MATERIAL SAFETY DATA SHEET
SECTION 1 - IDENTIFICATION OF PRODUCT AND COMPANY
1-866-531-8896
Pfizer Inc Emergency telephone
24 Hours
Pfizer Animal Health Hours of operation
1-800-366-5288
235 East 42nd Street Telephone
New York, NY 10017
Trade names Clavamox 庐 Tablets
Product name Clavamox 庐 Tablets
Veterinary antibiotic agent
Therapeutic use
Amoxicillin tablets supplied in strip packs
Description
SECTION 2 - COMPOSITION
Ingredient CAS Number Amount
Amoxicillin trihydrate* 61336-70-7 53%
Clavulanate Potassium/Avicel (1:1) Not assigned 27%
Trade Secret Trade Secret 20%
*Hazardous
Note: Ingredient(s) indicated as hazardous have been assessed under standards
for workplace safety.
SECTION 3 - HAZARDS IDENTIFICATION
Signal word WARNING!
Statements of hazard MAY CAUSE SENSITIZATION BY INHALATION AND SKIN
CONTACT.
None known; however, direct contact with any foreign material may cause
Eye effects
eye irritation.
Allergic skin reactions might occur following direct contact with this
Skin effects
material.
Inhalation effects Not expected due to physical form. Repeated exposure to dust or mist may
produce allergic reactions.
May cause allergic reaction in penicillin-sensitive individuals.
Ingestion effects
Individuals who are allergic to penicillin antibiotics might exhibit allergic
Known clinical effects
reactions, possibly severe.
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SECTION 3 - HAZARDS IDENTIFICATION ... continued
This document has been prepared in accordance with standards for
NOTE:
workplace safety, which require the inclusion of all known hazards of the
product or its ingredients regardless of the potential risk. The
precautionary statements and warnings included may not apply in all
cases. Your needs may vary depending upon the potential for exposure in
your workplace.
SECTION 4 - FIRST AID MEASURES
Remove contaminated clothing and flush exposed area with water. Obtain
Skin
medical assistance if irritation occurs, which may be delayed.
Eyes Immediately flush eyes with water for at least 15 minutes. If irritation
occurs or persists, get medical attention.
Inhalation Remove to fresh air. If not breathing, give artificial respiration. If
discomfort persists, get medical attention.
Get medical attention immediately.
Ingestion
SECTION 5 - FIRE FIGHTING MEASURES
This material is not expected to support combustion. Toxic or corrosive
General hazard
gases are expected during a fire or heating of this material.
Wear approved positive pressure, self-contained breathing apparatus and
Fire fighting instructions
full protective turn out gear. Move containers from fire area if possible
without increased personal risk. Dike area if possible to contain water for
later disposal.
Use carbon dioxide, dry chemical, or water spray.
Extinguishing media
Expected to be >55掳C
Flash point
Toxic or corrosive gases including oxides of carbon, nitrogen, and sulfur
Hazardous combustion
are expected in fires involving this material.
products
SECTION 6 - ACCIDENTAL RELEASE MEASURES
Review Sections 3, 8 and 12 before proceeding with clean up.
General
Small spill Sweep spilled material into an approved container for disposal. Clean spill
area thoroughly. Prevent discharge to drains.
Large spill Contain the source of the spill or leak if it is safe to do so. Scoop or shovel
spilled material into a labeled container for disposal. Clean spill area
thoroughly. Prevent discharge to drains.
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SECTION 7 - HANDLING AND STORAGE
IF TABLETS OR CAPSULES ARE CRUSHED AND/OR BROKEN,
General handling
AVOID BREATHING DUST AND AVOID CONTACT WITH EYES,
SKIN AND CLOTHING.
Avoid prolonged storage at elevated temperatures (greater than room
Storage conditions
temperature, approximately 20 degrees C). Keep in tightly sealed
containers in a well-ventilated area.
SECTION 8 - EXPOSURE CONTROLS/PERSONAL PROTECTION
Good general ventilation should be sufficient to control airborne levels.
Ventilation
Respirators are not required for normal use of this material.
Respiratory protection
Eye protection Not required under normal conditions of use. Wear safety glasses or
goggles if eye contact is possible.
Wear protective clothing with long sleeves to avoid routine skin contact.
Skin protection
Wash hands and arms thoroughly after handling this material. Clean up
spills immediately.
Wear protective gloves to avoid routine skin contact.
Hand protection
SECTION 9 - PHYSICAL AND CHEMICAL PROPERTIES
Tablet
Physical form
No data available
Color
Mixture
Molecular weight
Mixture
Molecular formula
Not applicable
pH
Not applicable
Boiling point
No data available
Melting point
No data available
Density
No data available
Vapor pressure
Components are soluble in water
Water solubility
No data available
Solvent solubility
SECTION 10 - STABILITY AND REACTIVITY
Stable
Reactivity
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SECTION 10 - STABILITY AND REACTIVITY ... continued
Direct sunlight, conditions that might generate heat and dispersion as a
Conditions to avoid
dust cloud
None known
Incompatibilities
None expected under normal conditions.
Hazardous
decomposition
products
Not expected to occur
Hazardous
polymerization
SECTION 11 - TOXICOLOGY INFORMATION
Acute toxicity
Compound Type Route Species Dosage
Amoxicillin trihydrate LD 50 Oral Rat >15,000 mg/kg
LD 50 Oral Mouse >25,000 mg/kg
LD 50 Oral Rabbit >12,500 mg/kg
LD 50 Subcutaneous Rat > 8,000 mg/kg
Eye Not determined for this mixture. May cause eye irritation based on
components.
Skin Not determined for this mixture. Irritation may occur based on components.
Not determined for this mixture. However, allergic reactions might occur
Inhalation
based on effects of amoxicillin.
Not determined for this mixture. The rat oral LD50 is expected to be
Ingestion
greater than 2000 mg/kg based on toxicities of individual components and
concentrations present.
This mixture is not expected to be mutagenic, based on effects of
Mutagenicity
individual components.
Sensitization (allergic skin reaction) may occur, based on effects of
Sensitization
individual components.
Not determined for this mixture.
Subchronic effects
Not determined for this mixture.
Chronic effects/
carcinogenicity
None of the components of this formulation is listed as a carcinogen by
Carcinogen status
IARC, NTP or OSHA.
Not determined for this mixture. Components in this mixture are unlikely
Reproductive effects
to produce reproductive effects in humans at levels encountered
occupationally.
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SECTION 11 - TOXICOLOGY INFORMATION ... continued
Not determined for this mixture. Components in this mixture are unlikely
Teratogenicity
to produce developmental effects in humans at levels encountered
occupationally.
Allergy to penicillins.
At increased risk from
exposure
This mixture contains material that is a penicillin antibiotic.
Additional information
SECTION 12 - ECOLOGICAL INFORMATION
Penicillins are susceptible to degradation by a number of microorganisms
Environmental overview
found in wastewater treatment plants and the general environment.
Resulting degradation products are readily mineralized by environmental
microorganisms.
SECTION 13 - DISPOSAL INFORMATION
Collect for recycling or recovery, if possible. Observe all local and
Disposal procedure
national regulations when disposing of this material. Dispose of material
on site in a licensed chemical incinerator, if allowed by the incinerator
permit. If no on-site incinerator is available, dispose of material in a
licensed commercial chemical incinerator.
SECTION 14 - TRANSPORTATION INFORMATION
SECTION 15 - REGULATORY INFORMATION
EU Classification Harmful, Irritant
EU Labelling Xn, Xi
EU Label Pictogram(s)
R42 - May cause sensitisation by inhalation.
Risk phrases
R43 - May cause sensitization by skin contact.
S22 - Do not breathe dust.
Safety phrases
S24 - Avoid contact with skin.
S36/37 - Wear suitable protective clothing and gloves.
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SECTION 15 - REGULATORY INFORMATION ... continued
This product has been classified in accordance with the hazard criteria of
Canadian WHMIS
the CPR and the MSDS contains all of the information required by the
CPR.
SECTION 16 - OTHER
Disclaimer Pfizer Inc believes that the information contained in this Material
Safety Data Sheet is accurate, and while it is provided in good faith, it
is without a warranty of any kind, expressed or implied.
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