MATERIAL SAFETY DATA SHEET
MANUFACTURER Varian Instruments 鈥? Middelburg
ADDRESS Herculesweg 8
4338 PL Middelburg, Netherlands
PHONE 31.118.67100 MSDS Number: 1002-023 Rev. 0
EMERGENCY PHONE 1.800.424.9300 鈥? CHEMTREC USA Date: April 12, 2002
FAX 31.118.633118 Prepared by: Corporate EH&S
SECTION 1: MATERIAL IDENTIFICATION
Product Name: Testmix CP0023
Synonyms: Diaminopropane, Diaminobutane, Diaminopentane, Aminopropanol, Decylamine, Dodecane, Tridecane,
and Tetradecane in Toluene. Toluene is also known as Methylbenzene.
SECTION 2: COMPOSITION
An ampoule/vial containing the following:
Approximate NTP IARC
Component CAS Number Concentration Carcinogen Status Carcinogen Status
Ethylenediamine 107-15-3 0.10% not listed not listed
1,3-Diamino-propane 109-76-2 0.10% not listed not listed
1,4-Diamino-butane 110-60-1 0.10% not listed not listed
1,5-Diamino-pentane 462-94-2 0.10% not listed not listed
1-Amino-2-propanol 78-96-6 0.10% not listed not listed
n-Decylamine 2016-57-1 0.10% not listed not listed
n-Dodecane 112-40-3 0.10% not listed not listed
n-Tridecane 629-50-5 0.10% not listed not listed
n-Tetradecane 629-59-4 0.10% not listed not listed
Toluene 108-88-3 balance not listed not listed
WARNING: This product contains Toluene [CAS# 108-88-3], a chemical known to the State of California to cause birth defects or
other reproductive harm.
NOTE: Unless otherwise noted, the information below pertains only to the Toluene solvent in the ampoule/vial.
SECTION 3: HAZARD IDENTIFICATION
Emergency Overview: Colorless liquid. Flash Point: 5 deg C. May cause central nervous system depression. May cause liver
and kidney damage. This substance has caused adverse reproductive and fetal effects in animals. Causes digestive and
respiratory tract irritation. May cause skin irritation. Aspiration hazard if swallowed. Can enter lungs and cause damage. Harmful or
fatal if swallowed. Causes eye irritation and possible transient injury. Poison! May be absorbed through intact skin. Vapor harmful.
Call physician immediately. Target Organs: Kidneys, central nervous system, and liver.
Potential Health Effects
Inhalation: Inhalation may cause irritation of the upper respiratory tract. Symptoms of overexposure may include fatigue,
confusion, headache, dizziness and drowsiness. Peculiar skin sensations (e. g. pins and needles) or numbness may be produced.
Very high concentrations may cause unconsciousness and death.
Ingestion: Swallowing may cause abdominal spasms and other symptoms that parallel over-exposure from inhalation. Aspiration
of material into the lungs can cause chemical pneumonitis, which may be fatal.
Skin Contact: May cause skin irritation. Prolonged and/or repeated contact may cause irritation and/or dermatitis. May be
absorbed through the skin.
Eye Contact: Causes eye irritation. May result in corneal injury. Vapors may cause eye irritation.
Carcinogen Status: NTP: Not listed IARC: Not listed
MSDS# 1002-023 Revision 0 Effective Date 04/12/02 Page 1 of 4
SECTION 4: FIRST AID INFORMATION
Inhalation: Get medical aid immediately. Remove from exposure to fresh air immediately. If not breathing, give artificial respiration.
If breathing is difficult, give oxygen.
Ingestion: Do NOT induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by
mouth to an unconscious person. Possible aspiration hazard. Get medical aid immediately.
Skin Contact: In case of contact, immediately flush skin with plenty of soap and water for at least 15 minutes. Remove
contaminated clothing and shoes. Wash clothing before reuse. Get medical aid if irritation develops or persists.
Eye Contact: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical
aid. Do NOT allow victim to rub or keep eyes closed.
SECTION 5: FIRE-FIGHTING INFORMATION
Fire: Flash point (closed cup): 5C (40F)
Autoignition temperature: 422C (792F)
Flammable limits in air % by volume: Lower = 1.1 Upper = 19
NFPA Rating: health-2; flammability-3; reactivity-0
Explosion: Above flash point, vapor-air mixtures are explosive within flammable limits noted above. Sealed containers may
rupture when heated. Contact with strong oxidizers may cause fire. Sensitive to static discharge.
Fire Extinguishing Media: Dry chemical, foam or carbon dioxide. Water may be ineffective. Water spray may be used to keep fire
exposed containers cool, dilute spills to nonflammable mixtures, protect personnel attempting to stop leak and disperse vapors.
SECTION 6: ACCIDENTAL RELEASE MEASURES
Use proper personal protective equipment as indicated in Section 8. Ventilate area of leak or spill. Remove all sources of ignition.
Absorb spill with inert material (e.g. vermiculite, sand or earth), scoop up with a nonsparking tool, then place into a suitable
container for disposal. Do not flush to sewer!
SECTION 7: HANDLING AND STORAGE
Handling: Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use only in a well-ventilated
area. Keep container tightly closed. Avoid contact with heat, sparks and flame. Do not get on skin or in eyes. Avoid ingestion and
inhalation.
Storage: Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
SECTION 8: EXPOSURE CONTROL/PERSONAL PROTECTIVE EQUIPMENT
Airborne Exposure Limits: United States - OSHA Permissible Exposure Limit (PEL): 200 ppm (TWA)
United States - ACGIH Threshold Limit Value (TLV): 50 ppm (TWA) (skin)
Australia: Time-weighted average 100 ppm (375 mg/m3), 1993
The Netherlands: MAC-TGG 40 ppm (150 mg/m3), JAN1999
Personal Protective Equipment
Eye Protection: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face
protection regulations in 29 CFR 1910.133 or European Standard EN166. Maintain eye wash fountain and quick-drench facilities in
work area.
Skin Protection: Wear impervious gloves, apron, and/or clothing.
Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators: Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Use a NIOSH or
European Standard EN 149 approved respirator when necessary.
Ventilation System: A system of local and/or general exhaust is recommended to keep employee exposures below the Airborne
Exposure Limits. Local exhaust ventilation is generally preferred because it can control the emissions of the contaminant at its
source, preventing dispersion of it into the general work area. Please refer to the ACGIH document, "Industrial Ventilation, A
Manual of Recommended Practices", most recent edition, for details.
SECTION 9: PHYSICAL AND CHEMICAL PROPERTIES
Appearance: Clear, colorless liquid Boiling Point: 111C (232F)
Odor: Aromatic - benzene-like Melting Point: -95C (-139F)
Solubility: Insoluble Vapor Density: 3.14 (Air=1)
Specific Gravity: 0.9 (Water = 1) Vapor Pressure (mm Hg): 22 @ 20C (68F)
pH: Not available. Evaporation Rate: 2.4 (Butyl Acetate = 1)
Molecular Formula: C7H8 % Volatiles by Volume: 100
Molecular Weight: 92.1
SECTION 10: STABILITY AND REACTIVITY DATA
Stability: Stable at room temperature in sealed containers.
Hazardous Decomposition Products: Carbon dioxide and carbon monoxide may form when heated to decomposition.
MSDS# 1002-023 Revision 0 Effective Date 04/12/02 Page 2 of 4
Hazardous Polymerization: Will not occur.
Incompatibilities: Strong oxidizers, acids, heat, and sources of ignition.
Conditions to Avoid: Incompatibles.
SECTION 11: TOXICOLOGICAL INFORMATION
RTECS#: XS5250000 for CAS# 108-88-3
LD50/LC50:
Oral, rat: LD50 = 636 mg/kg
Inhalation, mouse: LD50 = 400 ppm/24 hour
Carcinogenicity: Not listed by ACGIH, IARC, NIOSH, NTP, or OSHA.
Reproductive effects: Tests on laboratory animals for reproductive effects are cited in Registry of Toxic Effects on Chemical
Substances (RTECS).
Mutagenicity: Tests on laboratory animals for mutagenic effects are cited in Registry of Toxic Effects of Chemical Substances
(RTECS).
SECTION 12: ECOLOGICAL INFORMATION
Environmental Fate: When released into the soil, this material may evaporate to a moderate extent. When released into the
soil, this material is expected to leach into groundwater. When released into the soil, this material may biodegrade to a
moderate extent. When released into water, this material may evaporate to a moderate extent. When released into water, this
material may biodegrade to a moderate extent. When released into the air, this material may be moderately degraded by
reaction with photochemically produced hydroxyl radicals. When released into the air, this material is expected to have a half-
life of less than 1 day. This material is not expected to significantly bioaccumulate.
Environmental Toxicity: This material is expected to be toxic to aquatic life. The LC50/96-hour values for fish are between 10
and 100 mg/l.
SECTION 13: DISPOSAL GUIDELINES
Dispose in compliance with federal, state, and local regulations. Chemical waste generators must determine whether a discarded
chemical is classified as a hazardous waste. US EPA guidelines for the classification determination are listed in 40 CFR Parts
261.3. Additionally, waste generators must consult state and local hazardous waste regulations to ensure complete and accurate
classification.
USEPA RCRA waste numbers: D001 and U220.
The information offered here is for the product as shipped. Use and/or alterations to the product such as mixing with other
materials may significantly change the characteristics of the material and alter the RCRA classification and the proper disposal
method.
SECTION 14: TRANSPORT INFORMATION
Ship in accordance with all applicable local, State, Federal, and International transportation regulations.
The following is a summary only. Check regulations for complete information:
United States (Land, D.O.T.) International (Air, I.C.A.O.)
Proper Shipping Name: Toluene Proper Shipping Name: Toluene
Hazard Class: 3 Hazard Class: 3
UN/NA: : UN1294 UN/NA: UN1294
Packing Group: II Packing Group: II
MSDS# 1002-023 Revision 0 Effective Date 04/12/02 Page 3 of 4
SECTION 15: REGULATORY INFORMATION
US Federal
TSCA: CAS# 108-88-3 is listed on the TSCA inventory.
OSHA: None of the chemicals in this product are considered highly hazardous by OSHA.
SARA 311/312: Acute: Yes Chronic: Yes Fire: Yes Pressure: No Reactivity: No
US State
CAS# 108-88-3 can be found on the following state right to know lists: New Jersey, Florida, Pennsylvania, Minnesota,
Massachusetts.
California Proposition 65: WARNING: This product contains Toluene [CAS# 108-88-3], a chemical known to the State of California
to cause birth defects or other reproductive harm.
Other Regulations
EC Classification: F 鈥? Highly Flammable, Xn - Harmful
EC Risk and Safety Phrases:
Risk Phrases:
R 11 Highly flammable.
R 20 Harmful by inhalation.
Safety Phrases:
S 16 Keep away from sources of ignition - No smoking.
S25 Avoid contact with eyes.
S 29 Do not empty into drains.
S 33 Take precautionary measures against static discharges.
Australian Hazchem Code: 3[Y]E
SECTION 16: OTHER INFORMATION
NOTE: Unless otherwise noted, the information above pertains only to the Toluene solvent in the ampoule/vial.
This MSDS was prepared in accordance with ANSI Z400.1-1993 and 91/155/EEC recommended formats.
The information contained herein is believed to be accurate, but does not purport to be all-inclusive and shall be used only as a
guide. Varian, Inc., does not guarantee said information is accurate or complete, nor shall any of this information constitute a
warranty, whether expressed or implied, as to the safety of the goods, the merchantability of the goods, or the fitness of the goods
for a particular purpose. It is the user鈥檚 responsibility to determine the suitability of this information and to assure the adoption of
necessary precautions. Varian, Inc. shall not be held liable for any damage resulting from handling or from contact with the above
product, nor for the results obtained, or for incidental or consequential damage arising from the use of these data. No freedom from
infringement of any patent, copyright or trademark is to be inferred.
MSDS# 1002-023 Revision 0 Effective Date 04/12/02 Page 4 of 4
|