RESORCINOL
Chemwatch Material Safety Data Sheet (REVIEW)
Issue Date: 16-Aug-2006 CHEMWATCH 2876
NC317TCP Version No:1
CD 2007/3 Page 1 of 14
Section 1 - CHEMICAL PRODUCT AND COMPANY IDENTIFICATION
PRODUCT NAME
RESORCINOL
SYNONYMS
C6-H6-O2, C6H4(OH)2, m-benzenediol, m-benzenediol, resorcine, resorcin, dihydroxybenzol,
m-hydroquinone, m-hydroquinone, m-dioxybenzene, m-dioxybenzene, 3-hydroxycyclohexadien-1
-one, 3-hydroxycyclohexadien-1-one, m-hydroxyphenol, m-hydroxyphenol, "1, 3 benzenediol",
"3-hydroxy phenol 1, 3 dihydroxybenzene", "3-hydroxy phenol 1, 3 dihydroxybenzene", "C.I.
76505", "C.I. Developer 4", "C.I. Oxidation base 31", "Developer O", "Developer R",
"Developer RS", "Durafur Developer G", "Fouramine RS Fourrine 79", "Fourrine EW", "Nako
TGG", NCI-C05970, "Pelagol Grey RS"
PROPER SHIPPING NAME
RESORCINOL
PRODUCT USE
Used in manufacture of resorcinol- formaldehyde resins, hair dyes, cosmetics,
pharmaceuticals e.g. bacterial and fungicidal skin ointment. As a rubber tackifier and
ultraviolet absorber in polyolefin plastics. Also used as a cross- linking agent for
neoprene and in the tanning industry. RFL dip formulations for tyre cords; dry bonding
agent for rubber compounding, wood adhesives. Intermediate. Intermediate
SUPPLIER
Company: Quantum Chemicals Pty Ltd
Address:
70 Quantum Close
Dandenong South
Victoria 3175
Telephone: 03 8795 8000
Emergency Tel: 1300 131 001
Fax: 03 8795 8099
HAZARD RATINGS
Flammability
Toxicity
Body Contact
Reactivity
Chronic
SCALE: Min/Nil=0 Low=1 Moderate=2 High=3 Extreme=4
RESORCINOL
Chemwatch Material Safety Data Sheet (REVIEW)
Issue Date: 16-Aug-2006 CHEMWATCH 2876
NC317TCP Version No:1
CD 2007/3 Page 2 of 14
Section 2 - HAZARDS IDENTIFICATION
STATEMENT OF HAZARDOUS NATURE
HAZARDOUS SUBSTANCE. DANGEROUS GOODS. According to the Criteria of NOHSC,
and the ADG Code.
POISONS SCHEDULE
None
RISK SAFETY
Harmful if swallowed. Do not breathe dust.
Irritating to eyes and skin. Avoid contact with eyes.
Very toxic to aquatic organisms. Wear suitable protective clothing.
Inhalation and/or skin contact may produce Use only in well ventilated areas.
health damage*.
Cumulative effects may result following Keep container in a well ventilated place.
exposure*.
May produce discomfort of the respiratory To clean the floor and all objects contaminated
system*. by this material use water.
Limited evidence of a carcinogenic effect*. This material and its container must be disposed
of in a safe way.
* (limited evidence). Keep away from food drink and animal feeding
stuffs.
Take off immediately all contaminated clothing.
In case of contact with eyes rinse with plenty
of water and contact Doctor or Poisons
Information Centre.
If swallowed IMMEDIATELY contact Doctor or
Poisons Information Centre (show this container
or label).
Use appropriate container to avoid environment
contamination.
Avoid release to the environment. Refer to
special instructions/ safety data sheets.
This material and its container must be disposed
of as hazardous waste.
Section 3 - COMPOSITION / INFORMATION ON INGREDIENTS
NAME CAS RN %
resorcinol 108-46-3 >98
Section 4 - FIRST AID MEASURES
SWALLOWED
For advice, contact a Poisons Information Centre or a doctor.
路 IF SWALLOWED, REFER FOR MEDICAL ATTENTION, WHERE POSSIBLE, WITHOUT DELAY.
路 For advice, contact a Poisons Information Centre or a doctor.
RESORCINOL
Chemwatch Material Safety Data Sheet (REVIEW)
Issue Date: 16-Aug-2006 CHEMWATCH 2876
NC317TCP Version No:1
CD 2007/3 Page 3 of 14
Section 4 - FIRST AID MEASURES
Where Medical attention is not immediately available or where the patient is more than 15
minutes from a hospital or unless instructed otherwise:
路 Induce vomiting with fingers down the back of the of the throat, ONLY IF CONSCIOUS.
路 Lean patient forward or place on left side (head-down position if possible) to maintain
open airway and prevent aspiration.
NOTE: Wear a protective glove when inducing vomiting by mechanical means.
路 In the mean time, qualified first-aid personnel should treat the patient following
observation and employing supportive measures as indicated by the patient's condition.
路 If the services of a medical officer or medical doctor are readily available, the
patient should be placed in his/her care and a copy of the MSDS should be provided.
Further action will be the responsibility of the medical specialist.
路 If medical attention is not available on the worksite or surroundings send the patient
to a hospital together with a copy of the MSDS.
EYE
If this product comes in contact with the eyes:
路 Immediately hold eyelids apart and flush the eye continuously with running water.
路 Ensure complete irrigation of the eye by keeping eyelids apart and away from eye and
moving the eyelids by occasionally lifting the upper and lower lids.
路 Continue flushing until advised to stop by the Poisons Information Centre or a doctor,
or for at least 15 minutes.
路 Transport to hospital or doctor without delay.
路 Removal of contact lenses after an eye injury should only be undertaken by skilled
personnel.
SKIN
If skin or hair contact occurs:
路 Immediately flush body and clothes with large amounts of water, using safety shower if
available.
路 Quickly remove all contaminated clothing, including footwear.
路 Wash skin and hair with running water. Continue flushing with water until advised to
stop by the Poisons Information Centre.
路 Transport to hospital, or doctor.
INHALED
路 If fumes or combustion products are inhaled remove from contaminated area.
路 Lay patient down. Keep warm and rested.
路 Prostheses such as false teeth, which may block airway, should be removed, where
possible, prior to initiating first aid procedures.
路 Apply artificial respiration if not breathing, preferably with a demand valve
resuscitator, bag-valve mask device, or pocket mask as trained. Perform CPR if necessary.
路 Transport to hospital, or doctor, without delay.
NOTES TO PHYSICIAN
For acute or short term repeated exposures to phenols/ cresols:
路 Phenol is absorbed rapidly through lungs and skin. [Massive skin contact may result in
collapse and death]*
路 [Ingestion may result in ulceration of upper respiratory tract; perforation of
oesophagus and/or stomach, with attendant complications, may occur. Oesophageal stricture
may occur.]*
路 An initial excitatory phase may present. Convulsions may appear as long as 18 hours
after ingestion. Hypotension and ventricular tachycardia that require vasopressor and
antiarrhythmic therapy, respectively, can occur.
路 Respiratory arrest, ventricular dysrhythmias, seizures and metabolic acidosis may
complicate severe phenol exposures so the initial attention should be directed towards
stabilisation of breathing and circulation with ventilation, intubation, intravenous
lines, fluids and cardiac monitoring as indicated.
路 [Vegetable oils retard absorption; do NOT use paraffin oils or alcohols. Gastric lavage
, with endotracheal intubation, should be repeated until phenol odour is no longer
detectable; follow with vegetable oil. A saline cathartic should then be given.]*
ALTERNATIVELY: Activated charcoal (1g/kg) may be given. A cathartic should be given after
RESORCINOL
Chemwatch Material Safety Data Sheet (REVIEW)
Issue Date: 16-Aug-2006 CHEMWATCH 2876
NC317TCP Version No:1
CD 2007/3 Page 4 of 14
Section 4 - FIRST AID MEASURES
oral activated charcoal.
路 Severe poisoning may require slow intravenous injection of methylene blue to treat
methaemoglobinaemia.
路 [Renal failure may require haemodialysis.]*
路 Most absorbed phenol is biotransformed by the liver to ethereal and glucuronide
sulfates and is eliminated almost completely after 24 hours. [Ellenhorn and Barceloux:
Medical Toxicology] *[Union Carbide]
BIOLOGICAL EXPOSURE INDEX - BEI
These represent the determinants observed in specimens collected from a healthy worker
who has been exposed to the Exposure Standard (ES or TLV):
Determinant Index Sampling Time Comments
1. Total phenol in 250 mg/gm creatinine End of shift B, NS
blood
B: Background levels occur in specimens collected from subjects NOT exposed
NS: Non-specific determinant; also seen in exposure to other materials.
The material may induce methaemoglobinaemia following exposure.
路 Initial attention should be directed at oxygen delivery and assisted ventilation if
necessary. Hyperbaric oxygen has not demonstrated substantial benefits.
路 Hypotension should respond to Trendelenburg's position and intravenous fluids;
otherwise dopamine may be needed.
路 Symptomatic patients with methaemoglobin levels over 30% should receive methylene blue.
(Cyanosis, alone, is not an indication for treatment). The usual dose is 1-2 mg/kg of a
1% solution (10 mg/ml) IV over 50 minutes; repeat, using the same dose, if symptoms of
hypoxia fail to subside within 1 hour.
路 Thorough cleansing of the entire contaminated area of the body, including the scalp and
nails, is of utmost importance.
BIOLOGICAL EXPOSURE INDEX - BEI
These represent the determinants observed in specimens collected from a healthy worker
exposed at the Exposure Standard (ES or TLV):
Determinant Index Sampling Time Comment
1. Methaemoglobin in 1.5% of haemoglobin During or end of shift B, NS, SQ
blood
B: Background levels occur in specimens collected from subjects NOT exposed
NS: Non-specific determinant; also observed after exposure to other materials
SQ: Semi-quantitative determinant - Interpretation may be ambiguous; should be used as a
screening test or confirmatory test.
Section 5 - FIRE FIGHTING MEASURES
EXTINGUISHING MEDIA
路 Water spray or fog.
路 Foam.
路 Dry chemical powder.
路 BCF (where regulations permit).
路 Carbon dioxide.
FIRE FIGHTING
Alert Fire Brigade and tell them location and nature of hazard.
RESORCINOL
Chemwatch Material Safety Data Sheet (REVIEW)
Issue Date: 16-Aug-2006 CHEMWATCH 2876
NC317TCP Version No:1
CD 2007/3 Page 5 of 14
Section 5 - FIRE FIGHTING MEASURES
路 Wear full body protective clothing with breathing apparatus.
路 Prevent, by any means available, spillage from entering drains or water courses.
Cool fire exposed containers with water spray from a protected location.
DO NOT approach containers suspected to be hot.
If safe to do so, remove containers from path of fire.
FIRE/EXPLOSION HAZARD
路 Solid which exhibits difficult combustion or is difficult to ignite.
路 Avoid generating dust, particularly clouds of dust in a confined or unventilated space
as dusts may form an explosive mixture with air, and any source of ignition, i.e.
flame or spark, will cause fire or explosion. Dust clouds generated by the fine
grinding of the solid are a particular hazard; accumulations of fine dust may burn
rapidly and fiercely if ignited.
路 Dry dust can also be charged electrostatically by turbulence, pneumatic transport,
pouring, in exhaust ducts and during transport.
路 Build-up of electrostatic charge may be prevented by bonding and grounding.
路 Powder handling equipment such as dust collectors, dryers and mills may require
additional protection measures such as explosion venting.
路 All movable parts coming in contact with this material should have a speed of less than
1-metre/sec.
Heating may cause expansion or decomposition leading to violent rupture of containers.
Decomposes on heating and produces acrid and toxic fumes of: phenolics.
carbon dioxide (CO2).
carbon monoxide (CO).
FIRE INCOMPATIBILITY
Avoid contamination with oxidising agents i.e. nitrates, oxidising acids, chlorine
bleaches, pool chlorine etc. as ignition may result.
HAZCHEM: 2X
Personal Protective Equipment
Gas tight chemical resistant suit.
Section 6 - ACCIDENTAL RELEASE MEASURES
EMERGENCY PROCEDURES
MINOR SPILLS
路 Clean up all spills immediately.
路 Avoid contact with skin and eyes.
路 Wear protective clothing, gloves, safety glasses and dust respirator.
路 Use dry clean up procedures and avoid generating dust.
路 Sweep up or
路 Vacuum up (consider explosion-proof machines designed to be grounded during storage and
use).
路 Place in clean drum then flush area with water.
MAJOR SPILLS
Clear area of personnel and move upwind.
Alert Fire Brigade and tell them location and nature of hazard.
Pollutant - contain spillage.
路 Wear full body protective clothing with breathing apparatus.
路 Prevent, by any means available, spillage from entering drains or water courses.
Shut off all possible sources of ignition and increase ventilation.
Stop leak if safe to do so.
Use dry clean up procedures and avoid generating dust.
Collect recoverable product into labelled containers for recycling.
Collect residues and seal in labelled drums for disposal.
RESORCINOL
Chemwatch Material Safety Data Sheet (REVIEW)
Issue Date: 16-Aug-2006 CHEMWATCH 2876
NC317TCP Version No:1
CD 2007/3 Page 6 of 14
Section 6 - ACCIDENTAL RELEASE MEASURES
Wash area down with large quantity of water and prevent runoff into drains.
If contamination of drains or waterways occurs, advise emergency services.
PROTECTIVE ACTIONS FOR SPILL
PROTECTIVE ACTION ZONE
half
evacuation
downwind
direction
distance
down wind distance
wind isolation
distance
direction
half
evacuation downwind
INITIAL direction distance
ISOLATION
ZONE
From IERG (Canada/Australia)
Isolation Distance 25 metres
Downwind Protection Distance 250 metres
IERG Number 36
FOOTNOTES
1 PROTECTIVE ACTION ZONE is defined as the area in which people are at risk of harmful exposure. This zone
assumes that random changes in wind direction confines the vapour plume to an area within 30 degrees on
either side of the predominant wind direction, resulting in a crosswind protective action distance equal
to the downwind protective action distance.
2 PROTECTIVE ACTIONS should be initiated to the extent possible, beginning with those closest to the spill
and working away from the site in the downwind direction. Within the protective action zone a level of
vapour concentration may exist resulting in nearly all unprotected persons becoming incapacitated and
unable to take protective action and/or incurring serious or irreversible health effects.
3 INITIAL ISOLATION ZONE is determined as an area, including upwind of the incident, within which a high
probability of localised wind reversal may expose nearly all persons without appropriate protection to
life-threatening concentrations of the material.
4 SMALL SPILLS involve a leaking package of 200 litres (55 US gallons) or less, such as a drum (jerrican or
box with inner containers). Larger packages leaking less than 200 litres and compressed gas leaking from
a small cylinder are also considered "small spills".
LARGE SPILLS involve many small leaking packages or a leaking package of greater than 200 litres, such as
a cargo tank, portable tank or a "one-tonne" compressed gas cylinder.
5 Guide 153 is taken from the US DOT emergency response guide book.
6 IERG information is derived from CANUTEC - Transport Canada.
EMERGENCY RESPONSE PLANNING GUIDELINES (ERPG)
The maximum airborne concentration below which it is believed that nearly all individuals could be exposed
for up to one hour WITHOUT experiencing or developing
life-threatening health effects is:
resorcinol 20 ppm
irreversible or other serious effects or symptoms which could impair an individual's ability to take
protective action is:
resorcinol 20 ppm
other than mild, transient adverse effects without perceiving a clearly defined odour is:
resorcinol 20 ppm
The threshold concentration below which most people will experience no appreciable risk of health effects:
resorcinol 10 ppm
RESORCINOL
Chemwatch Material Safety Data Sheet (REVIEW)
Issue Date: 16-Aug-2006 CHEMWATCH 2876
NC317TCP Version No:1
CD 2007/3 Page 7 of 14
Section 6 - ACCIDENTAL RELEASE MEASURES
American Industrial Hygiene Association (AIHA)
Ingredients considered according to the following cutoffs
Very Toxic (T+) >= 0.1% Toxic (T) >= 3.0%
R50 >= 0.25% Corrosive (C) >= 5.0%
R51 >= 2.5%
else >= 10%
where percentage is percentage of ingredient found in the mixture
Personal Protective Equipment advice is contained in Section 8 of the MSDS.
Section 7 - HANDLING AND STORAGE
PROCEDURE FOR HANDLING
路 Avoid all personal contact, including inhalation.
路 Wear protective clothing when risk of exposure occurs.
路 Use in a well-ventilated area.
路 Prevent concentration in hollows and sumps.
路 DO NOT enter confined spaces until atmosphere has been checked.
路 Avoid smoking, naked lights or ignition sources.
路 Avoid contact with incompatible materials.
路 When handling, DO NOT eat, drink or smoke.
路 Keep containers securely sealed when not in use.
路 Avoid physical damage to containers.
路 Always wash hands with soap and water after handling.
路 Work clothes should be laundered separately.
路 Use good occupational work practice.
路 Observe manufacturer's storing and handling recommendations.
路 Atmosphere should be regularly checked against established exposure standards to
ensure safe working conditions.
SUITABLE CONTAINER
路 Metal can or drum
路 Packaging as recommended by manufacturer.
路 Check all containers are clearly labelled and free from leaks.
Multi-ply paper bag with sealed plastic liner or heavy gauge plastic bag.
NOTE: Bags should be stacked, blocked, interlocked, and limited in height so that they
are stable and secure against sliding or collapse. Check that all containers are clearly
labelled and free from leaks. Packing as recommended by manufacturer.
STORAGE INCOMPATIBILITY
Avoid reaction with oxidising agents.
Avoid strong bases.
Segregate from ferric salts alkalis, acetanilide, albumin, camphor,
menthol, antipyrine and urethane.
STORAGE REQUIREMENTS
路 Keep dry.
路 Store in original containers.
路 Keep containers securely sealed.
路 No smoking, naked lights or ignition sources.
路 Store in a cool, dry, well-ventilated area.
路 Store away from incompatible materials.
路 Protect containers against physical damage.
路 Check regularly for leaks.
路 Observe manufacturer's storing and handling recommendations.
RESORCINOL
Chemwatch Material Safety Data Sheet (REVIEW)
Issue Date: 16-Aug-2006 CHEMWATCH 2876
NC317TCP Version No:1
CD 2007/3 Page 8 of 14
Section 7 - HANDLING AND STORAGE
_____________________________________________________
SAFE STORAGE WITH OTHER CLASSIFIED CHEMICALS
+ X + X 0 +
_____________________________________________________
+: May be stored together
O: May be stored together with specific preventions
X: Must not be stored together
Section 8 - EXPOSURE CONTROLS / PERSONAL PROTECTION
EXPOSURE CONTROLS
Source Material TWA ppm TWA mg/m鲁 STEL ppm STEL mg/m鲁
_________ _________ _____ _____ _____ _____
Australia resorcinol 10 45 20 90
Exposure (Resorcinol)
Standards
MATERIAL DATA
Exposure at or below the recommended TLV-TWA is thought to protect the
worker against the significant risk of irritation, methaemoglobinaemia,
cyanosis, convulsions. This value has been derived following analogy with
phenol or catechol.
PERSONAL PROTECTION
EYE
路 Chemical goggles.
路 Full face shield may be required for supplementary but never for primary protection of
eyes
路 Contact lenses may pose a special hazard; soft contact lenses may absorb and
concentrate irritants. A written policy document, describing the wearing of lens or
restrictions on use, should be created for each workplace or task. This should include a
review of lens absorption and adsorption for the class of chemicals in use and an account
of injury experience. Medical and first-aid personnel should be trained in their removal
and suitable equipment should be readily available. In the event of chemical exposure,
begin eye irrigation immediately and remove contact lens as soon as practicable. Lens
should be removed at the first signs of eye redness or irritation - lens should be
removed in a clean environment only after workers have washed hands thoroughly. [CDC
NIOSH Current Intelligence Bulletin 59].
HANDS/FEET
路 Barrier cream. and Neoprene gloves.
Wear chemical protective gloves, eg. PVC.
Wear safety footwear.
RESORCINOL
Chemwatch Material Safety Data Sheet (REVIEW)
Issue Date: 16-Aug-2006 CHEMWATCH 2876
NC317TCP Version No:1
CD 2007/3 Page 9 of 14
Section 8 - EXPOSURE CONTROLS / PERSONAL PROTECTION
#76a-p()
OTHER
路 Overalls.
路 P.V.C. apron.
路 Barrier cream.
路 Skin cleansing cream.
路 Eye wash unit.
Ensure there is ready access to a safety shower.
RESPIRATOR
Protection Factor Half- Face Respirator Full- Face Respirator Powered Air Respirator
10 x ES A P1 Air- line* -- A PAPR- P1 -
50 x ES Air- line** A P2 A PAPR- P2
100 x ES - A P3 -
Air- line* -
100+ x ES - Air- line** A PAPR- P3
* - Negative pressure demand ** - Continuous flow.
The local concentration of material, quantity and conditions of use determine the type of
personal protective equipment required.
For further information consult site specific
CHEMWATCH data (if available), or your
Occupational Health and Safety Advisor.
ENGINEERING CONTROLS
General exhaust is adequate under normal operating conditions. Local exhaust ventilation
may be required in specific circumstances. If risk of overexposure exists, wear approved
respirator. Correct fit is essential to obtain adequate protection. Provide adequate
ventilation in warehouse or closed storage areas. Air contaminants generated in the
workplace possess varying "escape" velocities which, in turn, determine the "capture
velocities" of fresh circulating air required to effectively remove the contaminant.
Type of Contaminant: Air Speed:
solvent, vapours, degreasing etc., evaporating 0.25- 0.5 m/s (50- 100 f/min)
from tank (in still air).
aerosols, fumes from pouring operations, 0.5- 1 m/s (100- 200 f/min.)
intermittent container filling, low speed
conveyer transfers, welding, spray drift,
plating acid fumes, pickling (released at low
velocity into zone of active generation)
direct spray, spray painting in shallow booths, 1- 2.5 m/s (200- 500 f/min.)
drum filling, conveyer loading, crusher dusts,
gas discharge (active generation into zone of
rapid air motion)
grinding, abrasive blasting, tumbling, high 2.5- 10 m/s (500- 2000 f/min.)
speed wheel generated dusts (released at high
initial velocity into zone of very high rapid
air motion).
Within each range the appropriate value depends on:
Lower end of the range Upper end of the range
1: Room air currents minimal or favourable to 1: Disturbing room air currents
capture
2: Contaminants of low toxicity or of nuisance 2: Contaminants of high toxicity
value only.
RESORCINOL
Chemwatch Material Safety Data Sheet (REVIEW)
Issue Date: 16-Aug-2006 CHEMWATCH 2876
NC317TCP Version No:1
CD 2007/3 Page 10 of 14
Section 8 - EXPOSURE CONTROLS / PERSONAL PROTECTION
3: Intermittent, low production. 3: High production, heavy use
4: Large hood or large air mass in motion 4: Small hood- local control only
Simple theory shows that air velocity falls rapidly with distance away from the opening
of a simple extraction pipe. Velocity generally decreases with the square of distance
from the extraction point (in simple cases). Therefore the air speed at the extraction
point should be adjusted, accordingly, after reference to distance from the contaminating
source. The air velocity at the extraction fan, for example, should be a minimum of 1-2
m/s (200-400 f/min) for extraction of solvents generated in a tank 2 meters distant from
the extraction point. Other mechanical considerations, producing performance deficits
within the extraction apparatus, make it essential that theoretical air velocities are
multiplied by factors of 10 or more when extraction systems are installed or used.
Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
APPEARANCE
White needle- like crystals, soluble in water. Faint characteristic odour. Crystals turn
pink on exposure to air and light when impure, and on contact with iron. Solution is
weakly acid, mild antiseptic. Resorcinol is a coke byproduct and a component of cigarette
smoke.
PHYSICAL PROPERTIES
Solid.
Mixes with water.
Molecular Weight: 110.11 Boiling Range (掳C): 280 (sublimes)
Melting Range (掳C): 110 Specific Gravity (water=1): 1.27
Solubility in water (g/L): Miscible pH (as supplied): Not applicable
pH (1% solution): 5.2 concentrate Vapour Pressure (kPa): 0.13 @ 108.4 C
Volatile Component (%vol): 100 Evaporation Rate: Not available
Relative Vapour Density (air=1): 3.8 Flash Point (掳C): 127
Lower Explosive Limit (%): 1.4 @ 200 C Upper Explosive Limit (%): Not available
Autoignition Temp (掳C): 608 Decomposition Temp (掳C): Not Available
State: Divided solid Viscosity: Not Applicable
log Kow (Sangster 1997): 61%
Section 10 - CHEMICAL STABILITY AND REACTIVITY INFORMATION
CONDITIONS CONTRIBUTING TO INSTABILITY
路 Presence of incompatible materials.
路 Product is considered stable.
路 Hazardous polymerisation will not occur.
Section 11 - TOXICOLOGICAL INFORMATION
POTENTIAL HEALTH EFFECTS
ACUTE HEALTH EFFECTS
SWALLOWED
The material is.
capable of causing burns to mouth, throat, oesophagus, with extreme
discomfort, pain and may be fatal if swallowed Ingestion may result in nausea, abdominal
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Section 11 - TOXICOLOGICAL INFORMATION
irritation, pain and vomiting.
The substance and/or its metabolites may bind to haemoglobin inhibiting normal uptake of
oxygen. This condition, known as "methaemoglobinemia", is a form of oxygen starvation
(anoxia).
Symptoms include cyanosis (a bluish discolouration skin and mucous membranes) and
breathing difficulties. Symptoms may not be evident until several hours after exposure.
At about 15% concentration of blood methaemoglobin there is observable cyanosis of the
lips, nose and earlobes. Symptoms may be absent although euphoria, flushed face and
headache are commonly experienced. At 25-40%, cyanosis is marked but little disability
occurs other than that produced on physical exertion. At 40-60%, symptoms include
weakness, dizziness, lightheadedness, increasingly severe headache, ataxia, rapid shallow
respiration, drowsiness, nausea, vomiting, confusion, lethargy and stupor. Above 60%
symptoms include dyspnea, respiratory depression, tachycardia or bradycardia, and
convulsions. Levels exceeding 70% may be fatal.
Some phenol derivatives can cause damage to the digestive system. If absorbed, profuse
sweating, thirst, nausea, vomiting, diarrhoea, cyanosis, restlessness, stupor, low blood
pressure, gasping, abdominal pain, anaemia, convulsions, coma and lung swelling can
happen followed by pneumonia. There may be respiratory failure and kidney damage.
Chemical burns, seizures and irregular heartbeat may result.
EYE
The material is highly discomforting to the eyes and is capable of causing pain and
severe conjunctivitis. Corneal injury may develop, with possible permanent impairment of
vision, if not promptly and adequately treated.
The material may produce severe irritation to the eye causing pronounced inflammation.
Repeated or prolonged exposure to irritants may produce conjunctivitis.
Some phenol derivatives may produce mild to severe eye irritation with redness, pain and
blurred vision. Permanent eye injury may occur; recovery may also be complete or partial.
SKIN
The material is highly discomforting to the skin.
Prolonged exposure may cause chemical burns.
Toxic effects may result from skin absorption.
The material may cause skin irritation after prolonged or repeated exposure and may
produce on contact skin redness, swelling, the production of vesicles, scaling and
thickening of the skin.
Phenol and its derivatives can cause severe skin irritation if contact is maintained, and
can be absorbed to the skin affecting the cardiovascular and central nervous system.
Effects include sweating, intense thirst, nausea and vomiting, diarrhoea, cyanosis,
restlessness, stupor, low blood pressure, hyperventilation, abdominal pain, anaemia,
convulsions, coma, lung swelling followed by pneumonia. Respiratory failure and kidney
damage may follow.
INHALED
The dust may be discomforting to the upper respiratory tract and may be harmful if
inhaled.
Persons with impaired respiratory function, airway diseases and conditions such as
emphysema or chronic bronchitis, may incur further disability if excessive concentrations
of particulate are inhaled.
The vapour from heated material is. discomforting and toxic and the material may present
a hazard from a single acute exposure or from repeated exposures over long periods.
If phenols are absorbed via the lungs, systemic effects may occur affecting the
cardiovascular and nervous systems. Inhalation can result in profuse perspiration,
intense thirst, nausea, vomiting, diarrhoea, cyanosis, restlessness, stupor, falling
blood pressure, hyperventilation, abdominal pain, anaemia, convulsions, coma, swelling
and inflammation of the lung. This is followed by respiratory failure and kidney damage.
Phenols also cause loss of sensation and general depression at high concentrations. The
toxicities of phenol derivatives vary.
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Section 11 - TOXICOLOGICAL INFORMATION
CHRONIC HEALTH EFFECTS
Principal routes of exposure are usually by.
skin contact/absorption.
inhalation of generated dust and inhalation of vapour from heated material.
Long-term exposure to phenol derivatives can cause skin inflammation, loss of appetite
and weight, weakness, muscle aches and pain, liver damage, dark urine, loss of nails,
skin eruptions, diarrhoea, nervous disorders with headache, salivation, fainting,
discolouration of the skin and eyes, vertigo and mental disorders, and damage to the
liver and kidneys.
TOXICITY AND IRRITATION
unless otherwise specified data extracted from RTECS - Register of Toxic Effects of Chemical Substances.
TOXICITY IRRITATION
Oral (human) LDLo: 29 mg/kg Skin (rabbit): 20 mg/24h Moderate
Oral (rat) LD50: 301 mg/kg Eye (rabbit): 100 mg SEVERE
Dermal (rabbit) LD50: 3360 mg/kg
The substance is classified by IARC as Group 3:
NOT classifiable as to its carcinogenicity to humans.
Evidence of carcinogenicity may be inadequate or limited in animal testing.
MATERIAL CARCINOGEN REPROTOXIN SENSITISER SKIN
_______________ ____________ __________ __________ __________
resorcinol IARC:3
CARCINOGEN
IARC: International Agency for Research on Cancer (IARC) Carcinogens: resorcinol
Category: 3
Section 12 - ECOLOGICAL INFORMATION
Fish LC50 (96hr.) (mg/l): 42- 53.4
Daphnia magna EC50 (48hr.) (mg/l): 0.8
log Kow (Sangster 1997): 61%
log Pow (Verschueren 1983): 0.77/0.80
BOD5: 1.15 (61%)
COD: 100%
ThOD: 1.89
log Kow: 0.77-0.8
Koc: 2-65
BOD 5 i61% ThOD
COD: 100% ThOD
ThOD: 1.89
Biodegradation: Adpated culture/ 89% removal after 48 h incubation, feed 446
mg/l
Toxicity Fish: LC50(96)0.44mg/l
Toxicity invertebrate: LC100(24) prtz 6.19mmol/L
Bioacculmulation: low if any
Nitrif. inhib.: 85% inhib at 100mg/L
Anaerobic effects: sig degrad
Effects on algae and plankton: LD0 algae 140mg/L
Ecotoxicity:
Fish LC50 (96 h): 53 mg/l
Daphnia LD0: 0.8 mg/l
Grass shrimp LC50 (96 h): 42 mg/l
Algae (Scenedesmus LD0: 60 mg/l
E. coli LD0: <1000 mg/l
RESORCINOL
Chemwatch Material Safety Data Sheet (REVIEW)
Issue Date: 16-Aug-2006 CHEMWATCH 2876
NC317TCP Version No:1
CD 2007/3 Page 13 of 14
Section 13 - DISPOSAL CONSIDERATIONS
路 Consult manufacturer for recycling options and recycle where possible .
路 Consult State Land Waste Management Authority for disposal.
路 Incinerate residue at an approved site.
路 Recycle containers if possible, or dispose of in an authorised landfill.
Section 14 - TRANSPORTATION INFORMATION
Labels Required: TOXIC
HAZCHEM: 2X
UNDG:
Dangerous Goods Class: 6.1 Subrisk: None
UN Number: 2876 Packing Group: III
Shipping Name:RESORCINOL
Air Transport IATA:
ICAO/IATA Class: 6.1 ICAO/IATA Subrisk: None
UN/ID Number: 2876 Packing Group: III
Special provisions: None
Shipping Name: RESORCINOL
Maritime Transport IMDG:
IMDG Class: 6.1 IMDG Subrisk: None
UN Number: 2876 Packing Group: III
EMS Number: F- A, S- A Special provisions: None
Shipping Name: RESORCINOL
Section 15 - REGULATORY INFORMATION
POISONS SCHEDULE: None
REGULATIONS
resorcinol (CAS: 108-46-3) is found on the following regulatory lists;
Australia Exposure Standards
Australia Inventory of Chemical Substances (AICS)
Australia Standard for the Uniform Scheduling of Drugs and Poisons (SUSDP) - Appendix E (Part 2)
Australia Standard for the Uniform Scheduling of Drugs and Poisons (SUSDP) - Appendix F (Part 3)
Australia Standard for the Uniform Scheduling of Drugs and Poisons (SUSDP) - Schedule 6
International Agency for Research on Cancer (IARC) Carcinogens
International Council of Chemical Associations (ICCA) - High Production Volume List
OECD Representative List of High Production Volume (HPV) Chemicals
Section 16 - OTHER INFORMATION
Classification of the preparation and its individual components has drawn on official and
authoritative sources as well as independent review by the Chemwatch Classification
committee using available literature references.
RESORCINOL
Chemwatch Material Safety Data Sheet (REVIEW)
Issue Date: 16-Aug-2006 CHEMWATCH 2876
NC317TCP Version No:1
CD 2007/3 Page 14 of 14
Section 16 - OTHER INFORMATION
This document is copyright. Apart from any fair dealing for the purposes of private study, research, review or
criticism, as permitted under the Copyright Act, no part may be reproduced by any process without written permission
from CHEMWATCH. TEL (+61 3) 9572 4700.
Issue Date: 16-Aug-2006
Print Date: 4-Jan-2008
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