**** SECTION 2 - COMPOSITION, INFORMATION ON INGREDIENTS ****
+----------------+--------------------------------------+----------+-----------+
| CAS# | Chemical Name | % | EINECS# |
|----------------|--------------------------------------|----------|-----------|
| 389-08-2 |Nalidixic acid | >98% | 206-864-7 |
+----------------+--------------------------------------+----------+-----------+
Hazard Symbols: XN
Risk Phrases: 22 40
**** SECTION 3 - HAZARDS IDENTIFICATION ****
EMERGENCY OVERVIEW
Harmful if swallowed. Limited evidence of a carcinogenic effect.
Potential Health Effects
Eye:
May cause painful sensitization to light. May cause visual
abnormalities including: blurring, abnormal color vision, loss of
sight.
Skin:
May cause skin irritation. May cause skin sensitization, an allergic
reaction, which becomes evident upon re-exposure to this material.
Ingestion:
May cause central nervous system depression, characterized by
excitement, followed by headache, dizziness, drowsiness, and nausea.
Advanced stages may cause collapse, unconsciousness, coma and
possible death due to respiratory failure.
Inhalation:
May cause effects similar to those described for ingestion.
Chronic:
Prolonged or repeated exposure may cause adverse reproductive
effects.
**** SECTION 4 - FIRST AID MEASURES ****
Eyes:
Flush eyes with plenty of water for at least 15 minutes,
occasionally lifting the upper and lower eyelids. Immediately flush
eyes with plenty of water for at least 15 minutes, occasionally
lifting the upper and lower eyelids. Get medical aid.
Skin:
Flush skin with plenty of water for at least 15 minutes while
removing contaminated clothing and shoes. Immediately flush skin
with plenty of water for at least 15 minutes while removing
contaminated clothing and shoes. Get medical aid if irritation
develops or persists.
Ingestion:
Get medical aid immediately. Do NOT induce vomiting. If conscious
and alert, rinse mouth and drink 2-4 cupfuls of milk or water. Wash
mouth out with water.
Inhalation:
Remove from exposure and move to fresh air immediately. If not
breathing, give artificial respiration. If breathing is difficult,
give oxygen. Get medical aid.
Notes to Physician:
**** SECTION 5 - FIRE FIGHTING MEASURES ****
General Information:
As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full
protective gear. During a fire, irritating and highly toxic gases
may be generated by thermal decomposition or combustion.
Extinguishing Media:
In case of fire, use water, dry chemical, chemical foam, or
alcohol-resistant foam. Use foam, dry chemical, or carbon dioxide.
**** SECTION 6 - ACCIDENTAL RELEASE MEASURES ****
General Information: Use proper personal protective equipment as indicated
in Section 8.
Spills/Leaks:
Wear a self contained breathing apparatus and appropriate personal
protection. (See Exposure Controls, Personal Protection section).
Sweep up, then place into a suitable container for disposal. Avoid
generating dusty conditions.
**** SECTION 7 - HANDLING and STORAGE ****
Handling:
Wash thoroughly after handling. Remove contaminated clothing and
wash before reuse. Use only in a well-ventilated area. Minimize dust
generation and accumulation. Do not get on skin or in eyes. Do not
ingest or inhale.
Storage:
Store in a tightly closed container. Store in a cool, dry,
well-ventilated area away from incompatible substances.
**** SECTION 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION ****
Engineering Controls:
Use adequate general or local exhaust ventilation to keep airborne
concentrations below the permissible exposure limits.
Exposure Limits
CAS# 389-08-2:
Personal Protective Equipment
Eyes:
Wear safety glasses and chemical goggles if splashing
is possible. Wear appropriate protective eyeglasses or
chemical safety goggles as described by OSHA's eye and
face protection regulations in 29 CFR 1910.133 or
European Standard EN166.
Skin:
Wear appropriate protective gloves and clothing to
prevent skin exposure. Wear appropriate gloves to
prevent skin exposure.
Clothing:
Wear appropriate protective clothing to minimize
contact with skin. Wear appropriate protective
clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29
CFR 1910.134 or European Standard EN 149. Use a
NIOSH/MSHA or European Standard EN 149 approved
respirator if exposure limits are exceeded or if
irritation or other symptoms are experienced.
**** SECTION 9 - PHYSICAL AND CHEMICAL PROPERTIES ****
Physical State: Solid
Color: white to yellow
Odor: none reported
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: 437 deg F
Autoignition Temperature: Not available.
Flash Point: Not available.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature: Not available.
Solubility in water: 0.1% @23C in water
Specific Gravity/Density: Not available.
Molecular Formula: C12H12N2O3
Molecular Weight: 232.0956
**** SECTION 10 - STABILITY AND REACTIVITY ****
Chemical Stability:
Stable under normal temperatures and pressures.
Conditions to Avoid:
High temperatures, dust generation.
Incompatibilities with Other Materials:
None reported.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, carbon dioxide, nitrogen.
Hazardous Polymerization: Has not been reported.
**** SECTION 11 - TOXICOLOGICAL INFORMATION ****
RTECS#:
CAS# 389-08-2: QN2885000
LD50/LC50:
CAS# 389-08-2: Oral, mouse: LD50 = 572 mg/kg; Oral, rat: LD50 = 2040
mg/kg.
Carcinogenicity:
Nalidixic acid -
California: carcinogen, initial date 5/15/98
Other:
See actual entry in RTECS for complete information.
**** SECTION 12 - ECOLOGICAL INFORMATION ****
Other
No information available.
**** SECTION 13 - DISPOSAL CONSIDERATIONS ****
Products which are considered hazardous for supply are classified as Special
Waste and the disposal of such chemicals is covered by regulations which may
vary according to location. Contact a specialist disposal company or the local
waste regulator for advice. Empty containers must be decontaminated before
returning for recycling.
**** SECTION 14 - TRANSPORT INFORMATION ****
IATA
Not regulated as a hazardous material.
IMO
Not regulated as a hazardous material.
RID/ADR
Not regulated as a hazardous material.
**** SECTION 15 - REGULATORY INFORMATION ****
European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: XN
Risk Phrases:
R 22 Harmful if swallowed.
R 40 Limited evidence of a carcinogenic effect.
Safety Phrases:
S 36/37/39 Wear suitable protective clothing, gloves
and eye/face protection.
WGK (Water Danger/Protection)
CAS# 389-08-2: 2
Canada
CAS# 389-08-2 is listed on Canada's DSL List.
CAS# 389-08-2 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 389-08-2 is not listed on the TSCA inventory.
It is for research and development use only.
**** SECTION 16 - ADDITIONAL INFORMATION ****
MSDS Creation Date: 9/02/1997 Revision #4 Date: 3/18/2003
The information above is believed to be accurate and represents the best
information currently available to us. However, we make no warranty of
merchantability or any other warranty, express or implied, with respect to
such information, and we assume no liability resulting from its use. Users
should make their own investigations to determine the suitability of the
information for their particular purposes. In no way shall the company be
liable for any claims, losses, or damages of any third party or for lost
profits or any special, indirect, incidental, consequential or exemplary
damages, howsoever arising, even if the company has been advised of
the possibility of such damages.
--------------------------------------------------------------------------------
--------------------------------------------------------------------------------
|
|
|
| ALL MSDS PAGES IN THIS GROUP
| | NAME | CAS |
|
N,N,N'-Triethylethylenediamine, 99+%
| 105-04-4 |
|
Triethanolamine hydroiodide, 99%
| 7601-53-8 |
|
1-Methyl-5-mercaptotetrazole, sodium salt, dihydrate
| 51138-06-8 |
|
3-Octanone, 99%
| 106-68-3 |
|
4-Nitrochalcone, 99%
| 1222-98-6 |
|
Diphenyl-2-Pyridylmethane, 99+%
| 3678-70-4 |
|
3-Dimethylaminobenzoic Acid (Pract)
| 99-64-9 |
|
Ethyl 5-Nitroindole-2-Carboxylate, 95+%
| 16732-57-3 |
|
Fast red pdc salt
| 80-22-8 |
|
Copper(II) Chloride, Anhydrous, 98%
| 7447-39-4 |
|
4-Dimethylaminobenzoic acid, 98%
| 619-84-1 |
|
N,N,N',N'-Tetramethyl-1,3-propanediamine, 99+%
| 110-95-2 |
|
1-Butan(ol-d), 98+ atom % D
| 71-36-3 |
|
4-Heptanol, 99% (GC)
| 589-55-9 |
|
Thymolphthalein, Reagent ACS, 99% (UV-Vis)
| 125-20-2 |
|
Diphenyliodonium bromide
| 1483-73-4 |
|
Methyl formate-d, 98+ atom % d
| 23731-38-6 |
|
m-Nitrobenzoyl chloride
| 121-90-4 |
|
Acetaldehyde ammonia trimer, 98%
| 75-39-8 |
|
P-Amino-L-Phenylalanine Hydrochloride Hemihydrate, 99%
| 24286-13-3 |
|
3-Bromobenzoic Acid , 99%
| 585-76-2 |
|
N,N-Diethyl-p-phenylenediamine oxalate
| 62637-92-7 |
|
D-Gluconic Acid, Calcium Salt, 99%
| 299-28-5 |
|
Bis-Acrylamide
| 110-26-9 |
|
TEMED
| 110-18-9 |
|
N,N,N',N'-Tetramethyl-p-phenylenediamine dihydrochloride
| 637-01-4 |
|
BDCS Silylation Reagent
| 68-12-2 |
|
Nalidixic Acid
| 389-08-2 |
|
1-Nitroso-2-naphthol, 98%
| 131-91-9 |
|
Samarium, 99.9%, -40 Mesh
| 7440-19-9 |
|
Benzine
| 71-43-2 |
|
7-Nitroindole-2-Carboxylic Acid, 90-95% (HPLC)
| 6960-45-8 |
|
Naphthalene
| 91-20-3 |
|
Diphenylphosphoryl azide, 98%
| 26386-88-9 |
|
9,10-Dihydrophenanthrene, 95%
| 776-35-2 |
|
Ammonium Perrhenate(VII), 99.999%
| 13598-65-7 |
|
Methyl-2-Nitrobenzoate, 99%
| 606-27-9 |
|
Mixture of dichlorodimethylsilane and silicon(iv)chloride (86 and
| 75-78-5 |
|
Beta-Bromophenetole, 98%
| 589-10-6 |
|
Tri-n-butyltin hydride, 97%
| 688-73-3 |
|
Ethylene/propylene/diene terpolymer, high molecular weight
| 25038-36-2 |
|
Tetraethylammonium iodide, 98%
| 68-05-3 |
|
(4-Pyridylmethylamino)-acetaldehyde diethylacetal
| 35822-55-0 |
|
Glutathione, Reduced , 98%
| 70-18-8 |
|
Alloxan, Monohydrate
| 2244-11-3 |
|
Nickel Metal
| 7440-02-0 |
|
2-Acetylfluorene, 98%
| 781-73-7 |
|
Nickel (II) Acetate Tetrahydrate
| 6018-89-9 |
|
Gallium(III) perchlorate hydrate, 99%
| |
|
2-Nitrophenyl isocyanate, 99% (GC)
| 3220-86-3 |
|
|