MATERIAL SAFETY DATA SHEET
SECTION 1 - PRODUCT IDENTIFICATION AND USE
PRODUCT IDENTIFICATION NUMBER (PIN):
PRODUCT IDENTIFIER
Isopropyl alcohol, 99% IS170X
PRODUCT USE
MANUFACTURERS NAME: SUPPLIERS NAME:
Xenex Labs XENEX LABORATORIES INC.
STREET ADDRESS: STREET ADDRESS:
2402 CANOE AVENUE
CITY: PROVINCE: CITY: PROVINCE:
COQUITLAM B.C.
POSTAL CODE: EMERGENCY TELEPHONE NO: POSTAL CODE: EMERGENCY TELEPHONE NO:
SPE100 V3K 6C2 (CHEMTREC) 1-800-424-9300
SECTION 2 - HAZARDOUS INGREDIENTS
HAZARDOUS INGREDIENTS
% CAS NUMBER LD50 / LC50 OF INGREDIENT
/ CHEMICAL FORMULA
(SPECIFY SPECIES) (SPECIFY ROUTE AND DOSE)
Isopropyl alcohol, 99% 100 67-63-0 RAT ORAL 5045 mg/kg
C3H8O MOUSE ORAL 3600 mg/kg
RABBIT ORAL 6410 mg/kg
RABBIT DERMAL 12800 mg/kg
SECTION 3 - PHYSICAL DATA
PHYSICAL STATE AND APPEARANCE ODOR TASTE ODOR THRESHOLD (ppm)
Liquid (Colorless) Bitter (Slight) Not Available
Like acetone and ethanol
MELTING POINT (C) BOILING POINT (C) VAPOR PRESSURE @ 20掳C VAPOR DENSITY (Air=1) VOLATILITY
-88.5掳C (-127.3掳F) 82.5掳C (180.5掳F) 4.4 kPa 2.07 Not Available
pH SPECIFIC GRAVITY COEFF. WATER/OIL DIST.
Not Available 0.78505 The product is equally soluble in oil and water: log (oil/water)=0.1
DISPERSION PROPERTIES / SOLUBILITY
Easily soluble in cold water, hot water, methanol, diethyl ether, n-octanol, acetone. Insoluble in salt solution. Soluble in benzene. Miscible with most organic
solvents including alcohol, ethyl alcohol, chloroform.
SECTION 4 - FIRE AND EXPLOSION DATA
NO YES
FLAMMABILITY IF YES, UNDER WHAT CONDITIONS?
Flammable - Highly flammable in presence of open flames and sparks, of heat. Flammable in presence of oxidizing materials. Non-flammable in presence of
shocks. Vapor may travel considerable distance to source of ignition and flash back.
CAUTION: MAY BURN WITH NEAR INVISIBLE FLAME Hydrogen .
peroxide sharply reduces the autoignition temperature of Isopropyl alcohol. After a delay, Isopropyl alcohol ignites on contact with dioxgenyl tetrafluorborate,
chromium trioxide, and potassium tert-butoxide. When heated to decomposition it emits acrid smoke and fumes.
Explosive Hazards
Explosive in presence of open flames and sparks, of heat. Secondary alcohols are readily auto oxidized in contact with oxygen or air, forming ketones and
hydrogen peroxide. It can become potentially explosive. It reacts with oxygen to form dangerously unstable peroxides which can concentrate and explode
during distillation or evaporation. The presence of 2-butanone (or other ketones) increases the reaction rate for peroxide formation. Explosive in the form of
vapor when exposed to heat or flame. May form explosive mixtures with air. Isopropyl alcohol + phosgene forms isopropyl chloroformate and hydrogen
chloride. In the presence of iron salts, thermal decomposition can occur, which in some cases can become explosive. A homogeneous mixture of concentr
peroxides + isopropyl alcohol are capable of detonation by shock or heat.
Barium perchlorate + isopropyl alcohol gives the highly explosive alkyl perchlorates. It forms explosive mixtures with trinitormethane and hydrogen peroxide. It
produces a violent explosive reaction when heated with aluminum isopropoxide + crotonaldehyde. Mixtures of isopropyl alcohol + nitroform are explosive.
MEANS OF EXTINCTION
Flammable liquid, soluble or dispersed in water.
SMALL: Use DRY chemical powder.
LARGE: Use water spray, fog or alcohol foam. Do
NOT use water jet.
FLAMMABLE LIMITS (% BY VOLUME) AUTOIGNITION TEMPERATURE (C) CRITICAL TEMPERATURE
UPPER: 12.7% LOWER: 2% 399掳C (750.2掳F) 235掳C (455掳F)
FLASHPOINT (C) AND METHOD
CLOSED CUP: 11.7掳C (53.1掳F). - 12.778 deg. C (55 deg. F) (TAG)
HAZARDOUS COMBUSTION PRODUCTS
(CO,CO2) Oxides of carbon. Acrid smoke and fume
MATERIAL SAFETY DATA SHEET
IS170X
PRODUCT IDENTIFIER
Isopropyl alcohol, 99%
SECTION 5 - REACTIVITY DATA
YES NO IF NO, UNDER WHICH CONDITIONS?
CHEMICAL STABILITY
The product is stable - Avoid Heat, ignition sources (flames, sparks, static), incompatible materials
NO YES
INCOMPATIBILITY WITH OTHER SUBSTANCES IF SO, WHICH ONES?
Reactive with oxidizing agents, acids, alkalis.
REACTIVITY, AND UNDER WHAT CONDITIONS
Reacts violently with hydrogen + palladium combination, nitroform, oleum, COCl2, aluminum triisopropoxide, oxidants.
Incompatible with acetaldehyde, chlorine, ethylene oxide, isocyanates, acids, alkaline earth, alkali metals, caustics,
amines, crotonaldehyde, phosgene, ammonia. Isopropyl alcohol reacts with metallic aluminum at high temperatures.
Isopropyl alcohol attacks some plastics, rubber, and coatings. Vigorous reaction with sodium dichromate + sulfuric acid.
HAZARDOUS DECOMPOSITION PRODUCTS
Ecotoxicity in water (LC50): 100000 mg/l 96 hours [Fathead Minnow]. 64000 mg/l 96 hours [Fathead Minnow].
The product itself and its products of degradation are not toxic.
SECTION 6 - TOXICOLOGICAL PROPERTIES
ROUTE OF ENTRY
INGESTION
INHALATION
SKIN CONTACT SKIN ABSORPTION EYE CONTACT
EFFECTS OF ACUTE EXPOSURE TO PRODUCT
Hazardous in case of eye contact (irritant), of inhalation. Slightly hazardous in case of skin contact (irritant, sensitizer,
permeator), of ingestion May cause mild skin irritation, and sensitization. Can cause eye irritation. Breathing in small
amounts of this material during normal handling is not likely to cause harmful effects. However, breathing large amounts
may be harmful and may affect the respiratory system and mucous membranes (irritation), behavior and brain (Central
nervous system depression - headache, dizziness, drowsiness, stupor, incoordination, unconsciousness, coma and
possible death), peripheral nerve and sensation, blood, urinary system, and liver. Swallowing small amounts during
normal handling is not likely to cause harmful effects.
Swallowing large amounts may be harmful. Swallowing large amounts may cause gastrointestinal tract irritation with
nausea, vomiting and diarrhea, abdominal pain. It also may affect the urinary system, cardiovascular system, sense
organs, behavior or central nervous system (somnolence, generally depressed activity, irritability, headache, dizziness,
drowsiness), liver, and respiratory system (breathing difficulty).
EFFECTS OF CHRONIC EXPOSURE TO PRODUCT
CARCINOGENIC EFFECTS: A4 (Not classifiable for human or animal.) by ACGIH, 3 (Not classifiable for human.) by
IARC.
May cause adverse reproductive/teratogenic effects (fertility, fetotoxicity, developmental abnormalities (developmental
toxin)) based on animal studies. Detected in maternal milk in human.
Hazardous in case of inhalation. Slightly hazardous in case of skin contact (irritant, sensitizer, permeator), of ingestion.
May cause damage to the following organs: kidneys, liver, skin, central nervous system (CNS). Repeated or prolonged
exposure to the substance can produce target organs damage. May cause defatting of the skin and dermatitis and
allergic reaction. May cause adverse reproductive effects based on animal data (studies).
EXPOSURE LIMITS
TWA: 983 STEL: 1230 (mg/m3) [Australia]
TWA: 980 STEL: 1225 (mg/m3) from NIOSH TWA: 400 STEL: 500 (ppm) from NIOSH
TWA: 400 STEL: 500 (ppm) [United Kingdom (UK)] TWA: 999 STEL: 1259 (mg/m3) [United Kingdom (UK)]
TWA: 400 STEL: 500 (ppm) from OSHA (PEL) [United States] TWA: 980 STEL: 1225 (mg/m3) from OSHA (PEL) [United States]
TWA: 200 STEL: 400 (ppm) from ACGIH (TLV) [United States] [1999]
Consult local authorities for acceptable exposure limits.
SYNERGISTIC PRODUCTS
IRRITANCY OF PRODUCT SENSITIZATION OF PRODUCT
Yes Yes Not Available
REPRODUCTIVE TOXICITY MUTAGENICITY
TERATOGENICITY CARCINOGENICITY
Possible Possible Not Available A4
MATERIAL SAFETY DATA SHEET
IS170X
PRODUCT IDENTIFIER
Isopropyl alcohol, 99%
SECTION 7 - PREVENTATIVE MEASURE
PERSONAL PROTECTIVE EQUIPMENT
GLOVES (SPECIFY) RESPIRATOR (SPECIFY) EYE (SPECIFY)
Yes ( impervious ) Approved / Certified respirator Safety goggles, face shield
FOOTWEAR (SPECIFY) CLOTHING (SPECIFY) OTHER (SPECIFY)
No Coveralls / Lab coat Eyewash equipment nearby
ENGINEERING CONTROLS (SPECIFY eg. VENTILATION, ENCLOSED PROCESS)
Provide exhaust ventilation or other engineering controls to keep the airborne concentrations of vapors below their
respective threshold limit value. Ensure that eyewash stations and safety showers are proximal to the work-station
location.
LEAK AND SPILL PROCEDURE
Flammable liquid. Keep away from heat. Keep away from sources of ignition. Stop leak if without risk. Absorb with DRY
earth, sand or other non-combustible material. Do not touch spilled material. Prevent entry into sewers, basements or
confined areas; dike if needed. Be careful that the product is not present at a concentration level above TLV. Check TLV
on the MSDS and with local authorities.
WASTE DISPOSAL
According to local, provincial, and federal regulations.
HANDLING PROCEDURES AND EQUIPMENT
Keep away from heat. Keep away from sources of ignition. Empty containers pose a fire risk, evaporate the residue
under a fume hood. Ground all equipment containing material. Do not breathe gas/fumes/ vapor/spray. Wear suitable
protective clothing. In case of insufficient ventilation, wear suitable respiratory equipment. If you feel unwell, seek
medical attention and show the label when possible. Avoid contact with skin and eyes. Keep away from incompatibles
such as oxidizing agents, acids.
STORAGE REQUIREMENTS
Store in a segregated and approved area. Keep container in a cool, well-ventilated area. Keep container tightly closed
and sealed until ready for use. Avoid all possible sources of ignition (spark or flame).
SPECIAL SHIPPING INFORMATION
DOT CLASS 3: Flammable liquid. .
WHMIS (Canada) CLASS B-2: Flammable liquid with a flash point lower than 37.8掳C (100掳F).
WHMIS (Canada) CLASS D-2B: Material causing other toxic effects (TOXIC).
SECTION 8 - FIRST AID MEASURES
SPECIFIC MEASURES
Wash with soap and water. Cold water may be used. Cover the irritated skin with an emollient.
SKIN
Remove contaminated clothing and shoes. Get medical attention if irritation develops. Wash
clothing before reuse, thoroughly clean shoes before reuse.
Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of
EYES
water for at least 15 minutes. Cold water may be used. Get medical attention
If inhaled remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give
INHALATION
oxygen. Get medical attention if symptoms appear.
INGESTION Do NOT induce vomiting unless directed to do so by medical personnel. Never give anything by
mouth to an unconscious person. Loosen tight clothing such as collar, tie, belt or waistband. Get
medical attention if symptoms appear.
IF IRRITATION PERSISTS AND IN ALL OTHER CASES, GET IMMEDIATE MEDICAL ATTENTION.
SECTION 9 - PREPARATION DATE OF M.S.D.S.
All chemicals may pose unknown hazards and should be used with caution. This Material Safety Data Sheet (MSDS) applies only to the material as packa
If this product is combined with other materials, deteriorates, or becomes contaminated, it may pose hazards not mentioned in this MSDS. It shall be the us
responsibility to develop proper methods of handling and personal protection based on the actual conditions of use. While this MSDS is based on technical
data judged to be reliable, Xenex Laboratories Inc. assumes no responsibility for the completeness or accuracy of the information contained herein.
PREPARED BY (GROUP, DEPARTMENT, ETC.) PHONE NUMBER DATE:
CONTROL DEPARTMENT (604) 552 3031 January 18 2007
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