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Roundup PRO庐 Herbicide Version: 1.2 Effective date: 04/21/2005
MONSANTO COMPANY
Material Safety Data Sheet
Commercial Product
1. PRODUCT AND COMPANY IDENTIFICATION
Product name
Roundup PRO庐 Herbicide
EPA Reg. No.
524-475
Product use
Herbicide
Chemical name
Not applicable.
Synonyms
None.
Company
MONSANTO COMPANY, 800 N. Lindbergh Blvd., St. Louis, MO, 63167
Telephone: 800-332-3111, Fax: 314-694-5557
Emergency numbers
FOR CHEMICAL EMERGENCY, SPILL LEAK, FIRE, EXPOSURE, OR ACCIDENT Call CHEMTREC - Day
or Night: 1-800-424-9300 toll free in the continental U.S., Puerto Rico, Canada, or Virgin Islands. For calls
originating elsewhere: 703-527-3887 (collect calls accepted).
FOR MEDICAL EMERGENCY - Day or Night: +1 (314) 694-4000 (collect calls accepted).
2. COMPOSITION/INFORMATION ON INGREDIENTS
Active ingredient
Isopropylamine salt of N-(phosphonomethyl)glycine; {Isopropylamine salt of glyphosate}
Composition
COMPONENT CAS No. % by weight (approximate)
Isopropylamine salt of glyphosate 38641-94-0 41
Other ingredients 59
Trade secret composition.
OSHA Status
This product is hazardous according to the OSHA Hazard Communication Standard, 29 CFR 1910.1200.
3. HAZARDS IDENTIFICATION
Emergency overview
Appearance and odour (colour/form/odour): Clear - Amber / Liquid / Sweet
CAUTION!
CAUSES EYE IRRITATION
Potential health effects
Likely routes of exposure
Skin contact, eye contact
Eye contact, short term
May cause temporary eye irritation.
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Roundup PRO庐 Herbicide Version: 1.2 Effective date: 04/21/2005
Skin contact, short term
Not expected to produce significant adverse effects when recommended use instructions are followed.
Inhalation, short term
Not expected to produce significant adverse effects when recommended use instructions are followed.
Refer to section 11 for toxicological and section 12 for environmental information.
4. FIRST AID MEASURES
Eye contact
If in eyes, hold eye open and rinse slowly and gently for 15-20 minutes. Remove contact lenses, if present, after
first 5 minutes, then continue rinsing.
Skin contact
Take off contaminated clothing, wristwatch, jewellery.
Wash affected skin with plenty of water.
Wash clothes and clean shoes before re-use.
Inhalation
Remove to fresh air.
Ingestion
Immediately offer water to drink.
Do NOT induce vomiting unless directed by medical personnel.
If symptoms occur, get medical attention.
Advice to doctors
This product is not an inhibitor of cholinesterase.
Antidote
Treatment with atropine and oximes is not indicated.
5. FIRE-FIGHTING MEASURES
Flash point
None.
Extinguishing media
Recommended: Water, foam, dry chemical, carbon dioxide (CO2)
Unusual fire and explosion hazards
Minimise use of water to prevent environmental contamination.
Environmental precautions: see section 6.
Hazardous products of combustion
Carbon monoxide (CO), phosphorus oxides (PxOy), nitrogen oxides (NOx)
Fire fighting equipment
Self-contained breathing apparatus.
Equipment should be thoroughly decontaminated after use.
6. ACCIDENTAL RELEASE MEASURES
Personal precautions
Use personal protection recommended in section 8.
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Roundup PRO庐 Herbicide Version: 1.2 Effective date: 04/21/2005
Environmental precautions
SMALL QUANTITIES:
Low environmental hazard.
LARGE QUANTITIES:
Minimise spread.
Keep out of drains, sewers, ditches and water ways.
Notify authorities.
Methods for cleaning up
SMALL QUANTITIES:
Flush spill area with water.
LARGE QUANTITIES:
Absorb in earth, sand or absorbent material.
Dig up heavily contaminated soil.
Collect in containers for disposal.
Refer to section 7 for types of containers.
Flush residues with small quantities of water.
Minimise use of water to prevent environmental contamination.
Refer to section 13 for disposal of spilled material.
7. HANDLING AND STORAGE
Good industrial practice in housekeeping and personal hygiene should be followed.
Handling
When using do not eat, drink or smoke.
Wash hands thoroughly after handling or contact.
Thoroughly clean equipment after use.
Do not contaminate drains, sewers and water ways when disposing of equipment rinse water.
Emptied containers retain vapour and product residue.
Refer to section 13 for disposal of rinse water.
Observe all labelled safeguards until container is cleaned, reconditioned or destroyed.
Storage
Minimum storage temperature: -15 掳C
Maximum storage temperature: 50 掳C
Compatible materials for storage: stainless steel, aluminium, fibreglass, plastic, glass lining
Incompatible materials for storage: galvanised steel, unlined mild steel, see section 10.
Keep out of reach of children.
Keep away from food, drink and animal feed.
Keep only in the original container.
Partial crystallization may occur on prolonged storage below the minimum storage temperature.
If frozen, place in warm room and shake frequently to put back into solution.
Minimum shelf life: 5 years.
8. EXPOSURE CONTROLS/PERSONAL PROTECTION
Airborne exposure limits
Components Exposure Guidelines
Isopropylamine salt of glyphosate No specific occupational exposure limit has been established.
Other ingredients No specific occupational exposure limit has been established.
Engineering controls
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Roundup PRO庐 Herbicide Version: 1.2 Effective date: 04/21/2005
No special requirement when used as recommended.
Eye protection
If there is significant potential for contact:
Wear chemical goggles.
Skin protection
If repeated or prolonged contact:
Wear chemical resistant gloves.
Respiratory protection
No special requirement when used as recommended.
When recommended, consult manufacturer of personal protective equipment for the appropriate type of equipment
for a given application.
9. PHYSICAL AND CHEMICAL PROPERTIES
These physical data are typical values based on material tested but may vary from sample to sample. Typical values
should not be construed as a guaranteed analysis of any specific lot or as specifications for the product.
Colour/colour range: Clear - Amber
Form: Liquid
Odour: Sweet
Flash point: None.
Specific gravity: 1.169 @ 20 掳C / 15.6 掳C
Vapour pressure: 25 mmHg 24 掳C
Solubility: Water: Completely miscible.
pH: 4.4 - 5.0
Partition coefficient (log Pow): -3.2 @ 25 掳C (glyphosate)
10. STABILITY AND REACTIVITY
Stability
Stable under normal conditions of handling and storage.
Hazardous decomposition
Thermal decomposition: Hazardous products of combustion: see section 5.
Materials to avoid/Reactivity
Reacts with galvanised steel or unlined mild steel to produce hydrogen, a highly flammable gas that could explode.
11. TOXICOLOGICAL INFORMATION
This section is intended for use by toxicologists and other health professionals.
Data obtained on product and components are summarized below.
Acute oral toxicity
Rat, LD50: 5,108 mg/kg body weight
Practically non-toxic.
FIFRA category IV.
Acute dermal toxicity
Rat, LD50 (limit test): > 5,000 mg/kg body weight
Practically non-toxic.
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Roundup PRO庐 Herbicide Version: 1.2 Effective date: 04/21/2005
FIFRA category IV.
No mortality.
Acute inhalation toxicity
Rat, LC50, 4 hours, aerosol: 2.9 mg/L
Other effects: weight loss, breathing difficulty
Practically non-toxic.
FIFRA category IV.
Skin irritation
Rabbit, 6 animals, OECD 404 test:
Days to heal: 3
Primary Irritation Index (PII): 0.5/8.0
Essentially non irritating.
FIFRA category IV.
Eye irritation
Rabbit, 6 animals, OECD 405 test:
Days to heal: 3
Slight irritation.
FIFRA category III.
Skin sensitization
Guinea pig, Buehler test:
Positive incidence: 0 %
N-(phosphonomethyl)glycine; {glyphosate}
Mutagenicity
In vitro and in vivo mutagenicity test(s):
Not mutagenic.
Repeated dose toxicity
Rabbit, dermal, 21 days:
NOAEL toxicity: > 5,000 mg/kg body weight/day
Target organs/systems: none
Other effects: none
Rat, oral, 3 months:
NOAEL toxicity: > 20,000 mg/kg diet
Target organs/systems: none
Other effects: none
Chronic effects/carcinogenicity
Mouse, oral, 24 months:
NOEL tumour: > 30,000 mg/kg diet
NOAEL toxicity: ~ 5,000 mg/kg diet
Tumours: none
Target organs/systems: liver
Other effects: decrease of body weight gain, histopathologic effects
Rat, oral, 24 months:
NOEL tumour: > 20,000 mg/kg diet
NOAEL toxicity: ~ 8,000 mg/kg diet
Tumours: none
Target organs/systems: eyes
Other effects: decrease of body weight gain, histopathologic effects
Toxicity to reproduction/fertility
Rat, oral, 3 generations:
NOAEL toxicity: > 30 mg/kg body weight
NOAEL reproduction: > 30 mg/kg body weight
Target organs/systems in parents: none
Other effects in parents: none
Target organs/systems in pups: none
Other effects in pups: none
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Roundup PRO庐 Herbicide Version: 1.2 Effective date: 04/21/2005
Developmental toxicity/teratogenicity
Rat, oral, 6 - 19 days of gestation:
NOAEL toxicity: 1,000 mg/kg body weight
NOAEL development: 1,000 mg/kg body weight
Other effects in mother animal: decrease of body weight gain, decrease of survival
Developmental effects: weight loss, post-implantation loss, delayed ossification
Effects on offspring only observed with maternal toxicity.
Rabbit, oral, 6 - 27 days of gestation:
NOAEL toxicity: 175 mg/kg body weight
NOAEL development: 175 mg/kg body weight
Target organs/systems in mother animal: none
Other effects in mother animal: decrease of survival
Developmental effects: none
12. ECOLOGICAL INFORMATION
This section is intended for use by ecotoxicologists and other environmental specialists.
Data obtained on product and components are summarized below.
Aquatic toxicity, fish
Rainbow trout (Oncorhynchus mykiss):
Acute toxicity, 96 hours, static, LC50: 5.4 mg/L
Moderately toxic.
Bluegill sunfish (Lepomis macrochirus):
Acute toxicity, 96 hours, static, LC50: 7.3 mg/L
Moderately toxic.
Aquatic toxicity, invertebrates
Water flea (Daphnia magna):
Acute toxicity, 48 hours, static, EC50: 11 mg/L
Slightly toxic.
Avian toxicity
Mallard duck (Anas platyrhynchos):
Dietary toxicity, 5 days, LC50: > 5,620 mg/kg diet
Practically non-toxic.
Bobwhite quail (Colinus virginianus):
Dietary toxicity, 5 days, LC50: > 5,620 mg/kg diet
Practically non-toxic.
Arthropod toxicity
Honey bee (Apis mellifera):
Oral/contact, 48 hours, LD50: > 100 碌g/bee
Practically non-toxic.
Soil organism toxicity, invertebrates
Earthworm (Eisenia foetida):
Acute toxicity, 14 days, LC50: > 1,250 mg/kg soil
Practically non-toxic.
N-(phosphonomethyl)glycine; {glyphosate}
Bioaccumulation
Bluegill sunfish (Lepomis macrochirus):
Whole fish: BCF: < 1
No significant bioaccumulation is expected.
Dissipation
Soil, field:
Half life: 2 - 174 days
Koc: 884 - 60,000 L/kg
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Roundup PRO庐 Herbicide Version: 1.2 Effective date: 04/21/2005
Adsorbs strongly to soil.
Water, aerobic:
Half life: < 7 days
13. DISPOSAL CONSIDERATIONS
Product
Excess product may be disposed of by agricultural use according to label instructions.
Keep out of drains, sewers, ditches and water ways.
Recycle if appropriate facilities/equipment available.
Burn in proper incinerator.
Follow all local/regional/national/international regulations.
Container
See the individual container label for disposal information.
Emptied containers retain vapour and product residue.
Observe all labelled safeguards until container is cleaned, reconditioned or destroyed.
Empty packaging completely.
Store for collection by approved waste disposal service.
Ensure packaging cannot be reused.
Do NOT re-use containers.
Recycle if appropriate facilities/equipment available.
Follow all local/regional/national/international regulations.
14. TRANSPORT INFORMATION
The data provided in this section is for information only. Please apply the appropriate regulations to properly
classify your shipment for transportation.
Not hazardous under the applicable DOT, ICAO/IATA, IMO, TDG and Mexican regulations.
15. REGULATORY INFORMATION
TSCA Inventory
All components are on the US EPA's TSCA Inventory
OSHA Hazardous Components
Surfactant
SARA Title III Rules
Section 311/312 Hazard Categories
Immediate
Section 302 Extremely Hazardous Substances
Not applicable.
Section 313 Toxic Chemical(s)
Not applicable.
CERCLA Reportable quantity
Not applicable.
16. OTHER INFORMATION
The information given here is not necessarily exhaustive but is representative of relevant, reliable data.
Follow all local/regional/national/international regulations.
Please consult supplier if further information is needed.
In this document the British spelling was applied.
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Roundup PRO庐 Herbicide Version: 1.2 Effective date: 04/21/2005
Health Flammability Instability Additional Markings
NFPA 1 1 1
0 = Minimal hazard, 1 = Slight hazard, 2 = Moderate hazard, 3 = Severe hazard, 4 = Extreme hazard
Full denomination of most frequently used acronyms. BCF (Bioconcentration Factor), BOD (Biochemical Oxygen Demand), COD (Chemical
Oxygen Demand), EC50 (50% effect concentration), ED50 (50% effect dose), I.M. (intramuscular), I.P. (intraperitoneal), I.V. (intravenous), Koc
(Soil adsorption coefficient), LC50 (50% lethality concentration), LD50 (50% lethality dose), LDLo (Lower limit of lethal dosage), LEL (Lower
Explosion Limit), LOAEC (Lowest Observed Adverse Effect Concentration), LOAEL (Lowest Observed Adverse Effect Level), LOEC (Lowest
Observed Effect Concentration), LOEL (Lowest Observed Effect Level), MEL (Maximum Exposure limit), MTD (Maximum Tolerated Dose),
NOAEC (No Observed Adverse Effect Concentration), NOAEL (No Observed Adverse Effect Level), NOEC (No Observed Effect
Concentration), NOEL (No Observed Effect Level), OEL (Occupational Exposure Limit), PEL (Permissible Exposure Limit), PII (Primary
Irritation Index), Pow (Partition coefficient n-octanol/water), S.C. (subcutaneous), STEL (Short-Term Exposure Limit), TLV-C (Threshold Limit
Value-Ceiling), TLV-TWA (Threshold Limit Value - Time Weighted Average), UEL (Upper Explosion Limit)
This Material Safety Data Sheet (MSDS) serves different purposes than and DOES NOT REPLACE
OR MODIFY THE EPA-APPROVED PRODUCT LABELING (attached to and accompanying the
product container). This MSDS provides important health, safety, and environmental information for
employers, employees, emergency responders and others handling large quantities of the product in
activities generally other than product use, while the labeling provides that information specifically for
product use in the ordinary course. Use, storage and disposal of pesticide products are regulated by
the EPA under the authority of the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA)
through the product labeling, and all necessary and appropriate precautionary, use, storage, and
disposal information is set forth on that labeling. It is a violation of federal law to use a pesticide
product in any manner not prescribed on the EPA-approved label.
Although the information and recommendations set forth herein (hereinafter "Information") are
presented in good faith and believed to be correct as of the date hereof, MONSANTO Company or any
of its subsidiaries makes no representations as to the completeness or accuracythereof. Information is
supplied upon the condition that the persons receiving same will make their own determination as to
its suitability for the purposes prior to use. In no event will MONSANTO Company or any of its
subsidiaries be responsible for damages of any nature whatsoever resulting from the use of or reliance
upon information. NO REPRESENTATIONS OR WARRANTIES, EITHER EXPRESS OR
IMPLIED, OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE OR OF ANY
OTHER NATURE ARE MADE HEREUNDER WITH RESPECT TO INFORMATION OR TO THE
PRODUCT TO WHICH INFORMATION REFERS.
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