**** SECTION 2 - COMPOSITION, INFORMATION ON INGREDIENTS ****
+----------------+--------------------------------------+----------+-----------+
| CAS# | Chemical Name | % | EINECS# |
|----------------|--------------------------------------|----------|-----------|
| 104-94-9 |p-Anisidine | 99.0 | 203-254-2 |
+----------------+--------------------------------------+----------+-----------+
Hazard Symbols: T+ N
Risk Phrases: 26/27/28 33 50
**** SECTION 3 - HAZARDS IDENTIFICATION ****
EMERGENCY OVERVIEW
Very toxic by inhalation, in contact with skin and if swallowed.
Danger of cumulative effects. Very toxic to aquatic organisms.
Potential Health Effects
Eye:
Causes severe eye irritation.
Skin:
May be absorbed through the skin in harmful amounts. May cause skin
sensitization, an allergic reaction, which becomes evident upon
re-exposure to this material. If absorbed, may cause symptoms
similar to those for ingestion. Effects of contact may be delayed.
May cause contact dermatitis.
Ingestion:
May cause irritation of the digestive tract. May cause kidney
damage. May cause methemoglobinemia, cyanosis (bluish discoloration
of skin due to deficient oxygenation of the blood), convulsions, and
death. Methemoglobinemia is characterized by dizziness, drowsiness,
headache, breath shortness, cyanosis with bluish skin, rapid heart
rate and chocolate-brown colored blood. May be harmful if swallowed.
Inhalation:
May cause severe allergic respiratory reaction. May cause
respiratory tract irritation. Effects of inhalation may be delayed.
Chronic:
May cause cancer according to animal studies.
**** SECTION 4 - FIRST AID MEASURES ****
Eyes:
Immediately flush eyes with plenty of water for at least 15 minutes,
occasionally lifting the upper and lower eyelids. Get medical aid
immediately.
Skin:
Flush skin with plenty of soap and water for at least 15 minutes
while removing contaminated clothing and shoes. Wash clothing before
reuse. Get medical aid if symptoms occur.
Ingestion:
If victim is conscious and alert, give 2-4 cupfuls of milk or water.
Get medical aid immediately. Do NOT induce vomiting. If conscious and
alert, rinse mouth and drink 2-4 cupfuls of milk or water.
Inhalation:
Get medical aid immediately. Remove from exposure to fresh air
immediately. If breathing is difficult, give oxygen. If breathing has
ceased apply artificial respiration using oxygen and a suitable
mechanical device such as a bag and a mask.
Notes to Physician:
Antidote:
None reported.
**** SECTION 5 - FIRE FIGHTING MEASURES ****
General Information:
As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full
protective gear. May polymerize explosively when involved in a fire.
Extinguishing Media:
In case of fire, use water, dry chemical, chemical foam, or
alcohol-resistant foam. Do NOT get water inside containers. Cool
containers with flooding quantities of water until well after fire is
out.
**** SECTION 6 - ACCIDENTAL RELEASE MEASURES ****
General Information: Use proper personal protective equipment as indicated
in Section 8.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth),
then place in suitable container. Avoid runoff into storm sewers and
ditches which lead to waterways. Clean up spills immediately,
observing precautions in the Protective Equipment section. Avoid
generating dusty conditions. Provide ventilation.
**** SECTION 7 - HANDLING and STORAGE ****
Handling:
Wash thoroughly after handling. Remove contaminated clothing and
wash before reuse. Use only in a well-ventilated area. Minimize dust
generation and accumulation. Do not get in eyes, on skin, or on
clothing. Do not ingest or inhale.
Storage:
Store in a tightly closed container. Store in a cool, dry,
well-ventilated area away from incompatible substances.
**** SECTION 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION ****
Engineering Controls:
Facilities storing or utilizing this material should be equipped
with an eyewash facility and a safety shower. Use adequate general or
local exhaust ventilation to keep airborne concentrations below the
permissible exposure limits.
Personal Protective Equipment
Eyes:
Wear appropriate protective eyeglasses or chemical
safety goggles as described by OSHA's eye and face
protection regulations in 29 CFR 1910.133 or European
Standard EN166.
Skin:
Wear appropriate protective gloves and clothing to
prevent skin exposure.
Clothing:
Wear appropriate protective clothing to minimize
contact with skin.
Respirators:
Wear a NIOSH/MSHA or European Standard EN 149
approved full-facepiece airline respirator in the
positive pressure mode with emergency escape
provisions. Follow the OSHA respirator regulations
found in 29CFR 1910.134 or European Standard EN 149.
Always use a NIOSH or European Standard EN 149
approved respirator when necessary.
**** SECTION 9 - PHYSICAL AND CHEMICAL PROPERTIES ****
Physical State: Solid
Appearance: beige
Odor: amine-like
pH: Not available.
Vapor Pressure: .0006 mm Hg @ 25 C
Viscosity: Not available.
Boiling Point: 240 - 243 deg C @ 760.00mm Hg
Freezing/Melting Point: 58 deg C
Autoignition Temperature: 515 deg C ( 959.00 deg F)
Flash Point: 122 deg C ( 251.60 deg F)
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature: >300 deg C
Solubility in water: Soluble in hot water.
Specific Gravity/Density: 1.0700g/cm3
Molecular Formula: C7H9NO
Molecular Weight: 123.15
**** SECTION 10 - STABILITY AND REACTIVITY ****
Chemical Stability:
Stable under normal temperatures and pressures.
Conditions to Avoid:
Incompatible materials, dust generation.
Incompatibilities with Other Materials:
Strong oxidizing agents, acids, acid chlorides, acid anhydrides,
chloroformates.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, carbon dioxide, nitrogen.
Hazardous Polymerization: May occur.
**** SECTION 11 - TOXICOLOGICAL INFORMATION ****
RTECS#:
CAS# 104-94-9: BZ5450000
LD50/LC50:
CAS# 104-94-9: Oral, mouse: LD50 = 1410 mg/kg; Oral, rabbit: LD50 =
2900 mg/kg; Oral, rat: LD50 = 1320 mg/kg; Skin, rat: LD50 = 3200
mg/kg.
Carcinogenicity:
p-Anisidine -
ACGIH: A4 - Not Classifiable as a Human Carcinogen
IARC: Group 3 carcinogen
See actual entry in RTECS for complete information.
**** SECTION 12 - ECOLOGICAL INFORMATION ****
Ecotoxicity:
Water flea EC50 = 0.18 mg/L; 48 Hr.; UnspecifiedBacteria:
Phytobacterium phosphoreum: EC50 = 14.5 mg/L; 30 Minutes; Microtox
test, 15 degrees C
**** SECTION 13 - DISPOSAL CONSIDERATIONS ****
Dispose of in a manner consistent with federal, state, and local regulations.
**** SECTION 14 - TRANSPORT INFORMATION ****
IATA
Shipping Name: ANISIDINES, SOLID
Hazard Class: 6.1
UN Number: 2431
Packing Group: III
IMO
Shipping Name: ortho-ANISIDINE
Hazard Class: 6.1
UN Number: 2431
Packing Group: III
RID/ADR
Shipping Name: ANISIDINES, SOLID
Dangerous Goods Code: 6.1(12C)
UN Number: 2431
**** SECTION 15 - REGULATORY INFORMATION ****
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: T+ N
Risk Phrases:
R 26/27/28 Very toxic by inhalation, in contact with
skin and if swallowed.
R 33 Danger of cumulative effects.
R 50 Very toxic to aquatic organisms.
Safety Phrases:
S 28 After contact with skin, wash immediately
with...
S 36/37 Wear suitable protective clothing and
gloves.
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
S 61 Avoid release to the environment. Refer to
special instructions/Safety data sheets.
WGK (Water Danger/Protection)
CAS# 104-94-9: 2
United Kingdom Occupational Exposure Limits
CAS# 104-94-9: OES-United Kingdom, TWA 0.1 ppm TWA; 0.51 mg/m3 TWA
Canada
CAS# 104-94-9 is listed on Canada's DSL List.
CAS# 104-94-9 is listed on Canada's Ingredient Disclosure List.
Exposure Limits
CAS# 104-94-9: OEL-AUSTRALIA:TWA 0.1 ppm (0.5 mg/m3);Skin
OEL-AUSTRIA:TWA 0.1 ppm (0.5 mg/m3);Skin
OEL-BELGIUM:TWA 0.1 ppm (0.5 mg/m3);Skin
OEL-DENMARK:TWA 0.1 ppm (0.5 mg/m3);Skin
OEL-FINLAND:TWA 0.5 mg/m3;STEL 1.5 mg/m3;Skin;CAR
OEL-FRANCE:TWA 0.1 ppm (0.5 mg/m3);Skin;Carcinoge
OEL-GERMANY:TWA 0.1 ppm (0.5 mg/m3);Skin
OEL-INDIA:TWA 0.1 ppm (0.5 mg/m3);Skin
OEL-THE NETHERLANDS:TWA 0.1 ppm (0.5 mg/m3);Skin
OEL-THE PHILIPPINES:TWA 0.5 mg/m3;Skin
OEL-RUSSIA:STEL 1 mg/m3;Skin
OEL-SWITZERLAND:TWA 0.1 ppm (0.5 mg/m3);STEL 0.2 ppm;Skin
OEL-UNITED KINGDOM:TWA 0.1 ppm (0.5 mg/m3);Skin
OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV
OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGI TLV
US FEDERAL
TSCA
CAS# 104-94-9 is listed on the TSCA inventory.
**** SECTION 16 - ADDITIONAL INFORMATION ****
MSDS Creation Date: 5/05/1999 Revision #2 Date: 8/02/2000
The information above is believed to be accurate and represents the best
information currently available to us. However, we make no warranty of
merchantability or any other warranty, express or implied, with respect to
such information, and we assume no liability resulting from its use. Users
should make their own investigations to determine the suitability of the
information for their particular purposes. In no way shall the company be
liable for any claims, losses, or damages of any third party or for lost
profits or any special, indirect, incidental, consequential or exemplary
damages, howsoever arising, even if the company has been advised of
the possibility of such damages.
--------------------------------------------------------------------------------
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|
|
|
| ALL MSDS PAGES IN THIS GROUP
| | NAME | CAS |
|
8-Hydroxyjulolidine
| 41175-50-2 |
|
(R)-2-Hydroxybutyl p-tosylate, 98+%
| 103745-07-9 |
|
TETRACHLOROETHYLENE DENSITY STANDARD
| 127-18-4 |
|
Tetrachloroethylene, 98% (GC)
| 127-18-4 |
|
Tetraethylammonium Bromide, 98%
| 71-91-0 |
|
Tetrahydrofuran, P.A., Stabilized with 0.025% BHT
| 109-99-9 |
|
Tetrahydrofuran, anhydrous, 99.9% Packaged under nitrogen. Stabilized
| 109-99-9 |
|
Tetrahydrofuran, 99.5+%, spectrophotometric grade
| 109-99-9 |
|
Unpreserved Tetrahydrofuran
| 109-99-9 |
|
Tetrahydroxy-P-Quinone Monohydrate, 99% (Titr.)
| 319-89-1 |
|
Ethyl L-Lactate,95% (GC)
| 687-47-8 |
|
N,N'-Dicyclohexylcarbodiimide, 99%
| 538-75-0 |
|
Tetramethylammonium hydroxide pentahydrate , 97% (48-52 wt% tma-oh)
| 10424-65-4 |
|
Tetramethylammonium hydroxide, 10% in water
| 75-59-2 |
|
Triphenyl phosphate
| 115-86-6 |
|
Benzamide, 99%
| 55-21-0 |
|
Thiosalicylic Acid, 98%
| 147-93-3 |
|
4-Iodobenzoic acid, 98%
| 619-58-9 |
|
Thiamine Hydrochloride, 98.5-101.5% (on the Anhydrous Substance)
| 67-03-8 |
|
Mercaptoacetic Acid, 98%
| 68-11-1 |
|
Mercaptoacetic acid
| 68-11-1 |
|
P-Anisidine, 99%
| 104-94-9 |
|
Thiourea, 99%
| 62-56-6 |
|
Thiourea, Reagent ACS, 99+% (Titr.)
| 62-56-6 |
|
Sebacoyl Chloride, Tech. 90-95% Active Chlorine
| 111-19-3 |
|
Quinaldine, 97%
| 91-63-4 |
|
Toluene, 99%
| 108-88-3 |
|
Toluene, Scintillation Grade
| 108-88-3 |
|
Tetrapropylammonium Chloride, 94% (Titr.)
| 5810-42-4 |
|
Toluene, Reagent ACS, Spectro Grade, 99.5% (GC)
| 108-88-3 |
|
Toluene, Reagent ACS
| 108-88-3 |
|
Toluene for HPLC
| 108-88-3 |
|
Himic anhydride, 99%
| 826-62-0 |
|
Tributyl Phosphate, 99%
| 126-73-8 |
|
Tributylamine, 99%
| 102-82-9 |
|
4-Picoline, 98%
| 108-89-4 |
|
Trichloroethylene, 99+% (Stabilized)
| 79-01-6 |
|
Titanium Rod 6.35mm Diam. 99.97%
| 7440-32-6 |
|
3-Amino-1H-1,2,4-triazole
| 61-82-5 |
|
Alizarin Complexone Dihydrate, Indicator Grade
| 3952-78-1 |
|
Phenylphosphate, disodium salt dihydrate, 98%
| 3279-54-7 |
|
Toluene-d8, 99+ atom % D
| 2037-26-5 |
|
Toluene-d8, packaged in 0.50 ml ampules, 100.0 atom % D
| 2037-26-5 |
|
Farnesol, mixture of isomers, 96%
| 4602-84-0 |
|
2,4-Dihydroxybenzaldehyde, 98%
| 95-01-2 |
|
tris-(Hydroxymethyl)-aminomethane, 99+%
| 77-86-1 |
|
Tris(hydroxymethyl)aminomethane, reagent acs
| 77-86-1 |
|
Hexyl alcohol
| 111-27-3 |
|
Sodium phosphate, tribasic dodecahydrate, p.a.
| 7601-54-9 |
|
4-Nitro-1,2-Phenylenediamine, 98%
| 99-56-9 |
|
|