SODIUM CYCLAMATE
Chemwatch Material Safety Data Sheet (REVIEW)
Issue Date: 12-May-2005 CHEMWATCH 49301
A317TC CD 2006/2 Page 1 of 9
Section 1 - CHEMICAL PRODUCT AND COMPANY IDENTIFICATION
PRODUCT NAME
SODIUM CYCLAMATE
SYNONYMS
C6-H13-N-O3-S, cyclamate, "cyclamic acid, sodium salt", "cyclohexanesulfamic
acid, monosodium salt", "N-cyclohexylsulfamic acid sodium salt", "sodium
cyclohexylsulfamate", "sodium cyclohexanesulfamate", "sodium cyclohexyl
amidosulfamate", "sodium cyclohexyl sulfamate", "sodium cyclohexylsulfamidate",
Assugrin, "Assurgrin Feinsuss", "Assurgrin Vollsuss", Asugryn, Dulzor-Etas,
Hachi-Sugar, Ibiosuc, Natreen, "Sucaryl sodium", Succaril, Sucrosa, "Sucrun 7",
Suesette, Suestamin, Sugarin, Sugaron
PRODUCT USE
Non-caloric sweetening agent about 30 times as sweet as refined cane-sugar.
Sweetness perceptible at 1:10000. Government regulation may restrict its use
and/or supply. Cyclamates are currently banned as food additives in many
countries (USA, UK, Canada, Sweden, Finland etc.)
SUPPLIER
Quantum Chemicals Pty Ltd
70 Quantum Close
Quantum Industrial Park
Dandenong South VIC 3175
Australia
Telephone: 1300 782 688
Emergency Tel: 1300 131 001
Fax: 1300 782 699
HAZARD RATINGS
Flammability
Toxicity
Body Contact
Reactivity
Chronic
SCALE: Min/Nil=0 Low=1 Moderate=2 High=3 Extreme=4
SODIUM CYCLAMATE
Chemwatch Material Safety Data Sheet (REVIEW)
Issue Date: 12-May-2005 CHEMWATCH 49301
A317TC CD 2006/2 Page 2 of 9
Section 2 - HAZARDS IDENTIFICATION
STATEMENT OF HAZARDOUS NATURE
NON-HAZARDOUS SUBSTANCE. NON-DANGEROUS GOODS. According to
the Criteria of NOHSC, and the ADG Code.
POISONS SCHEDULE
None
RISK
Limited evidence of a carcinogenic effect*.
* (limited evidence).
SAFETY
Do not breathe dust.
Avoid contact with skin.
Section 3 - COMPOSITION / INFORMATION ON INGREDIENTS
NAME CAS RN %
sodium cyclamate 139-05-9 >98
Section 4 - FIRST AID MEASURES
SWALLOWED
鈥? Immediately give a glass of water.
鈥? First aid is not generally required. If in doubt, contact a Poisons
Information Centre or a doctor.
EYE
If this product comes in contact with the eyes:
鈥? Wash out immediately with fresh running water.
鈥? Ensure complete irrigation of the eye by keeping eyelids apart and away from
eye and moving the eyelids by occasionally lifting the upper and lower lids.
鈥? If pain persists or recurs seek medical attention.
鈥? Removal of contact lenses after an eye injury should only be undertaken by
skilled personnel.
SKIN
If skin contact occurs:
鈥? Immediately remove all contaminated clothing, including footwear
鈥? Flush skin and hair with running water (and soap if available).
鈥? Seek medical attention in event of irritation.
INHALED
鈥? If dust is inhaled, remove from contaminated area.
鈥? Encourage patient to blow nose to ensure clear passage of breathing.
鈥? If irritation or discomfort persists seek medical attention.
NOTES TO PHYSICIAN
Treat symptomatically.
SODIUM CYCLAMATE
Chemwatch Material Safety Data Sheet (REVIEW)
Issue Date: 12-May-2005 CHEMWATCH 49301
A317TC CD 2006/2 Page 3 of 9
Section 5 - FIRE FIGHTING MEASURES
EXTINGUISHING MEDIA
鈥? Water spray or fog.
鈥? Foam.
鈥? Dry chemical powder.
鈥? BCF (where regulations permit).
鈥? Carbon dioxide.
FIRE FIGHTING
鈥? Use water delivered as a fine spray to control fire and cool adjacent area.
鈥? Do not approach containers suspected to be hot.
鈥? Cool fire exposed containers with water spray from a protected location.
鈥? If safe to do so, remove containers from path of fire.
鈥? Equipment should be thoroughly decontaminated after use.
FIRE/EXPLOSION HAZARD
鈥? Solid which exhibits difficult combustion or is difficult to ignite.
鈥? Avoid generating dust, particularly clouds of dust in a confined or
unventilated space as dusts may form an explosive mixture with air, and any
source of ignition, i.e. flame or spark, will cause fire or explosion. Dust
clouds generated by the fine grinding of the solid are a particular hazard;
accumulations of fine dust may burn rapidly and fiercely if ignited
鈥? Dry dust can also be charged electrostatically by turbulence, pneumatic
transport, pouring, in exhaust ducts and during transport.
鈥? Build-up of electrostatic charge may be prevented by bonding and grounding.
鈥? Powder handling equipment such as dust collectors, dryers and mills may
require additional protection measures such as explosion venting.
鈥? All movable parts coming in contact with this material should have a speed of
less than 1-meter/sec.
Combustion products include carbon monoxide (CO), sulfur oxides (SOx) and
nitrogen oxides (NOx).
FIRE INCOMPATIBILITY
Avoid contamination with strong oxidising agents as ignition may result.
HAZCHEM
None
Section 6 - ACCIDENTAL RELEASE MEASURES
EMERGENCY PROCEDURES
MINOR SPILLS
鈥? Clean up all spills immediately.
鈥? Avoid contact with skin and eyes.
鈥? Wear impervious gloves and safety glasses.
鈥? Use dry clean up procedures and avoid generating dust.
鈥? Sweep up or
鈥? Vacuum up (consider explosion-proof machines designed to be grounded during
storage and use).
鈥? Place spilled material in clean, dry, sealable, labelled container.
MAJOR SPILLS
鈥? Clear area of personnel and move upwind.
鈥? Alert Fire Brigade and tell them location and nature of hazard.
鈥? Control personal contact by using protective equipment and dust respirator.
鈥? Prevent spillage from entering drains, sewers or water courses.
SODIUM CYCLAMATE
Chemwatch Material Safety Data Sheet (REVIEW)
Issue Date: 12-May-2005 CHEMWATCH 49301
A317TC CD 2006/2 Page 4 of 9
Section 6 - ACCIDENTAL RELEASE MEASURES
鈥? Avoid generating dust.
鈥? Sweep, shovel up. Recover product wherever possible.
鈥? Put residues in labelled plastic bags or other containers for disposal.
鈥? If contamination of drains or waterways occurs, advise emergency services.
SAFE STORAGE WITH OTHER CLASSIFIED CHEMICALS
___________________________________________
+ + + + + +
___________________________________________
+: May be stored together
O: May be stored together with specific preventions
X: Must not be stored together
Personal Protective Equipment advice is contained in Section 8 of the MSDS.
Section 7 - HANDLING AND STORAGE
PROCEDURE FOR HANDLING
鈥? Limit all unnecessary personal contact.
鈥? Wear protective clothing when risk of exposure occurs.
鈥? Use in a well-ventilated area.
鈥? When handling DO NOT eat, drink or smoke.
鈥? Always wash hands with soap and water after handling.
鈥? Avoid physical damage to containers.
鈥? Use good occupational work practice.
鈥? Observe manufacturer's storing and handling recommendations.
SUITABLE CONTAINER
鈥? Polyethylene or polypropylene container.
鈥? Packing as recommended by manufacturer
鈥? Check all containers are clearly labelled and free from leaks.
STORAGE INCOMPATIBILITY
Avoid reaction with oxidising agents.
STORAGE REQUIREMENTS
鈥? Keep dry.
鈥? Store in original containers.
鈥? Keep containers securely sealed.
鈥? No smoking, naked lights or ignition sources.
鈥? Store in a cool, dry, well-ventilated area.
鈥? Store away from incompatible materials.
鈥? Protect containers against physical damage.
鈥? Check regularly for leaks.
鈥? Observe manufacturer's storing and handling recommendations.
Section 8 - EXPOSURE CONTROLS / PERSONAL PROTECTION
EXPOSURE CONTROLS
Source Material TWA TWA STEL STEL Peak Peak
ppm mg/m鲁 ppm m5/m鲁 ppm mg/m鲁
_________________________ ________________ _____ _____ _____ _____ _____ _____
Australia Exposure sodium cyclamate 10
SODIUM CYCLAMATE
Chemwatch Material Safety Data Sheet (REVIEW)
Issue Date: 12-May-2005 CHEMWATCH 49301
A317TC CD 2006/2 Page 5 of 9
Section 8 - EXPOSURE CONTROLS / PERSONAL PROTECTION
Source Material TWA TWA STEL STEL Peak Peak
ppm mg/m鲁 ppm m5/m鲁 ppm mg/m鲁
_________________________ ________________ _____ _____ _____ _____ _____ _____
Standards
The following materials had no OELs on our record under the following CAS or Chemwatch (CW) numbers
sodium cyclamate: No data available for CAS:139-05-9
These "dusts" have little adverse effect on the lungs and do not produce toxic
effects or organic disease. Although there is no dust which does not evoke some
cellular response at sufficiently high concentrations, the cellular response
caused by P.N.O.C.s has the following characteristics:
鈥? the architecture of the air spaces remain intact,
鈥? scar tissue (collagen) is not synthesised to any degree,
鈥? tissue reaction is potentially reversible.
Extensive concentrations of P.N.O.C.s may:
鈥? seriously reduce visibility,
鈥? cause unpleasant deposits in the eyes, ears and nasal passages,
鈥? contribute to skin or mucous membrane injury by chemical or mechanical action,
per se, or by the rigorous skin cleansing procedures necessary for their
removal. [ACGIH]
This limit does not apply:
鈥? to brief exposures to higher concentrations
鈥? nor does it apply to those substances that may cause physiological impairment
at lower concentrations but for which a TLV has as yet to be determined.
This exposure standard applies to particles which
鈥? are insoluble or poorly soluble* in water or, preferably, in aqueous lung
fluid (if data is available) and
鈥? have a low toxicity (i.e.. are not cytotoxic, genotoxic, or otherwise
chemically reactive with lung tissue, and do not emit ionizing radiation, cause
immune sensitization, or cause toxic effects other than by inflammation or by a
mechanism of lung overload).
PERSONAL PROTECTION
EYE
鈥? Safety glasses.
鈥? Safety glasses with side shields.
鈥? Chemical goggles.
鈥? Contact lenses may pose a special hazard; soft contact lenses may absorb and
concentrate irritants. A written policy document, describing the wearing of lens
or restrictions on use, should be created for each workplace or task. This
should include a review of lens absorption and adsorption for the class of
chemicals in use and an account of injury experience. Medical and first-aid
personnel should be trained in their removal and suitable equipment should be
readily available. In the event of chemical exposure, begin eye irrigation
immediately and remove contact lens as soon as practicable. Lens should be
removed at the first signs of eye redness or irritation - lens should be removed
in a clean environment only after workers have washed hands thoroughly. [CDC
NIOSH Current Intelligence Bulletin 59].
SODIUM CYCLAMATE
Chemwatch Material Safety Data Sheet (REVIEW)
Issue Date: 12-May-2005 CHEMWATCH 49301
A317TC CD 2006/2 Page 6 of 9
Section 8 - EXPOSURE CONTROLS / PERSONAL PROTECTION
HANDS/FEET
Wear general protective gloves, eg. light weight rubber gloves.
OTHER
Overalls.
鈥? Impervious protective clothing.
鈥? Eyewash unit.
RESPIRATOR
Protection Factor Half-Face Full-Face Powered Air
Respirator Respirator Respirator
10 x ES P1 Air-line* -- PAPR-P1 -
50 x ES Air-line** P2 PAPR-P2
100 x ES - P3 -
Air-line* -
100+ x ES - Air-line** PAPR-P3
* - Negative pressure demand ** - Continuous flow.
The local concentration of material, quantity and
conditions of use determine the type of personal
protective equipment required.
For further information consult site specific
CHEMWATCH data (if available), or your
Occupational Health and Safety Advisor.
ENGINEERING CONTROLS
General exhaust is adequate under normal operating conditions. If risk of
overexposure exists, wear SAA approved respirator. Correct fit is essential to
obtain adequate protection. Provide adequate ventilation in warehouse or closed
storage areas. Air contaminants generated in the workplace possess varying
"escape" velocities which, in turn, determine the "capture velocities" of fresh
circulating air required to effectively remove the contaminant.
Type of Contaminant: Air Speed:
solvent " "vapours " degreasing "etc. 0.25-0.5 m/s (50-100 f/min)
" evaporating from tank (in still air)
aerosols " fumes from pouring 0.5-1 m/s (100-200 f/min.)
"operations " intermittent container
"filling " low speed conveyer
"transfers " "welding " spray "drift "
plating acid "fumes " pickling
(released at low velocity into zone of
active generation)
direct "spray " spray painting in 1-2.5 m/s (200-500 f/min)
shallow "booths " drum "filling "
conveyer "loading " crusher "dusts "
gas discharge (active generation into
zone of rapid air motion)
grinding " abrasive "blasting " 2.5-10 m/s (500-2000 f/min.)
"tumbling " high speed wheel generated
dusts (released at high initial
velocity into zone of very high rapid
air motion).
Within each range the appropriate value depends on:
Lower end of the range Upper end of the range
1: Room air currents minimal or 1: Disturbing room air currents
favourable to capture
2: Contaminants of low toxicity or of 2: Contaminants of high toxicity
SODIUM CYCLAMATE
Chemwatch Material Safety Data Sheet (REVIEW)
Issue Date: 12-May-2005 CHEMWATCH 49301
A317TC CD 2006/2 Page 7 of 9
Section 8 - EXPOSURE CONTROLS / PERSONAL PROTECTION
nuisance value only
3: Intermittent, low production. 3: High production, heavy use
4: Large hood or large air mass in 4: Small hood - local control only
motion
Simple theory shows that air velocity falls rapidly with distance away from the
opening of a simple extraction pipe. Velocity generally decreases with the
square of distance from the extraction point (in simple cases). Therefore the
air speed at the extraction point should be adjusted, accordingly, after
reference to distance from the contaminating source. The air velocity at the
extraction fan, for example, should be a minimum of 1-2 m/s (200-400 f/min.) for
extraction of solvents generated in a tank 2 meters distant from the extraction
point. Other mechanical considerations, producing performance deficits within
the extraction apparatus, make it essential that theoretical air velocities are
multiplied by factors of 10 or more when extraction systems are installed or
used.
Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
APPEARANCE
White, sweet-tasting powder; mixes with water.
PHYSICAL PROPERTIES
Solid.
Mixes with water.
Molecular Weight: 201.22 Boiling Range (掳C): Not available
Melting Range (掳C): Not available Specific Gravity (water=1): Not available
Solubility in water (g/L): Miscible pH (as supplied): Not applicable
pH (1% solution): 5.5-7.5 Vapour Pressure (kPa): Negligible
Volatile Component (%vol): Negligible Evaporation Rate: Not applicable
Relative Vapour Density (air=1): >1 Flash Point (掳C): >300
Lower Explosive Limit (%): Not available Upper Explosive Limit (%): Not available.
Autoignition Temp (掳C): Not available Decomposition Temp (掳C): Not available.
State: Divided solid
Section 10 - CHEMICAL STABILITY AND REACTIVITY INFORMATION
CONDITIONS CONTRIBUTING TO INSTABILITY
鈥? Presence of incompatible materials.
鈥? Product is considered stable.
鈥? Hazardous polymerisation will not occur.
Section 11 - TOXICOLOGICAL INFORMATION
POTENTIAL HEALTH EFFECTS
ACUTE HEALTH EFFECTS
SWALLOWED
Considered an unlikely route of entry in commercial/industrial environments.
The material is moderately discomforting to the gastro-intestinal tract and may
be harmful if swallowed in large quantity.
SODIUM CYCLAMATE
Chemwatch Material Safety Data Sheet (REVIEW)
Issue Date: 12-May-2005 CHEMWATCH 49301
A317TC CD 2006/2 Page 8 of 9
Section 11 - TOXICOLOGICAL INFORMATION
EYE
The material is moderately discomforting to the eyes and is capable of causing a
mild, temporary redness of the conjunctiva (similar to wind-burn), temporary
impairment of vision and/ or other transient eye damage/ ulceration.
SKIN
The material may be mildly discomforting to the skin.
Open cuts, abraded or irritated skin should not be exposed to this material The
material may accentuate any pre-existing skin condition.
INHALED
The dust may be discomforting to the upper respiratory tract.
Persons with impaired respiratory function, airway diseases and conditions such
as emphysema or chronic bronchitis, may incur further disability if excessive
concentrations of particulate are inhaled.
CHRONIC HEALTH EFFECTS
Principal routes of exposure are usually by skin contact/absorption and
inhalation of generated dust.
TOXICITY AND IRRITATION
TOXICITY IRRITATION
Oral (rat) LD50: 15250 mg/kg Nil Reported
Intraperitoneal (rat) LD50: 1350 mg/kg
Subcutaneous (rat) LD50: 1280 mg/kg
Intravenous (rat) LD50: 3500 mg/kg
Oral (mouse) LD50: 17000 mg/kg
Intraperitoneal (mouse) LD50: 1154 mg/kg
Intravenous (mouse) LD50: 4800 mg/kg
Bladder tumours, foetolethality, effects on newborn, tumours at site of
application recorded.
The substance is classified by IARC as Group 3:
NOT classifiable as to its carcinogenicity to humans.
Evidence of carcinogenicity may be inadequate or limited in animal testing.
CARCINOGEN
IARC: International Agency for Research on Cancer (IARC)
Carcinogens: sodium cyclamate Category: Group 3: Not classifiable
as to carcinogenicity to humans
Section 12 - ECOLOGICAL INFORMATION
No data for sodium cyclamate.
Section 13 - DISPOSAL CONSIDERATIONS
鈥? Consult manufacturer for recycling options and recycle where possible .
鈥? Consult State Land Waste Management Authority for disposal.
鈥? Incinerate residue at an approved site.
鈥? Recycle containers if possible, or dispose of in an authorised landfill.
Section 14 - TRANSPORTATION INFORMATION
HAZCHEM
None
SODIUM CYCLAMATE
Chemwatch Material Safety Data Sheet (REVIEW)
Issue Date: 12-May-2005 CHEMWATCH 49301
A317TC CD 2006/2 Page 9 of 9
Section 14 - TRANSPORTATION INFORMATION
NOT REGULATED FOR TRANSPORT OF DANGEROUS GOODS:UN,IATA,IMDG
Section 15 - REGULATORY INFORMATION
POISONS SCHEDULE
None
REGULATIONS
sodium cyclamate (CAS: 139-05-9) is found on the following regulatory lists;
Australia Inventory of Chemical Substances (AICS)
International Agency for Research on Cancer (IARC) Carcinogens
Section 16 - OTHER INFORMATION
This document is copyright. Apart from any fair dealing for the purposes of
private study, research, review or criticism, as permitted under the Copyright
Act, no part may be reproduced by any process without written permission from
CHEMWATCH. TEL (+61 3) 9572 4700.
Issue Date: 12-May-2005
Print Date: 3-Jul-2006
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