*** MATERIAL SAFETY DATA SHEET ***
MSS SOLUTIONS (U006-009)
(PAGE 1)
DATE OF PREP: 03/01/90
Each MSS-Solution is factory preformulated and certified for purity and titre.
This document covers MSS-RED, MSS-BLUE, and MSS-YELLOW.
SUMMARY STATEMENT
This document describes the health hazards of the MSS-Solutions and their components; all
must individually and collectively be considered health hazards although, as is seen in
the survey below, the exposure levels even under extremely adverse circumstances are
extremely low. This survey shows the actual exposure limits en- countered in normal use
during CON-TROL-CURE庐 INK CURE ANALYZER鈩? operations as well as those associated with
accidental breakage of ten ampules at one particular instant within the laboratory
environment. Specifically the document includes pertinent data on tetrabromo-ethane-C14
and trifluorotrichloroethane in MSS-RED and the minor additional amounts (5% and 10%,
respectively) of chloroform which are present in MSS-BLUE and MSS-YELLOW. Less than 1% of
cyclo-pentane is included within each formulation.
RADIOCHEMICAL:
Tetrabromoethane-1,2-C14 (aka Acetylene tetrabromide)
SOLVENTS:
Trifluorotrichloroethane (aka Freon 113, Fluorocarbon 113)
Chloroform (aka Trichloro2ethane, Methyl trichloride)
Cyclopentane (aka Pentamethylene)
MSS-SOLUTION FORMULATIONS:
MSS-Solutions are factory preformulated as follows:
Each sealed-in-glass ampule contains a liquid volume of 0.2 millileters (ml) (200
microliters - ul) of low boiling solvent (MSS-RED: trifluorotrichloroethane; MSS-BLUE:
trifluorotri-chloroethane/chloroform of 19/1 ratio by volume; MSS-YELLOW: as in MSS-BLUE
but of 9/1 ratio) and also tetrabromoethane-C14 at a volume concentration of ca.
100,000/1. Each ampule also contains not more than 1% of cyclopentane.
Prior to use each ampule should be upended a number of times (the contents should be
permitted to flow to the other end thus preventing layering of components, shaking if
necessary).
Rules for User Combining of NSS-Solutions:
Aliquot portions of these MSS-Solutions say be combined (with extreme care for cleanliness
and quantity conditions) to form an intermediate level for screening purposes. Thus 100 ul
aliquots MSS-RED and MSS-BLUE, when mixed thoroughly, form 200 ul of
trifluorotrichloroethane/chloroform of 39/1 ratio.
NOTE: Prior to combining, the individual MSS-Solutions must be thoroughly mixed by
upending and shaking to prevent layering effects due to the high density of
tetrabromoethane.
It is not recommended that total ampule contents be combined with the contents of a second
ampule since the nominal 200 ul quantity in each case is production packaged to be 200 +20
or -20 ul and therefore less reliable volumetrically than pipetted aliquots.
NOTE: WHEN OPERATING UNDER THE 'LICENSE EXEMPT" RULES, UNDER NO CONDITIONS MAY THE TOTAL
AMOUNT OF RADIOCHEMICAL IN ANY SINGLE QUANTITY OF ANY MIXTURE EXCEED THE MAXIMAL ALLOWABLE
USNRC AND/OR 'AGREEMENT STATE' LIMIT OF 100 MICROCURIES OF CARBON-14.
*** MATERIAL SAFETY DATA SHEET ***
MSS SOLUTIONS
(PAGE 2)
DATE OF PREP: 03/01/90
SURVEY OF USE
DESCRIPTION
The amounts of C-14 labeled material (1 microCurie C14 per ampule) are classified under
the EXEMPT status in Nuclear Regulatory Commission and/or 'Agreement State" rules and
regulations: in general, up to 100 microCuries of C-14 within a single ampule may be
possessed and used without a specific license and multiple ampules without limit may be
stored in inventory. However, certain other restrictions may also apply; for example, if a
Company has a specific license from an 'Agreement State' for another application, the
possession and use of otherwise EXEMPT quantities MAY be required under that license or an
extension thereof. Under its USNRC license to distribute EXEMPT quantities of C-14 label
material, ERA Systems, Inc. cannot ship at any one time to a single destination more than
a total of I milliCurie of MSS-Solution ampules in the aggregate. (Cf. 10 CFR 32.19)
RECOMMENDED METHOD OF USE
Ampules of MSS-Solution are designed for use in the CON-TROL-CURE庐 INK CURE ANALYZER only.
The ampule and its contents of completely volatile chemical constituents are neither
knowingly sold nor distributed nor are they authorized for any other purpose by
ERA Systems, Inc. The specific uses of these and other formulations are detailed in the
TECHNICAL MANUAL OF THE CON-TROL-CURE庐 INK CURE ANALYZER or in Application Bulletins or
their equivalent supplied at various times by CON-TROL-CURE庐, Inc. or by U V Process
Supply, Inc.
The contents of each ampule are user deposited onto the ink test specimen in 17 microliter
aliquots using the precision syringe provided. The additional quantity permits minor
evaporation from the opened ampule (always stored within the equipment confines) as well
as small quantities for rinsing the syringe when the MSS-Solution is changed from one
formulation to another. 1989 OSHA guidelines and regulations may require use of finger
cots or rubber gloves during the use of the MSS-Solutions. The exhaust fan at the rear of
the instrument case is designed to run continuously during use except under actual testing
conditions. The fan should be ducted to the outside or to another exhaust mechanism. Under
these conditions with the transparent lid closed less than 1% of the vaporized contents
escape to the laboratory environment.
Radiochemical Limits
The amount of radiochemical in each single 17 ul deposition released to the atmosphere
within the enclosure is shown in the followirtg table: (In these tables 2 E-5 = 0.00002)
AMOUNT OF RADIOCHEMICAL RELEASED PER 17 UL DEPOSITION
ml (gas) uCi C14
Tetrabromoethane-C14 2 E-5 .085
Assuming a laboratory of 4 meters x 5 meters x 6 meters dimensions and 20 air changes per
hour) ten tests per hour (considered the maximum number of tests possible including
analysis and time for sample insertion) released and exhausted to the outside air with an
minimal exhaust efficiency of 99% provides no more than the following airborne
concentration within the laboratory environment:
Actual OSHA Standards
Air (pps) 8 hr workplace Actual*
per hour (pps) uCi/ml air
2 E-9 1 2 E-11
* There are no established minimal standards known to E R A Systems. Inc. for vapor phase
levels of carbon-14 when used in LICENSE EXEMPT quantities. The concentrations shown are
extremely low.
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MSS SOLUTIONS
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DATE OF PREP: 03/01/90
Solvent(s)
The amount of solvent (as gas) in each single deposition released to the atmosphere inside
the enclosure is shown in the following table.
MAXIMUM AMOUNTS OF SOLVENT RELEASED
(per 17 microliters liquid deposition)
ml (gas)
MSS-RED Trifluorotrichloroethane 3.4
MSS-BLUE Trifluorotrichloroethane 3.2
Chloroform 0.3
MSS-YELLOW Triflucrotrichloroethane 3
Chloroform 0.6
NOTE: Only ca. 0.03 m1 of gaseous cyclopentane are released each deposition. Again,
assuming a laboratory of 4 meters x 5 meters x 6 meters dimensions and 20 air changes per
hour, ten tests per hour-- released within the enclosure and with at least 99% exhausted
to the outside air--permits no more than the following airborne concentrations within the
laboratory environment:
Actual ppa 1989
Lab Air OSHA Standards
by volume 8 hr workplace
I hr average TWA (ppm)
Trifluorotrichloroethane 2 E-4 1000 (Z-I-A)
Chloroform 3 E-5 2 do.
Cyclopentane 8 E-7 600 do.
The 1989 OSHA standards (Table Z-1-A) are listed in 29 CFR 1910.
Based on the one hour average concentrations, even if 10 ampules of MSS-YELLOW are
inadvertently broken at one time (1.2 E4 times the normal maximal levels cited above) and
allowed to evaporate into the atmosphere within the above cited laboratory, the OSHA
standards will not be exceeded. However in that event of accidental multiple ampule
breakage and spillage into the open laboratory area, E R A Systems, Inc. recommends
temporary evacuation of the area until the spilled and exposed liquid contents have
evaporated and the airborne concentrations have been reduced to a minimum. This
recommendation is based on the thesis that radiation and/or hazardous solvent exposure
should be kept to a minimum.
WARNING: DESPITE THE VERY SMALL AMOUNTS OF MSS-SOLUTIONS ENCOUNTERED IN USE OF THE CON-
TROL-CURE (R) INK CURE ANALYZER, THE MSS-SOLUTIONS MAY BE HAZARDOUS TO HEALTH WHEN
ABSORBED THROUGH THE SKIN OR WHEN LIQUID OR VAPOR ARE IN DIRECT CONTACT WITH THE EYE
OR WHEN INHALED. BY USNRC (AND/OR AGREEMENT STATE) REGULATIONS, EXEMPT QUANTITIES MAY NOT
BE INCORPORATED INTO PRODUCTS USED FOR HUMAN INGESTION.
*** MATERIAL SAFETY DATA SHEET ***
MSS SOLUTIONS
(PAGE 4)
DATE OF PREP: 03/01/90
SECTION I
DISTRIBUTOR: UV PROCESS SUPPLY
ADDRESS: 1229 W. CORTLAND
CHICAGO, IL 60614-4805
TELEPHONE #: (773) 248-0099
IDENTITY: Each MSS Solution is factory preformulated and certified for purity and
titre. This document covers MSS Red, MSS-Blue and MSS-Yellow.
EMERGENCY MEDICAL PHONE NUMBER: 615-875-3931
SECTION II Hazardous Ingredients/Identity Information
Radiochemical: Listing not required by OSHA due to concentration (Less than 0.01%)
1,1,2,2-Tetrabromoethane-C14 The most restrictive OSHA
CAS # 79-27-6 limits of exposure are
a.k.a Acetylene tetrabromide those shown in the Survey
Molecular formula C2H2Br2 above.
Solvents:
Trifluorotrichloroethane do.
CAS # 76-13-1
a.k.a. Freon 1131, Genesolv D
PCA, TF
Molecular formula C2F3C13
Cyclopentane do.
CAS # 287-92-3
a.k.a. Pentamethylene
Molecular formula C5HIO
Chloroform do.
CAS # 67-66-3
a.k.a. Trichloromethane
Molecular formula CHC13
SECTION III Physical/Chemical Characteristics of Components
Radiochemical:
1,1,2,2-Tetrabromoethane-C14
bp: 243 C with decomp 151 C/54mm
mp: -1 C
d: 2.9639 @ 20/4
Colorless to yellow liquid; pungent odor
Slightly soluble water; soluble most organics
Solvents:
Trifluorotrichloroethane
bp: 47 C
mp: 13 C
d: 1.57
fl p: none
Colorless, volatile liquid
Low solubility water; soluble in most organics
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MSS SOLUTIONS
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DATE OF PREP: 03/01/90
Cyclopentane
bp: 49 C
mp: -94 C
d: 0.75
fl p: 19 F
Colorless, volatile liquid; mild odor Low solubility water; soluble most organics
Flammable
Chloroform
bp: 61 C
mp: -63 C
d: 1.48
F1 p: none
Colorless, volatile liquid; strong, unpleasant odor Somewhat Soluble water; soluble
most organics
SECTION IV Fire and Explosion Hazard Data (Components)
Radiochemical:
Due to the extremely small quantity in each ampule, there is no hazard in this
category.
Solvents:
There is no appreciable fire hazard in trifluorotrichloroethane or chloroform both
of which tend to exclude oxygen and/or air from other combustibles due to their
relatively high vapor densities. Since the % cyclopentane is in solution with the
nonflammable solvent(s) and has a similar boiling point, there is no subject hazard
present.
SECTION V Reactivity Data (Components)
Radiochemical:
Due to the extremely small amounts of radioactive labeled compound) the question of
reactivity is insignificant. Nonpolymerizable.
Solvents:
Due to the very limited amounts of these solvents encountered in routine INK CURE
ANALYZER鈩? operations, the reactivity is of very minor significance.
Trifluorotrichloroethane and chloroform are subject to dehalogenation with very
active metals such as sodium, pota5siumf etc. These materials are not examined using
the INK CURE ANALYZER and therefore are not encountered routinely. Both are capable
of being oxidized to form phosgene or fluorophosgene under adverse conditions.
Cyclopentane is a cyclic, saturated hydrocarbon that is unreactive and will not
polymerize. It will oxidize if burned to carbon dioxide, water, and/or carbon
monoxide.
SECTION VI Health Hazard Data (Components)
Radiochemical:
Tetrabromoethane-C14
Each molecule may have two C14 atoms.
Potential human carcinogen and mutagen.
In significant concentrations is an irritant and narcotic. (Significant
concentrations are not found in INK CURE ANALYZER Operations)
Reported in EPA TSCA Inventory.
*** MATERIAL SAFETY DATA SHEET ***
MSS SOLUTIONS
(PAGE 6)
DATE OF PREP: 03/01/90
Solvents:
Trifluorotrichloroethane
Relatively non-toxic
Reported in EPA TSCA Inventory.
Cyclopentane
Little if any toxicity at low concentration.
Reported in EPA TSCA Inventory.
May be narcotic in high concentrations.
Highly flammable.
Chloroform
Probable human carcinogen.
Reported in EPA TSCA Inventory.
Vapor in higher concentrations irritating to eyes, respiratory tract. Narcotic.
Chronic effects: Damage to liver, kidneys) heart If eye contact, wash eyes copiously
with water.
SECTION VII Precautions for Safe Handling and Use (Test Solution)
Steps to be taken in Case Material is Released or Spilled
See survey of use of material in introduction. If solution is spilled on hands, wash
with soap and water. Avoid unnecessary breathing of material.
Waste disposal method.
Open ampule within the instrument case (fan on and exhausting), pour out into beaker
or Petri dish and permit to evaporate. Close front lid. Leave container for about an
hour to insure complete disappearance of components.
Precautions: See survey.
SECTION VIII Control Measures (Test Solution as a Whole)
No respiratory protection is required in routine use.
Ventilation
Attach duct to the outside for exhausting of MESERAN Solution components.
Protective gloves
Rubber gloves or finger cots are recommended when opening and handling ampules and
contents.
Wear safety glasses at all times in chemical laboratory environment.
MSS Solutions
Use care when scoring and opening ampules since they are packaged with a slight
positive pressure of nitrogen.
The information published in this Material Safety Data Sheet has been compiled from our
experience and data presented in various technical publications. It is the user's
responsibility to determine the suitability of this information for the adoption of
necessary safety precautions. E R A Systems, Inc. reserves the right to revise the
information periodically as new information becomes available. The survey information
given in the introductory portions have been thoroughly researched and examined and
represent to the best of our ability the actual exposure limits encountered when the
CON-TROL-CURE庐 INK CURE ANALYZER is used in accord with the recommendations and statements
of the TECHNICAL MANUAL OF THE CON- TROL-CURE庐 INK CURE ANALYZER.
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