIDERATIONS
Chemical residues are generally classified as special waste, and as such are covered by regulations which vary
according to location. Contact your local waste disposal authority for advice, or pass to a chemical disposal
company. Rinse out empty containers thoroughly before disposal.
14. TRANSPORTATION INFORMATION
Complete
Shipping Name: No data.
15. REGULATORY INFORMATION
Indication of Danger: Irritant
Irritating to eyes and skin.
S-phrases: S 26 36/37/39 63/64
In case of contact with eyes, rinse immediately with plenty of water and seek medical
advice. Wear suitable protective clothing, gloves, and eye/face protection. In case of
inhalation, remove casualty to fresh air. If swallowed, rinse mouth with water (only if
the person is conscious).
EEC-No.: No data available
Local regulations: No data available
16. OTHER INFORMATION
Indications of danger: C Corrosive
Xi Irritant
Risk Statements: R 35 36/37/38 41
Causes severe burns. Irritating to eyes, respiratory system and skin. Risk of serious
damage to eyes.
The information contained in this Material Safety Data Sheet is believed to be accurate but it is the responsibility
of the user or supplier to determine the applicability of the data to the formulation of necessary safety
precautions. Novocastra Laboratories Ltd. shall not be held responsible for any damage resulting from the use
of the above product or the information contained in this Material Safety Data Sheet.
MSDS RE7114 rev- 10/12/04
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