MATERIAL SAFETY DATA SHEET
SECTION 1 - PRODUCT IDENTIFICATION AND USE
PRODUCT IDENTIFICATION NUMBER (PIN):
PRODUCT IDENTIFIER
Glutaraldehyde 24% Solution GL110X
PRODUCT USE
Fixative for tissues
MANUFACTURERS NAME: SUPPLIERS NAME:
Xenex Labs XENEX LABORATORIES INC.
STREET ADDRESS: STREET ADDRESS:
2402 CANOE AVENUE
CITY: PROVINCE: CITY: PROVINCE:
COQUITLAM B.C.
POSTAL CODE: EMERGENCY TELEPHONE NO: POSTAL CODE: EMERGENCY TELEPHONE NO:
SPE100 V3K 6C2 (CHEMTREC) 1-800-424-9300
SECTION 2 - HAZARDOUS INGREDIENTS
HAZARDOUS INGREDIENTS
% CAS NUMBER LD50 / LC50 OF INGREDIENT
/ CHEMICAL FORMULA
(SPECIFY SPECIES) (SPECIFY ROUTE AND DOSE)
Glutaraldehyde 24% Solution
鈥? Water 7732-18-5 75.5 - 76.5 Not Available Not Available
鈥? Glutaraldehyde 111-30-8 23.5 - 24.5 RAT ORAL 134mg/kg
MOUSE ORAL 100 mg/kg
RAT DERMAL 2500 mg/kg
MOUSE DERMAL 5840 mg/kg
RAT MIST 480mg /m鲁 4 hours
SECTION 3 - PHYSICAL DATA
PHYSICAL STATE AND APPEARANCE ODOR TASTE ODOR THRESHOLD (ppm)
Liquid (Clear, Colorless) Not Available Not Available 0.04 ppm (Glutaraldehyde)
MELTING POINT (C) BOILING POINT (C) VAPOR PRESSURE VAPOR DENSITY VOLATILITY
-6掳C (21.2掳F) 101掳c (213.8掳F) 2.3 kPa (@ 20掳C) (Glutaraldehyde) 1.05 Not Available
pH SPECIFIC GRAVITY COEFF. WATER/OIL DIST.
3.5 [Acidic.] 1.062 Not Available
DISPERSION PROPERTIES / SOLUBILITY
Easily soluble in cold water. Soluble in diethyl ether. Soluble in benzene, ethanol and other organic solvents.
SECTION 4 - FIRE AND EXPLOSION DATA
NO YES
FLAMMABILITY IF YES, UNDER WHAT CONDITIONS?
Non-Flammable
MEANS OF EXTINCTION
Not Applicable
FLASHPOINT (C) AND METHOD FLAMMABLE LIMITS (% BY VOLUME) CRITICAL TEMPERATURE
Not Available UPPER: Not Available LOWER: Not Available Not Available
AUTOIGNITION TEMPERATURE (C) HAZARDOUS COMBUSTION PRODUCTS
Not Available Not Applicable
SECTION 5 - REACTIVITY DATA
YES NO IF NO, UNDER WHICH CONDITIONS?
CHEMICAL STABILITY
The product is stable - Avoid exposure to air, and excess heat
NO YES
INCOMPATIBILITY WITH OTHER SUBSTANCES IF SO, WHICH ONES?
Slightly reactive to reactive with oxidizing agents, alkalis
REACTIVITY, AND UNDER WHAT CONDITIONS
Also incompatible with amines, ammonia and other caustics (e.g. ammonium hydroxide, calcium hydroxide, potassium
hydroxide, and sodium hydroxide).
Alkaline solutions react with alcohol, ketones, amines, hydrazine's and proteins. (Glutaraldehyde)
HAZARDOUS DECOMPOSITION PRODUCTS
The products of degradation are less toxic than the product itself
MATERIAL SAFETY DATA SHEET
GL110X
PRODUCT IDENTIFIER
Glutaraldehyde 24% Solution
SECTION 6 - TOXICOLOGICAL PROPERTIES
ROUTE OF ENTRY
INGESTION
INHALATION
SKIN CONTACT SKIN ABSORPTION EYE CONTACT
EFFECTS OF ACUTE EXPOSURE TO PRODUCT
Hazardous in case of skin contact (irritant), of eye contact (irritant), of ingestion, of inhalation (lung irritant, lung
sensitizer). Slightly hazardous in case of skin contact (sensitizer, permeator). Severe over-exposure can result in death.
Eye: Causes severe eye irritation. May cause eye injury or chemical conjunctivitis.
Skin: Causes moderate to severe skin irritation. It may be absorbed through the skin, although poorly. May cause allergic
contact dermatitis with itching and skin rash. May cause staining of the skin and nails to a brown or golden brown color.
Ingestion: Harmful if swallowed. Can cause severe irritation of the digestive tract with burning sensation in the chest,
abdominal pain, cramping, nausea, vomiting, diarrhea (perhaps bloody diarrhea), vascular collapse, and coma. May also
affect liver (increased liver enzymes, liver damage), blood (normocytic anemia), behavior (somnolence, excitement,
dizziness, lethargy, ataxia, muscle twitching, seizures), kidneys( abnormal renal function, anuria). it may possibly cause
burns of the mouth, throat, esophagus, and stomach.
Inhalation: Harmful if inhaled. Can cause respiratory tract and mucous membrane irritation (nasal and throat irritation),
and sudden headaches, nausea, and vomiting, coughing, shortness of breath, chest pain, inflammation of the mucous
membrane of the nasal cavites, nose bleeds when exposed to vapor or mist. May cause asthma. May also affect
respiration, metabolism (weight loss), cardiovascular system (palpitations, tachycardia).
EFFECTS OF CHRONIC EXPOSURE TO PRODUCT
CARCINOGENIC EFFECTS: Classified A4 (Not classifiable for human or animal.) by ACGIH [Glutaraldehyde].
MUTAGENIC EFFECTS: Mutagenic for mammalian somatic cells. [Glutaraldehyde]. Mutagenic for bacteria and/or
yeast. [Glutaraldehyde].
May affect genetic material (mutagenic).
May cause adverse reproductive effects. (Glutaraldehyde)
The substance may be toxic to lungs, upper respiratory tract, skin, eyes, central nervous system (CNS). Repeated or
prolonged exposure to the substance can produce target organs damage. Repeated exposure to a highly toxic material
may produce general deterioration of health by an accumulation in one or many human organs. Contains material which
may cause damage to the following organs: lungs, upper respiratory tract, skin, eyes, central nervous system (CNS).
Hazardous in case of skin contact (irritant), of ingestion, of inhalation (lung irritant, lung sensitizer). Slightly hazardous in
case of skin contact (sensitizer, permeator).
Skin: Glutaraldehyde is a skin sensitizer and prolonged or repeated skin contact can cause dermatoses and allergic
contact dermatitis.
Ingestion: Prolonged or repeated ingestion may affect the spleen, liver (fatty liver degeneration), kidney damage and
cause weight loss.
Inhalation: Prolonged or repeated inhalation may cause weight loss.
EXPOSURE LIMITS
TWA: 0.2 (ppm) [Australia] TWA: 0.82 (mg/m3) [Australia]
TWA: 0.25
CEIL: 0.2 (ppm) from NIOSH CEIL: 0.2 (ppm) from OSHA (PEL) [United States]
TWA: 0.05 STEL: 0.05 (ppm) [United Kingdom (UK)]
SYNERGISTIC PRODUCTS
IRRITANCY OF PRODUCT SENSITIZATION OF PRODUCT
Yes Yes Not Available
REPRODUCTIVE TOXICITY MUTAGENICITY
TERATOGENICITY CARCINOGENICITY
Not Available Possible As Specified As Specified
MATERIAL SAFETY DATA SHEET
GL110X
PRODUCT IDENTIFIER
Glutaraldehyde 24% Solution
SECTION 7 - PREVENTATIVE MEASURE
PERSONAL PROTECTIVE EQUIPMENT
GLOVES (SPECIFY) RESPIRATOR (SPECIFY) EYE (SPECIFY)
Yes ( impervious ) Approved / Certified respirator Safety goggles, face shield
FOOTWEAR (SPECIFY) CLOTHING (SPECIFY) OTHER (SPECIFY)
No Coveralls / Lab coat Eyewash equipment nearby
ENGINEERING CONTROLS (SPECIFY eg. VENTILATION, ENCLOSED PROCESS)
Provide exhaust ventilation or other engineering controls to keep the airborne concentrations of vapors below their
respective threshold limit value. Ensure that eyewash stations and safety showers are proximal to the work-station
location.
LEAK AND SPILL PROCEDURE
Dilute with water and mop up or absorb with an inert material and put the spilled material in an appropriate waste
disposal.
WASTE DISPOSAL
According to local, provincial, and federal regulations.
HANDLING PROCEDURES AND EQUIPMENT
Keep locked up, Keep away from heat. Keep away from sources of ignition. Do not ingest. Empty containers pose a fire
risk, evaporate the residue under a fume hood. Ground all equipment containing material. Do not breathe gas/fumes/
vapor/spray. Wear suitable protective clothing. In case of insufficient ventilation, wear suitable respiratory equipment. If
you feel unwell, seek medical attention and show the label when possible. Avoid contact with skin and eyes. Keep away
from incompatibles.
STORAGE REQUIREMENTS
Refrigerate. Keep container tightly closed. Keep container in a cool, dry, well-ventilated area. Container may be
hazardous when empty since they retain product residues observe all warnings and precautions listed for the product.
SPECIAL SHIPPING INFORMATION
Not a DOT controlled material.
CLASS D-1B: Material causing immediate and serious toxic effects (TOXIC).
CLASS D-2B: Material causing other toxic effects (TOXIC).
SECTION 8 - FIRST AID MEASURES
SPECIFIC MEASURES
In case of contact, immediately flush skin with plenty of water for at least 15 minutes while
SKIN
removing contaminated clothing and shoes. Cover the irritated skin with an emollient. Cold water
may be used. Wash clothing before reuse. Thoroughly clean shoes before reuse. Get medical
attention.
Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of
EYES
water for at least 15 minutes. Get medical attention immediately
If inhaled remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give
INHALATION
oxygen. Get medical attention immediately.
INGESTION Do NOT induce vomiting unless directed to do so by medical personnel. Never give anything by
mouth to an unconscious person. Loosen tight clothing such as collar, tie, belt or waistband. Get
medical attention immediately
IF IRRITATION PERSISTS AND IN ALL OTHER CASES, GET IMMEDIATE MEDICAL ATTENTION.
SECTION 9 - PREPARATION DATE OF M.S.D.S.
All chemicals may pose unknown hazards and should be used with caution. This Material Safety Data Sheet (MSDS) applies only to the material as packa
If this product is combined with other materials, deteriorates, or becomes contaminated, it may pose hazards not mentioned in this MSDS. It shall be the us
responsibility to develop proper methods of handling and personal protection based on the actual conditions of use. While this MSDS is based on technical
data judged to be reliable, Xenex Laboratories Inc. assumes no responsibility for the completeness or accuracy of the information contained herein.
PREPARED BY (GROUP, DEPARTMENT, ETC.) PHONE NUMBER DATE:
CONTROL DEPARTMENT (604) 552 3031 May 29 2007
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