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MSDS Material Safety Data Sheet
CAS

28-32-5
28-45-6

File Name: hycorbiomedical_com---MSDS_048_03-HYTEC_Calibrators.asp
                                                                                                   Page 1 of 5
HYCOR BIOMEDICAL INC.
MATERIAL SAFETY DATA SHEET
1. IDENTIFICATION OF THE SUBSTANCE/PREPARATION AND OF THE COMPANY

Commercial Product ALLERGY REAGENTS - CALIBRATORS

Name : IgE Reference Units, IgG Reference Serum

List Number(s): 70418, 70420, 71214, 71242, 72002, 72003, 73025, 74001, 74006, 74011, 74119, 74122, 74124,
308057, 308058, 308059, 308060, 308061, 308062, 308063, 308064, 308066, 308070, 308071, 308072, 308073,
308078, 308079, 308080, 308083, 308085, 308101, 308177, 308178, 309174, 317178, 318174, 318176, 318177,
322113, 322114, 322115, 322116, 322117, 322118, 325103, 325104, 325105

Product Classification: Component of in vitro diagnostic device

Manufacturer Company: Hycor Biomedical Inc. Distributor: (As appropriate)
7272 Chapman Ave.
Garden Grove, CA 92841 (USA)
Emergency Telephone No.:
USA No. 1-(714)- 933-3000 Attention: Randy Wilson


2. CHEMICAL CHARACTERIZATION/INFORMATION ON INGREDIENTS

Character: Product contains 0.02% Sodium Azide.
Contains human serum. Human serum is tested for the presence of antibodies to Human Immunodeficiency Virus (HIV
1 e 2), as well as for Hepatitis B Surface Antigen (HBsAg) and HCV and found to be negative.
Hazardous substances (chemical): sodium azide
See EEC directive 67/548/EEC and amendments.

Substance %w/w Health Class CAS No. EINECS ANNEX 1
No.
Sodium azide (sodium azoture) 0.095% T+; N R:28-32-50/53 26628-22-8 247-852-1 011-004-00-7
S: (1/2)-28-45-60-61

See section 16 for spelling of R and S phrases.
3. HAZARDS IDENTIFICATION

Classification: Product is chemically classified as not a dangerous preparation
Calibrators contain human serum and are potentially infectious. Handle controls as biohazardous material.




MSDS 048.03 27 Oct 05
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Commercial Product: ALLERGY REAGENTS - CALIBRATORS

4. FIRST AID MEASURES

Ingestion: If swallowed, drink large amount of water; keep patient rested and seek medical advice immediately. Keep
residual liquid and give it to the physician.

Skin Care: Wash vigorously with antiseptic soap and water. In case of injured skin, stimulate bleeding and disinfect with
suitable germicide solution. In case of contact with mucous surfaces, wash with flowing water or saline physiological
solution for at least 15 minutes. Seek medical attention immediately and give the residual liquid to the physician.
Remove contaminated clothing and wash before reuse.
Eyes contact: flush eyes with large amounts of water for 15 minutes. Seek medical attention and give the residual liquid
to the physician.
In any case consult a physician and show the container and / or label.


5. FIRE-FIGHTING MEASURES

Extinguishing Media: water, dry chemical, foam or carbon dioxide. No restriction.
Special Fire Fighting Procedures: In case of fire, wear a respirator.
Unusual Fire Fighting Procedures: Keep away from heat, sparks and flames.
Thermal Decomposition: Dangerous decomposition is not anticipated.

6. ACCIDENTAL RELEASE MEASURES

Steps To Be Taken After Spillage: Wear appropriate personal protective equipment (rubber gloves and protective
clothing) Avoid any direct contact, especially in case of injured skin. Dilute liquids with water and absorb with an inert
material (vermiculite, dry sand, earth) and place in a biohazardous waste container. Wash contaminated area with a
germicide product. Disinfect after handling.

Absorbant Material: Do not use combustible materials, as sawdust.
Waste Disposal Method: Consult a specialist for disposal of the spilled substance.

7. HANDLING AND STORAGE
Handling: Keep in its original container, tightly closed. Protect from physical damage. Open and handle container
carefully. Wear rubber gloves and protective clothing. Do not swallow. Avoid contact with eyes. Avoid prolonged and
excessive contact with skin. Handle as potentially biohazardous material. Avoid contact with injured skin.
Storage: Store between +2掳C (35,6掳F) and +8掳C (46,4掳F).
Other Precautions: Do not store near heat or ignition sources.




MSDS 048.03 27 Oct 05
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Commercial Product: ALLERGY REAGENTS - CALIBRATORS

8. EXPOSURE CONTROLS/PERSONAL PROTECTION

Product TLV: Not known.
Sodium azide TLV (pure substance): 0.29 mg/m3 (Ceiling)
Respiratory Protection: None
Eye Protection: Protective chemical safety goggles, where splashing is possible. Maintain eye wash fountain and quick-
drench facilities in work area.
Hand Protection: One-way gloves. Wash hands before breaks and disinfect them at end of the work.
Other Protective Equipment: Protective Clothing

9. PHYSICAL AND CHEMICAL PROPERTIES
Physical State: liquid Ignition Temperature: N/A

Color: N/A Explosion limits: N/A
Odor: N/A Vapor Pressure: N/A
pH Value: 6-9
Solubility In Water: N/A
Boiling Point: N/A
In: N/A
Melting Point: N/A
Viscosity: N/A
Flash Point: N/A

10. STABILITY AND REACTIVITY
Stable under ordinary conditions of use and storage (2梅8掳C; 35,6梅46,4掳F).

Hazardous Decomposition Products: carbon monoxide, carbon dioxide, nitrogen oxides

Hazardous Polymerization: will not occur.

Incompatibilities: sensitive to heat, strong acids, oxidizing agents, bases and heavy metals
Conditions to avoid: heat-sensitive




MSDS 048.03 27 Oct 05
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Commercial Product: ALLERGY REAGENTS - CALIBRATORS

11. TOXICOLOGICAL INFORMATION
Referred to Sodium azide (in pure form)
Referred to the product:
LD50 Oral: Not known LD50 Oral (rat): 27 mg/kg
LD50 Oral (mouse): 27 mg/kg
LD50 Skin: Not known
LDLO Oral (woman): 14 mg/kg
LDLO Oral (man): 29 mg/kg
LD50 Inhalation: Not known
LC50 Inhalation (rat): 37 mg/m3
LD50 Skin (rat): 50 mg/kg
Irritation, skin: Not known
LD50 Skin (rabbit): 20 mg/kg
LD50 Subcutaneous (rat): 45100 碌g/kg
Irritation, eyes: Not known
LD50 Intravenous (rat): 47500 碌g/kg
IARC category: none
Product Toxicological Information: The toxicological properties have not been determined. May be harmful by ingestion
or prolonged contact with skin. Toxicological properties have not been thoroughly investigated

12. ECOLOGICAL INFORMATION
Use product according with good laboratory practices and avoid to release to the environment.
Ecotoxicity (aquatic toxicity): Product contains 0,095% sodium azide. Sodium azide concentration is below EC directives
allowed limits (0,25%, w/w). So, product is classified as not harmful to the aquatic environment, according to the
legislation in force (1999/45/CE and amendments). However, because sodium azide LC50/96H values for fish are less
than 1 mg/L, do not empty product into water or drains.
Mobility: Product is not expected to selectively partition and adsorb to soil or sediments.
Persistence and Degradability: when released into the soil, or into water, this product is not expected to persist in the
environment.
Bioaccumulative potential: The product is not expected to significantly bioaccumulate.
Other adverse effects: None

13. DISPOSAL CONSIDERATIONS

Observe all Federal, State and Local laws concerning Health and Pollution.

14. TRANSPORT INFORMATION
Transport in accordance with national and international regulations.
Is not subject to current regulations for transportation of hazardous goods (eg. GGUS/ADR, GGUE/RID, IMDG,
IATA/ICAD.
Must be transported at controlled temperature (2梅8 掳C; 36.6梅46.4 掳F). Do not compromise container integrity.


15. REGULATORY INFORMATION
Label information:

Hazard Symbol: none

Indication of danger: none

Risk phrases: none

Safety phrases: none

MSDS 048.03 27 Oct 05
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Commercial Product: ALLERGY REAGENTS - CALIBRATORS

16. OTHER INFORMATION

The information herein is believed to be correct as of the date hereof but is provided without warranty of any kind. The
recipient of our products is responsible for observing any laws and guidelines applicable.
Use the product according with box insert and MSDS information. Please, read well instructions for use and warning.

Legend:
R phrases:
R 28: Very toxic if swallowed
R 32: Contact with acids liberates very toxic gas
R 50/53: Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.

S phrases:
S 1/2:Keep locked up and out of the reach of children
S 28: After contact with skin, wash immediately with plenty of water
S 45: In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible)
S 60: This material and its container must be disposed of as hazardous waste
S 61: Avoid release to the environment. Refer to special instructions/safety data sheets




MSDS 048.03 27 Oct 05

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