SULFAMIC ACID
Chemwatch Material Safety Data Sheet (REVIEW)
Issue Date: 24-Jan-2007 CHEMWATCH 2967
NC317TCP Version No:4
CD 2007/3 Page 1 of 13
Section 1 - CHEMICAL PRODUCT AND COMPANY IDENTIFICATION
PRODUCT NAME
SULFAMIC ACID
SYNONYMS
H3-N-O3-S, H3-N-O3-S, NH2-SO3-H, NH2-SO2-OH, Sigma, Redox, "Hach Sulfamic Acid Reagent",
"amidosulphonic acid", "amidosulphuric acid", "aminosulphonic acid", "aminosulphuric
acid", "sulphamidic acid", "sulphamic acid, solid", "amidosulfonic acid", "amidosulfuric
acid", "aminosulfonic acid", "aminosulfuric acid", "sulfamidic acid", "sulfamidic acid,
solid"
PROPER SHIPPING NAME
SULPHAMIC ACID
PRODUCT USE
Used for cleaning metals and ceramics; standard in alkalimetry; nitrite removal in dyeing;
stabilisation of chlorine and hypochlorite for swimming pools; sulfonating agent; organic
synthesis; pH control; hard water scale removal; electroplating. Laboratory reagent.
SUPPLIER
Company: Quantum Chemicals Pty Ltd
Address:
70 Quantum Close
Dandenong South
Victoria 3175
Telephone: 03 8795 8000
Emergency Tel: 1300 131 001
Fax: 03 8795 8099
HAZARD RATINGS
Flammability
Toxicity
Body Contact
Reactivity
Chronic
SCALE: Min/Nil=0 Low=1 Moderate=2 High=3 Extreme=4
SULFAMIC ACID
Chemwatch Material Safety Data Sheet (REVIEW)
Issue Date: 24-Jan-2007 CHEMWATCH 2967
NC317TCP Version No:4
CD 2007/3 Page 2 of 13
Section 2 - HAZARDS IDENTIFICATION
STATEMENT OF HAZARDOUS NATURE
HAZARDOUS SUBSTANCE. DANGEROUS GOODS. According to the Criteria of NOHSC,
and the ADG Code.
POISONS SCHEDULE
S6
RISK SAFETY
Irritating to eyes respiratory system and skin. Do not breathe dust.
Harmful to aquatic organisms may cause long- Avoid contact with skin.
term adverse effects in the aquatic environment.
Cumulative effects may result following Wear eye/ face protection.
exposure*.
Eye contact may produce serious damage*. To clean the floor and all objects contaminated
by this material use water.
* (limited evidence). In case of contact with eyes rinse with plenty
of water and contact Doctor or Poisons
Information Centre.
If swallowed IMMEDIATELY contact Doctor or
Poisons Information Centre (show this container
or label).
This material and its container must be disposed
of as hazardous waste.
Section 3 - COMPOSITION / INFORMATION ON INGREDIENTS
NAME CAS RN %
sulfamic acid 5329-14-6 >98
Section 4 - FIRST AID MEASURES
SWALLOWED
路 For advice, contact a Poisons Information Centre or a doctor at once.
路 Urgent hospital treatment is likely to be needed.
路 If swallowed do NOT induce vomiting.
路 If vomiting occurs, lean patient forward or place on left side (head-down position, if
possible) to maintain open airway and prevent aspiration.
路 Observe the patient carefully.
路 Never give liquid to a person showing signs of being sleepy or with reduced awareness;
i.e. becoming unconscious.
路 Give water to rinse out mouth, then provide liquid slowly and as much as casualty can
comfortably drink.
路 Transport to hospital or doctor without delay.
EYE
If this product comes in contact with the eyes:
SULFAMIC ACID
Chemwatch Material Safety Data Sheet (REVIEW)
Issue Date: 24-Jan-2007 CHEMWATCH 2967
NC317TCP Version No:4
CD 2007/3 Page 3 of 13
Section 4 - FIRST AID MEASURES
路 Immediately hold eyelids apart and flush the eye continuously with running water.
路 Ensure complete irrigation of the eye by keeping eyelids apart and away from eye and
moving the eyelids by occasionally lifting the upper and lower lids.
路 Continue flushing until advised to stop by the Poisons Information Centre or a doctor,
or for at least 15 minutes.
路 Transport to hospital or doctor without delay.
路 Removal of contact lenses after an eye injury should only be undertaken by skilled
personnel.
SKIN
If skin or hair contact occurs:
路 Immediately flush body and clothes with large amounts of water, using safety shower if
available.
路 Quickly remove all contaminated clothing, including footwear.
路 Wash skin and hair with running water. Continue flushing with water until advised to
stop by the Poisons Information Centre.
路 Transport to hospital, or doctor.
INHALED
路 If fumes or combustion products are inhaled remove from contaminated area.
路 Lay patient down. Keep warm and rested.
路 Prostheses such as false teeth, which may block airway, should be removed, where
possible, prior to initiating first aid procedures.
路 Apply artificial respiration if not breathing, preferably with a demand valve
resuscitator, bag-valve mask device, or pocket mask as trained. Perform CPR if necessary.
路 Transport to hospital, or doctor, without delay.
NOTES TO PHYSICIAN
Treat symptomatically.
For acute or short term repeated exposures to strong acids:
路 Airway problems may arise from laryngeal edema and inhalation exposure. Treat with 100%
oxygen initially.
路 Respiratory distress may require cricothyroidotomy if endotracheal intubation is
contraindicated by excessive swelling
路 Intravenous lines should be established immediately in all cases where there is
evidence of circulatory compromise.
路 Strong acids produce a coagulation necrosis characterised by formation of a coagulum
(eschar) as a result of the dessicating action of the acid on proteins in specific
tissues.
INGESTION:
路 Immediate dilution (milk or water) within 30 minutes post ingestion is recommended.
路 DO NOT attempt to neutralise the acid since exothermic reaction may extend the
corrosive injury.
路 Be careful to avoid further vomit since re-exposure of the mucosa to the acid is
harmful. Limit fluids to one or two glasses in an adult.
路 Charcoal has no place in acid management.
路 Some authors suggest the use of lavage within 1 hour of ingestion.
SKIN:
路 Skin lesions require copious saline irrigation. Treat chemical burns as thermal burns
with non-adherent gauze and wrapping.
路 Deep second-degree burns may benefit from topical silver sulfadiazine.
EYE:
路 Eye injuries require retraction of the eyelids to ensure thorough irrigation of the
conjuctival cul-de-sacs. Irrigation should last at least 20-30 minutes. DO NOT use
neutralising agents or any other additives. Several litres of saline are required.
路 Cycloplegic drops, (1% cyclopentolate for short-term use or 5% homatropine for longer
term use) antibiotic drops, vasoconstrictive agents or artificial tears may be indicated
dependent on the severity of the injury.
路 Steroid eye drops should only be administered with the approval of a consulting
ophthalmologist).
SULFAMIC ACID
Chemwatch Material Safety Data Sheet (REVIEW)
Issue Date: 24-Jan-2007 CHEMWATCH 2967
NC317TCP Version No:4
CD 2007/3 Page 4 of 13
Section 4 - FIRST AID MEASURES
[Ellenhorn and Barceloux: Medical Toxicology].
Section 5 - FIRE FIGHTING MEASURES
EXTINGUISHING MEDIA
路 Water spray or fog.
路 Foam.
路 Dry chemical powder.
路 BCF (where regulations permit).
路 Carbon dioxide.
FIRE FIGHTING
路 Alert Fire Brigade and tell them location and nature of hazard.
路 Wear breathing apparatus plus protective gloves.
路 Prevent, by any means available, spillage from entering drains or water courses.
路 Use fire fighting procedures suitable for surrounding area.
路 DO NOT approach containers suspected to be hot.
路 Cool fire exposed containers with water spray from a protected location.
路 If safe to do so, remove containers from path of fire.
路 Equipment should be thoroughly decontaminated after use.
FIRE/EXPLOSION HAZARD
路 Non combustible.
路 Not considered to be a significant fire risk.
路 Acids may react with metals to produce hydrogen, a highly flammable and explosive gas.
路 Heating may cause expansion or decomposition leading to violent rupture of containers.
路 May emit corrosive, poisonous fumes. May emit acrid smoke.
Decomposition may produce toxic fumes of: nitrogen oxides (NOx), sulfur oxides (SOx),
hydrogen chloride.
FIRE INCOMPATIBILITY
None known.
HAZCHEM: 2Z
Section 6 - ACCIDENTAL RELEASE MEASURES
EMERGENCY PROCEDURES
MINOR SPILLS
路 Clean up all spills immediately.
路 Avoid contact with skin and eyes.
路 Wear protective clothing, gloves, safety glasses and dust respirator.
路 Use dry clean up procedures and avoid generating dust.
路 Sweep up or
路 Vacuum up (consider explosion-proof machines designed to be grounded during storage and
use).
路 Place in clean drum then flush area with water.
MAJOR SPILLS
路 Clear area of personnel and move upwind.
路 Alert Fire Brigade and tell them location and nature of hazard.
路 Wear breathing apparatus plus protective gloves.
路 Prevent, by any means available, spillage from entering drains or water course.
路 Stop leak if safe to do so.
路 Contain spill with sand, earth or vermiculite.
路 Collect recoverable product into labelled containers for recycling.
SULFAMIC ACID
Chemwatch Material Safety Data Sheet (REVIEW)
Issue Date: 24-Jan-2007 CHEMWATCH 2967
NC317TCP Version No:4
CD 2007/3 Page 5 of 13
Section 6 - ACCIDENTAL RELEASE MEASURES
路 Neutralise/decontaminate residue.
路 Collect solid residues and seal in labelled drums for disposal.
路 Wash area and prevent runoff into drains.
路 After clean up operations, decontaminate and launder all protective clothing and
equipment before storing and re-using.
路 If contamination of drains or waterways occurs, advise emergency services.
PROTECTIVE ACTIONS FOR SPILL
PROTECTIVE ACTION ZONE
half
evacuation
downwind
direction
distance
down wind distance
wind isolation
distance
direction
half
evacuation downwind
INITIAL direction distance
ISOLATION
ZONE
From IERG (Canada/Australia)
Isolation Distance 25 metres
Downwind Protection Distance 250 metres
IERG Number 37
FOOTNOTES
1 PROTECTIVE ACTION ZONE is defined as the area in which people are at risk of harmful exposure. This zone
assumes that random changes in wind direction confines the vapour plume to an area within 30 degrees on
either side of the predominant wind direction, resulting in a crosswind protective action distance equal
to the downwind protective action distance.
2 PROTECTIVE ACTIONS should be initiated to the extent possible, beginning with those closest to the spill
and working away from the site in the downwind direction. Within the protective action zone a level of
vapour concentration may exist resulting in nearly all unprotected persons becoming incapacitated and
unable to take protective action and/or incurring serious or irreversible health effects.
3 INITIAL ISOLATION ZONE is determined as an area, including upwind of the incident, within which a high
probability of localised wind reversal may expose nearly all persons without appropriate protection to
life-threatening concentrations of the material.
4 SMALL SPILLS involve a leaking package of 200 litres (55 US gallons) or less, such as a drum (jerrican or
box with inner containers). Larger packages leaking less than 200 litres and compressed gas leaking from
a small cylinder are also considered "small spills".
LARGE SPILLS involve many small leaking packages or a leaking package of greater than 200 litres, such as
a cargo tank, portable tank or a "one-tonne" compressed gas cylinder.
5 Guide 154 is taken from the US DOT emergency response guide book.
6 IERG information is derived from CANUTEC - Transport Canada.
EMERGENCY RESPONSE PLANNING GUIDELINES (ERPG)
The maximum airborne concentration below which it is believed that nearly all individuals could be exposed
for up to one hour WITHOUT experiencing or developing
life-threatening health effects is:
sulfamic acid 500 mg/m鲁
irreversible or other serious effects or symptoms which could impair an individual's ability to take
protective action is:
sulfamic acid 250 mg/m鲁
other than mild, transient adverse effects without perceiving a clearly defined odour is:
sulfamic acid 40 mg/m鲁
SULFAMIC ACID
Chemwatch Material Safety Data Sheet (REVIEW)
Issue Date: 24-Jan-2007 CHEMWATCH 2967
NC317TCP Version No:4
CD 2007/3 Page 6 of 13
Section 6 - ACCIDENTAL RELEASE MEASURES
The threshold concentration below which most people will experience no appreciable risk of health effects:
sulfamic acid 12.5 mg/m鲁
American Industrial Hygiene Association (AIHA)
Ingredients considered according to the following cutoffs
Very Toxic (T+) >= 0.1% Toxic (T) >= 3.0%
R50 >= 0.25% Corrosive (C) >= 5.0%
R51 >= 2.5%
else >= 10%
where percentage is percentage of ingredient found in the mixture
Personal Protective Equipment advice is contained in Section 8 of the MSDS.
Section 7 - HANDLING AND STORAGE
PROCEDURE FOR HANDLING
路 Avoid all personal contact, including inhalation.
路 Wear protective clothing when risk of exposure occurs.
路 Use in a well-ventilated area.
路 Avoid contact with moisture.
路 Avoid contact with incompatible materials.
路 When handling, DO NOT eat, drink or smoke.
路 Keep containers securely sealed when not in use.
路 Avoid physical damage to containers.
路 Always wash hands with soap and water after handling.
路 Work clothes should be laundered separately. Launder contaminated clothing before re
-use.
路 Use good occupational work practice.
路 Observe manufacturer's storing and handling recommendations.
路 Atmosphere should be regularly checked against established exposure standards to ensure
safe working conditions are maintained.
SUITABLE CONTAINER
DO NOT use aluminium or galvanised containers.
Glass container.
路 Lined metal can, lined metal pail/ can.
路 Plastic pail.
路 Polyliner drum.
路 Packing as recommended by manufacturer.
路 Check all containers are clearly labelled and free from leaks.
STORAGE INCOMPATIBILITY
Avoid strong acids, bases.
路 Inorganic acids are generally soluble in water with the release of hydrogen ions. The
resulting solutions have pH's of less than 7.0.
路 Inorganic acids neutralise chemical bases (for example: amines and inorganic
hydroxides) to form salts.
路 Neutralisation can generate dangerously large amounts of heat in small spaces.
路 The dissolution of inorganic acids in water or the dilution of their concentrated
solutions with additional water may generate significant heat.
路 The addition of water to inorganic acids often generates sufficient heat in the small
region of mixing to cause some of the water to boil explosively. The resulting "bumping"
can spatter the acid.
路 Inorganic acids react with active metals, including such structural metals as aluminum
and iron, to release hydrogen, a flammable gas.
路 Inorganic acids can initiate the polymerisation of certain classes of organic
SULFAMIC ACID
Chemwatch Material Safety Data Sheet (REVIEW)
Issue Date: 24-Jan-2007 CHEMWATCH 2967
NC317TCP Version No:4
CD 2007/3 Page 7 of 13
Section 7 - HANDLING AND STORAGE
compounds.
路 Inorganic acids react with cyanide compounds to release gaseous hydrogen cyanide.
路 Inorganic acids generate flammable and/or toxic gases in contact with dithiocarbamates,
isocyanates, mercaptans, nitrides, nitriles, sulfides, and strong reducing agents.
Additional gas-generating reactions occur with sulfites, nitrites, thiosulfates (to give
H2S and SO3), dithionites (SO2), and even carbonates.
路 Acids often catalyse (increase the rate of) chemical reactions.
Avoid reaction with hypochlorous acid and sulfides
STORAGE REQUIREMENTS
路 Store in original containers.
路 Keep containers securely sealed.
路 Store in a cool, dry, well-ventilated area.
路 Store away from incompatible materials and foodstuff containers.
路 Protect containers against physical damage and check regularly for leaks.
路 Observe manufacturer's storing and handling recommendations.
_____________________________________________________
SAFE STORAGE WITH OTHER CLASSIFIED CHEMICALS
+ X + X 0 +
_____________________________________________________
+: May be stored together
O: May be stored together with specific preventions
X: Must not be stored together
Section 8 - EXPOSURE CONTROLS / PERSONAL PROTECTION
EXPOSURE CONTROLS
The following materials had no OELs on our records
鈥? sulfamic acid: CAS:5329- 14- 6
MATERIAL DATA
Sensory irritants are chemicals that produce temporary and undesirable side-effects on
the eyes, nose or throat. Historically occupational exposure standards for these
irritants have been based on observation of workers' responses to various airborne
concentrations. Present day expectations require that nearly every individual should be
protected against even minor sensory irritation and exposure standards are established
using uncertainty factors or safety factors of 5 to 10 or more. On occasion animal no
-observable-effect-levels (NOEL) are used to determine these limits where human results
are unavailable. An additional approach, typically used by the TLV committee (USA) in
determining respiratory standards for this group of chemicals, has been to assign ceiling
values (TLV C) to rapidly acting irritants and to assign short-term exposure limits (TLV
STELs) when the weight of evidence from irritation, bioaccumulation and other endpoints
combine to warrant such a limit. In contrast the MAK Commission (Germany) uses a five
-category system based on intensive odour, local irritation, and elimination half-life.
However this system is being replaced to be consistent with the European Union (EU)
Scientific Committee for Occupational Exposure Limits (SCOEL); this is more closely
allied to that of the USA.
OSHA (USA) concluded that exposure to sensory irritants can:
路 cause inflammation
路 cause increased susceptibility to other irritants and infectious agents
路 lead to permanent injury or dysfunction
路 permit greater absorption of hazardous substances and
路 acclimate the worker to the irritant warning properties of these substances thus
SULFAMIC ACID
Chemwatch Material Safety Data Sheet (REVIEW)
Issue Date: 24-Jan-2007 CHEMWATCH 2967
NC317TCP Version No:4
CD 2007/3 Page 8 of 13
Section 8 - EXPOSURE CONTROLS / PERSONAL PROTECTION
increasing the risk of overexposure.
It is the goal of the ACGIH (and other Agencies) to recommend TLVs (or their equivalent)
for all substances for which there is evidence of health effects at airborne
concentrations encountered in the workplace.
At this time no TLV has been established, even though this material may produce adverse
health effects (as evidenced in animal experiments or clinical experience). Airborne
concentrations must be maintained as low as is practically possible and occupational
exposure must be kept to a minimum.
NOTE: The ACGIH occupational exposure standard for Particles Not Otherwise Specified
(P.N.O.S) does NOT apply.
PERSONAL PROTECTION
EYE
路 Chemical goggles.
路 Full face shield may be required for supplementary but never for primary protection of
eyes
路 Contact lenses may pose a special hazard; soft contact lenses may absorb and
concentrate irritants. A written policy document, describing the wearing of lens or
restrictions on use, should be created for each workplace or task. This should include a
review of lens absorption and adsorption for the class of chemicals in use and an account
of injury experience. Medical and first-aid personnel should be trained in their removal
and suitable equipment should be readily available. In the event of chemical exposure,
begin eye irrigation immediately and remove contact lens as soon as practicable. Lens
should be removed at the first signs of eye redness or irritation - lens should be
removed in a clean environment only after workers have washed hands thoroughly. [CDC
NIOSH Current Intelligence Bulletin 59].
HANDS/FEET
Suitability and durability of glove type is dependent on usage. Factors such as:
路 frequency and duration of contact,
路 chemical resistance of glove material,
路 glove thickness and
路 dexterity,
are important in the selection of gloves.
Elbow length PVC gloves.
OTHER
路 Overalls.
路 PVC Apron.
路 PVC protective suit may be required if exposure severe.
路 Eyewash unit.
路 Ensure there is ready access to a safety shower.
RESPIRATOR
Protection Factor Half- Face Respirator Full- Face Respirator Powered Air Respirator
10 x ES P1 Air- line* -- PAPR- P1 -
50 x ES Air- line** P2 PAPR- P2
100 x ES - P3 -
Air- line* -
100+ x ES - Air- line** PAPR- P3
* - Negative pressure demand ** - Continuous flow.
SULFAMIC ACID
Chemwatch Material Safety Data Sheet (REVIEW)
Issue Date: 24-Jan-2007 CHEMWATCH 2967
NC317TCP Version No:4
CD 2007/3 Page 9 of 13
Section 8 - EXPOSURE CONTROLS / PERSONAL PROTECTION
The local concentration of material, quantity and conditions of use determine the type of
personal protective equipment required.
For further information consult site specific
CHEMWATCH data (if available), or your
Occupational Health and Safety Advisor.
ENGINEERING CONTROLS
Local exhaust ventilation usually required. If risk of overexposure exists, wear approved
respirator. Correct fit is essential to obtain adequate protection. Supplied-air type
respirator may be required in special circumstances. Correct fit is essential to ensure
adequate protection.
An approved self contained breathing apparatus (SCBA) may be required in some situations.
Provide adequate ventilation in warehouse or closed storage area. Air contaminants
generated in the workplace possess varying "escape" velocities which, in turn, determine
the "capture velocities" of fresh circulating air required to effectively remove the
contaminant.
Type of Contaminant: Air Speed:
solvent, vapours, degreasing etc., evaporating 0.25- 0.5 m/s (50- 100 f/min.)
from tank (in still air).
aerosols, fumes from pouring operations, 0.5- 1 m/s (100- 200 f/min.)
intermittent container filling, low speed
conveyer transfers, welding, spray drift,
plating acid fumes, pickling (released at low
velocity into zone of active generation)
direct spray, spray painting in shallow booths, 1- 2.5 m/s (200- 500 f/min.)
drum filling, conveyer loading, crusher dusts,
gas discharge (active generation into zone of
rapid air motion)
grinding, abrasive blasting, tumbling, high 2.5- 10 m/s (500- 2000 f/min.)
speed wheel generated dusts (released at high
initial velocity into zone of very high rapid
air motion).
Within each range the appropriate value depends on:
Lower end of the range Upper end of the range
1: Room air currents minimal or favourable to 1: Disturbing room air currents
capture
2: Contaminants of low toxicity or of nuisance 2: Contaminants of high toxicity
value only.
3: Intermittent, low production. 3: High production, heavy use
4: Large hood or large air mass in motion 4: Small hood- local control only
Simple theory shows that air velocity falls rapidly with distance away from the opening
of a simple extraction pipe. Velocity generally decreases with the square of distance
from the extraction point (in simple cases). Therefore the air speed at the extraction
point should be adjusted, accordingly, after reference to distance from the contaminating
source. The air velocity at the extraction fan, for example, should be a minimum of 1-2
m/s (200-400 f/min) for extraction of solvents generated in a tank 2 meters distant from
the extraction point. Other mechanical considerations, producing performance deficits
within the extraction apparatus, make it essential that theoretical air velocities are
multiplied by factors of 10 or more when extraction systems are installed or used.
SULFAMIC ACID
Chemwatch Material Safety Data Sheet (REVIEW)
Issue Date: 24-Jan-2007 CHEMWATCH 2967
NC317TCP Version No:4
CD 2007/3 Page 10 of 13
Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
APPEARANCE
White crystalline (or brownish grey for technical grades), odourless solid. Non-
hygroscopic. Soluble in water giving highly acid solutions.
PHYSICAL PROPERTIES
Solid.
Mixes with water.
Corrosive.
Acid.
Molecular Weight: 97.10 Boiling Range (掳C): Decomposes @ 205
Melting Range (掳C): 200- 205 Specific Gravity (water=1): 2.15
Solubility in water (g/L): Miscible pH (as supplied): Not applicable
pH (1% solution): 1.2 Vapour Pressure (kPa): Not applicable
Volatile Component (%vol): Nil Evaporation Rate: Not applicable
Relative Vapour Density (air=1): Not applicable Flash Point (掳C): Not applicable
Lower Explosive Limit (%): Not applicable Upper Explosive Limit (%): Not applicable
Autoignition Temp (掳C): Not available. Decomposition Temp (掳C): Not Available
State: Divided solid Viscosity: Not Applicable
Section 10 - CHEMICAL STABILITY AND REACTIVITY INFORMATION
CONDITIONS CONTRIBUTING TO INSTABILITY
Contact with alkaline material liberates heat.
路 Presence of incompatible materials.
路 Product is considered stable.
路 Hazardous polymerisation will not occur.
Section 11 - TOXICOLOGICAL INFORMATION
POTENTIAL HEALTH EFFECTS
ACUTE HEALTH EFFECTS
SWALLOWED
Ingestion of acidic corrosives may produce burns around and in the mouth, the throat and
oesophagus. Immediate pain and difficulties in swallowing and speaking may also be
evident. Swelling of the epiglottis may make it difficult to breathe which may result in
suffocation. More severe exposure may result in vomiting blood and thick mucus, shock,
abnormally low blood pressure, fluctuating pulse, shallow respiration and clammy skin,
inflammation of stomach wall, and rupture of oesophageal tissue. Untreated shock may
eventually result in kidney failure. Severe cases may result in perforation of the
stomach and abdominal cavity with consequent infection, rigidity and fever. There may be
severe narrowing of the oesophageal or pyloric sphincters; this may occur immediately or
after a delay of weeks to years. There may be coma and convulsions, followed by death due
to infection of the abdominal cavity, kidneys or lungs.
The material has NOT been classified by EC Directives or other classification systems as
"harmful by ingestion". This is because of the lack of corroborating animal or human
evidence. The material may still be damaging to the health of the individual, following
ingestion, especially where pre-existing organ (eg. liver, kidney) damage is evident.
Present definitions of harmful or toxic substances are generally based on doses producing
mortality rather than those producing morbidity (disease, ill-health). Gastrointestinal
tract discomfort may produce nausea and vomiting. In an occupational setting however,
ingestion of insignificant quantities is not thought to be cause for concern.
SULFAMIC ACID
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Issue Date: 24-Jan-2007 CHEMWATCH 2967
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Section 11 - TOXICOLOGICAL INFORMATION
EYE
If applied to the eyes, this material causes severe eye damage.
Direct eye contact with acid corrosives may produce pain, tears, sensitivity to light and
burns. Mild burns of the epithelia generally recover rapidly and completely. Severe burns
produce long-lasting and possibly irreversible damage. The appearance of the burn may not
be apparent for several weeks after the initial contact. The cornea may ultimately become
deeply opaque resulting in blindness.
SKIN
Skin contact with acidic corrosives may result in pain and burns; these may be deep with
distinct edges and may heal slowly with the formation of scar tissue.
Skin contact is not thought to have harmful health effects (as classified under EC
Directives); the material may still produce health damage following entry through wounds,
lesions or abrasions.
Solution of material in moisture on the skin, or perspiration, may markedly increase skin
corrosion and accelerate tissue destruction.
INHALED
The material can cause respiratory irritation in some persons. The body's response to
such irritation can cause further lung damage.
Corrosive acids can cause irritation of the respiratory tract, with coughing, choking and
mucous membrane damage. There may be dizziness, headache, nausea and weakness. Swelling
of the lungs can occur, either immediately or after a delay; symptoms of this include
chest tightness, shortness of breath, frothy phlegm and cyanosis. Lack of oxygen can
cause death hours after onset.
Persons with impaired respiratory function, airway diseases and conditions such as
emphysema or chronic bronchitis, may incur further disability if excessive concentrations
of particulate are inhaled.
CHRONIC HEALTH EFFECTS
Repeated or prolonged exposure to acids may result in the erosion of teeth, swelling
and/or ulceration of mouth lining. Irritation of airways to lung, with cough, and
inflammation of lung tissue often occurs. Chronic exposure may inflame the skin or
conjunctiva.
Substance accumulation, in the human body, may occur and may cause some concern following
repeated or long-term occupational exposure.
Long term exposure to high dust concentrations may cause changes in lung function i.e.
pneumoconiosis; caused by particles less than 0.5 micron penetrating and remaining in the
lung. Prime symptom is breathlessness; lung shadows show on X-ray.
Long-term exposure to respiratory irritants may result in disease of the airways
involving difficult breathing and related systemic problems.
TOXICITY AND IRRITATION
unless otherwise specified data extracted from RTECS - Register of Toxic Effects of Chemical Substances.
TOXICITY IRRITATION
Oral (rat) LD50: 3160 mg/kg Skin (human): 4 %/5 days (I)- Mild
Skin (rabbit): 500 mg/24 h- SEVERE
Eye (rabbit): 250 ug/24 h - SEVERE
Eye (rabbit): 20 mg - Moderate
The material may produce severe irritation to the eye causing pronounced inflammation.
Repeated or prolonged exposure to irritants may produce conjunctivitis.
The material may cause severe skin irritation after prolonged or repeated exposure and
may produce on contact skin redness, swelling, the production of vesicles, scaling and
thickening of the skin. Repeated exposures may produce severe ulceration.
Asthma-like symptoms may continue for months or even years after exposure to the material
ceases. This may be due to a non-allergenic condition known as reactive airways
dysfunction syndrome (RADS) which can occur following exposure to high levels of highly
irritating compound. Key criteria for the diagnosis of RADS include the absence of
preceding respiratory disease, in a non-atopic individual, with abrupt onset of
persistent asthma-like symptoms within minutes to hours of a documented exposure to the
SULFAMIC ACID
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Section 11 - TOXICOLOGICAL INFORMATION
irritant. A reversible airflow pattern, on spirometry, with the presence of moderate to
severe bronchial hyperreactivity on methacholine challenge testing and the lack of
minimal lymphocytic inflammation, without eosinophilia, have also been included in the
criteria for diagnosis of RADS. RADS (or asthma) following an irritating inhalation is an
infrequent disorder with rates related to the concentration of and duration of exposure
to the irritating substance. Industrial bronchitis, on the other hand, is a disorder that
occurs as result of exposure due to high concentrations of irritating substance (often
particulate in nature) and is completely reversible after exposure ceases. The disorder
is characterised by dyspnea, cough and mucus production.
Section 12 - ECOLOGICAL INFORMATION
Prevent, by any means available, spillage from entering drains or water
courses.
Do NOT allow product to come in contact with surface waters or to intertidal areas below
the mean high water mark. Do not contaminate water when cleaning equipment or disposing
of equipment wash-waters.
Wastes resulting from use of the product must be disposed of on site or at approved waste
sites.
Section 13 - DISPOSAL CONSIDERATIONS
Recycle wherever possible.
路 Consult manufacturer for recycling options or consult local or regional waste
management authority for disposal if no suitable treatment or disposal facility can be
identified.
路 Treat and neutralise at an approved treatment plant. Treatment should involve: Mixing
or slurrying in water; Neutralisation with soda-lime or soda-ash followed by: Burial in a
licenced land-fill or Incineration in a licenced apparatus (after admixture with suitable
combustible material)
路 Decontaminate empty containers with 5% aqueous sodium hydroxide or soda ash, followed
by water. Observe all label safeguards until containers are cleaned and destroyed.
Section 14 - TRANSPORTATION INFORMATION
Labels Required: CORROSIVE
HAZCHEM: 2Z
UNDG:
Dangerous Goods Class: 8 Subrisk: None
UN Number: 2967 Packing Group: III
Shipping Name:SULPHAMIC ACID
Air Transport IATA:
ICAO/IATA Class: 8 ICAO/IATA Subrisk: None
UN/ID Number: 2967 Packing Group: III
Special provisions: None
Shipping Name: SULPHAMIC ACID
SULFAMIC ACID
Chemwatch Material Safety Data Sheet (REVIEW)
Issue Date: 24-Jan-2007 CHEMWATCH 2967
NC317TCP Version No:4
CD 2007/3 Page 13 of 13
Section 14 - TRANSPORTATION INFORMATION
Maritime Transport IMDG:
IMDG Class: 8 IMDG Subrisk: None
UN Number: 2967 Packing Group: III
EMS Number: F- A, S- B Special provisions: None
Shipping Name: SULPHAMIC ACID
Section 15 - REGULATORY INFORMATION
POISONS SCHEDULE: S6
REGULATIONS
sulfamic acid (CAS: 5329-14-6) is found on the following regulatory lists;
Australia Inventory of Chemical Substances (AICS)
Australia Standard for the Uniform Scheduling of Drugs and Poisons (SUSDP) - Appendix E (Part 2)
Australia Standard for the Uniform Scheduling of Drugs and Poisons (SUSDP) - Appendix F (Part 3)
Australia Standard for the Uniform Scheduling of Drugs and Poisons (SUSDP) - Schedule 5
Australia Standard for the Uniform Scheduling of Drugs and Poisons (SUSDP) - Schedule 6
International Council of Chemical Associations (ICCA) - High Production Volume List
OECD Representative List of High Production Volume (HPV) Chemicals
Section 16 - OTHER INFORMATION
MSDS SECTION CHANGES
The following table displays the version number of and date on which each section was last changed.
Section Name Version Date Section Name Version Date Section Name Version Date
Advice to Doctor 4 24- Jan- 2007 Storage (storage 4 24- Jan- 2007 Instability 4 24- Jan- 2007
incompatibility) Condition
First Aid 4 24- Jan- 2007 Storage (storage 4 24- Jan- 2007 Acute Health (eye) 4 24- Jan- 2007
(inhaled) requirement)
First Aid (skin) 4 24- Jan- 2007 Storage (suitable 4 24- Jan- 2007 Acute Health 4 24- Jan- 2007
container) (inhaled)
First Aid 4 24- Jan- 2007 Engineering 4 24- Jan- 2007 Acute Health 4 24- Jan- 2007
(swallowed) Control (skin)
Fire Fighter 4 24- Jan- 2007 Exposure Standard 4 24- Jan- 2007 Acute Health 4 24- Jan- 2007
(extinguishing (swallowed)
media)
Fire Fighter (fire 4 24- Jan- 2007 Personal 4 24- Jan- 2007 Chronic Health 4 24- Jan- 2007
fighting) Protection (eye)
Fire Fighter (fire 4 24- Jan- 2007 Personal 4 24- Jan- 2007 Toxicity and 4 24- Jan- 2007
incompatibility) Protection Irritation (Other)
(hands/feet)
Fire Fighter 4 24- Jan- 2007 Personal 4 24- Jan- 2007 Environmental 4 24- Jan- 2007
(fire/explosion Protection (other)
hazard)
Spills (minor) 4 24- Jan- 2007 Physical 4 24- Jan- 2007 Disposal 4 24- Jan- 2007
Properties
Handling Procedure 4 24- Jan- 2007
Classification of the preparation and its individual components has drawn on official and
authoritative sources as well as independent review by the Chemwatch Classification
committee using available literature references.
This document is copyright. Apart from any fair dealing for the purposes of private study, research, review or
criticism, as permitted under the Copyright Act, no part may be reproduced by any process without written permission
from CHEMWATCH. TEL (+61 3) 9572 4700.
Issue Date: 24-Jan-2007
Print Date: 10-Jan-2008
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