Material Safety Data Sheet
Revision: 5/26/2004
Hazard information is provided for compliance with both the UK Chemicals
(Hazard Information and Packaging) (CHIP) Regulations and the US Hazard
Communication Standard (HCS)
IDENTIFICATION OF THE PRODUCT NAME: PRODUCT CODE: EEC NUMBER:
SUBSTANCE/PREPARATION DL-Ethionine 15640 200-647-0
AND COMPANY
SUPPLIER: Emergency Contact:
USB Corporation, 26111 Miles Road, Cleveland, Ohio 44128 Phone: (216) 765-5000 Chemtrec (800) 424-9300
Outside USA & Canada 703 527 3887
COMPOSITION/
HAZARDOUS COMPONENTS HAZARD CAS NO. %WT TLV CHIP R & S Phrases
DL-Ethionine 67-21-0 100% --- R:40 Limited evidence of a
carcinogenic effect.
R:36/37/38 Irritating to eyes,
respiratory system and skin.
S:24/25 Avoid contact with skin
and eyes.
S:36/37 Wear suitable protective
clothing and gloves.
HAZARDS IDENTIFICATION CHIP
Harmful, Carcinogen Category 3
HCS
Irritant, Suspected Carcinogen
FIRST-AID MEASURES EYES: Flush with water for 15 minutes. Seek medical advice if irritation persists.
SKIN: Flush with water, then wash thoroughly with soap and water. Remove contaminated clothing and
wash before reuse. Seek medical attention if irritation persists.
INHALATION: Remove the victim from exposure and move to fresh air. If breathing is difficult, give
oxygen. If not breathing, give artificial respiration. Keep victim quiet and warm. Seek immediate
medical attention.
INGESTION: Drink water and seek immediate medical attention. Avoid alcoholic beverages. Never give
anything by mouth to an unconscious person.
FIRE-FIGHTING INFORMATION Use media suitable to extinguish the supporting or surrounding fire. Wear NIOSH (or equivalent) approved self
contained breathing apparatus. For small fires only: use carbon dioxide, dry powder or foam. Emits toxic fumes
under fire conditions.
Flash Point = No data available.
ACCIDENTAL RELEASE MEASURES Wear appropriate personal protective equipment and clothing including lab coat, safety goggles, gloves and
NIOSH-approved respirator. Collect in a manner that does not create dust and place in a suitable waste
container. Avoid contact of material with skin or eyes. Use adequate ventilation.
HANDLING AND STORAGE Wear appropriate personal protective equipment and clothing including lab coat, safety goggles, gloves and
NIOSH-approved respirator. Avoid contact of material with skin or eyes. Use adequate ventilation. Store in a
cool, dry, well-ventilated area away from incompatible substances. Keep container tightly closed.
This data sheet is based upon information believed to be reliable. The Company makes no statement or warranty as to the accuracy or completeness of the information
contained herein which is offered for your consideration, investigation and verification. Any use of the information contained in this data sheet must be determined by the user
to be in accordance with appropriate applicable regulations.
For Further Asia Pacific Canada Former Soviet Union Japan Norway Spain USA
Information, +852 2811 8693 1 800 463 5800 +7 (095) 232 0250 81 3 5331 9337 63 89 23 10 935 944 950 USB Corporation
contact your (216) 765-5000
local USB If purchased from
Australia Central and East Europe France Latin America Portugal Sweden
Authorized +61 2 9894 5188 +43 1 982 3826 0169 18 28 00 +55 11 3667 5700 01 417 70 35 018 164000 Amersham Biosciences
distributor, use 1 800 526 3593
Amersham Austria Denmark Germany Middle East and Africa South East Asia Switzerland
Biosciences 01 576 0616 10 +45 4516 2400 07 61 49 03 0 +30 (1) 96 00 687 60 3 724 2080 01 802 81 50
Belgium Finland Italy Netherlands South East Europe UK
0800 73888 358 (9) 512 3940 02 27322 1 0165 580 410 +43 (1) 982 3826 0800 515313
MSDS information may be continued on back of page.
PERSONAL PROTECTION Wear appropriate personal protective equipment and clothing including lab coat, safety goggles, gloves and
NIOSH-approved respirator. A qualified industrial hygienist should evaluate the need for respiratory protection.
Use respiratory protection approved by NIOSH (or equivalent) and appropriate to the hazard. Avoid contact of
material with skin or eyes. Mechanical ventilation or local exhaust as needed to control exposure to dust,
vapors or mists. Access to a safety shower and eye-wash.
PHYSICAL AND CHEMICAL Appearance: White, crystalline flakes Boiling Point: No data available
PROPERTIES Vapor Pressure: No data available Vapor Density: No data available
Solubility (Water): No data available Specific Gravity: No data available
Percent Volatile: No data available Evaporation Rate: No data available
Chemical formula: C6-H13-N-O2-S
STABILITY AND REACTIVITY Product is stable under normal conditions. Incompatible with strong oxidizing agents. Hazardous decomposition
products may include oxides of nitrogen, carbon and sulfur. Hazardous polymerization will not occur.
TOXICOLOGICAL INFORMATION EFFECTS OF OVEREXPOSURE:
To the best of our knowledge the chemical, physical and toxicological properties for this material have not been
thoroughly investigated.
EYES: Contact may cause irritation and slight corneal injury.
SKIN: Contact may cause irritation, dermatitis and/or allergic reaction.
INHALATION: Excessive dust may cause irritation if inhaled and possibly lead to symptoms described under
ingestion.
INGESTION: May cause gastrointestinal irritation with nausea, vomiting and diarrhea.
TARGET ORGAN(S): Liver.
ADDITIONAL INFORMATION:
May cause heritable genetic damage. May cause cancer. May cause adverse reproductive effects based upon
animal studies. Harmful by inhalation, in contact with skin and if swallowed.
Toxicity, tumorigenic, reproductive effects, and mutation data listed in RTECS under RTECS ES6825200.
Oral Rat LDLo = 5 gm/kg (1966). Details of toxic effects not reported other than lethal dose value.
Tumorigenic: carcinogenic by RTECS criteria (1985).
equivocal tumorigenic agent by RTECS criteria (1982).
Carcinogenicity data: EPA GENOTOX PROGRAM 1988, Positive: Carcinogenicity - mouse/rat.
Reproductive: Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number
of implants)(1960). Female fertility index (e.g. # females pregnant per # sperm positive
females; # females pregnant per # females mated), male fertility index (e.g. #
males impregnating females per # males exposed to fertile nonpregnant females (1966).
Paternal Effects - testes, epididymis, sperm duct, spermatogenesis (incl. genetic
material, sperm morphology, motility, and count (1960).
Effects on Embryo or Fetus - fetal death (1962). Fetotoxicity (except death, e.g., stunted
fetus)(1981).
Maternal Effects - parturition (1966).
Effects on Newborn - growth statistics (e.g.%, reduced weight gain), stillbirth (1966).
Definitions: RTECS = Registry of Toxic Effects of Chemical Substances.
EPA = Environmental Protection Agency.
ECOLOGICAL INFORMATION No information available.
DISPOSAL CONSIDERATIONS Dispose of material in accordance with applicable local, state, and federal regulations.
TRANSPORTATION INFORMATION US DOT / IATA: No information available.
REGULATORY INFORMATION RCRA - No applicable information.
SARA 302 - This material does not have an RQ or a TPQ.
SARA 313 - This material is not reportable under Section 313.
EPA TSCA Section 8(b) - Chemical Inventory
8(d) - unpublished health/safety studies.
Exposure Limits - Not established.
California Proposition 65 - No applicable information.
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