MATERIAL SAFETY DATA SHEET
Pramitol 5PS Herbicide, EPA Reg. No. 66222-23
Page 1 of 6
1. IDENTIFICATION
Product name: Pramitol 5PS Herbicide
Prometon (5%): 2,4-bis(isopropylamino)-6-methoxy-s-triazine (CAS
Chemical name of active ingredient(s):
#1610-18-0)
Simazine (0.76%): 6-Chloro-N,N鈥?-diethyl-1,3,5-triazine-2,4-diamine
(CAS #122-34-9)
Sodium Chlorate (39.8%)(CAS #7775-09-9)
Sodium Metaborate (40.0%)(CAS #1303-96-4)
Chemical Class: Prometon: Triazine Herbicide
Simazine: Triazine Herbicide
Sodium Chlorate: Herbicide
Sodium Metaborate: Inorganic salt
Manufacturer/Registrant: Makhteshim-Agan of North America
551 Fifth Avenue, Suite 1100
New York, NY 10176
Phone: 212-661-9800
For fire, spill, and/or leak emergencies, Phone: 800-535-5053
contact Infotrac:
For medical emergencies and health and Phone: 877-250-9291
safety inquiries, contact Product Safety
Resources:
2. COMPOSITION/INFORMATION ON INGREDIENTS
OSHA ACGIH NTP/IARC/OSHA
Material Other
PEL TLV Carcinogen
Prometon (5%) N/E N/E N/E No
Simazine (0.76%) N/E N/E N/E No
10 mg/m3 (total
Sodium Chlorate (39.8%) N/E N/E No
dust)*
Sodium Metaborate (40%) 10 mg/m3 5mg/m3 N/E No
N/E=Not Established
*recommended by manufacturer
3. HAZARDS IDENTIFICATION
Notes to Physician
鈥? There is no specific antidote if product is ingested.
鈥? Give a saline laxative and supportive therapy.
鈥? Monitor blood for evidence of hemodialysis and methemoglobinemia.
鈥? Hemodialysis may be required to remove sodium chlorate.
鈥? Barbiturates may be used to control convulsions.
鈥? Treat symptomatically.
鈥? Contact with eyes may require specialized ophthalmologic attention.
鈥? An aqueous suspension of activated charcoal can be administered to absorb remaining toxicant.
鈥? Do not induce emesis.
Symptoms of Acute Exposure
Exposure may cause substantial but temporary eye irritation. If swallowed, mucous membranes may be
damaged, resulting in breathing difficulty, abdominal pain, nausea, vomiting, gastritis, weakness, or
diarrhea. Ingestion of a large amount can lead to cyanosis and hematuria (blood in the urine).
Hazardous Decomposition Products
Reaction of sodium chlorate with acids releases chlorine and chlorine dioxide vapors which may ignite or
explode spontaneously.
Revised 8-4-00
MATERIAL SAFETY DATA SHEET
Pramitol 5PS Herbicide, EPA Reg. No. 66222-23
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Physical Properties
Appearance: White Pellets
Odor: Odorless
Unusual Fire, Explosion and Reactivity Hazards
An active ingredient of this product can react with other materials to cause fire or explosive mixtures. In
this formulation the active ingredients are neutralized.
4. FIRST AID
鈥?
IF SWALLOWED: Call a poison control center or doctor immediately for treatment advice.
鈥?
Have person sip a glass of water if able to swallow.
鈥?
Do not induce vomiting unless told to do so by a poison control center or doctor.
鈥?
Do not give anything by mouth to an unconscious person.
鈥?
IF IN EYES: Hold eye open and rinse slowly and gently with water for 15-20 minutes.
鈥?
Remove contact lenses, if present, after the first 5 minutes, then continue rinsing eye.
鈥?
Call a poison control center or doctor for treatment advice.
鈥?
IF ON SKIN OR Take off contaminated clothing.
鈥?
CLOTHING: Rinse skin immediately with plenty of water for 15-20 minutes.
鈥?
Call a poison control center or doctor for treatment advice.
鈥?
IF INHALED: Move person to fresh air.
鈥?
If person is not breathing, call 911 or an ambulance, then give artificial respiration,
preferably mouth-to-mouth if possible.
鈥? Call a poison control center or doctor for further treatment advice.
Have the product container or label with you when calling a poison control center or doctor or going for
treatment.
NOTES TO PHYSICIAN:
鈥? Probable mucosal damage may contraindicate the use of gastric lavage. Treat for circulatory shock,
respiratory depression, and convulsions, if needed.
鈥? There is no specific antidote if product is ingested.
鈥? Give a saline laxative and supportive therapy.
鈥? Monitor blood for evidence of hemodialysis and methemoglobinemia.
鈥? Hemodialysis may be required to remove sodium chlorate.
鈥? Barbiturates may be used to control convulsions.
鈥? Contact with eyes may require specialized ophthalmologic attention.
鈥? An aqueous suspension of activated charcoal can be administered to absorb remaining toxicant.
鈥? Do not induce emesis.
Medical Condition(s) Likely to be Aggravated By Exposure
None known.
5. FIRE FIGHTING MEASURES
FLASH POINT: Not Applicable
FLAMMABLE LIMITS (%in Air):
LFL: %, UFL: % Not Applicable
AUTOIGNITION TEMPERATURE: Not Available
FLAMMABILITY: Not Flammable
EXTINGUISHING MEDIA: Use dry chemical, foam, or CO2
UNUSUAL FIRE, EXPLOSION AND REACTIVITY HAZARDS: An active ingredient of this product can react with
other materials to cause fire or explosive mixtures. In this formulation the active ingredients are neutralized.
FIRE-FIGHTING EQUIPMENT: Wear full protective clothing and self-contained breathing apparatus. Evacuate
nonessential personnel from the area to prevent human exposure to fire, smoke, fumes, or products of
combustion. Prevent use of contaminated buildings, area and equipment until decontaminated.
6. ACCIDENTAL RELEASE MEASURES
Revised 8-4-00
MATERIAL SAFETY DATA SHEET
Pramitol 5PS Herbicide, EPA Reg. No. 66222-23
Page 3 of 6
ACTION TO TAKE FOR SPILLS/LEAKS: Wear chemical goggles or a full-face shield, rubber gloves, rubber
boots, long-sleeved shirt, long pants, head covering, and use a particulate filter, NIOSH approved per 42 CFR
Part 84. Select N or R or P type as appropriate for the oil characteristics of any other air contaminants present.
Filter efficiency may range from 95-99.97% as appropriate for the size distribution of dusts present. For small
spills, sweep up , keeping dust to a minimum, and place in an approved chemical container. Wash the spill area
with water containing a strong detergent, absorb with pet litter or other absorbent material, sweep up and place in
a chemical container. Seal the container and handle in an approved manner. Flush the area with water to
remove any residue. Do not allow wash water to contaminate water supplies.
7. HANDLING AND STORAGE
Store material in a well-ventilated, secure area out of the reach of children and domestic animals. Do not store
food, beverages or tobacco products in the storage area. Prevent eating, drinking, tobacco usage, and cosmetic
application in areas where there is a potential for exposure to the material. Always wash thoroughly after
handling.
8. EXPOSURE CONTROLS/PERSONAL PROTECTION
RECOMMENDATIONS FOR MANUFACTURING, COMMERCIAL BLENDING, AND PACKAGING WORKERS:
INGESTION: Prevent eating, drinking, tobacco usage, and cosmetic application in areas where there is a
potential for exposure to the material. Always wash thoroughly after handling.
EYE PROTECTION: To avoid eye contact, wear chemical goggles or full-face shield.
SKIN PROTECTION: To avoid skin contact, wear rubber gloves, rubber boots, long-sleeved shirt, long pants and
a head covering.
RESPIRATORY PROTECTION: To avoid breathing dust, use a particulate filter, NIOSH approved per 42 CFR
Part 84. Select N or R or P type as appropriate for the oil characteristics of any other air contaminants present.
Filter efficiency may range from 95-99.97% as appropriate for the size distribution of dusts present.
APPLICATORS AND ALL OTHER HANDLERS: Please refer to the product label for personal protective clothing
and equipment.
9. PHYSICAL AND CHEMICAL PROPERTIES
BOILING POINT: Not Applicable
MELTING POINT: 89-91掳C
VAPOR PRESSURE:
Prometon: 3.10E-06 mbar @ 20掳C
Simazine: 2.94E-03 mPA @ 25掳C
Sodium Chlorate: Not Applicable
Sodium Metaborate: Not Available
SOLUBILITY IN WATER:
Prometon: 0.7 g/L @ 22掳C
Simazine: 6.2 mg/l @ 22掳C
Sodium Chlorate: 49.5% @ 20掳C
Sodium Metaborate: 5.8% @ 20掳C
SPECIFIC GRAVITY/DENSITY: 56.60 lbs./cu.ft.
pH: 10 (1% solution in water) @ 25掳C
APPEARANCE: White Pellets
ODOR: Odorless
10. STABILITY AND REACTIVITY
STABILITY: Stable
CONDITIONS TO AVOID: Combustibles, Heat, Acids, Organic Compounds, Phosphorous, Sulfur, Sulphides,
Ammonium Compounds, and Powdered Metals.
HAZARDOUS DECOMPOSITION PRODUCTS: Reaction of sodium chlorate with acids releases chlorine and
chlorine dioxide vapors which may ignite or explode spontaneously.
HAZARDOUS POLYMERIZATION: Will not occur.
Revised 8-4-00
MATERIAL SAFETY DATA SHEET
Pramitol 5PS Herbicide, EPA Reg. No. 66222-23
Page 4 of 6
11. TOXICOLOGICAL INFORMATION
Acute Toxicity/Irritation Studies
Ingestion: slightly toxic
Oral LD 50 (Rat) 3,396 mg/kg body weight
Dermal: slightly toxic
Dermal LD 50 (Rabbit) >2,020 mg/kg body weight
Inhalation: Slightly toxic
Inhalation LC50 (Rat) >3.727 mg/l air-4 hours
Eye Contact: mildly irritating ( Rabbit)
Skin Contact: non-irritating (Rabbit)
Skin Sensitization: Not a sensitizer (Guinea Pig)
Mutagenic Potential
Prometon: None observed
Simazine: None observed:
Sodium Chlorate: Mutational effects in bacteria and insects
Sodium Metaborate: None observed
Reproductive Hazard Potential
Prometon: None observed
Simazine: None observed
Sodium Chlorate: None observed
Sodium Metaborate: Decreased sperm production and testicular atrophy (males)
Developmental effects and weight loss (fetus)
Chronic/Subchronic Toxicity Studies
Prometon: Liver effects (mice)
Simazine: Decreased survival at high doses (rats)
Sodium Chlorate Effects in the blood (hemolysis) and kidneys (hematuria,
albuminuria, anuria). Ingestion of small amounts may cause weight
loss and loss of appetite.
Sodium Metaborate: None observed
Carcinogenic Potential
Prometon: None observed
Simazine: Increased incidence of mammary tumors (female Sprague-Dawley
rats) sex and species specific effect.
Sodium Chlorate: None observed
Sodium Metaborate: None observed
Other Toxicity Information
Not Available
Toxicity of Other Components
Target Organs
Active Ingredients:
Prometon: Liver
Simazine: Mammary Gland
Sodium Chlorate: Blood and Kidneys
Sodium Metaborate: Testes
Inert Ingredients Not Available
12. ECOLOGICAL INFORMATION
Summary of Effects
Prometon: Practically nontoxic to birds and slightly toxic to aquatic invertebrates and fish.
Simazine: Practically nontoxic to birds and aquatic invertebrates. Slightly toxic to fish.
Sodium Chlorate: Not Available.
Sodium Metaborate: Harmful to boron sensitive plants in high quantities.
Revised 8-4-00
MATERIAL SAFETY DATA SHEET
Pramitol 5PS Herbicide, EPA Reg. No. 66222-23
Page 5 of 6
Eco-Acute Toxicity
Prometon: Rainbow Trout 96-hour LC50 19.6 mg/L
Bluegill Sunfish 96-hour LC50 41.5 mg/L
Daphnia magna 48-hour LC50 37.5 mg/L
Bobwhite Oral LD50 >2,264 mg/kg
Mallard Oral LD50 3,158 mg/kg
Bobwhite 8-day Dietary LC50 >5,620 ppm
Mallard 8-day Dietary LC50 >5,620 ppm
Simazine: Rainbow Trout 96-hour LC50 70.5 mg/L
Bluegill Sunfish 96-hour LC50 16 mg/L
Daphnia magna 48-hour LC50 >100 mg/L
Mallard Oral LD50 >4,640 mg/kg
Bobwhite 8-day Dietary LC50 >20,000 ppm
Mallard 8-day Dietary LC50 >10,000 ppm
Sodium Chlorate: Not Available
Sodium Metaborate: Rainbow Trout 24-day LC50 150 mg B/L
Eco-Chronic Toxicity
Prometon: Fish (Fathead minnow) Early Life Stage MATC 13.7 mg/L
Invertebrate (Daphnia magna) Life Cycle MATC 4.83 mg/L
Mallard Reproduction NOEC 50 ppm
Bobwhite Reproduction NOEC 175 ppm
Simazine: Invertebrate (Daphnia magna) Life Cycle MATC 0.07 mg/L
Mallard Reproduction NOEC 150 ppm
Bobwhite Reproduction NOEC 100 ppm
Sodium Chlorate: Not Available
Sodium Metaborate: Not Available
Environmental Fate
Prometon: Not Available
Simazine: Not Available
Sodium Chlorate: Not Available
Sodium Metaborate: Naturally occurring and ubiquitous in the environment
13. DISPOSAL CONSIDERATIONS
DISPOSAL METHOD: Do not reuse product containers. Dispose of product containers, waste containers, and
residues according to local, state, and federal health and environmental regulations.
Characteristic Waste: Not Applicable
Listed Waste: Not Applicable
14. TRANSPORT INFORMATION
DOT Classification: Not Applicable; No label or Placard Required
B/L Freight Classification: Compound; Tree or Weed Killing (Herbicide), Dry, N.O.I.B.N.
International Transportation: Not Applicable
15. REGULATORY INFORMATION
SARA Title III Classification
Section 311/312: Acute Health Hazard
Chronic Health Hazard
Section 313 Chemical(s) Simazine (0.76%) (CAS No. 122-34-9)
Proposition 65
Not Application
CERCLA Reportable Quantity
None
RCRA Classification
Not Applicable
Revised 8-4-00
MATERIAL SAFETY DATA SHEET
Pramitol 5PS Herbicide, EPA Reg. No. 66222-23
Page 6 of 6
TSCA Status
Exempt from TSCA
16. OTHER INFORMATION:
NFPA Hazard Ratings
Health: 2 0 Least
Flammability: 0 1 Slight
Reactivity: 0 2 Moderate
3 High
4 Severe
Revised Date: 8-4-00; Supercedes 2-14-00 and 8/7/98
This MSDS is applicable to all product produced after February 14, 2000.
The information and recommendations herein are based upon data believed to be correct. However, no
guarantee or warranty of any kind, expressed or implied, is made with respect to the information contained herein.
For additional information about this product, contact Makhteshim-Agan of North America, 551 Fifth Avenue, Suite
1100, New York, NY 10176, (212) 661-9800
Revised 8-4-00
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