Material Safety Data Sheet
1,2,4-Trichlorobenzene (348)
Version 1 Revision Date 02/21/2008 Print Date 02/21/2008
SECTION 1. PRODUCT AND COMPANY IDENTIFICATION
Product name : 1,2,4-Trichlorobenzene
MSDS Number : 000000011217
Product Use Description : Solvent
Company : Honeywell International Inc.
1953 South Harvey Street
Muskegon, MI 49442
For more information call : 1-800-368-0050
(Monday-Friday, 9:00am-5:00pm)
In case of emergency call : Medical: 1-800-498-5701
Transportation: 1-800-424-9300 or 703-527-3887
:
: (24 hours/day, 7 days/week)
SECTION 2. HAZARDS IDENTIFICATION
Emergency Overview
Form : liquid, clear
Color : colourless
Odor : aromatic
Hazard Summary : Harmful by inhalation. May be harmful if swallowed. Irritating to
eyes, respiratory system and skin. May cause irritation of the
gastrointestinal tract. Repeated exposure may cause skin
dryness or cracking. Do not swallow. Avoid breathing vapors,
mist or gas. Avoid contact with skin, eyes and clothing.
Potential Health Effects
Skin : Irritating to skin.
May cause burns or external ulcers.
Prolonged or repeated skin contact with liquid may cause
defatting resulting in drying, redness and possible blistering.
Eyes : Irritating to eyes.
Causes itching, burning, redness and tearing.
Ingestion : May be harmful if swallowed.
Ingestion may cause gastrointestinal irritation, nausea,
vomiting and diarrhoea.
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Material Safety Data Sheet
1,2,4-Trichlorobenzene (348)
Version 1 Revision Date 02/21/2008 Print Date 02/21/2008
Inhalation : Harmful by inhalation.
Irritating to respiratory system.
Chronic Exposure : Prolonged or repeated skin contact with liquid may cause
defatting resulting in drying, redness and possible blistering.
Repeated or prolonged exposure to the substance can produce
liver damage.
Repeated or prolonged exposure to the substance can produce
kidney damage.
Aggravated Medical : Skin disorders
Condition Liver disorders
Kidney disorders
Respiratory disorders
Target Organs : Skin
Eyes
Respiratory system
Liver
Kidney
Carcinogenicity
No component of this product present at levels greater than or equal to 0.1% is identified as a known or
anticipated carcinogen by NTP, IARC, or OSHA.
SECTION 3. COMPOSITION/INFORMATION ON INGREDIENTS
Component CAS-No. Weight %
1,2,4-Trichlorobenzene 120-82-1 98.00
1,3,5-Trichlorobenzene 108-70-3 <2.00
1,2,3-Trichlorobenzene 87-61-6 <2.00
SECTION 4. FIRST AID MEASURES
Inhalation : Remove to fresh air. If not breathing, give artificial respiration. If
breathing is difficult, give oxygen. Use oxygen as required,
provided a qualified operator is present. Call a physician.
Skin contact : Wash off immediately with plenty of water for at least 15
minutes. Take off contaminated clothing and shoes immediately.
Wash contaminated clothing before re-use. Call a physician.
Eye contact : Rinse immediately with plenty of water, also under the eyelids,
for at least 15 minutes. Call a physician.
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Material Safety Data Sheet
1,2,4-Trichlorobenzene (348)
Version 1 Revision Date 02/21/2008 Print Date 02/21/2008
Ingestion : Do not induce vomiting without medical advice. Never give
anything by mouth to an unconscious person. Call a physician.
Notes to physician
Treatment : Treat symptomatically.
SECTION 5. FIRE-FIGHTING MEASURES
Flash point : 105 掳C (221 掳F)
closed cup
Ignition temperature : 571 掳C (1,060 掳F)
Lower explosion limit : 2.5 %(V)
Upper explosion limit : 6.6 %(V)
Suitable extinguishing : Carbon dioxide (CO2)
media Dry chemical
Foam
Specific hazards during fire : Cool closed containers exposed to fire with water spray.
fighting Do not allow run-off from fire fighting to enter drains or water
courses.
In case of fire hazardous decomposition products may be
produced such as:
Carbon monoxide
Carbon dioxide (CO2)
Gaseous hydrogen chloride (HCl).
Special protective : In the event of fire and/or explosion do not breathe fumes.
equipment for fire-fighters Wear self-contained breathing apparatus and protective suit.
SECTION 6. ACCIDENTAL RELEASE MEASURES
Personal precautions : Immediately evacuate personnel to safe areas.
Keep people away from and upwind of spill/leak.
Wear personal protective equipment. Unprotected persons
must be kept away.
Ensure adequate ventilation.
Remove all sources of ignition.
Do not swallow.
Avoid breathing vapors, mist or gas.
Avoid contact with skin, eyes and clothing.
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Material Safety Data Sheet
1,2,4-Trichlorobenzene (348)
Version 1 Revision Date 02/21/2008 Print Date 02/21/2008
Environmental precautions : Discharge into the environment must be avoided.
Prevent further leakage or spillage if safe to do so.
Do not flush into surface water or sanitary sewer system.
Prevent product from entering drains.
Methods for cleaning up : Ventilate the area.
Contain and collect spillage with non-combustible absorbent
materials, e.g. sand, earth, vermiculite, diatomaceous earth and
place in container for disposal according to local regulations
(see section 13).
SECTION 7. HANDLING AND STORAGE
Handling
Handling : Handle with care.
Wear personal protective equipment.
Use only in well-ventilated areas.
Keep container tightly closed.
Containers which are opened must be carefully resealed and
kept upright to prevent leakage.
Keep away from fire, sparks and heated surfaces.
Do not smoke.
Do not swallow.
Avoid contact with skin, eyes and clothing.
Avoid breathing vapors, mist or gas.
Advice on protection against : Normal measures for preventive fire protection.
fire and explosion
Storage
Requirements for storage : Storage rooms must be properly ventilated.
areas and containers Keep containers tightly closed in a dry, cool and well-ventilated
place.
Containers should be protected against falling down.
Containers which are opened must be carefully resealed and
kept upright to prevent leakage.
Keep away from heat and sources of ignition.
Keep away from direct sunlight.
Store away from incompatible substances.
SECTION 8. EXPOSURE CONTROLS / PERSONAL PROTECTION
Protective measures : Ensure that eyewash stations and safety showers are close to
the workstation location.
Do not swallow.
Avoid breathing vapors, mist or gas.
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Material Safety Data Sheet
1,2,4-Trichlorobenzene (348)
Version 1 Revision Date 02/21/2008 Print Date 02/21/2008
Avoid contact with skin, eyes and clothing.
Engineering measures : Use with local exhaust ventilation.
Prevent vapor buildup by providing adequate ventilation during
and after use.
Eye protection : Do not wear contact lenses.
Wear as appropriate:
Safety glasses with side-shields
If splashes are likely to occur, wear:
Goggles or face shield, giving complete protection to eyes
Hand protection : Solvent-resistant gloves
Gloves must be inspected prior to use.
Replace when worn.
Skin and body protection : Wear as appropriate:
Solvent-resistant apron and boots
If splashes are likely to occur, wear:
Protective suit
Respiratory protection : When workers are facing concentrations above the exposure
limit they must use appropriate certified respirators.
For rescue and maintenance work in storage tanks use
self-contained breathing apparatus.
Use NIOSH approved respiratory protection.
Hygiene measures : Handle in accordance with good industrial hygiene and safety
practice.
When using, do not eat, drink or smoke.
Wash hands before breaks and immediately after handling the
product.
Keep working clothes separately.
Remove and wash contaminated clothing before re-use.
Do not swallow.
Avoid breathing vapors, mist or gas.
Avoid contact with skin, eyes and clothing.
Exposure Guidelines
1,2,4-Trichlorobenzene 120-82-1 ACGIH Ceiling 5 ppm
NIOSH Ceil_Time 5 ppm 40 mg/m3
OSHA Z1A Ceiling 5 ppm 40 mg/m3
US CA OEL Ceiling 5 ppm 40 mg/m3
TX ESL ST ESL 50 ppm 400 ug/m3
TX ESL AN ESL 5 ppm 40 ug/m3
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Material Safety Data Sheet
1,2,4-Trichlorobenzene (348)
Version 1 Revision Date 02/21/2008 Print Date 02/21/2008
SECTION 9. PHYSICAL AND CHEMICAL PROPERTIES
Form : liquid, clear
Color : colourless
Odor : aromatic
Molecular Weight : 181.46 g/mol
pH : not applicable
Melting point/range : 17 掳C (63 掳F)
Boiling point/boiling range : 213.5 掳C (416.3 掳F)
Vapor pressure : 1.33 hPa
at 20 掳C (68 掳F)
Relative vapour density : 6.25
(Air = 1.0)
Density : 1.454 g/cm3
at 20 掳C (68 掳F)
Water solubility : 31.3 mg/l
negligible
Partition coefficient: : log Pow: 4.02
n-octanol/water
SECTION 10. STABILITY AND REACTIVITY
Conditions to avoid : Heat, flames and sparks.
Keep away from direct sunlight.
Protect from extreme heat and cold.
Materials to avoid : Oxidizing agents
Acids
Steam
Hazardous decomposition : In case of fire hazardous decomposition products may be
products produced such as:
Carbon monoxide
Carbon dioxide (CO2)
Gaseous hydrogen chloride (HCl).
Hazardous reactions : Hazardous polymerisation does not occur.
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Material Safety Data Sheet
1,2,4-Trichlorobenzene (348)
Version 1 Revision Date 02/21/2008 Print Date 02/21/2008
Stable under normal conditions.
SECTION 11. TOXICOLOGICAL INFORMATION
Acute oral toxicity : LD50 rat
Dose: 756 mg/kg
Acute oral toxicity : LD50 mouse
Dose: 300 mg/kg
Acute dermal toxicity : LD50 rat
Dose: 6,139 mg/kg
SECTION 12. ECOLOGICAL INFORMATION
Toxicity to fish : flow-through test LC50
Species: Pimephales promelas (fathead minnow)
Dose: 2.990 mg/l
Exposure time: 96 h
Toxicity to fish : LC50
Species: Oncorhynchus mykiss (rainbow trout)
Dose: 1.95 mg/l
Exposure time: 48 h
SECTION 13. DISPOSAL CONSIDERATIONS
Waste Information: Observe all Federal, State, and Local Environmental regulations.
SECTION 14. TRANSPORT INFORMATION
DOT UN-Number : 2321
Proper shipping name : Trichlorobenzenes, liquid
Class 6.1
Packing group III
Hazard Label 6.1
IATA UN Number : 2321
Description of the goods : Trichlorobenzenes, liquid
Class : 6.1
Packaging group : III
Hazard Label : 6.1
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Material Safety Data Sheet
1,2,4-Trichlorobenzene (348)
Version 1 Revision Date 02/21/2008 Print Date 02/21/2008
Packing instruction (cargo : 618
aircraft)
Packing instruction : 611
(passenger aircraft)
Packing instruction : Y611
(passenger aircraft)
IMDG Substance No. : UN 2321
Description of the goods : Trichlorobenzenes, liquid
Class : 6.1
Packaging group : III
Hazard Label : 6.1
EmS Number : F-A
Marine pollutant : yes
SECTION 15. REGULATORY INFORMATION
Inventories
EU. EINECS : On or in compliance with the inventory
US. Toxic Substances : On TSCA Inventory
Control Act
Australia. Industrial : On or in compliance with the inventory
Chemical (Notification and
Assessment) Act
Canada. Canadian : All components of this product are on the Canadian DSL list.
Environmental Protection
Act (CEPA). Domestic
Substances List (DSL).
(Can. Gaz. Part II, Vol. 133)
Japan. Kashin-Hou Law List : On or in compliance with the inventory
Korea. Toxic Chemical : On or in compliance with the inventory
Control Law (TCCL) List
Philippines. The Toxic : On or in compliance with the inventory
Substances and Hazardous
and Nuclear Waste Control
Act
China. Inventory of Existing : On or in compliance with the inventory
Chemical Substances
New Zealand. Inventory of : On or in compliance with the inventory
Chemicals (NZIoC), as
published by ERMA New
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Material Safety Data Sheet
1,2,4-Trichlorobenzene (348)
Version 1 Revision Date 02/21/2008 Print Date 02/21/2008
Zealand
National regulatory information
SARA 313 Components : 1,2,4-Trichlorobenzene 120-82-1
CERCLA Reportable : 100 lbs
Quantity
California Prop. 65 : This product does not contain any chemicals known to State of
California to cause cancer, birth, or any other reproductive
defects.
Massachusetts RTK : 1,2,3-Trichlorobenzene 87-61-6
: 1,2,4-Trichlorobenzene 120-82-1
New Jersey RTK : 1,2,4-Trichlorobenzene 120-82-1
: 1,3,5-Trichlorobenzene 108-70-3
: 1,2,3-Trichlorobenzene 87-61-6
Pennsylvania RTK : 1,2,4-Trichlorobenzene 120-82-1
: 1,3,5-Trichlorobenzene 108-70-3
: 1,2,3-Trichlorobenzene 87-61-6
WHMIS Classification : D1B
D2B
SECTION 16. OTHER INFORMATION
HMIS III NFPA
Health Hazard :- 2
Flammability :- 1
Physical Hazard :-
Instability : 0
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