P Product # (s)_520-007, 1024262
MATERIAL SAFETY DATA SHEET
Section 1. Company Identification and Product Information
Product Name or Identity: Yeast and Mold Supplement, YI-110B
Neogen Corporation 517/372-9200
Manufacturer鈥檚 Name: Emergency Phone No.:
620 Lesher Place 517/372-0108
Fax No.:
Lansing, MI 48912 foodsafety@neogen.com
e-mail:
Date Prepared or Revised: 04/19/07
Section 2. Composition / Information on Ingredients
Hazardous Components CAS-No. % EG-Number Hazard
Specific Chemical Identity: Symbol
Chlortetracycline 64-72-2 50% N/A Xi
Chloramphenicol 56-75-7 50% N/A T
Section 3. Health Hazard Identification
Inhalation? Yes Skin? Yes Ingestion? Yes
Route(s) of Entry:
Toxic. Toxic by inhalation, contact with skin, and if swallowed. Irritating to eyes, respiratory
Health Hazards:
system, and skin. Possible risk of harm to unborn child. Possible carcinogen.
(Acute and Chronic)
IARC Monographs? 2A (Chloramphenicol) OSHA Regulated? No
Carcinogenicity:
This agent is probably carcinogenic to humans.
Signs and Symptoms of Exposure: Exposure to Chloramphenicol may cause nausea, headache, and vomiting.
Irritating effect to skin, eyes, and mucous membranes. Ingestion may cause nausea, vomiting, and diarrhea.
Medical Conditions Generally Aggravated by Exposure: Based on laboratory animal data, chronic exposure may
cause reproductive disorders. Increased exposure to Chloramphenicol may cause depression of the bone marrow and
blood abnormalities. Prolonged or repeated exposure may cause allergic reactions in certain sensitive individuals.
Section 4. First Aid Measures
General Information: Immediately remove contaminated clothing. Show physician product label.
Emergency /
First Aid
Ingestion: If swallowed, seek medical attention immediately. DO NOT INDUCE VOMITING.
Procedures:
Inhalation: If inhaled, supply fresh air or oxygen. Seek medical attention. If breathing is difficult, give
oxygen. In case of unconsciousness, place patient on side position for transportation.
Eye Contact: Rinse opened eye for at least 15 minutes under running water, lifting lower and upper
eyelids occasionally. Seek medical attention.
Skin Contact: Remove contaminated clothing immediately. Wash with plenty of soap and water for at
least 15 minutes. Seek medical attention. Wash clothing before reuse.
Section 5. Fire and Explosion Hazard Data
Flash Point (Method Used): Closed Cup Flammable Limits:
UEL: (Upper Explosive Limit): N/A
LEL: (Lower Explosive Limit): N/A
210掳C (Chlortetracycline)
Extinguishing Media: Use alcohol foam, dry chemical, or carbon dioxide.
Special Fire Fighting Procedures: Above flash point, vapor-air mixtures can be explosive. Moderate explosion hazard
and dangerous fire hazard when exposed to heat, sparks, or flames. Sensitive to static discharge. Firefighters should
wear protective equipment and self-contained breathing apparatus.
Unusual Fire and Explosion Hazards: During heating or in case of fire, poisonous gases are produced. Fine dust
dispersed in air in sufficient concentrations, and in the presence of an ignition source, is a potential dust explosion hazard.
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P Product # (s)_520-007, 1024262
Section 6. Accidental Release Measures
Personal Precautions: Shut off all sources of ignition, ventilate spill area. Consider need for evacuation. Wear suitable
protective clothing, gloves, and eye protection. Avoid inhalation and contact with skin and eyes. Wear self-containing
breathing apparatus, rubber boots, and heavy rubber gloves. Place contaminated material in a chemical waste container.
Environmental Precautions: Prevent dispersion of material. Do not allow to enter drains or water courses.
Clean-up Methods: Contact safety officer and ventilate area. Absorb spill with inert material, including dry-lime, sand, or
soda ash, then place into a chemical waste container using non-sparking tools. Wash spill site.
Section 7. Handling and Storage
Handling: Ensure good ventilation / exhaustion and do not breathe vapor. Avoid contact with eyes, skin, and clothing.
Avoid prolonged or repeated exposure. Do not use if skin is cut or scratched.
Storage: Keep container tightly closed, protect from light, moist air, and steam. Store away from oxidizing agents. Keep
away from heat, sparks, and open flame. Storage area should be cool, dry, and away from incompatible materials.
Containers of this material may be hazardous when empty since they retain product residues.
Section 8. Exposure Controls / Personal Protection
ACGIH TLV: N/A
OES: N/A
Engineering Measures: In the event of use above flash point, use in closed systems. Do not use compressed air by filling,
discharging or handling the product. Proper ventilation required. Safety shower and eye bath. Use adequate general or local
exhaust ventilation to keep airborne concentrations below the permissible exposure limits.
Respiratory Protection (Specify Type): With sufficient ventilation, breathing apparatus is not necessary. In the event of
possible spill / exposure use dusk mask to (US) N100 or EN 143 FFP2S
Local Exhaust: 50 鈥? 100 CFM Special: N/A
Ventilation:
Mechanical (General): N/A Other: N/A
Protective Gloves: Compatible chemical-resistant gloves. Eye Protection: Safety glasses or chemical goggles to
EN 166, 167, and 168
Other Protective Clothing or Equipment: Uniform, lab coat, or disposable lab wear.
Work / Hygienic Practices: Follow the usual precautionary measure for handling chemicals / powder. Keep away from
food and beverages. Immediately remove all soiled and contaminated clothing. Avoid contact with eyes, skin, and clothing.
Section 9. Physical and Chemical Properties
Boiling Point: N/A Specific Gravity: N/A
Vapor Pressure (mm Hg.): N/A Melting Point: 150掳C (Chloramphenicol), 220掳C (Chlorotetracycline)
Vapor Density (AIR = 1): 11.1 (Chloramphenicol) Solubility in Water: Soluble in water (Chloramphenicol)
17.8 (Chlorotetracycline)
Appearance and Odor: Solid, light beige, characteristic odor (Chloramphenicol), Solid yellow, odorless (Chlorotetracycline).
Section 10. Stability and Reactivity
Unstable
Stability:
Stable X Conditions to Avoid: Avoid exposure to light and moisture. May degrade on
exposure to light.
Incompatibility (Materials to Avoid): Incompatible with strong oxidizing agents, acids, acid chlorides, and acid
anhydrides.
Hazardous Decomposition or Byproducts: Carbon dioxide (CO2), Carbon monoxide (CO), Nitrogen oxides, and
Hydrogen chloride gas.
May Occur
Hazardous
Polymerization:
Will Not X Conditions to Avoid: Light, moisture, and incompatible materials.
Occur
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Product # (s)_520-007, 1024262
Section 11. Toxicological Information
LD50: ORL-RAT, 2500 mg/kg (Chloramphenicol) LD50: ORL-MSE, 2314 mg/kg (Chlorotetracycline)
LD50: INV-RAT, 171 mg/kg (Chloramphenicol) LD50: INV-RAT, 100 mg/kg (Chlorotetracycline)
Section 12. Ecological Information
Ecotoxicity Tests: EC50 Daphnia, (Daphnia magna), 48 H, 345 mg/L (Chloramphenicol)
Section 13. Disposal Considerations
Waste Disposal Method: Dispose in accordance with all applicable federal, state, and local environmental regulations.
Keep waste separate. Contact a licensed professional waste disposal service to dispose of this material. (DN) requires this
material to have a special label: 鈥淐ontains a substance which is regulated by Dannish work environmental law due to the
risk of carcinogenic properties鈥?. Do not allow product to reach ground water, water bodies, or sewage system. Burn in a
chemical incinerator equipped with an afterburner and scrubber but exert extra care in igniting as this material is highly
flammable.
Container Information: Do not remove labels from containers.
Section 14. Transport Information
Chloramphenicol: Chlorotetracycline:
Non-Hazardous for transportation: This substance Non-Hazardous for transportation: This substance is considered to be
is considered to be non-hazardous for transport. non-hazardous for transport.
Section 15. Regulatory Information
EU Regulations
Hazard Symbol(s):
Chlortetracycline: Xi (Irritant)
Chloramphenicol: T (Toxic)
Risk Phrases:
Chlortetracycline: R 36 / 37 / 38 Irritating to eyes, respiratory system and skin.
Chloramphenicol: R 45 May cause cancer.
Safety Phrases:
Chlortetracycline: S 26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
Chloramphenicol: S 53 鈥? 54 Avoid exposure 鈥? obtain special instructions before use. In case of accident or if you feel
unwell, seek medical advice immediately (show label when possible).
Section 16. Other Information
This document is believed to be correct, but does not purport to be all inclusive and shall be used only as a guide. Neogen
Corporation shall not be held liable for any damage resulting from handling or from contact with the above product. These
suggestions should not be confused with state, municipal or insurance requirements, and constitute NO WARRANTY.
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Rev New, 04/07
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