MATERIAL SAFETY DATA SHEET
CHONDROITINASE AC recombinant in sucrose 5%, 10 IU/mL,
RESEARCH GRADE
Revision 00 / July 2005
SECTION 1 - CHEMICAL PRODUCT AND COMPANY INFORMATION
IBEX Pharmaceuticals, Inc. Emergency Number: (514) 344-4004
5485 Par茅 Street
Montr茅al, Qu茅bec, H4P 1P7, CANADA Information Number: (514) 344-4004
Product Name: Chondroitinase AC, recombinant in sucrose 5%, 10 IU/mL Research
grade
Part Number: 50-013
SECTION 2 - COMPOSITION AND INFORMATION ON INGREDIENTS
CAS No.: 9047-57-8
EC No. 4.2.2.5
Systematic name: Chondroitin AC lyase
Synonyms: Chondroitin sulfate lyase
Chondroitin AC eliminase
chondroitinase
chondroitinase AC
Origin: Non-recombinant or recombinant, non-pathogenic microorganism
Ingredients: Recombinant in Sodium Phosphate; Sodium Chloride; Sucrose; water
Physical state: Aqueous solution; liquid or frozen
P/N 50-013 Chondroitinase AC, recombinant in sucrose 5%, 10 IU/mL, Research Grade
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IBEX PHARMACEUTICALS INC.
SECTION 3 - HAZARDS IDENTIFICATION
Emergency overview: Solution in water. Will not support burning. Not explosive.
Potential Health Effects:
Skin: May cause skin irritation
Eyes: May cause irritation or burning sensation
Inhalation: May cause irritation to the respiratory tract
Swallowed: Not known to cause toxic effects
Injection: Not known to cause toxicity
Carcinogenicity: Not determined
SECTION 4 - FIRST AID MEASURES
Skin contact: Flush with copious amounts of water.
Eye contact: Rinse opened eye for several minutes under running water. Then
consult a doctor.
Inhalation: Supply fresh air; consult doctor in case of complaints.
Swallowing: Wash mouth with plenty of water.
On all of the above: Consult a doctor if symptoms develop.
SECTION 5 - FIRE FIGHTING MEASURES
Suitable extinguishing agents: Noncombustible.
Protective equipment: No special measures required. Prevent contact with skin and eyes.
SECTION 6 - ACCIDENTAL RELEASE MEASURES
Person-related safety precautions: Prevent contact with skin and eyes. Ventilate area.
Measures for environmental protection: No special measures required.
Measures for cleaning/collecting: Spilled material should be carefully wiped up and
disposed as biomedical waste as per applicable waste disposal regulations. Wash spill site
after material pickup is complete.
Additional information:
P/N 50-013 Chondroitinase AC, recombinant in sucrose 5%, 10 IU/mL, Research Grade
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IBEX PHARMACEUTICALS INC.
SECTION 7 - HANDLING AND STORAGE
Handling
Information for safe handling: Prevent contact with skin and eyes and prevent inhalation
and swallowing. No other special precautions are necessary if used correctly.
Information about protection against explosions and fires: No special measures required.
Storage
Requirements to be met by storerooms and receptacles: No special requirements except
that product should be stored frozen (preferably at -70 掳C).
Information about storage in one common storage facility: Not required.
Further information about storage conditions: None
Storage class: None assigned
Class according to regulation on flammable liquids: Void
SECTION 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
General protective and hygienic measures: The usual precautionary measures for handling
chemicals and potentially biohazardous materials should be followed. Use clothing sufficient
to avoid skin contact. Safety shower and eye wash should be available in proximity.
Protection of hands: Use synthetic water resistant gloves.
Eye protection: Use safety glasses.
SECTION 9 - PHYSICAL AND CHEMICAL PROPERTIES
Physical form: Frozen, colorless, odorless aqueous solution.
(Chondroitinase AC is a protein)
Melting point: 0 掳C (melting point of aqueous solution)
Boiling point: Not applicable
Flash point: Not applicable
Flammability: Product is not flammable
Danger of explosion: Not determined
Solubility: Chondroitinase AC and ingredients are water soluble
Organic solvents: 0%
Solids content: 0%
P/N 50-013 Chondroitinase AC, recombinant in sucrose 5%, 10 IU/mL, Research Grade
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IBEX PHARMACEUTICALS INC.
SECTION 10 - STABILITY AND REACTIVITY
Thermal decomposition / conditions to be avoided: No decomposition if used according to
specifications.
Dangerous reactions: No dangerous reactions known.
Dangerous products of decomposition: No dangerous decomposition products known.
SECTION 11 - TOXICOLOGICAL INFORMATION
Effects of Acute Exposure: Not determined
Effects of Chronic Exposure: Not determined
Development Toxicity: Not determined
Reproductive Toxicity: Not determined
Mutagenicity: Not determined
Carcinogenicity: Not determined
P/N 50-013 Chondroitinase AC, recombinant in sucrose 5%, 10 IU/mL, Research Grade
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IBEX PHARMACEUTICALS INC.
SECTION 12 - ECOLOGICAL INFORMATION
General notes: Not available.
SECTION 13 - DISPOSAL CONSIDERATIONS
General notes: Dispose of in accordance with applicable regulations.
SECTION 14 - TRANSPORATION INFORMATION
D.O.T. shipping name: Chondroitinase AC
This substance is considered to be non hazardous for transport.
SECTION 15 - REGULATIONS
Not available.
SECTION 16 - OTHER INFORMATION
This information is given without any warranty or representation. It is believed to be
correct but does not claim to be all inclusive and shall be used only as a guide. IBEX
Pharmaceuticals Inc. shall not be held liable for any damage resulting from handling or
contact with the above product. It is offered solely for your consideration, investigation
and verification.
P/N 50-013 Chondroitinase AC, recombinant in sucrose 5%, 10 IU/mL, Research Grade
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IBEX PHARMACEUTICALS INC.
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