KEM
EN
TEC
Material Safety Data Sheet according to 91/155/EEC
Diagnostics
Kem-En-Tec Diagnostic s
Day of issue: 9. september 2005 Day of revision: 12. December 2005
1. Identification of the substance/preparation and of the company
Trade names
p-NPP substrate cat. no. 4400
Use
Material Safety Data Sheet
For research and analysis
Manufacturer/Supplier
See below.
Telephone/Telefax
See below.
Emergency telephone
+45 39 27 17 71
2. Composition/Information on ingredients
% w/w Chemical name CAS no. EINECS/ELINCS Classification Note
App. 6 Trizma base 77-86-1 201-064-4 Xi;R36/38 1
1: Trizma base = Tris(hydroxymethyl)aminomethane
Wording of R-phrases - see section 16.
3. Hazards identification
Particular information pertaining specific risk for human and environment
The health risk is low - see section 15.
4. First aid measures
Inhalation
Go to fresh air. Keep at rest. If person feels queasy/discomfort: seek medical advise.
Skin contact
Remove contaminated clothing and wash skin with water and mild soap.
Eye contact
Flush thoroughly with water or physiological salt water. Remember to remove contact
lenses, if any. If irritation persist: seek medical advice.
Ingestion
Rinse mouth and drink plenty of water. If needed: seek medical advice.
Information
Show this Safety Data Sheet to a physician or emergency ward.
5. Fire-fighting measures
Flammability
Non-combustible
Extinguishing media - suitable
Not relevant.
Special risks in a fire situation
Not relevant
Protective equipment
Not relevant
K ul dy s s en 1 0
Kem-E n-Tec Di agnostics A/S D K -2 6 3 0 T a as t ru p T el. : (4 5) 3 9 27 1 77 1 E- m a il: s u pp ort @ k em -e n -t ec . c o m
D e nm ar k F ax : ( 4 5) 3 92 0 0 17 8 w w w . k em - en -t ec . c o m
CVR: 2580 6735
KEM
EN
TEC
Trade name: p-NPP substrate
6. Accidental release measures
Diagnostics
Kem-En-Tec Diagnostic s
Personal precautions
Provide for sufficient ventilation/respiratory protection.
See protective equipment listed in section 8.
Environmental precautions
Do not empty into drains. See section 12. If the product contaminates sewages, inform
appropriate authorities in accordance with local regulations.
Material Safety Data Sheet
Methods for cleaning up/collecting
Absorb spilled liquid with a cloth, inert material or liquid-absorbent material. Read the
directions from the producer. Flush the area with water. For further treatment of the
spillage 鈥? see section 13.
7. Handling and storage
Safe handling
See section 8.
Safe storage
At 2 飩癈 鈥? 8 飩癈 in a sealed container.
Specific use(s):
See section 1.
8. Exposure controls/personal protection
Engineering measures (prevention of worker exposure)
After use wash with water and soap.
Personal protective equipment
Respiratory protection:
None
Skin protection:
Use protective gloves of nitrile rubber when there is a risk of direct
contact and splash.
Breakthrough time: unknown - change gloves if exposed
Eye protection:
Wear close-fitting safety goggles when risk of splashes during manufacture of solution.
Environmental exposure controls:
-
9. Physical and chemical properties
Appearance: Liquid
Solubility in water: Soluble
10. Stability and reactivity
Stability
Stable. Non-combustible
Conditions to avoid
-
Materials to avoid
-
Hazardous decomposition products
-
K ul dy s s en 1 0
Kem-E n-Tec Di agnostics A/S D K -2 6 3 0 T a as t ru p T el. : (4 5) 3 9 27 1 77 1 E- m a il: s u pp ort @ k em -e n -t ec . c o m
D e nm ar k F ax : ( 4 5) 3 92 0 0 17 8 w w w . k em - en -t ec . c o m
CVR: 2580 6735
KEM
EN
TEC
Trade name: p-NPP substrate
Diagnostics
Kem-En-Tec Diagnostic s
11. Toxicological information
Routes of exposure: May be absorbed through the skin, by inhalation and ingestion.
Acute toxicity:
Inhalation:
Inhalation of atomized liquid may cause irritation of the upper respiratory tract.
Skin:
Material Safety Data Sheet
Contact with the skin may cause irritation with redness
Eyes:
Contact with the eyes may cause irritation with redness.
Ingestion:
Ingestion of large amounts can cause irritation with nausea and stomach ache.
Long term toxicity:
-
12. Ecological information
Ecotoxicity:
-
Mobility:
Tris(hydroxymetnyl)aminomethane (Trizma base) is water soluble and is therefore
spread quickly in the aquatic environment.
Persistence and degradability:
According to computer calculation Trizma base is expected to be easily biodegradable.
Bioaccumulative potential:
Trizma base: LogKow<1 鈥? no significant bioaccumulative effect (computer calculation)
Other adverse effects:
-
13. Disposal considerations
Disposal should be according to local, state or national legislation. Dispose of through
authority facilities or pass to chemical disposal company.
EWC-code: 16 05 09
14. Transport information
Not dangerous goods
K ul dy s s en 1 0
Kem-E n-Tec Di agnostics A/S D K -2 6 3 0 T a as t ru p T el. : (4 5) 3 9 27 1 77 1 E- m a il: s u pp ort @ k em -e n -t ec . c o m
D e nm ar k F ax : ( 4 5) 3 92 0 0 17 8 w w w . k em - en -t ec . c o m
CVR: 2580 6735
KEM
EN
TEC
Trade name: p-NPP substrate
15. Regulatory information
Diagnostics
Kem-En-Tec Diagnostic s
Classification according to EEC directives
Contains:
-
Danger symbol and danger designation:
-
Risk- and Safetyphrases:
Material Safety Data Sheet
ALTox a/s has the 12. December concluded, that the preparation is not to be classified
according to EEC directive 88/379/EEC.
Restriction on application:
-
Requirements concerning special training
No special training is anticipated, however, the user should be well instructed for the
execution of his task, have knowledge of this Safety Data Sheet and normal training in
the use of personal protective equipment.
16. Other information
R-phrases mentioned in section 2:
R36/38: Irritating to eyes and skin
Edition no.: (Revision) Date: Changes in section(s):
02 12. December 2005 Change in address
This Material Safety Data Sheet was created by:
Altox a/s - Godthaabsvej 177 - DK-2720 Vanloese - Denmark
Tel. +45 38 34 77 98 - Fax +45 38 34 77 99 /KN - Quality control: PW
K ul dy s s en 1 0
Kem-E n-Tec Di agnostics A/S D K -2 6 3 0 T a as t ru p T el. : (4 5) 3 9 27 1 77 1 E- m a il: s u pp ort @ k em -e n -t ec . c o m
D e nm ar k F ax : ( 4 5) 3 92 0 0 17 8 w w w . k em - en -t ec . c o m
CVR: 2580 6735
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