Pharmacia & Upjohn
PANMYCIN AQUADROPS 庐 Suspension
MATERIAL SAFETY DATA SHEET
Agent ID# 43793
1. CHEMICAL PRODUCT AND 3. HAZARDS IDENTIFICATION
COMPANY IDENTIFICATION
EMERGENCY OVERVIEW: May cause eye and skin
COMMON NAME: PANMYCIN AQUADROPS 庐 irritation and allergic reactions.
Suspension PRIMARY ROUTE(S) OF EXPOSURE: Skin contact,
SYNONYMS: 411521 鈥? EDP Number eye contact, ingestion, and inhalation.
MOLECULAR FORMULA: Mixture EFFECTS OF OVEREXPOSURE: May cause
USE: Veterinary product indicated for oral administration gastrointestinal irritation via oral exposure. May cause
to dogs and cats in the treatment of infections caused by hypersensitivity to tetracyclines.
organisms sensitive to tetracycline hydrochloride. Not for
human use.
MANUFACTURER/SUPPLIER: 4. FIRST AID MEASURES
PHARMACIA & UPJOHN CO., A SUBSIDIARY OF
PHARMACIA CORP.
EYES: Rinse immediately with plenty of water, also under
7171 PORTAGE RD
the eyelids, for at least 15 minutes.
KALAMAZOO, MI 49001-0199
SKIN: Wash off with soap and water. Take off all
TELEPHONE NUMBERS:
contaminated clothing immediately.
(616) 833-5122 - (24 Hours)
INHALATION: Move to fresh air.
(616) 833-7555 - (8:00 AM - 4:30 PM, EST)
INGESTION: Contact a physician or poison control center.
2. COMPOSITION/INFORMATION
5. FIRE FIGHTING MEASURES
ON INGREDIENTS
FLASH POINT: Nonflammable.
INGREDIENT 1
LOWER EXPLOSION LIMIT (LEL): Not applicable.
COMMON NAME: Sucrose
UPPER EXPLOSION LIMIT (UEL): Not applicable.
% BY WEIGHT: 65 %
AUTOIGNITION TEMPERATURE: Not applicable.
CAS NUMBER: 57-50-1
EXTINGUISHING MEDIA: Water, carbon dioxide or dry
EXPOSURE LIMIT(S): OSHA PEL-TWA: (Respirable
fraction): 5 mg/m3 chemical.
OSHA PEL-TWA: (Total dust): 15 mg/m3 FIRE FIGHTING PROCEDURES: Wear self-contained
ALGIH TLV-TWA: 10 mg/m3 breathing apparatus and full-body protective equipment.
UNUSUAL FIRE OR EXPLOSION HAZARDS: None
known.
INGREDIENT 2
HAZARDOUS COMBUSTION PRODUCTS: Carbon
COMMON NAME: Water
monoxide. Carbon dioxide. Nitrogen oxides.
% BY WEIGHT: 23 % (approximately)
CAS NUMBER: 7732-18-5
EXPOSURE LIMIT(S): Not established.
6. ACCIDENTAL RELEASE MEASURES
INGREDIENT 3
COMMON NAME: Tetracycline
STEPS TO BE TAKEN IN CASE MATERIAL IS
% BY WEIGHT: 10 %
RELEASED OR SPILLED: Provide ventilation and
CAS NUMBER: 60-54-8
respiratory, skin and eye protection to prevent over-
Product contains in each milliliter, tetracycline-base
exposure. Keep out of drains; prevent entry to surface
equivalent to 100 mg of tetracycline hydrochloride.
water, groundwater and soil. Vacuum or scoop spilled
EXPOSURE LIMIT(S): PHARMACIA & UPJOHN
material and place in container.
EXPOSURE LIMIT-TWA: 1 mg/m3
INGREDIENT 4 7. HANDLING AND STORAGE
COMMON NAME: Non-hazardous Ingredient(s).
% BY WEIGHT: 2 % (approximately).
EXPOSURE LIMIT(S): Not established. PRECAUTIONS FOR HANDLING AND STORING:
Avoid contact with skin, eyes and clothing. Wash
EXPOSURE LIMIT(S) FOR THE MATERIAL: Not thoroughly after handling. Launder contaminated clothing
established. before reuse. Store in a cool, dry place. Protect from light.
Keep out of reach of children.
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Pharmacia & Upjohn
PANMYCIN AQUADROPS 庐 Suspension
MATERIAL SAFETY DATA SHEET
Agent ID# 43793
8. EXPOSURE CONTROLS/ 12. ECOLOGICAL INFORMATION
PERSONAL PROTECTION
ECOTOXICITY: Static LC50 24 hour (fish - striped bass):
1,818 mg/L (for tetracycline hydrochloride)
RESPIRATORY PROTECTION: Not required.
VENTILATION: Local exhaust.
PROTECTIVE GLOVES: Not required.
13. DISPOSAL CONSIDERATIONS
EYE PROTECTION: Not required.
OTHER PROTECTIVE EQUIPMENT: Not required.
WASTE DISPOSAL METHOD: Dispose of by
9. PHYSICAL AND CHEMICAL incineration in accordance with applicable international,
PROPERTIES national, state and/or local waste disposal regulations.
14. SHIPPING REGULATIONS
APPEARANCE/PHYSICAL STATE: Liquid.
MOLECULAR WEIGHT: Mixture.
SOLUBILITY IN WATER: Soluble.
Not regulated for transportation by the United States
Department of Transportation (DOT), International Mari-
time Organization (IMO), or International Air Transport
10. STABILITY AND REACTIVITY Association (IATA). May be subject to state and/or local
transportation requirements.
STABILITY: Stable at normal conditions.
PHYSICAL CONDITIONS TO AVOID: None. 15. OTHER INFORMATION
INCOMPATIBILITY WITH OTHER MATERIALS:
None.
REVIEWED BY: Environment & Safety
HAZARDOUS DECOMPOSITION PRODUCTS: None.
DISCLAIMER: The information contained in the MSDS is
HAZARDOUS POLYMERIZATION: Does not occur.
believed to be correct as of its date of issuance. BY
MAKING THE MSDS AVAILABLE, PHARMACIA &
11. TOXICOLOGICAL INFORMATION UPJOHN CO. DOES NOT MAKE ANY EXPRESS OR
IMPLIED WARRANTY (INCLUDING ANY
WARRANTY OF MERCHANTABILITY OR FITNESS
ACUTE STUDIES: The following data applies to
FOR A PARTICULAR PURPOSE) REGARDING THE
tetracycline.
MSDS, ITS ACCURACY OR THE PRODUCT TO
MULTIPLE ROUTES TDLo (WOMAN): 310 mg/kg
WHICH IT RELATES. Anyone using this information
INTRAVENOUS LD50 (RAT): 160 mg/kg
agrees that Pharmacia & Upjohn shall not be held liable
ORAL TDLo (HUMAN): (based on its negligence or otherwise) for any personal
WOMAN: 240 mg/kg (32 to 33 weeks pregnant): injury or other damage relating to, or arising from such
teratogenic effects. use, including direct, incidental, or consequential damage
WOMAN: 600 mg/kg/15 days: systemic effects.
and such user agrees to indemnify Pharmacia & Upjohn
ORAL LD50 (RAT): 807 mg/kg
for any claims arising out of its use.
INTRAPERITONEAL LD50 (RAT): 320 mg/kg
OTHER STUDIES:
16. LABELING
GENOTOXICITY: Mutagenicity: Mutagenic potential in
in vitro mammalian cell assays.
TERATOGENICITY: The use of drugs of the tetracycline
This drug is subject to FDA labeling requirements; there-
class during tooth development (last half of pregnancy,
fore, it is exempt from the labeling requirements of the
infancy and childhood to the age of 8 years) may cause
OSHA Hazard Communication Standard.
permanent discoloration of the teeth.
CARCINOGENICITY: Ingredient(s) are not listed as
NDC 0009-0571-02
carcinogenic by IARC, NTP or OSHA.
NDC 0009-0571-06
July 31, 2001
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