SECTION V HEALTH HAZARD DATA
MATERIAL SAFETY DATA SHEET CC 380
Threshold Limited Value
ALDON None established (ACGIH 1992-93). Highly toxic: 0.02 grams may be fatal.
1533 W.Henrietta Rd. No LD50 oral-rat data is available.
CC 380
Avon, New York 14414 MSDS No.
庐
CORPORATION March 25, 1996
Effective Date
(716) 226-6177
Effects of Overexposure
INGESTION: May be fatal if swallowed. Avoid breathing dust. Irritating to
SECTION I NAME 24 HOUR EMERGENCY ASSISTANCE skin and eyes. Nausea, vomiting, diarrhea, abdominal cramps may occur.
Product COLCHICINE
CHEMTREC
3
Health
800-424-9300
Chemical
Emergency and
Colchicine Alkaloid INGESTION: If swallowed, if conscious, give one or two glasses of water to
Synonyms 1
Fire
Day 716-226-6177 drink. Induce vomiting. Repeat until vomit fluid is clear. Call physician
First Aid Procedures
Formula C22H25NO6 immediately. Never give anything by mouth to an unconscious person. SKIN:
0
Reactivity
NFPA Flush thoroughly with water, then wash with mild soap and water. EYES:
HAZARD RATING HMIS *
Unit Size up to 30 grams Flush thoroughly with water for at least 15 minutes, lifting upper and lower
LEAST SLIGHT MODERATE HIGH EXTREME
eyelids occasionally. Get immediate medical attention. INHALATION:
0 1 2 3 4
C.A.S. No. 64-86-8 Remove to fresh air. If not breathing, give artificial respiration. If breathing is
SECTION II INGREDIENTS OF MIXTURES difficult, give oxygen. Get medical attention.
SECTION VI REACTIVITY DATA
Principal Component(s) % TLV Units
Conditions to Avoid
Stability Unstable
Colchicine 100% None established. Excessive temperature and heat.
Stable X
Incompatibility
Strong oxidizers.
(Materials to Avoid)
DANGER! POISON MAY BE FATAL IF
Hazardous
INHALED, SWALLOWED OR ABSORBED THROUGH SKIN. Thermal decomposition or burning may liberate oxides of nitrogen.
Decomposition Products
SECTION III PHYSICAL DATA
Conditions to Avoid
Hazardous Polymerization
Specific Gravity (H2O = 1)
Melting Point (掳F) 142掳-150掳C (287掳-302掳F) No data available.
May Occur Will Not Occur Not applicable.
Percent Volatile
Boiling Point (掳F) No data available. Negligible as solid.
by Volume (%) X
Evaporation Rate
SECTION VII SPILL OR LEAK PROCEDURES
Vapor Pressure (mm Hg) Negligible as solid. Not applicable.
=1)
(
Steps to be taken in case
Vapor Density (Air=1) Negligible as solid.
Wearing proper protective clothing and with good ventilation,
material is released or spilled
recover for use if not contaminated or carefully, without
Solubility in Water Soluble.
making dust, sweep up and place in a suitable container.
Appearance & Odor White to pale yellow powder; no odor
Discharge, treatment, or disposal may be subject to Federal, State or Local laws.
Waste Disposal Method
SECTION IV FIRE AND EXPLOSION HAZARD DATA These disposal guidelines are intended for the disposal of catalog-size quantities only.
Lower
Flammable Limits in Air Upper
Flash Point
Dispose of in an approved incinerator or contract with a licensed waste
% by Volume
(Method Used) Not applicable. NA -------- --------
disposal service.
Extinguisher
SECTION VIII SPECIAL PROTECTION INFORMATION
Carbon dioxide (CO2); dry chemical (ABC); foam.
Media
In the laboratory use good ventilation or work in ventilation hood. If dusty condition
Respiration Protection
(Specify Type) prevail wear a NIOSH/MSHA-approved dust mask or respirator.
SPECIAL FIREFIGHTING
Recommended. No.
Local Exhaust Special
PROCEDURES Ventilation Mechanical (General) Recommended. No.
Other
Protective Gloves Rubber, if needed. May not Eye Protection
In fire conditions, wear a NIOSH/MSHA-approved, self-contained Chemical safety glasses.
be needed in normal handling.
breathing apparatus and protective clothing.
Other Protective
Goggles, smock, apron, ventilation hood, proper gloves, eye wash station.
Equipment
SECTION IX SPECIAL PRECAUTIONS
Precautions to be Taken
UNUSUAL FIRE AND Store in a cool, dry place. Darkens on exposure to light.
in Handling & Storing
EXPLOSION HAZARDS Wash thoroughly after handling.
Keep container tightly closed when not in use.
Read label on container before using. Do not wear contact lenses when working with chemicals.
Other Precautions
Fire or excessive heat may produce hazardous decomposition products;
can react vigorously with oxidizing materials. Avoid breathing dust. Use with adequate ventilation.
Remove and wash contaminated clothing.
For laboratory use only. Not for drug, food or household use. Keep out of reach of children.
Chemical Safety
Approved
Revision Date
No. 4 3/25/96 Michael Raszeja MR
Coordinator
D.O.T. NON-REGULATED. The information contained herein is furnished without warranty of any kind. Employers should use this information only as a supplement to other information
gathered by them and must make independent determinations of suitability and completeness of information from all sources to assure proper use of these
Approved by U.S. Department of Labor "essentially similar" to form OSHA-20 materials and the safety and health of employees. * Hazardous Materials Industrial Standards. Printed on recycled paper.
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