MATERIAL SAFETY DATA SHEET
SECTION 1 - IDENTIFICATION OF PRODUCT AND COMPANY
1-866-531-8896
Pfizer Inc Emergency telephone
24 Hours
Pfizer Animal Health Hours of operation
1-800-366-5288
235 East 42nd Street Telephone
New York, NY 10017
Trade names Clavamox 庐 Drops
Product name Clavamox 庐 Drops
Veterinary antibiotic agent
Therapeutic use
Dry powder packaged in a 15ml bottle
Description
SECTION 2 - COMPOSITION
Ingredient CAS Number Amount
Amoxicillin trihydrate* 61336-70-7 40%
Potassium Clavulanate/Syloid (1:1) Not assigned 23%
Trade Secret Trade Secret 37%
*Hazardous
Note: Ingredient(s) indicated as hazardous have been assessed under standards
for workplace safety.
SECTION 3 - HAZARDS IDENTIFICATION
Signal word WARNING!
Statements of hazard MAY CAUSE SENSITIZATION BY INHALATION AND SKIN
CONTACT.
None known; however, direct contact with any foreign material may cause
Eye effects
eye irritation.
Allergic skin reactions might occur following direct contact with this
Skin effects
material.
Repeated exposure to dust or mist may produce allergic reactions.
Inhalation effects
May cause allergic reaction in penicillin-sensitive individuals.
Ingestion effects
Individuals who are allergic to penicillin antibiotics might exhibit allergic
Known clinical effects
reactions, possibly severe.
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SECTION 3 - HAZARDS IDENTIFICATION ... continued
This document has been prepared in accordance with standards for
NOTE:
workplace safety, which require the inclusion of all known hazards of the
product or its ingredients regardless of the potential risk. The
precautionary statements and warnings included may not apply in all
cases. Your needs may vary depending upon the potential for exposure in
your workplace.
SECTION 4 - FIRST AID MEASURES
Remove contaminated clothing and flush exposed area with water. Obtain
Skin
medical assistance if irritation occurs, which may be delayed.
Eyes Immediately flush eyes with water for at least 15 minutes. If irritation
occurs or persists, get medical attention.
Inhalation Remove to fresh air. If discomfort persists, get medical attention.
In the event of swallowing this material, seek medical advice or consult
Ingestion
the emergency contact listed in section 1.
No specific antidotes known.
Antidote
Ocular symptoms may indicate an allergic reaction. Pulmonary symptoms
Note to physician
may indicate an allergic reaction or asthma. For combustion products,
refer to section number 5. This material is not a corrosive agent. Cases of
overexposure should be treated as an overdosage of penicillin antibiotics.
Refer to the most recent edition of the Physicians' Desk Reference and
regional poison control center.
SECTION 5 - FIRE FIGHTING MEASURES
This material is not expected to support combustion. Toxic or corrosive
General hazard
gases are expected during a fire or heating of this material.
Wear approved positive pressure, self-contained breathing apparatus and
Fire fighting instructions
full protective turn out gear. Move containers from fire area if possible
without increased personal risk. Dike area if possible to contain water for
later disposal.
Use carbon dioxide, dry chemical, or water spray.
Extinguishing media
Expected to be >55掳C
Flash point
Toxic or corrosive gases including oxides of carbon, nitrogen, and sulfur
Hazardous combustion
are expected in fires involving this material.
products
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SECTION 6 - ACCIDENTAL RELEASE MEASURES
Review Sections 3, 8 and 12 before proceeding with clean up.
General
Small spill Sweep spilled material into an approved container for disposal. Clean spill
area thoroughly. Prevent discharge to drains.
Large spill Contain the source of the spill or leak if it is safe to do so. Sweep spilled
material into an approved container for disposal. Clean spill area
thoroughly. Prevent discharge to drains.
SECTION 7 - HANDLING AND STORAGE
General handling Avoid contact with eyes, skin and clothing. Avoid breathing dust.
Avoid prolonged storage at elevated temperatures (greater than room
Storage conditions
temperature, approximately 20 degrees C). Keep in tightly sealed
containers in a well-ventilated area.
SECTION 8 - EXPOSURE CONTROLS/PERSONAL PROTECTION
Good general ventilation should be sufficient to control airborne levels.
Ventilation
Respirators are not required for normal use of this material.
Respiratory protection
Eye protection Not required for the normal use of this material. Wear safety glasses or
goggles if eye contact is possible.
Wear protective clothing with long sleeves to avoid routine skin contact.
Skin protection
Wash hands and arms thoroughly after handling this material. Clean up
spills immediately.
Wear protective gloves to avoid routine skin contact.
Hand protection
SECTION 9 - PHYSICAL AND CHEMICAL PROPERTIES
Dry powder packaged in a 15 ml bottle
Physical form
No data available
Color
Mixture
Molecular weight
Mixture
Molecular formula
Not applicable
pH
Not applicable
Boiling point
No data available
Melting point
No data available
Density
No data available
Vapor pressure
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SECTION 9 - PHYSICAL AND CHEMICAL PROPERTIES ... continued
Components are soluble in water
Water solubility
No data available
Solvent solubility
SECTION 10 - STABILITY AND REACTIVITY
Stable
Reactivity
Direct sunlight, conditions that might generate heat and dispersion as a
Conditions to avoid
dust cloud
None known
Incompatibilities
None expected under normal conditions.
Hazardous
decomposition
products
Not expected to occur
Hazardous
polymerization
SECTION 11 - TOXICOLOGY INFORMATION
Acute toxicity
Compound Type Route Species Dosage
Amoxicillin trihydrate LD 50 Oral Rat >15,000 mg/kg
LD 50 Oral Mouse >25,000 mg/kg
LD 50 Oral Rabbit >12,500 mg/kg
LD 50 Subcutaneous Rat > 8,000 mg/kg
Eye Not determined for this mixture. May cause eye irritation based on
components.
Skin Not determined for this mixture. Irritation might occur based on
components.
Not determined for this mixture. However, allergic reactions might occur
Inhalation
based on effects of amoxicillin.
Not determined for this mixture. The rat oral LD50 is expected to be
Ingestion
greater than 2000 mg/kg based on toxicities of individual components and
concentrations present.
This mixture is not expected to be mutagenic, based on effects of
Mutagenicity
individual components.
Sensitization (allergic skin reaction) may occur, based on effects of
Sensitization
individual components.
Not determined for this mixture.
Subchronic effects
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SECTION 11 - TOXICOLOGY INFORMATION ... continued
Not determined for this mixture.
Chronic effects/
carcinogenicity
Sodium saccharin is categorized as an animal carcinogen according to SB
Carcinogen status
and by NTP. No other components of this mixture are listed as
carcinogens.
Group 2 (Sodium Saccharin)
NTP carcinogen
Not determined for this mixture. Components in this mixture are unlikely
Reproductive effects
to produce reproductive effects in humans at levels encountered
occupationally.
Not determined for this mixture. Components in this mixture are unlikely
Teratogenicity
to produce developmental effects in humans at levels encountered
occupationally.
Allergy to penicillins.
At increased risk from
exposure
This mixture contains a penicillin antibiotic.
Additional information
SECTION 12 - ECOLOGICAL INFORMATION
Penicillins are susceptible to degradation by a number of microorganisms
Environmental overview
found in wastewater treatment plants and the general environment.
Resulting degradation products are readily mineralized by environmental
microorganisms.
SECTION 13 - DISPOSAL INFORMATION
Collect for recycling or recovery, if possible. Observe all local and
Disposal procedure
national regulations when disposing of this material. Dispose of material
on site in a licensed chemical incinerator, if allowed by the incinerator
permit. If no on-site incinerator is available, dispose of material in a
licensed commercial chemical incinerator.
SECTION 14 - TRANSPORTATION INFORMATION
Not regulated for transport under USDOT, EUADR, IATA, or IMDG
General shipping
regulations.
instructions
SECTION 15 - REGULATORY INFORMATION
EU Classification Harmful, Irritant
EU Labelling Irritant; (Xi), Harmful; (Xn)
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SECTION 15 - REGULATORY INFORMATION ... continued
EU Label Pictogram(s)
R42 - May cause sensitisation by inhalation.
Risk phrases
R43 - May cause sensitization by skin contact.
S22 - Do not breathe dust.
Safety phrases
S24 - Avoid contact with skin.
S36/37 - Wear suitable protective clothing and gloves.
This product has been classified in accordance with the hazard criteria of
Canadian WHMIS
the CPR and the MSDS contains all of the information required by the
CPR.
SECTION 16 - OTHER
Disclaimer Pfizer Inc believes that the information contained in this Material
Safety Data Sheet is accurate, and while it is provided in good faith, it
is without a warranty of any kind, expressed or implied.
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