MATERIAL SAFETY DATA SHEET
SECTION 1 - IDENTIFICATION OF PRODUCT AND COMPANY
1-866-531-8896
Pfizer Inc Emergency telephone
24 Hours
Pfizer Animal Health Hours of operation
1-800-366-5288
235 East 42nd Street Telephone
New York, NY 10017
Trade names Dormosedan 庐
Product name Dormosedan 庐
Domosedan
Synonyms
Veterinary sedative
Therapeutic use
White, crystalline powder
Description
SECTION 2 - COMPOSITION
Ingredient CAS Number Amount
Detomidine Hydrochloride* 90038-01-0 55%
Sodium Chloride* 7647-14-5 33%
Methylparaben 99-76-3 6.0%
Water 7732-18-5 ~6.0%
*Hazardous
Note: Ingredient(s) indicated as hazardous have been assessed under standards
for workplace safety.
SECTION 3 - HAZARDS IDENTIFICATION
Signal word WARNING!
Statements of hazard MAY CAUSE ALLERGIC SKIN REACTION.
MAY CAUSE EYE AND SKIN IRRITATION.
May cause eye irritation.
Eye effects
Skin effects May cause skin irritation. May cause allergic skin reaction.
An Occupational Exposure Limit has been established for one or more of
Inhalation effects
the ingredients (see Section 8). See 'Other potential health effects', below.
See 'Other potential health effects', below.
Ingestion effects
Dormosedan is a sedative used in animals. Effects of ingestion or
Other potential health
inhalation may be similar to those observed in animals, including
effects
drowsiness and loss of consciousness.
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SECTION 4 - FIRST AID MEASURES
IN CASE OF ACCIDENTAL INNOCULATION, CONSULT THE
Skin
EMERGENCY CONTACT LISTED IN SECTION 1. In case of direct
skin contact, remove contaminated clothing and flush exposed area with
large amounts of water. Obtain medical assistance.
Eyes Immediately flush eyes with water for at least 15 minutes. If irritation
occurs or persists, get medical attention.
Inhalation Remove to fresh air. If discomfort persists, get medical attention.
In the event of swallowing this material, seek medical attention.
Ingestion
SECTION 5 - FIRE FIGHTING MEASURES
This material is not expected to support combustion. Toxic or corrosive
General hazard
gases are expected during a fire or heating of this material.
Wear approved positive pressure, self-contained breathing apparatus and
Fire fighting instructions
full protective turn out gear. Move containers from fire area if possible
without increased personal risk. Dike area if possible to contain water for
later disposal.
Use carbon dioxide, dry chemical, or water spray.
Extinguishing media
No data available
Flash point
Toxic or corrosive gases including oxides of carbon and nitrogen together
Hazardous combustion
with chlorine and hydrogen chloride are expected in fires involving this
products
material.
SECTION 6 - ACCIDENTAL RELEASE MEASURES
Review Sections 3, 8 and 12 before proceeding with clean up.
General
Sweep spilled material into an approved container for disposal keeping
Small spill
dust generation to a minimum. Clean spill area thoroughly. Prevent
discharge to drains.
Large spill Contain the source of the spill or leak if it is safe to do so. Sweep spilled
material into an approved container for disposal keeping dust generation to
a minimum. Clean spill area thoroughly. Prevent discharge to drains.
SECTION 7 - HANDLING AND STORAGE
General handling Avoid contact with eyes, skin and clothing. Avoid breathing dust.
Avoid prolonged storage at elevated temperatures (greater than room
Storage conditions
temperature, approximately 20 degrees C). Keep in tightly sealed
containers in a well-ventilated area and in the absence of light.
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SECTION 8 - EXPOSURE CONTROLS/PERSONAL PROTECTION
The exposure limit(s) listed for solid components are only relevant if dust
Exposure information
may be generated.
Good general ventilation should be sufficient to control airborne levels.
Ventilation
Respirators are not required for normal use of this material.
Respiratory protection
Wear safety glasses or goggles if eye contact is possible.
Eye protection
Wear protective clothing with long sleeves to avoid skin contact. Wash
Skin protection
hands and arms thoroughly after handling this mixture.
Wear impervious gloves if skin contact is possible.
Hand protection
SECTION 9 - PHYSICAL AND CHEMICAL PROPERTIES
Crystalline powder
Physical form
White
Color
Mixture
Molecular weight
Mixture
Molecular formula
No data available
pH
Not applicable
Boiling point
No data available
Melting point
No data available
Density
No data available
Vapor pressure
Components are soluble in water
Water solubility
No data available
Solvent solubility
SECTION 10 - STABILITY AND REACTIVITY
Stable
Reactivity
None for the normal use of this material
Conditions to avoid
None known
Incompatibilities
None expected under normal conditions.
Hazardous
decomposition
products
Not expected to occur
Hazardous
polymerization
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SECTION 11 - TOXICOLOGY INFORMATION
Acute toxicity
Compound Type Route Species Dosage
Detomidine Hydrochloride LD50 Oral Rat 60 mg/kg
Methylparaben LD50 Oral Mouse >8000 mg/kg
LD50 Oral Rat 2280 mg/kg
Eye Not determined for this mixture. Irritation may occur based on components.
Skin Not determined for this mixture. Irritation may occur based on components.
Not determined for this mixture. However, irritation may occur based on
Inhalation
effects of individual components.
Not determined for this mixture. The estimated oral LD50 is less than
Ingestion
2000 mg/kg in rats based on toxicity of detomidine hydrochloride and
concentration present.
Not determined for this mixture. However, based on the effects of
Mutagenicity
individual components this mixture is not expected to be mutagenic.
Not determined for this mixture.
Subchronic effects
Not determined for this mixture.
Chronic effects/
carcinogenicity
None of the components of this formulation is listed as a carcinogen by
Carcinogen status
IARC, NTP or OSHA.
None known.
At increased risk from
exposure
The active ingredient in this product produces sedation and analgesia.
Additional information
SECTION 12 - ECOLOGICAL INFORMATION
The environmental characteristics of this mixture have not been fully
Environmental overview
evaluated. Releases to the environment should be avoided.
SECTION 13 - DISPOSAL INFORMATION
Disposal procedure Collect for recycling or recovery, if possible. Dispose of material on site
in a licensed chemical incinerator, if allowed by the incinerator license or
permit. If no on-site incinerator is available, dispose of material in a
licensed commercial chemical incinerator.
SECTION 14 - TRANSPORTATION INFORMATION
Not regulated for transport under USDOT, EUADR, IATA, or IMDG
General shipping
regulations.
instructions
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SECTION 15 - REGULATORY INFORMATION
Harmful
EU Classification
EU Labelling Xn
EU Label Pictogram(s)
This product has been classified in accordance with the hazard criteria of
Canadian WHMIS
the CPR and the MSDS contains all of the information required by the
CPR.
SECTION 16 - OTHER
Disclaimer Pfizer Inc believes that the information contained in this Material
Safety Data Sheet is accurate, and while it is provided in good faith, it
is without a warranty of any kind, expressed or implied.
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