SODIUM BROMIDE
Chemwatch Material Safety Data Sheet (REVIEW)
Issue Date: 30-Mar-2006 CHEMWATCH 21884
NC317TCP Version No:2.0
CD 2007/3 Page 1 of 9
Section 1 - CHEMICAL PRODUCT AND COMPANY IDENTIFICATION
PRODUCT NAME
SODIUM BROMIDE
SYNONYMS
NaBr, BrNa, "bromide salt of sodium", sedoneural
PRODUCT USE
Photography, medicine(sedative), preparation of bromides.
SUPPLIER
Company: Quantum Chemicals Pty Ltd
Address:
70 Quantum Close
Dandenong South
Victoria 3175
Telephone: 03 8795 8000
Emergency Tel: 1300 131 001
Fax: 03 8795 8099
HAZARD RATINGS
Flammability
Toxicity
Body Contact
Reactivity
Chronic
SCALE: Min/Nil=0 Low=1 Moderate=2 High=3 Extreme=4
Section 2 - HAZARDS IDENTIFICATION
STATEMENT OF HAZARDOUS NATURE
NON-HAZARDOUS SUBSTANCE. NON-DANGEROUS GOODS. According to the Criteria of
NOHSC, and the ADG Code.
POISONS SCHEDULE
S4
RISK SAFETY
Ingestion may produce health damage*. Do not breathe dust.
SODIUM BROMIDE
Chemwatch Material Safety Data Sheet (REVIEW)
Issue Date: 30-Mar-2006 CHEMWATCH 21884
NC317TCP Version No:2.0
CD 2007/3 Page 2 of 9
Section 2 - HAZARDS IDENTIFICATION
* (limited evidence). Take off immediately all contaminated clothing.
Section 3 - COMPOSITION / INFORMATION ON INGREDIENTS
NAME CAS RN %
sodium bromide 7647-15-6 > 99
sodium hypobromite 13824-96-9
Section 4 - FIRST AID MEASURES
SWALLOWED
For advice, contact a Poisons Information Centre or a doctor.
路 IF SWALLOWED, REFER FOR MEDICAL ATTENTION, WHERE POSSIBLE, WITHOUT DELAY.
路 For advice, contact a Poisons Information Centre or a doctor.
Where Medical attention is not immediately available or where the patient is more than 15
minutes from a hospital or unless instructed otherwise:
路 Induce vomiting with fingers down the back of the of the throat, ONLY IF CONSCIOUS.
路 Lean patient forward or place on left side (head-down position if possible) to maintain
open airway and prevent aspiration.
NOTE: Wear a protective glove when inducing vomiting by mechanical means.
路 In the mean time, qualified first-aid personnel should treat the patient following
observation and employing supportive measures as indicated by the patient's condition.
路 If the services of a medical officer or medical doctor are readily available, the
patient should be placed in his/her care and a copy of the MSDS should be provided.
Further action will be the responsibility of the medical specialist.
路 If medical attention is not available on the worksite or surroundings send the patient
to a hospital together with a copy of the MSDS.
EYE
If this product comes in contact with the eyes:
路 Wash out immediately with fresh running water.
路 Ensure complete irrigation of the eye by keeping eyelids apart and away from eye and
moving the eyelids by occasionally lifting the upper and lower lids.
路 If pain persists or recurs seek medical attention.
路 Removal of contact lenses after an eye injury should only be undertaken by skilled
personnel.
SKIN
If skin contact occurs:
路 Immediately remove all contaminated clothing, including footwear.
路 Flush skin and hair with running water (and soap if available).
路 Seek medical attention in event of irritation.
INHALED
路 If dust is inhaled, remove from contaminated area.
路 Encourage patient to blow nose to ensure clear passage of breathing.
路 If irritation or discomfort persists seek medical attention.
NOTES TO PHYSICIAN
Treatment of intoxication by the bromide ion includes hydration, the maintenance of mild
water diuresis, and sodium, or even better, ammonium chloride (10-15 gm. daily in divided
doses) with an osmotic or high ceiling diuretic. Haemodialysis may be of value. [GOSSELIN
, SMITH, HODGE: Clinical Toxicology of Commercial Products]
In acute poisoning the stomach should be emptied by aspiration and lavage and sodium
chloride given by intravenous infusion. Dextrose has also been administered and frusemide
may be given to aid diuresis. In severe cases of bromide intoxication or when usual
treatments cannot be used haemodialysis or peritoneal dialysis may be of value.
[MARTINDALE: The Extra Pharmacopoeia].
SODIUM BROMIDE
Chemwatch Material Safety Data Sheet (REVIEW)
Issue Date: 30-Mar-2006 CHEMWATCH 21884
NC317TCP Version No:2.0
CD 2007/3 Page 3 of 9
Section 4 - FIRST AID MEASURES
Section 5 - FIRE FIGHTING MEASURES
EXTINGUISHING MEDIA
路 There is no restriction on the type of extinguisher which may be used.
FIRE FIGHTING
Alert Fire Brigade and tell them location and nature of hazard.
Use fire fighting procedures suitable for surrounding area.
路 Wear breathing apparatus plus protective gloves.
路 Prevent, by any means available, spillage from entering drains or water courses.
Use water delivered as a fine spray to control the fire and cool adjacent area.
DO NOT approach containers suspected to be hot.
If safe to do so, remove containers from path of fire.
FIRE/EXPLOSION HAZARD
路 Non combustible.
路 Not considered a significant fire risk, however containers may burn.
HAZCHEM: None
Section 6 - ACCIDENTAL RELEASE MEASURES
EMERGENCY PROCEDURES
MINOR SPILLS
路 Clean up all spills immediately.
路 Avoid contact with skin and eyes.
路 Wear impervious gloves and safety glasses.
路 Use dry clean up procedures and avoid generating dust.
路 Sweep up or
路 Vacuum up (consider explosion-proof machines designed to be grounded during storage and
use).
路 Place spilled material in clean, dry, sealable, labelled container.
MAJOR SPILLS
路 Clear area of personnel and move upwind.
路 Alert Fire Brigade and tell them location and nature of hazard.
路 Control personal contact by using protective equipment and dust respirator.
路 Prevent spillage from entering drains, sewers or water courses.
路 Avoid generating dust.
路 Sweep, shovel up. Recover product wherever possible.
路 Put residues in labelled plastic bags or other containers for disposal.
路 If contamination of drains or waterways occurs, advise emergency services.
EMERGENCY RESPONSE PLANNING GUIDELINES (ERPG)
The maximum airborne concentration below which it is believed that nearly all individuals could be exposed
for up to one hour WITHOUT experiencing or developing
life-threatening health effects is:
sodium bromide 500 mg/m鲁
irreversible or other serious effects or symptoms which could impair an individual's ability to take
protective action is:
sodium bromide 35 mg/m鲁
SODIUM BROMIDE
Chemwatch Material Safety Data Sheet (REVIEW)
Issue Date: 30-Mar-2006 CHEMWATCH 21884
NC317TCP Version No:2.0
CD 2007/3 Page 4 of 9
Section 6 - ACCIDENTAL RELEASE MEASURES
other than mild, transient adverse effects without perceiving a clearly defined odour is:
sodium bromide 5 mg/m鲁
The threshold concentration below which most people will experience no appreciable risk of health effects:
sodium bromide 1.5 mg/m鲁
American Industrial Hygiene Association (AIHA)
Ingredients considered according to the following cutoffs
Very Toxic (T+) >= 0.1% Toxic (T) >= 3.0%
R50 >= 0.25% Corrosive (C) >= 5.0%
R51 >= 2.5%
else >= 10%
where percentage is percentage of ingredient found in the mixture
Personal Protective Equipment advice is contained in Section 8 of the MSDS.
Section 7 - HANDLING AND STORAGE
PROCEDURE FOR HANDLING
路 Limit all unnecessary personal contact.
路 Wear protective clothing when risk of exposure occurs.
路 Use in a well-ventilated area.
路 When handling DO NOT eat, drink or smoke.
路 Always wash hands with soap and water after handling.
路 Avoid physical damage to containers.
路 Use good occupational work practice.
路 Observe manufacturer's storing and handling recommendations.
SUITABLE CONTAINER
路 Check that containers are clearly labelled.
Packaging as recommended by manufacturer.
Glass container.
Metal can.
STORAGE INCOMPATIBILITY
Segregate from acids, alkaloidal and heavy
metal salts as well as strong oxidisers.
STORAGE REQUIREMENTS
Observe manufacturer's storing and handling recommendations.
Store in original containers.
Store in a cool, dry place.
DO NOT store near acids, or oxidising agents.
Keep containers securely sealed.
Protect containers against physical damage.
Check regularly for spills and leaks.
_____________________________________________________
SAFE STORAGE WITH OTHER CLASSIFIED CHEMICALS
+ + + + + +
_____________________________________________________
+: May be stored together
O: May be stored together with specific preventions
X: Must not be stored together
SODIUM BROMIDE
Chemwatch Material Safety Data Sheet (REVIEW)
Issue Date: 30-Mar-2006 CHEMWATCH 21884
NC317TCP Version No:2.0
CD 2007/3 Page 5 of 9
Section 8 - EXPOSURE CONTROLS / PERSONAL PROTECTION
EXPOSURE CONTROLS
Source Material TWA mg/m鲁
_________ _________ _____
Australia Exposure Standards sodium bromide (Inspirable dust 10
(Not specified))
Australia Exposure Standards sodium hypobromite (Inspirable 10
dust (Not specified))
MATERIAL DATA
These "dusts" have little adverse effect on the lungs and do not produce toxic effects or
organic disease. Although there is no dust which does not evoke some cellular response at
sufficiently high concentrations, the cellular response caused by P.N.O.C.s has the
following characteristics:
路 the architecture of the air spaces remain intact,
路 scar tissue (collagen) is not synthesised to any degree,
路 tissue reaction is potentially reversible.
Extensive concentrations of P.N.O.C.s may:
路 seriously reduce visibility,
路 cause unpleasant deposits in the eyes, ears and nasal passages,
路 contribute to skin or mucous membrane injury by chemical or mechanical action, per se,
or by the rigorous skin cleansing procedures necessary for their removal. [ACGIH]
This limit does not apply:
路 to brief exposures to higher concentrations
路 nor does it apply to those substances that may cause physiological impairment at lower
concentrations but for which a TLV has as yet to be determined.
This exposure standard applies to particles which
路 are insoluble or poorly soluble* in water or, preferably, in aqueous lung fluid (if
data is available) and
路 have a low toxicity (i.e.. are not cytotoxic, genotoxic, or otherwise chemically
reactive with lung tissue, and do not emit ionizing radiation, cause immune sensitization
, or cause toxic effects other than by inflammation or by a mechanism of lung overload).
INGREDIENT DATA
SODIUM HYPOBROMITE:
These "dusts" have little adverse effect on the lungs and do not produce toxic effects or
organic disease. Although there is no dust which does not evoke some cellular response at
sufficiently high concentrations, the cellular response caused by P.N.O.C.s has the
following characteristics:
路 the architecture of the air spaces remain intact,
路 scar tissue (collagen) is not synthesised to any degree,
路 tissue reaction is potentially reversible.
Extensive concentrations of P.N.O.C.s may:
路 seriously reduce visibility,
路 cause unpleasant deposits in the eyes, ears and nasal passages,
路 contribute to skin or mucous membrane injury by chemical or mechanical action, per se,
or by the rigorous skin cleansing procedures necessary for their removal. [ACGIH]
This limit does not apply:
路 to brief exposures to higher concentrations
路 nor does it apply to those substances that may cause physiological impairment at lower
concentrations but for which a TLV has as yet to be determined.
This exposure standard applies to particles which
路 are insoluble or poorly soluble* in water or, preferably, in aqueous lung fluid (if
data is available) and
路 have a low toxicity (i.e.. are not cytotoxic, genotoxic, or otherwise chemically
reactive with lung tissue, and do not emit ionizing radiation, cause immune sensitization
, or cause toxic effects other than by inflammation or by a mechanism of lung overload).
SODIUM BROMIDE
Chemwatch Material Safety Data Sheet (REVIEW)
Issue Date: 30-Mar-2006 CHEMWATCH 21884
NC317TCP Version No:2.0
CD 2007/3 Page 6 of 9
Section 8 - EXPOSURE CONTROLS / PERSONAL PROTECTION
PERSONAL PROTECTION
EYE
路 Safety glasses.
路 Contact lenses may pose a special hazard; soft contact lenses may absorb and
concentrate irritants. A written policy document, describing the wearing of lens or
restrictions on use, should be created for each workplace or task. This should include a
review of lens absorption and adsorption for the class of chemicals in use and an account
of injury experience. Medical and first-aid personnel should be trained in their removal
and suitable equipment should be readily available. In the event of chemical exposure,
begin eye irrigation immediately and remove contact lens as soon as practicable. Lens
should be removed at the first signs of eye redness or irritation - lens should be
removed in a clean environment only after workers have washed hands thoroughly. [CDC
NIOSH Current Intelligence Bulletin 59].
HANDS/FEET
Wear general protective gloves, eg. light weight rubber gloves.
OTHER
Ensure there is ready access to a safety shower.
路 Eyewash unit.
路 Skin cleansing cream.
Overalls.
RESPIRATOR
Protection Factor Half- Face Respirator Full- Face Respirator Powered Air Respirator
10 x ES P1 Air- line* -- PAPR- P1 -
50 x ES Air- line** P2 PAPR- P2
100 x ES - P3 -
Air- line* -
100+ x ES - Air- line** PAPR- P3
* - Negative pressure demand ** - Continuous flow.
The local concentration of material, quantity and conditions of use determine the type of
personal protective equipment required.
For further information consult site specific
CHEMWATCH data (if available), or your
Occupational Health and Safety Advisor.
ENGINEERING CONTROLS
General exhaust is adequate under normal operating conditions. If risk of overexposure
exists, wear SAA approved respirator. Correct fit is essential to obtain adequate
protection. Provide adequate ventilation in warehouse or closed storage areas. Air
contaminants generated in the workplace possess varying "escape" velocities which, in
turn, determine the "capture velocities" of fresh circulating air required to effectively
remove the contaminant.
Type of Contaminant: Air Speed:
solvent, vapours, degreasing etc., evaporating 0.25- 0.5 m/s (50- 100 f/min)
from tank (in still air)
SODIUM BROMIDE
Chemwatch Material Safety Data Sheet (REVIEW)
Issue Date: 30-Mar-2006 CHEMWATCH 21884
NC317TCP Version No:2.0
CD 2007/3 Page 7 of 9
Section 8 - EXPOSURE CONTROLS / PERSONAL PROTECTION
aerosols, fumes from pouring operations, 0.5- 1 m/s (100- 200 f/min.)
intermittent container filling, low speed
conveyer transfers, welding, spray drift,
plating acid fumes, pickling (released at low
velocity into zone of active generation)
direct spray, spray painting in shallow booths, 1- 2.5 m/s (200- 500 f/min)
drum filling, conveyer loading, crusher dusts,
gas discharge (active generation into zone of
rapid air motion)
grinding, abrasive blasting, tumbling, high 2.5- 10 m/s (500- 2000 f/min.)
speed wheel generated dusts (released at high
initial velocity into zone of very high rapid
air motion).
Within each range the appropriate value depends on:
Lower end of the range Upper end of the range
1: Room air currents minimal or favourable to 1: Disturbing room air currents
capture
2: Contaminants of low toxicity or of nuisance 2: Contaminants of high toxicity
value only
3: Intermittent, low production. 3: High production, heavy use
4: Large hood or large air mass in motion 4: Small hood - local control only
Simple theory shows that air velocity falls rapidly with distance away from the opening
of a simple extraction pipe. Velocity generally decreases with the square of distance
from the extraction point (in simple cases). Therefore the air speed at the extraction
point should be adjusted, accordingly, after reference to distance from the contaminating
source. The air velocity at the extraction fan, for example, should be a minimum of 1-2
m/s (200-400 f/min.) for extraction of solvents generated in a tank 2 meters distant from
the extraction point. Other mechanical considerations, producing performance deficits
within the extraction apparatus, make it essential that theoretical air velocities are
multiplied by factors of 10 or more when extraction systems are installed or used.
Section 9 - PHYSICAL AND CHEMICAL PROPERTIES
APPEARANCE
White crystalline solid; granular or powder with saline bitter odour. Absorbs moisture
from air but is not deliquescent. Very soluble in water, moderately soluble in
alcohol.Aqueous solution is practically neutral, pH: 6.5- 8.0
PHYSICAL PROPERTIES
Solid.
Mixes with water.
Molecular Weight: 102.89 Boiling Range (掳C): 1390
Melting Range (掳C): 747 Specific Gravity (water=1): 3.203 @ 25 C
Solubility in water (g/L): Miscible pH (as supplied): Not applicable
pH (1% solution): Not available. Vapour Pressure (kPa): Negligible
Volatile Component (%vol): Negligible Evaporation Rate: Not applicable
Relative Vapour Density (air=1): Not applicable. Flash Point (掳C): Not applicable
Lower Explosive Limit (%): Not applicable Upper Explosive Limit (%): Not applicable
Autoignition Temp (掳C): Not applicable Decomposition Temp (掳C): Not available.
State: Divided solid
SODIUM BROMIDE
Chemwatch Material Safety Data Sheet (REVIEW)
Issue Date: 30-Mar-2006 CHEMWATCH 21884
NC317TCP Version No:2.0
CD 2007/3 Page 8 of 9
Section 10 - CHEMICAL STABILITY AND REACTIVITY INFORMATION
CONDITIONS CONTRIBUTING TO INSTABILITY
路 Presence of incompatible materials.
路 Product is considered stable.
路 Hazardous polymerisation will not occur.
Section 11 - TOXICOLOGICAL INFORMATION
POTENTIAL HEALTH EFFECTS
ACUTE HEALTH EFFECTS
SWALLOWED
The material is moderately discomforting to the gastro-intestinal tract and may be
harmful if swallowed in large quantity.
Bromide poisoning causes intense vomiting so the dose is often removed. Effects include
drowsiness, irritability, inco-ordination, vertigo, confusion, mania, hallucinations and
coma. Other effects include skin rash, nervous system symptoms, sensory disturbances and
increased spinal fluid pressure. They have been used as sedatives and depress the central
nervous system. Toxicity is increased if dietary chloride is reduced. Repeated ingestion
can cause a syndrome with acne, confusion, irritability, tremor, memory loss, weight loss
, headache, slurred speech, delusions, stupor, psychosis and coma.
EYE
The dust may produce eye discomfort causing smarting, pain and redness.
SKIN
The material is moderately discomforting to the skin.
INHALED
The dust may be discomforting to the upper respiratory tract.
Persons with impaired respiratory function, airway diseases and conditions such as
emphysema or chronic bronchitis, may incur further disability if excessive concentrations
of particulate are inhaled.
CHRONIC HEALTH EFFECTS
As with any chemical product, contact with unprotected bare skin; inhalation of vapour,
mist or dust in work place atmosphere; or ingestion in any form, should be avoided by
observing good occupational work practice.
TOXICITY AND IRRITATION
TOXICITY IRRITATION
Oral (rat) LD50: 3500 mg/kg Nil Reported
SODIUM HYPOBROMITE:
No significant acute toxicological data identified in literature search.
Section 12 - ECOLOGICAL INFORMATION
Aquatic toxicity *:
Fathead minnow 96hr LC50: 16479 mg/L
Poecilia reticulata 96hr LC50: 225 mg/L
Daphnia magna 48hr LC50: 7900 mg/L
[*Nalco]
Refer to data for ingredients, which follows:
SODIUM BROMIDE
Chemwatch Material Safety Data Sheet (REVIEW)
Issue Date: 30-Mar-2006 CHEMWATCH 21884
NC317TCP Version No:2.0
CD 2007/3 Page 9 of 9
Section 12 - ECOLOGICAL INFORMATION
SODIUM HYPOBROMITE:
Aquatic Toxicity *:
Bluegill sunfish 96hr LC50: 0.52 mg/L (as Br2)
Rainbow trout 96hr LC50:0.23 mg/L (as Br2)
Sheephead minnow 96hr LC50: 0.19 mg/L (as Br2)
Daphnia magna 48hr LC50: 0.71 mg/L (as Br2)
Eastern oysters 96hr EC50: 0.54 mg/L (as Br2)
Mysid Shrimp 96hr LC50: 0.17 mg/L (as Br2)
[*Nalco]
Section 13 - DISPOSAL CONSIDERATIONS
路 Recycle wherever possible or consult manufacturer for recycling options.
路 Consult State Land Waste Management Authority for disposal.
路 Bury residue in an authorised landfill.
路 Recycle containers if possible, or dispose of in an authorised landfill.
Section 14 - TRANSPORTATION INFORMATION
HAZCHEM: None
NOT REGULATED FOR TRANSPORT OF DANGEROUS GOODS:UN, IATA,
IMDG
Section 15 - REGULATORY INFORMATION
POISONS SCHEDULE: S4
REGULATIONS
sodium bromide (CAS: 7647-15-6) is found on the following regulatory lists;
Australia Exposure Standards
Australia Inventory of Chemical Substances (AICS)
Australia Standard for the Uniform Scheduling of Drugs and Poisons (SUSDP) - Schedule 4
OECD Representative List of High Production Volume (HPV) Chemicals
Section 16 - OTHER INFORMATION
Classification of the preparation and its individual components has drawn on official and
authoritative sources as well as independent review by the Chemwatch Classification
committee using available literature references.
This document is copyright. Apart from any fair dealing for the purposes of private study, research, review or
criticism, as permitted under the Copyright Act, no part may be reproduced by any process without written permission
from CHEMWATCH. TEL (+61 3) 9572 4700.
Issue Date: 30-Mar-2006
Print Date: 10-Jan-2008
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