Material Safety Data Sheet
Revision: 10/08/2004
Hazard information is provided for compliance with both the UK Chemicals
(Hazard Information and Packaging) (CHIP) Regulations and the US Hazard
Communication Standard (HCS)
IDENTIFICATION OF THE PRODUCT NAME: PRODUCT CODE: EEC NUMBER:
SUBSTANCE/PREPARATION Ouabain, Octahydrate 19833 None
AND COMPANY
SUPPLIER: Emergency Contact:
USB Corporation, 26111 Miles Road, Cleveland, Ohio 44128 Phone: (216) 765-5000 Chemtrec (800) 424-9300
Please visit our website at www.usbweb.com for contact information on USB Outside USA & Canada 703 527 3887
product distributors within your area.
COMPOSITION/
HAZARDOUS COMPONENTS HAZARD CAS NO. %WT TLV CHIP R & S Phrases
Ouabain, Octahydrate 11018-89-6 --- R:23/25 Toxic by inhalation
-99%
and if swallowed.
R:33 Danger of cumulative
effects.
S:45 In case of accident or if
you feel unwell, seek medical
advice immediately (show the
label where possible.
HAZARDS IDENTIFICATION CHIP
Toxic
HCS
Toxic
FIRST-AID MEASURES EYES: Flush with water for 15 minutes. Seek medical advice if irritation persists.
SKIN: Flush with water, then wash thoroughly with soap and water. Remove contaminated clothing and
wash before reuse. Seek medical attention if irritation persists.
INHALATION: Remove the victim from exposure and move to fresh air. If breathing is difficult, give
oxygen. If not breathing, give artificial respiration. Keep victim quiet and warm. Seek immediate
medical attention.
INGESTION: Drink water and seek immediate medical attention. Avoid alcoholic beverages. Never give
anything by mouth to an unconscious person.
FIRE-FIGHTING INFORMATION Use media suitable to extinguish the supporting or surrounding fire. Wear NIOSH (or equivalent) approved self
contained breathing apparatus. For small fires only: use carbon dioxide, dry powder or foam. Emits toxic fumes
under fire conditions.
Flash Point = No data available.
ACCIDENTAL RELEASE MEASURES Wear appropriate personal protective equipment and clothing including lab coat, safety goggles, gloves and
NIOSH-approved respirator. Collect in a manner that does not create dust and place in a suitable waste
container. Avoid contact of material with skin or eyes. Use adequate ventilation.
HANDLING AND STORAGE Wear appropriate personal protective equipment and clothing including lab coat, safety goggles, gloves and
NIOSH-approved respirator. Avoid contact of material with skin or eyes. Use adequate ventilation. Light
sensitive. Store in a cool, dry, well-ventilated area away from incompatible substances. Keep container tightly
closed.
PERSONAL PROTECTION Wear appropriate personal protective equipment and clothing including lab coat, safety goggles, gloves and
NIOSH-approved respirator. A qualified industrial hygienist should evaluate the need for respiratory protection.
Use respiratory protection approved by NIOSH (or equivalent) and appropriate to the hazard. Avoid contact of
material with skin or eyes. Mechanical ventilation or local exhaust as needed to control exposure to dust,
vapors or mists. Access to a safety shower and eye-wash.
PHYSICAL AND CHEMICAL Appearance: Pale yellow crystalline powder Boiling Point: No data available
PROPERTIES Vapor Pressure: No data available Vapor Density: No data available
Solubility (Water): No data available Specific Gravity: No data available
Percent Volatile: No data available Evaporation Rate: No data available
Chemical formula: C29-H44-O12@8H2O Melting Point: -190掳C
MSDS information may be continued on back of page.
STABILITY AND REACTIVITY Product is stable under normal conditions. Incompatible with strong oxidizing agents, strong acids and strong
bases. Light sensitive. May discolor on exposure to light. Hazardous decomposition products may include
carbon oxides. Hazardous polymerization will not occur.
TOXICOLOGICAL INFORMATION EFFECTS OF OVEREXPOSURE:
EYES: Contact may cause irritation and slight corneal injury.
SKIN: May be harmful if absorbed through the skin. Contact may cause irritation and/or allergic reaction.
INHALATION: Toxic if inhaled. May cause irritation to mucous membranes and upper respiratory tract.
INGESTION: Toxic if swallowed. May cause irritation of the gastrointestinal tract with nausea, vomiting and
diarrhea.
TARGET ORGAN(S): Heart.
ADDITIONAL INFORMATION:
May cause liver and kidney damage. May cause methemoglobinemia, which is characterized by chocolate-
brown colored blood, headache, weakness, dizziness, shortness of breath, cyanosis (bluish skin due to deficient
oxygenation of blood), rapid heart rate, unconsciousness and possible death. May cause blood abnormalities.
May cause cardiac effects such as heart blocks, arrhythmias, shock and possible death due to cardiovascular
collapse. Inhalation at high concentrations may cause CNS depression and asphixiation. Danger of cumulative
effects.
Toxicity data listed in RTECS under RN3850000.
LD50 Intraperitoneal Mouse = 1213 ug/kg (1996). Toxic effects may include cardiac arrhythmias (including
changes in conduction).
Definitions: RTECS = Registry of Toxic Effects of Chemical Substances.
ECOLOGICAL INFORMATION No information available.
DISPOSAL CONSIDERATIONS Dispose of material in accordance with applicable local, state, and federal regulations.
TRANSPORTATION INFORMATION US DOT / IATA: Alkaloids, solid, n.o.s (Ouabain), class 6.1, UN1544, PG I, Label: Toxic.
REGULATORY INFORMATION RCRA - No applicable information.
SARA 302 - This material does not have an RQ or a TPQ.
SARA 313 - This material is not reportable under Section 313.
EPA TSCA Section 8(b) - CAS# 11018-89-6 is NOT specifically listed on the TSCA Inventory since it is a
hydrate. This material is considered listed if the CAS# for the anhydrous form
appears on the inventory (40 CFR 720.3 (u)(2)).
Exposure Limits - Not established.
California Proposition 65 - No applicable information.
This data sheet is based upon information believed to be reliable. The Company makes no statement or warranty as to the accuracy or completeness of the
information contained herein which is offered for your consideration, investigation and verification. Any use of the information contained in this data sheet
must be determined by the user to be in accordance with appropriate applicable regulations.
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