Search    ENTER KEYWORD
MSDS Material Safety Data Sheet
CAS

22-38-4
28-32-5
28-45-6

File Name: hycorbiomedical_com---Msds_030.05-substrate.asp
                                                                                                           Page 1 of 5
HYCOR BIOMEDICAL INC.
MATERIAL SAFETY DATA SHEET
1. IDENTIFICATION OF THE SUBSTANCE/PREPARATION AND OF THE COMPANY
Commercial Product: ALLERGY REAGENTS - SUBSTRATE

Name: Specific IgE, Total IgE and Specific IgG EIA - Substrate Diluent

List Number(s): Used in 72004, 72008, 74100, 74108, 74114, 74123, 74155, 76613, 308050, 319003, 72007
Xn
Product Classification: Component of in vitro diagnostic device

Manufacturer Company: Hycor Biomedical Inc. Distributor: (As appropriate)
7272 Chapman Ave.
Garden Grove, CA 92841 (USA)

Emergency Telephone No.:
USA No. 1-(714)- 933-3000 Attention: Randy Wilson
2. CHEMICAL CHARACTERIZATION/INFORMATION ON INGREDIENTS

Composition: Bottles contain 0.02% Sodium Azide (NaN3), 10% diethanolamine and 0.01% magnesium chloride
(MgCl2).
Hazardous substances: diethanolamine, sodium azide
See EEC directive 67/548 and amendments.

Substance %w/w Health Class CAS No. EINECS No. ANNEX 1
Diethanolamine(2,2鈥檌minodiethanol) 10% Xn R:22-38-41-48/22 111-42-2 203-868-0 603-071-00-1
S: (2)-26-36/37/39-46
Sodium azide (sodium azoture) 0.02% T+: N R:28-32-50/53 26628-22-8 247-852-1 011-004-00-7
S: (1/2)-28-45-60-61

See section 16 for spelling of R and S phrases.
3. HAZARDS IDENTIFICATION
Classification: Harmful if swallowed; risk of serious damage to eyes.
Warnings: May cause severe mucous irritation to the gastro-intestinal tract.
Contact with eyes may cause severe irritation and corneal damage.
Main exposure risks and symptoms:
Contact with eyes: vapor may cause irritation, tears, redness and pain. Contact may cause severe irritation and
corneal damage. May cause burns.
Ingestion: single dose oral toxicity is low. Swallowing large amounts may cause severe mucosal irritation,
lesions to mouth, esophagus, or gastro-intestinal tract. May also cause abdominal pain, nausea,
vomiting and diarrhea.
Inhalation: low vapor pressure makes it a low inhalation hazard unless heated or misted. Vapor or mist cause
irritation to the respiratory tract. Do not breath fumes.
Contact with skin: may cause irritation and redness. May also cause an allergic reaction. May be absorbed
through skin.
Chronic exposure: prolonged or repeated skin exposure may causes dermatitis. Animal studies have shown
target organ effects on the liver and kidney.




MSDS 030.05 17 Oct 05
Page 2 of 5

Commercial Product: ALLERGY REAGENTS - SUBSTRATE
4. FIRST AID MEASURES
Ingestion: Do not induce vomiting. Give large quantities of water, keeping patient conscious.
Never give anything by mouth to an unconscious person. Seek medical attention immediately.
Skin Contact: Flush skin immediately with water from at least 15 minutes. Wash area with soap and water. Remove
contaminated clothing and wash before reuse.
Eye contact: Promptly wash eye with plenty of water for at least 15 minutes, lifting eyelids occasionally; seek medical
advice immediately.
Inhalation: Irritant - remove from the origin of exposure and keep patient in contact with fresh air. If patient is not
breathing arrange to artificial respiration. If patient has a labored respiration, dispense an oxygen supply. Call a
physician. In any case consult a physician and show the container and/or label.
Direction for Physician: Symptomatic treatment by a physician.
5. FIRE-FIGHTING MEASURES
Extinguishing Media: dry chemical, foam or carbon dioxide. Do not use water.
Special Fire Fighting Procedures: In case of fire, wear a respirator with an organic vapor cartridge and particulate filter
(eg. Half-face respirator NIOSH type N95 or better filter; full face respirator NIOSH N 100 filter)
Unusual Fire Fighting Procedures: Keep away from heat, sparks and flames.
Thermal Decomposition: emits toxic fumes under fire conditions.
6. ACCIDENTAL RELEASE MEASURES
Steps To Be Taken After Spillage: Wear appropriate personal protective equipment as specified in Section 8. Dilute
liquids with water and absorb with an inert material and place in a chemical waste container for disposal. Wash
contaminated area with dilute bleach or soap.
Absorbant Material: vermiculite, dry sand, earth. Do not use combustible materials, as sawdust.
Waste Disposal Method: Consult a specialist for disposal of the spilled substance.
7. HANDLING AND STORAGE
Handling: Keep in its original container, tightly closed . Protect from physical damage. Open and handle container
carefully. Use in a chemical fume hood. Wear heavy rubber gloves, safety goggles and protective clothing. Do not
swallow. Do not breathe vapor. Avoid contact with eyes and skin.
Storage: Store between +2掳C (35,6掳F) and +8掳C (46,4掳F).
Other Precautions: Do not store near heat or ignition sources.
8. EXPOSURE CONTROLS/PERSONAL PROTECTION
Product TLV: Not known.
Diethanolamine (pure substance) TLV: 2 mg/m3 (TWA) skin
Sodium azide TLV (pure substance): 0.29 mg/m3 (Ceiling)
Respiratory Protection: Use in a chemical fume hood. Do not breathe vapor. Work in well-ventilated areas.
Eye Protection Protective chemical safety goggles or a full face shield where splashing is possible (8-inch minimum).
Maintain eye wash fountain and quick-drench facilities in work area.
Hand Protection: Protective chemical resistant rubber gloves. Wash thoroughly after handling.
Other Protective Equipment: Protective Clothing. Wash contaminated clothing before reuse.
Avoid prolonged or repeated exposure.



MSDS 030.05 17 Oct 05
Page 3 of 5
Commercial: ALLERGY REAGENTS - SUBSTRATE

9. PHYSICAL AND CHEMICAL PROPERTIES

Physical State: Liquid Ignition Temperature: N/A

Color: N/A Explosion limits: N/A

Odor: N/A Vapor Pressure: N/A

pH Value: 9.8 Solubility In Water: Soluble

Boiling Point: N/A In: N/A

Melting Point: N/A Viscosity: N/A

Flash Point: N/A
10. STABILITY AND REACTIVITY
Stable under ordinary conditions of use and storage.
Conditions to avoid: hygroscopic. Darkens upon heating above 60掳C (140掳F). This product should not be heated above
60掳C in the presence of aluminium due to excessive corrosion and potential chemical reaction releasing flammable
hydrogen gas.
Hazardous Decomposition Products: Burning may produce carbon monoxide, carbon dioxide, nitrogen oxides.
Hazardous Polymerization: will not occur.
Incompatibilities: carbon dioxide, copper, galvanized iron, halogenated organic solvents, acids and oxidizing agents. Do
not add with nitrites (N-nitrosamines may be formed).
Conditions to avoid: heat, flame, and ignition sources.
11. TOXICOLOGICAL INFORMATION

Referred to diethanolamine (in pure form)
Referred to the product:
LD50 Oral (rat): 620 碌L/kg
LD50 Oral: Not known
LD50 Skin (rabbit): 7,640 碌L/kg
LD50 Skin: Not known
LD50 Inhalation: not determined
LD50 Inhalation: Not known
Irritation, skin (rabbit): (Draize) 500 mg/24h mild
Irritation, skin: Not known
Irritation, eyes (rabbit): (Draize) 750 mg/24h severe
Irritation, eyes: Not known
IARC category: 3 (not classified as a human carcinogen)

Referred to sodium azide (in pure form):
LD50 Oral (rat): 27 mg/kg
LD50 Oral (mouse): 27 mg/kg
LDLO Oral (woman): 14 mg/kg
LDLO Oral (man): 29 mg/kg
LC50 Inhalation (rat): 37 mg/m3
LD50 Skin (rat): 50 mg/kg
LD50 Skin (rabbit): 20 mg/kg
LD50 Subcutaneous (rat): 45100 碌g/kg
LD50 Intravenous (rat): 47500 碌g/kg
IARC category: none

Toxicological Information: Product is harmful if swallowed; it may cause severe irritation to the gastro-intestinal tract.
Moderately toxic by intraperitoneal and subcutaneous routes. Mildly toxic by skin contact. Contact with eyes may cause
severe irritation and corneal damage.



MSDS 030.05 17 Oct 05
Page 4 of 5

Commercial: ALLERGY REAGENTS - SUBSTRATE

12. ECOLOGICAL INFORMATION

Use product according with good laboratory practices and avoid to release to the environment.
Ecotoxicity (aquatic toxicity): Product contains 0,02% sodium azide. Sodium azide concentration is below EC directives
allowed limits (0,25%, w/w). So, product is classified as not harmful to the aquatic environment, according to the
legislation in force (1999/45/CE and amendments). However, because sodium azide LC50/96H values for fish are less
than 1 mg/L, do not empty product into water or drains.
Mobility: Product is not expected to selectively partition and absorb to soil or sediments.
Persistence and Degradability: when released into the soil, or into water, this product is not expected to persist in the
environment.
Bioaccumulative potential: The product is not expected to significantly bioaccumulate (diethanolamine, in pure form, Kow
value => log Kow= -1,43).
Other adverse effects: None
13. DISPOSAL CONSIDERATIONS

Observe all Federal, State and Local laws concerning Health and Pollution.
14. TRANSPORT INFORMATION

Transport in accordance with national and international regulations.
Is not subject to current regulations for transportation of hazardous goods (eg. GGUS/ADR, GGUE/RID,
IMDG,IATA/ICAD).
Must be transport at controlled temperature (2梅8 掳C; 36.6梅46.4 掳F). Do not compromise container integrity.


15. REGULATORY INFORMATION
Label information:


Hazard Symbol: Xn
Xn

Indication of danger: harmful

Risk phrases: R: 22-41-48/22

R 22: Harmful if swallowed
R 41: Risk of serious damage to eyes
R 48/22: Harmful: danger of serious damage to health by prolonged exposure if swallowed

Safety phrases: S: 26-36/37/39-46

S 26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S 36/37/39: Wear suitable protective clothing, gloves and eye/face protection
S 46: If swallowed, seek medical advice immediately and show this container or label




MSDS 030.05 17 Oct 05
Page 5 of 5

Commercial: ALLERGY REAGENTS - SUBSTRATE

16. OTHER INFORMATION

The information herein is believed to be correct as of the date hereof but is provided without warranty of any kind. The
recipient of our products is responsible for observing any laws and guidelines applicable.
Use the product according with box insert and MSDS information. Please, read well instructions for use and warning.

Legend:
R phrases:
R 22: Harmful if swallowed
R 28: Very toxic if swallowed
R 32: Contact with acids liberates very toxic gas
R 38:Irritating to skin
R 41: Risk of serious damage to eyes
R48/22: Harmful: danger of serious damage to health by prolonged exposure if swallowed
R 50/53: Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.

S phrases:
S 1/2:Keep locked up and out of the reach of children
S 2:Keep out of the reach of children
S 26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S 28: After contact with skin, wash immediately with plenty of water
S 36/37/39: Wear suitable protective clothing, gloves and eye/face protection
S 45: In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible)
S 46: If swallowed, seek medical advice immediately and show this container or label
S 60: This material and its container must be disposed of as hazardous waste
S 61: Avoid release to the environment. Refer to special instructions/safety data sheets




MSDS 030.05 17 Oct 05

Search    ENTER KEYWORD
ALL Chemical Property And Toxicity Analysis PAGES IN THIS GROUP
NAMECAS
hp_com---pcgreenlabel.asp N/A
hp_com---supcode.asp N/A
hse_gov_uk---indg353.asp N/A
Hurricane.asp 111-76-2
hycorbiomedical_com---87155.asp 9002-88-4
hycorbiomedical_com---MSDS_01_07_Kova_Trol-2006-Abnormal.asp 13746-66-2 151-50-8 28-29-4
hycorbiomedical_com---Msds_030.05-substrate.asp 22-38-4 28-32-5 28-45-6
hycorbiomedical_com---MSDS_031_05-allergen_disc.asp 28-32-5 28-45-6
hycorbiomedical_com---MSDS_048_03-HYTEC_Calibrators.asp 28-32-5 28-45-6
hycorbiomedical_net---MSDS_03.03-LiquaTrol.asp 13746-66-2 151-50-8 28-29-4 28836-03-5
hycordiagnostics_com---MSDS_050_04_IgE_sample_diluent.asp 28-32-5 28-45-6
hycordx_com---MSDS_01.05-KovaTrol.asp 13746-66-2 151-50-8 28-29-4
hycordx_com---MSDS_03_04-LiquaTrol.asp 13746-66-2 151-50-8 28-29-4 28836-03-5
hydro-gardens_com---Calcium_Nitrate.asp 15245-12-2
hyvac_com---Flushing_Oil_MSDS.asp 64741-88-4
iaq-usa_com---Shockwave_MSDS.asp 7732-18-5 68391-01-5 68956-79-6 9016-45-9 497-19-8 64-02-8
ibex_ca---50-013_ChonAC_rec_sucrose_5_10IUmL_Rev00_Jul05.asp 9047-57-8
ifa_hawaii_edu---Nickel_Alloys.asp N/A
iftkorea_co_kr---GetekFR4PrepregMSDSDecember2006Final.asp 65997-17-3 80-05-7 37-41-4 85-68-7 84-74-2
igcl_com---MSDS.asp N/A
igs_nigc_ir---M-SF-233.asp N/A
iko_com---1511MsdscInsulIkothermCrc.asp N/A
iko_com---1911MsdscInsulIkothermHr.asp N/A
image_snapon_com---blpbc18_blpbc24_blpbc30_blpbc36.asp N/A
image_snapon_com---blpgss1462npa.asp N/A
image_snapon_com---blpptss3822.asp N/A
image_snapon_com---btqs500_btqs600_btqshd400_btqs1000npa.asp N/A
image_snapon_com---cj9180npa.asp N/A
image_snapon_com---exdms48npa.asp N/A
image_snapon_com---fsdr_fsdr9pk.asp N/A
image_snapon_com---glove301_glove302.asp N/A
image_snapon_com---imdm390.asp N/A
image_snapon_com---lbuk3_lbuk3pk.asp N/A
image_snapon_com---ldtsp4.asp N/A
image_snapon_com---stsm18e.asp N/A
image_snapon_com---torch6.asp N/A
image_snapon_com---uim2lt.asp N/A
imaging_mallinckrodt_com---Gallium_Citrate.asp 41183-64-6 7647-14-5 100-51-6 6132-04-3 7732-18-5
immcodiagnostics_com---M1027K.asp N/A
industrialbolt_com---BrakePartsCleanerII.asp 110-54-3 64-17-5 124-38-9 67-56-1
industrialbolt_com---ChokeCarbCleaner.asp 108-88-3 67-56-1 67-64-1 124-38-9
innotrac_fi---ddimer.msds.en.asp N/A
innotrac_fi---hcg.msds.se.asp N/A
innotrac_fi---msds.gr.Buffer.concentrate.asp 10035-04-8 78491-02-8 6381-92-6 7365-45-9 9005-64-5
innotrac_fi---troponin.msds.en.asp N/A
innovationinks_ca---msds.asp 64742-46-7 61789-52-4 8030-70-4
inovadx_com---508509.asp 7664-93-9 7732-18-5
interferonsource_com---MSDS4004_Human-IFN_Omega_ELISA_kit.asp 55965-84-9
invitrogen_com---11668.asp N/A
invivogen_com---MSDS_EKLPS.asp 20-01-0 23-09-0

Free MSDS Search ( Providing 250,000+ Material Properties )
Chemcas.com | Ads link:todaystock.net