M.S.D.S. 0561
Material Safety Data Sheet
City University of Hong Kong
MSDS Pyrogallol Solution Alkaline 0561
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PRODUCT INFORMATION
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MSDS Name: Pyrogallol/Pyrogallate Absorption Stable Solution Alkaline
Chinese Name: 碌J脵芦脳么隆A鲁s-f陇T脳么
Synonyms: None known.
Ingredient :
Chemical Name CAS#
Pyrogallol 87-66-1
Potassium Hydroxide 1310-58-3
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RISK SYMBOL
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PHYSICAL DATA
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Physical State: Liquid
Appearance: clear to slightly turbid
City University of Hong Kong 1
The above information is believed to be accurate to the best of our knowledge.
No responsibilities or liabilities are assumed or implied by CITY U for their inaccuracies.
Odor: odorless
pH: 12.0 (0.1 M sol.)
Vapor Pressure: 2.6 mm Hg @ 20 C
Vapor Density: >1.0
Evaporation Rate: Not available.
Viscosity: 3.7 cP
Boiling Point: 271-293掳F
Freezing/Melting Point: 48掳F
Autoignition Temperature: Not available.
Flash Point: Not available.
NFPA Rating: Not published.
Explosion Limits, Lower: Not available. Upper: Not available.
Decomposition Temperature: Not available.
Solubility: Completely soluble in water
Specific Gravity/Density: 1.51
Molecular Formula: Solution
Molecular Weight: 0
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FIRE AND EXPLOSION DATA
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General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or
equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal
decomposition or combustion. Wear appropriate protective clothing to prevent contact with skin and eyes. Wear a
self-contained breathing apparatus (SCBA) to prevent contact with thermal decomposition products. Use
extinguishing media appropriate to the surrounding fire. Substance is noncombustible. Use water with caution and in
flooding amounts. Contact with moisture or water may generate sufficient heat to ignite nearby combustible
materials.
Extinguishing Media:
Substance is noncombustible; use agent most appropriate to extinguish surrounding fire. In case of fire use water
spray, dry chemical, carbon dioxide, or appropriate foam.
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REACTIVITY DATA
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Chemical Stability:
Stable at room temperature in closed containers under normal storage and handling conditions. May discolor on
exposure to air. Air sensitive Light sensitive.
Conditions to Avoid:
Incompatible materials, light, dust generation, exposure to air, acids, metals, excess heat.
Incompatibilities with Other Materials:
Strong oxidizing agents, oxidizing agents, strong reducing agents, strong acids, bases, acid chlorides, potassium
permanganate, acid anhydrides, alkalies, iron salts, antipyrine, iodine, air, camphor, menthol, ammonium hydroxide.
Hazardous Decomposition Products:
The above information is believed to be accurate to the best of our knowledge.
No responsibilities or liabilities are assumed or implied by CITY U for their inaccuracies.
M.S.D.S. 0561
Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, oxides of potassium.
Hazardous Polymerization: Has not been reported
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HEALTH HAZARD DATA
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EMERGENCY OVERVIEW
Appearance: clear to slightly turbid.
Danger! Corrosive. Light sensitive. Air sensitive. Possible risk of irreversible effects. May cause liver and kidney
damage. Causes eye and skin irritation. Causes digestive and respiratory tract irritation. May cause blood
abnormalities. May be harmful if swallowed, inhaled, or absorbed through the skin. Possible sensitizer.
Target Organs: Blood, kidneys, liver, respiratory system, skin.
Potential Health Effects
Eye:
May cause irreversible eye injury. Contact may cause ulceration of the conjunctiva and cornea. Eye damage may be
delayed.
Skin:
Causes severe skin irritation. May cause skin sensitization, an allergic reaction, which becomes evident upon re-
exposure to this material. May be harmful if absorbed through the skin. Contact with skin may cause discoloration
and eczema. May cause skin rash (in milder cases), and cold and clammy skin with cyanosis or pale color.
Ingestion:
Causes gastrointestinal irritation with nausea, vomiting and diarrhea. May cause circulatory system failure. May
cause perforation of the digestive tract. May be harmful if swallowed. May cause systemic effects. Rapidly absorbed
from the gastrointestinal tract. Ingestion may cause weakness, muscular incoordination, fine tremors, loss of
reflexes, convulsions and possible death from circulatory collapse.
Inhalation:
May cause methemoglobinemia, cyanosis, convulsions, tachycardia, dyspnea, and death. Irritation may lead to
chemical pneumonitis and pulmonary edema. Causes severe irritation of upper respiratory tract with coughing,
burns, breathing difficulty, and possible coma. Aspiration may lead to pulmonary edema. May be harmful if inhaled.
May cause systemic effects. May be absorbed through the lungs.
Chronic:
Prolonged or repeated skin contact may cause dermatitis. Prolonged or repeated eye contact may cause
conjunctivitis. May cause liver and kidney damage. Absorption into the body leads to the formation of
methemoglobin which in sufficient concentrations causes cyanosis. Effects may be delayed. Pyrogallol has a
tremendous affinity for oxygen of the blood and may cause death by respiratory failure.
Carcinogenicity:
Pyrogallol - Not listed by ACGIN, IARC, NIOSH, NTP, or OSHA.
Potassium Hydroxide - Not listed by ACGIN, IARC, NIOSH, NTP, or OSHA.
Epidemiology:
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The above information is believed to be accurate to the best of our knowledge.
No responsibilities or liabilities are assumed or implied by CITY U for their inaccuracies.
Subcutaneous, rat: TDLo = 3950 mg/kg/58W-I (Tumorigenic - equivocal tumorigenic agent by RTECS criteria -
Tumorigenic - tumors at site of application).
Teratogenicity:
Oral, rat: TDLo = 3 gm/kg (female 6-15 day(s) after conception) Effects on Embryo or Fetus - fetotoxicity (except
death, e.g., Stunted fetus)
Reproductive Effects:
Oral, rat: TDLo = 3 gm/kg (female 6-15 day(s) after conception) Fertility - post-implantation mortality (e.g. Dead
and/or resorbed implants per total number of implants).; Subcutaneous, rat: TDLo = 5 mg/kg (female 1 day(s) pre-
mating) Maternal Effects - ovaries, fallopian tubes.
Neurotoxicity: No information available.
Mutagenicity:
Micronucleus Test: Intraperitoneal, mouse = 252 mg/kg.; Micronucleus Test: Oral, mouse = 504 mg/kg.;
Cytogenetic Analysis: Intraperitoneal, mouse = 100 umol/kg.; Sister Chromatid Exchange: Hamster, Lung = 25
umol/L.; Cytogenetic Analysis: Hamster, Ovary = 100 mg/L.
Other Studies:
Standard Draize test Administration onto the skin: 2 mg/24H (Severe). Standard Draize Test: Administration into the
eye (rabbit) = 20 mg/24H (Moderate).
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FIRST AID MEASURES
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Eyes:
Get medical aid. Do NOT allow victim to rub or keep eyes closed. Extensive irrigation is required (at least 30
minutes).
Skin:
Get medical aid. Immediately flush skin with plenty of soap and water for at least 15 minutes while removing
contaminated clothing and shoes. Discard contaminated clothing in a manner which limits further exposure.
Ingestion:
Do NOT induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by
mouth to an unconscious person. Get medical aid immediately.
Inhalation:
Remove from exposure to fresh air immediately. If breathing is difficult, give oxygen. Get medical aid. DO NOT use
mouth-to-mouth respiration. If breathing has ceased apply artificial respiration using oxygen and a suitable
mechanical device such as a bag and a mask.
Notes to Physician:
Persons with pre-existing skin disorders or eye problems, or impaired liver, kidney, or respiratory function may be
more susceptible to the effects of this substance. Absorption of this product into the body may cause cyanosis.
Moderate degrees of cyanosis need to be treated only by supportive measures: bed rest and oxygen inhalation. For
methemoglobinemia, administer oxygen alone or with Methylene blue depending on the methemoglobinemia
concentration in the blood.
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PREVENTATIVE MEASURES
The above information is believed to be accurate to the best of our knowledge.
No responsibilities or liabilities are assumed or implied by CITY U for their inaccuracies.
M.S.D.S. 0561
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Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use
adequate ventilation to keep airborne concentrations low.
Personal Protective Equipment
Eyes:
Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection
regulations in 29 CFR 1910.133 or European Standard EN166.
Skin: Wear appropriate protective gloves to prevent skin exposure.
Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators:
A respiratory protection program that meets OSHA's 29 CFR 搂1910.134 and ANSI Z88.2 requirements or European
Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.
Handling:
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Do not get in eyes, on skin,
or on clothing. Keep container tightly closed. Do not ingest or inhale. Use with adequate ventilation. Store protected
from light. Handle under an inert atmosphere. Store protected from air. Discard contaminated shoes.
Storage:
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
Keep away from strong acids. Corrosives area. Do not expose to air. Absorbs oxygen from the air and will darken
upon exposure. Store protected from light. Store under an inert atmosphere.
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ENVIRONMENTAL PROTECTION DATA
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Spills/Leaks:
Absorb spill with inert material, (e.g., Dry sand or earth), then place into a chemical waste container. Neutralize spill
with a weak acid such as vinegar or acetic acid. Avoid runoff into storm sewers and ditches which lead to waterways.
Clean up spills immediately, observing precautions in the Protective Equipment section. Provide ventilation. Place
under an inert atmosphere.
City University of Hong Kong 5
The above information is believed to be accurate to the best of our knowledge.
No responsibilities or liabilities are assumed or implied by CITY U for their inaccuracies.
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