Page 1 of 30
@Beckman
Coulter® Kit MSDS
Doc. ID: A17116-75: Rev. AA
Product Information
Allergenicity Kit
Product Name
Doc. ID A17116-75 AA
Issued (year/month/day) 2004/06/01
Part Number A17116
Series Name:
Additional Product For In Vitro Diagnostic Use. See product literature for details.
Information:
Components
Description
Three color mixture
Stop Solution
Activation Solution
IgE Antibody
Fixative Solution
VersaLyse Lysing Solution
Transport Information
Transportation of this product is not regulated under ICAO, IMDG, US DOT, European ADR or Canadian TDG.
?2004 Beckman Coulter, Inc.
Global MSDS ? English
Page 2 of 30
@Beckman
Coulter® MATERIAL SAFETY DATA SHEET
Section 1 Company and Product Identification
Three color mixture
Product Name Allergenicity Kit
Doc. ID A17116-75 AA
Issued (year/month/day) 2004/06/01
Part Number Component of P/N A17116
Manufacturer Distributed by Beckman Coulter, Inc. for
IMMUNOTECH (A Beckman Coulter Company)
130, av.de Lattre de Tassigny—BP 177
13276 Marseille Cedex 09—France Tèl. (33) 4 91 17 27 00
¤
Distributor and Refer to attached list, Document ID: 472050, for local distributor and
Emergency Phone No. emergency phone numbers.
Section 2 Composition and Information on Ingredients
Hazardous Ingredients: Meets Hazardous Criteria:
Chemical Name CAS # % by wt. EU US OSHA WHMIS
Sodium Azide 26628-22-8 0.1% T+;R28 R32 No No
See Section 15 Regulatory Information for additional information on hazard classifications.
Section 3 Hazards Identification
Emergency Overview
Light pink; Translucent; Liquid; Odorless
Nonflammable aqueous solution.
Harmful if swallowed.
Contains material of animal origin.
Physical Hazards Sodium azide forms explosive compounds with heavy metals. Repeated contact of
low concentrations of azide with lead and copper commonly found in plumbing drains
may result in the build up of shock sensitive compounds.
Potential Health This product contains material of animal origin and should be considered as
Effects Summary potentially capable of transmitting infectious diseases.
See Section 11 Toxicological Information for more detailed health information.
Product Hazard EU: WHMIS: US OSHA:
Classifications Xn;R22 Not applicable Not applicable
Beckman Coulter Safety Flammability (Section V): 0 Code
Rating Health (Section XI): 1 0=none
Reactivity with Water (Section X): 0 1=slight
Contact (Section VIII): 1 2=caution
3=severe
Section 4 First Aid Measures
Inhalation If product is inhaled, move exposed individual to fresh air. If individual is not
breathing, begin artificial respiration immediately and obtain medical attention.
Allergenicity Kit Doc. ID: A17116-75 AA Page 3 of 30
Three color mixture
Section 4 First Aid Measures (Continued)
Eye Contact If product enters eyes, wash eyes gently under running water for 15 minutes or
longer, making sure that the eyelids are held open. If pain or irritation occur, obtain
medical attention.
Skin Contact In case of skin contact, flush with copious amounts of water for at least 15 minutes.
Remove contaminated clothing and shoes. If pain or irritation occur, obtain medical
attention.
Ingestion If ingested, wash mouth out with water. If irritation or discomfort occurs, seek medical
attention.
Section 5 Fire Fighting Measures
Flash Point Not applicable
Flammable Limits Not applicable
Autoignition Temp. Not applicable
Extinguishing Media Use extinguishing media suitable for surrounding fire.
Special Fire and None identified.
Explosion Hazards
Hazardous Combustion Due to the composition and volume of this product, combustion products generated
Products from it are not expected to present a significant hazard.
Protective Equipment Self-contained breathing apparatus is recommended for firefighters.
for Firefighters
Section 6 Accidental Release Measures
Personal Precautions This product contains a material of biological origin. Use universal precautions during
clean up procedures.
Spill and Leak As a precautionary measure, treat spilled material with a 1:10 bleach/water solution.
Procedures Absorb liquid and place in container suitable for disposal. Avoid generation of
aerosols during clean up. Comply with applicable waste disposal regulations.
Environmental Contain spill to prevent migration.
Precautions
Section 7 Handling and Storage
Handling Precautions This product should be handled as though capable of transmitting infectious diseases.
Universal precautions should be followed when using this product.
Recommended Storage Keep away from incompatible material.
Conditions To maintain efficacy, store according to the instructions in the product labeling.
Section 8 Exposure Controls and Personal Protection
Exposure Limits
US OSHA: None established
Allergenicity Kit Doc. ID: A17116-75 AA Page 4 of 30
Three color mixture
Section 8 Exposure Controls and Personal Protection (Continued)
ACGIH:
Sodium Azide 0.29 mg/m3 Ceiling (as sodium azide); 0.11 ppm Ceiling (as
Hydrazoic acid, vapor)
DFG MAK:
Sodium Azide 0.2 mg/m3 MAK (inhalable fraction); 0.4 mg/m3 Peak (inhalable fraction)
Engineering Controls No special engineering controls are required. Use with good general ventilation.
Respiratory Protection Under normal conditions, the use of this product should not require respiratory
protection.
Eye Protection Safety glasses or chemical goggles should be worn to prevent eye contact.
Skin Protection Impervious gloves, such as latex or equivalent, should be worn to prevent skin
contact.
Section 9 Physical and Chemical Properties
Physical State Liquid
Color Light pink
Transparency Translucent
Odor Odorless
Odor Threshold Not applicable
pH 7.2
Boiling Point Not available
Melting Point Not available
Specific Gravity 1.005 @20°C
Vapor Pressure Not available
Vapor Density Not available
Evaporation Rate Not available
Solubility
Water Miscible
Organic Not available
Section 10 Stability and Reactivity
Stability Stable in closed containers under normal temperatures and pressures.
Hazardous Strong acids
Incompatibilities Strong bases
Strong oxidizers
Metals and metallic compounds
Sodium azide forms explosive compounds with heavy metals. Repeated contact of
low concentrations of azide with lead and copper commonly found in plumbing drains
may result in the build up of shock sensitive compounds.
Allergenicity Kit Doc. ID: A17116-75 AA Page 5 of 30
Three color mixture
Section 10 Stability and Reactivity (Continued)
Hazardous No decomposition products posing significant hazards would be expected from this
Decomposition Products product (a dilute aqueous solution).
Conditions to Avoid Avoid contact with incompatible materials.
Section 11 Toxicological Information
Toxicity Data
for Hazardous Ingredients
Sodium Azide Oral LD50 Rat: 27 mg/kg; Oral LD50 Mouse: 27 mg/kg; Dermal LD50 Rabbit:
20 mg/kg
Primary Routes Common routes of entry include inhalation, ingestion and eye/skin contact. Specific
of Exposure paths of concern for potentially infectious materials are skin puncture, contact with
broken skin, contact with mucous membranes and inhalation of aerosolized material.
Potential Effects of This product contains material of animal origin and should be considered as
Acute Exposure potentially capable of transmitting infectious diseases.
Although its concentration in this product is low, sodium azide is highly toxic by
ingestion and skin absorption. Overexposure may result in irritation of skin, eyes and
mucous membranes, lowered blood pressure and irregular heartbeat. Sodium azide
is a chemical asphyxiant and may effect the cardiovascular, respiratory and central
nervous systems. Symptoms may include irritation, severe, pounding headaches,
dizziness, weakness, nausea, vomiting, low blood pressure, rapid heartbeat,
convulsions, collapse and death.
Potential Effects of Prolonged or repeated exposure to sodium azide may result in pounding headaches,
Chronic Exposure eye and nose irritation, low blood pressure, fatigue and dizziness.
Symptoms of Symptoms of overexposure may include: eye, skin, nose and throat irritation;
Overexposure headache, weakness, dizziness, confusion, nausea and vomiting. Severe cases
may exhibit difficulty in breathing, irregular heartbeat, reddish colored skin,
unconsciousness, convulsions, coma and death. Symptoms may be delayed for
several hours after exposure.
Carcinogenicity No ingredients in this product are listed as carcinogens by ACGIH, IARC, NTP, OSHA
or 67/548/EEC Annex I.
Other Effects Reproductive effects have been reported in animal studies.
Conditions Aggravated None identified.
by Exposure
Section 12 Ecological Information
Ecotoxicity Toxic to fish and other water organisms.
Biodegradability No information available.
Mobility No information available.
Section 13 Disposal Considerations
Waste Disposal Dispose of waste product, unused product and contaminated packaging in compliance
with federal, state and local regulations. If unsure of the applicable requirements,
contact the authorities for information.
Sodium azide preservative may form explosive compounds in metal drain lines. See
NIOSH Bulletin: Explosive Azide Hazard (8/16/76).
Allergenicity Kit Doc. ID: A17116-75 AA Page 6 of 30
Three color mixture
Section 14 Transport Information
Transportation of this product is not regulated under ICAO, IMDG, US DOT, European ADR or Canadian TDG.
Section 15 Regulatory Information
US Federal and State Regulations
SARA 313 Sodium Azide is subject to reporting requirements of Section 313, Title III of SARA.
CERCLA RG’s, Sodium Azide is listed.
40 CFR 302.4
California Proposition 65 No ingredients listed
Massachusetts MSL Sodium Azide is listed.
New Jersey Dept. of Sodium Azide is listed.
Health RTK List
Pennsylvania RTK Sodium Azide is listed.
EU Labeling Classification
Classification Risk and Safety Phrases
Xn R22 Harmful if swallowed.
S28 After contact with skin, wash immediately with plenty of water.
Harmful
Canada
This product does not meet WHMIS criteria for hazardous materials.
PIN: Not applicable
Ingredients on Ingredient Sodium Azide
Disclosure List:
Ingredients with unknown None
toxicological properties:
Section 16 Other Information
For further information, please contact your local Beckman Coulter representative.
WHILE BECKMAN COULTER, INC. BELIEVES THE INFORMATION CONTAINED HEREIN IS VALID AND ACCURATE, BECKMAN COULTER MAKES NO WARRANTY OR
REPRESENTATION AS TO ITS VALIDITY, ACCURACY, OR CURRENCY. BECKMAN COULTER SHALL NOT BE LIABLE OR OTHERWISE RESPONSIBLE IN ANY WAY FOR USE
OF EITHER THIS INFORMATION OR MATERIALS TO WHICH IT APPLIES. DISPOSAL OF HAZARDOUS MATERIALS MAY BE SUBJECT TO LOCAL LAWS OR REGULATIONS.
Printed in U.S.A.
Page 7 of 30
@Beckman
Coulter® MATERIAL SAFETY DATA SHEET
Section 1 Company and Product Identification
Stop Solution
Product Name
Allergenicity Kit
Doc. ID A17116-75 AA
Issued (year/month/day) 2004/06/01
Part Number Component of P/N A17116
Manufacturer Distributed by Beckman Coulter, Inc. for
IMMUNOTECH (A Beckman Coulter Company)
130, av.de Lattre de Tassigny—BP 177
13276 Marseille Cedex 09—France Tèl. (33) 4 91 17 27 00
¤
Distributor and Refer to attached list, Document ID: 472050, for local distributor and
Emergency Phone No. emergency phone numbers.
Section 2 Composition and Information on Ingredients
Hazardous Ingredients: Meets Hazardous Criteria:
Chemical Name CAS # % by wt. EU US OSHA WHMIS
Sodium Azide 26628-22-8 0.1% T+;R28 R32 No No
See Section 15 Regulatory Information for additional information on hazard classifications.
Section 3 Hazards Identification
Emergency Overview
Colorless; Clear; Liquid; Odorless
Nonflammable aqueous solution.
Harmful if swallowed.
Contains material of animal origin.
Physical Hazards Sodium azide forms explosive compounds with heavy metals. Repeated contact of
low concentrations of azide with lead and copper commonly found in plumbing drains
may result in the build up of shock sensitive compounds.
Potential Health This product contains material of animal origin and should be considered as
Effects Summary potentially capable of transmitting infectious diseases.
See Section 11 Toxicological Information for more detailed health information.
Product Hazard EU: WHMIS: US OSHA:
Classifications Xn;R22 Not applicable Not applicable
Beckman Coulter Safety Flammability (Section V): 0 Code
Rating Health (Section XI): 1 0=none
Reactivity with Water (Section X): 0 1=slight
Contact (Section VIII): 1 2=caution
3=severe
Section 4 First Aid Measures
Inhalation If product is inhaled, move exposed individual to fresh air. If individual is not
breathing, begin artificial respiration immediately and obtain medical attention.
Allergenicity Kit Doc. ID: A17116-75 AA Page 8 of 30
Stop Solution
Section 4 First Aid Measures (Continued)
Eye Contact If product enters eyes, wash eyes gently under running water for 15 minutes or
longer, making sure that the eyelids are held open. If pain or irritation occur, obtain
medical attention.
Skin Contact In case of skin contact, flush with copious amounts of water for at least 15 minutes.
Remove contaminated clothing and shoes. If pain or irritation occur, obtain medical
attention.
Ingestion If ingested, wash mouth out with water. If irritation or discomfort occurs, seek medical
attention.
Section 5 Fire Fighting Measures
Flash Point Not applicable
Flammable Limits Not applicable
Autoignition Temp. Not applicable
Extinguishing Media Use extinguishing media suitable for surrounding fire.
Special Fire and None identified.
Explosion Hazards
Hazardous Combustion Due to the composition and volume of this product, combustion products generated
Products from it are not expected to present a significant hazard.
Protective Equipment Self-contained breathing apparatus is recommended for firefighters.
for Firefighters
Section 6 Accidental Release Measures
Personal Precautions This product contains a material of biological origin. Use universal precautions during
clean up procedures.
Spill and Leak As a precautionary measure, treat spilled material with a 1:10 bleach/water solution.
Procedures Absorb liquid and place in container suitable for disposal. Avoid generation of
aerosols during clean up. Comply with applicable waste disposal regulations.
Environmental Contain spill to prevent migration.
Precautions
Section 7 Handling and Storage
Handling Precautions This product should be handled as though capable of transmitting infectious diseases.
Universal precautions should be followed when using this product.
Recommended Storage Keep away from incompatible material.
Conditions To maintain efficacy, store according to the instructions in the product labeling.
Section 8 Exposure Controls and Personal Protection
Exposure Limits
US OSHA: None established
Allergenicity Kit Doc. ID: A17116-75 AA Page 9 of 30
Stop Solution
Section 8 Exposure Controls and Personal Protection (Continued)
ACGIH:
Sodium Azide 0.29 mg/m3 Ceiling (as sodium azide); 0.11 ppm Ceiling (as
Hydrazoic acid, vapor)
DFG MAK:
Sodium Azide 0.2 mg/m3 MAK (inhalable fraction); 0.4 mg/m3 Peak (inhalable fraction)
Engineering Controls No special engineering controls are required. Use with good general ventilation.
Respiratory Protection Under normal conditions, the use of this product should not require respiratory
protection.
Eye Protection Safety glasses or chemical goggles should be worn to prevent eye contact.
Skin Protection Impervious gloves, such as latex or equivalent, should be worn to prevent skin
contact.
Section 9 Physical and Chemical Properties
Physical State Liquid
Color Colorless
Transparency Clear
Odor Odorless
Odor Threshold Not applicable
pH 8
Boiling Point Not available
Melting Point Not available
Specific Gravity 1.01 @20°C
Vapor Pressure Not available
Vapor Density Not available
Evaporation Rate Not available
Solubility
Water Miscible
Organic Not available
Section 10 Stability and Reactivity
Stability Stable in closed containers under normal temperatures and pressures.
Hazardous Strong acids
Incompatibilities Strong bases
Strong oxidizers
Metals and metallic compounds
Sodium azide forms explosive compounds with heavy metals. Repeated contact of
low concentrations of azide with lead and copper commonly found in plumbing drains
may result in the build up of shock sensitive compounds.
Allergenicity Kit Doc. ID: A17116-75 AA Page 10 of 30
Stop Solution
Section 10 Stability and Reactivity (Continued)
Hazardous No decomposition products posing significant hazards would be expected from this
Decomposition Products product (a dilute aqueous solution).
Conditions to Avoid Avoid contact with incompatible materials.
Section 11 Toxicological Information
Toxicity Data
for Hazardous Ingredients
Sodium Azide Oral LD50 Rat: 27 mg/kg; Oral LD50 Mouse: 27 mg/kg; Dermal LD50 Rabbit:
20 mg/kg
Primary Routes Common routes of entry include inhalation, ingestion and eye/skin contact. Specific
of Exposure paths of concern for potentially infectious materials are skin puncture, contact with
broken skin, contact with mucous membranes and inhalation of aerosolized material.
Potential Effects of This product contains material of animal origin and should be considered as
Acute Exposure potentially capable of transmitting infectious diseases.
Although its concentration in this product is low, sodium azide is highly toxic by
ingestion and skin absorption. Overexposure may result in irritation of skin, eyes and
mucous membranes, lowered blood pressure and irregular heartbeat. Sodium azide
is a chemical asphyxiant and may effect the cardiovascular, respiratory and central
nervous systems. Symptoms may include irritation, severe, pounding headaches,
dizziness, weakness, nausea, vomiting, low blood pressure, rapid heartbeat,
convulsions, collapse and death.
Potential Effects of Prolonged or repeated exposure to sodium azide may result in pounding headaches,
Chronic Exposure eye and nose irritation, low blood pressure, fatigue and dizziness.
Symptoms of Symptoms of overexposure may include: eye, skin, nose and throat irritation;
Overexposure headache, weakness, dizziness, confusion, nausea and vomiting. Severe cases
may exhibit difficulty in breathing, irregular heartbeat, reddish colored skin,
unconsciousness, convulsions, coma and death. Symptoms may be delayed for
several hours after exposure.
Carcinogenicity No ingredients in this product are listed as carcinogens by ACGIH, IARC, NTP, OSHA
or 67/548/EEC Annex I.
Other Effects Reproductive effects have been reported in animal studies.
Conditions Aggravated None identified.
by Exposure
Section 12 Ecological Information
Ecotoxicity Toxic to fish and other water organisms.
Biodegradability No information available.
Mobility No information available.
Section 13 Disposal Considerations
Waste Disposal Dispose of waste product, unused product and contaminated packaging in compliance
with federal, state and local regulations. If unsure of the applicable requirements,
contact the authorities for information.
Sodium azide preservative may form explosive compounds in metal drain lines. See
NIOSH Bulletin: Explosive Azide Hazard (8/16/76).
Allergenicity Kit Doc. ID: A17116-75 AA Page 11 of 30
Stop Solution
Section 14 Transport Information
Transportation of this product is not regulated under ICAO, IMDG, US DOT, European ADR or Canadian TDG.
Section 15 Regulatory Information
US Federal and State Regulations
SARA 313 Sodium Azide is subject to reporting requirements of Section 313, Title III of SARA.
CERCLA RG’s, Edetic Acid is listed.
40 CFR 302.4 Sodium Azide is listed.
California Proposition 65 No ingredients listed
Massachusetts MSL Edetic Acid is listed.
Sodium Azide is listed.
New Jersey Dept. of Edetic Acid is listed.
Health RTK List Sodium Azide is listed.
Pennsylvania RTK Edetic Acid is listed.
Sodium Azide is listed.
EU Labeling Classification
Classification Risk and Safety Phrases
Xn R22 Harmful if swallowed.
S28 After contact with skin, wash immediately with plenty of water.
Harmful
Canada
This product does not meet WHMIS criteria for hazardous materials.
PIN: Not applicable
Ingredients on Ingredient Sodium Azide
Disclosure List:
Ingredients with unknown None
toxicological properties:
Section 16 Other Information
For further information, please contact your local Beckman Coulter representative.
WHILE BECKMAN COULTER, INC. BELIEVES THE INFORMATION CONTAINED HEREIN IS VALID AND ACCURATE, BECKMAN COULTER MAKES NO WARRANTY OR
REPRESENTATION AS TO ITS VALIDITY, ACCURACY, OR CURRENCY. BECKMAN COULTER SHALL NOT BE LIABLE OR OTHERWISE RESPONSIBLE IN ANY WAY FOR USE
OF EITHER THIS INFORMATION OR MATERIALS TO WHICH IT APPLIES. DISPOSAL OF HAZARDOUS MATERIALS MAY BE SUBJECT TO LOCAL LAWS OR REGULATIONS.
Printed in U.S.A.
Page 12 of 30
@Beckman
Coulter® MATERIAL SAFETY DATA SHEET
Section 1 Company and Product Identification
Activation Solution
Product Name Allergenicity Kit
Doc. ID A17116-75 AA
Issued (year/month/day) 2004/06/01
Part Number Component of P/N A17116
Manufacturer Distributed by Beckman Coulter, Inc. for
IMMUNOTECH (A Beckman Coulter Company)
130, av.de Lattre de Tassigny—BP 177
13276 Marseille Cedex 09—France Tèl. (33) 4 91 17 27 00
¤
Distributor and Refer to attached list, Document ID: 472050, for local distributor and
Emergency Phone No. emergency phone numbers.
Section 2 Composition and Information on Ingredients
Hazardous Ingredients: None
Section 3 Hazards Identification
Emergency Overview
Colorless; Clear; Liquid; Odorless
Nonflammable aqueous solution.
Does not meet EU, OSHA or WHMIS criteria for hazardous materials.
Physical Hazards No physical hazards were determined from a review of available literature.
Potential Health This product does not meet EU, OSHA or WHMIS criteria for hazardous materials.
Effects Summary
Product Hazard EU: WHMIS: US OSHA:
Classifications Not applicable Not applicable Not applicable
Beckman Coulter Safety Flammability (Section V): 0 Code
Rating Health (Section XI): 0 0=none
Reactivity with Water (Section X): 0 1=slight
Contact (Section VIII): 1 2=caution
3=severe
Section 4 First Aid Measures
Inhalation If product is inhaled, move exposed individual to fresh air. If individual is not
breathing, begin artificial respiration immediately and obtain medical attention.
Eye Contact If product enters eyes, wash eyes gently under running water for 15 minutes or
longer, making sure that the eyelids are held open. If pain or irritation occur, obtain
medical attention.
Skin Contact In case of skin contact, flush with copious amounts of water for at least 15 minutes. If
pain or irritation occur, obtain medical attention.
Ingestion If ingested, wash mouth out with water. If irritation or discomfort occurs, seek medical
attention.
Allergenicity Kit Doc. ID: A17116-75 AA Page 13 of 30
Activation Solution
Section 5 Fire Fighting Measures
Flash Point Not applicable
Flammable Limits Not applicable
Autoignition Temp. Not applicable
Extinguishing Media Use extinguishing media suitable for surrounding fire.
Special Fire and None identified.
Explosion Hazards
Hazardous Combustion No combustion products posing significant hazards are expected from this product (an
Products aqueous solution).
Protective Equipment Self-contained breathing apparatus is recommended for firefighters.
for Firefighters
Section 6 Accidental Release Measures
Personal Precautions No special precautions are necessary. Use good laboratory procedures.
Spill and Leak Absorb spilled material with an appropriate inert, non-flammable absorbent and
Procedures dispose according to local regulations.
Environmental Contain spill to prevent migration.
Precautions
Section 7 Handling and Storage
Handling Precautions No special precautions are necessary; use good laboratory procedures.
Recommended Storage To maintain efficacy, store according to the instructions in the product labeling.
Conditions
Section 8 Exposure Controls and Personal Protection
Exposure Limits
US OSHA: None established
ACGIH: None established
DFG MAK: None established
Engineering Controls No special engineering controls are required. Use with good general ventilation.
Respiratory Protection Under normal conditions, the use of this product should not require respiratory
protection.
Eye Protection Safety glasses or chemical goggles should be worn to prevent eye contact.
Skin Protection Impervious gloves, such as latex or equivalent, should be worn to prevent skin
contact.
Section 9 Physical and Chemical Properties
Physical State Liquid
Allergenicity Kit Doc. ID: A17116-75 AA Page 14 of 30
Activation Solution
Section 9 Physical and Chemical Properties (Continued)
Color Colorless
Transparency Clear
Odor Odorless
Odor Threshold Not applicable
pH 7.4
Boiling Point Not available
Melting Point Not available
? 1.01 @20°C
Specific Gravity
Vapor Pressure Not available
Vapor Density Not available
Evaporation Rate Not available
Solubility
Water Miscible
Organic Not available
Section 10 Stability and Reactivity
Stability Stable in closed containers under normal temperatures and pressures.
Hazardous Strong acids
Incompatibilities Strong bases
Strong oxidizers
Hazardous No decomposition products posing significant hazards would be expected from this
Decomposition Products product (a dilute aqueous solution).
Conditions to Avoid Avoid contact with incompatible materials.
Section 11 Toxicological Information
Toxicity Data Not applicable
for Hazardous Ingredients
Primary Routes Eye contact, ingestion, inhalation, and skin contact.
of Exposure
Potential Effects of None identified.
Acute Exposure
Potential Effects of None identified.
Chronic Exposure
Symptoms of No specific symptoms identified.
Overexposure
Carcinogenicity No ingredients in this product are listed as carcinogens by ACGIH, IARC, NTP, OSHA
or 67/548/EEC Annex I.
Other Effects None identified.
Conditions Aggravated None identified.
by Exposure
Allergenicity Kit Doc. ID: A17116-75 AA Page 15 of 30
Activation Solution
Section 12 Ecological Information
Ecotoxicity No information available.
Biodegradability No information available.
Mobility No information available.
Section 13 Disposal Considerations
Waste Disposal Dispose of waste product, unused product and contaminated packaging in compliance
with federal, state and local regulations. If unsure of the applicable requirements,
contact the authorities for information.
Section 14 Transport Information
Transportation of this product is not regulated under ICAO, IMDG, US DOT, European ADR or Canadian TDG.
Section 15 Regulatory Information
US Federal and State Regulations
SARA 313 No ingredients listed
CERCLA RG’s, No ingredients listed
40 CFR 302.4
California Proposition 65 No ingredients listed
Massachusetts MSL No ingredients listed
New Jersey Dept. of No ingredients listed
Health RTK List
Pennsylvania RTK No ingredients listed
EU Labeling Classification
Preparation not classified.
Canada
This product does not meet WHMIS criteria for hazardous materials.
PIN: Not applicable
Ingredients on Ingredient None
Disclosure List:
Ingredients with unknown None
toxicological properties:
Section 16 Other Information
For further information, please contact your local Beckman Coulter representative.
WHILE BECKMAN COULTER, INC. BELIEVES THE INFORMATION CONTAINED HEREIN IS VALID AND ACCURATE, BECKMAN COULTER MAKES NO WARRANTY OR
REPRESENTATION AS TO ITS VALIDITY, ACCURACY, OR CURRENCY. BECKMAN COULTER SHALL NOT BE LIABLE OR OTHERWISE RESPONSIBLE IN ANY WAY FOR USE
OF EITHER THIS INFORMATION OR MATERIALS TO WHICH IT APPLIES. DISPOSAL OF HAZARDOUS MATERIALS MAY BE SUBJECT TO LOCAL LAWS OR REGULATIONS.
Printed in U.S.A.
Page 16 of 30
@Beckman
Coulter® MATERIAL SAFETY DATA SHEET
Section 1 Company and Product Identification
IgE Antibody
Product Name
Allergenicity Kit
Doc. ID A17116-75 AA
Issued (year/month/day) 2004/06/01
Part Number Component of P/N A17116
Product Use Data given is for reconstituted solution.
Manufacturer Distributed by Beckman Coulter, Inc. for
IMMUNOTECH (A Beckman Coulter Company)
130, av.de Lattre de Tassigny—BP 177
13276 Marseille Cedex 09—France Tèl. (33) 4 91 17 27 00
¤
Distributor and Refer to attached list, Document ID: 472050, for local distributor and
Emergency Phone No. emergency phone numbers.
Section 2 Composition and Information on Ingredients
Hazardous Ingredients: None
Section 3 Hazards Identification
Emergency Overview
Colorless; Transparent; Lyophilized—Liquid after reconstitution.; Odorless
Nonflammable aqueous solution.
Does not meet EU, OSHA or WHMIS criteria for hazardous materials.
Contains material of animal origin.
Physical Hazards No physical hazards were determined from a review of available literature.
Potential Health This product does not meet EU, OSHA or WHMIS criteria for hazardous materials.
Effects Summary However, it does contain material of animal origin and should be considered
potentially infectious.
Product Hazard EU: WHMIS: US OSHA:
Classifications Not applicable Not applicable Not applicable
Beckman Coulter Safety Flammability (Section V): 0 Code
Rating Health (Section XI): 1 0=none
Reactivity with Water (Section X): 0 1=slight
Contact (Section VIII): 1 2=caution
3=severe
Section 4 First Aid Measures
Inhalation If product is inhaled, move exposed individual to fresh air. If individual is not
breathing, begin artificial respiration immediately and obtain medical attention.
Eye Contact If product enters eyes, wash eyes gently under running water for 15 minutes or
longer, making sure that the eyelids are held open. If pain or irritation occur, obtain
medical attention.
Allergenicity Kit Doc. ID: A17116-75 AA Page 17 of 30
IgE Antibody
Section 4 First Aid Measures (Continued)
Skin Contact Remove any contaminated clothing. Wash affected area with plenty of soap and
water. Use disinfectant if possible.
Ingestion If ingested, wash mouth out with water. If irritation or discomfort occurs, seek medical
attention.
Section 5 Fire Fighting Measures
Flash Point Not applicable
Flammable Limits Not applicable
Autoignition Temp. Not applicable
Extinguishing Media Use extinguishing media suitable for surrounding fire.
Special Fire and No special hazards determined.
Explosion Hazards
Hazardous Combustion Due to the composition and volume of this product, combustion products generated
Products from it are not expected to present a significant hazard.
Protective Equipment Self-contained breathing apparatus is recommended for firefighters in all chemical fire
for Firefighters situations.
Section 6 Accidental Release Measures
Personal Precautions This product contains a material of biological origin. Use universal precautions during
clean up procedures.
Spill and Leak As a precautionary measure, treat spilled material with a 1:10 bleach/water solution.
Procedures Absorb liquid and place in container suitable for disposal. Avoid generation of
aerosols during clean up. Comply with applicable waste disposal regulations.
Environmental Contain spill to prevent migration.
Precautions
Section 7 Handling and Storage
Handling Precautions This product should be handled as though capable of transmitting infectious diseases.
Universal precautions should be followed when using this product.
Recommended Storage Keep away from incompatible material.
Conditions To maintain efficacy, store according to the instructions in the product labeling.
Section 8 Exposure Controls and Personal Protection
Exposure Limits
US OSHA: None established
ACGIH: None established
DFG MAK: None established
Engineering Controls No special engineering controls are required. Use with good general ventilation.
Respiratory Protection Under normal conditions, the use of this product should not require respiratory
protection.
Allergenicity Kit Doc. ID: A17116-75 AA Page 18 of 30
IgE Antibody
Section 8 Exposure Controls and Personal Protection (Continued)
Eye Protection Safety glasses or chemical goggles should be worn to prevent eye contact.
Skin Protection Impervious gloves, such as latex or equivalent, should be worn to prevent skin
contact.
Section 9 Physical and Chemical Properties
Physical State Lyophilized—Liquid after reconstitution.
Color Colorless
Transparency Transparent
Odor Odorless
Odor Threshold Not applicable
pH 7.25
Boiling Point Not available
Melting Point Not available
Specific Gravity 1.005 @20°C
Vapor Pressure Not available
Vapor Density Not available
Evaporation Rate Not available
Solubility
Water Miscible
Organic Not available
Section 10 Stability and Reactivity
Stability Stable under normal temperatures and pressures.
Hazardous Strong acids
Incompatibilities Strong bases
Strong oxidizers
Hazardous No decomposition products posing significant hazards would be expected from this
Decomposition Products product (a dilute aqueous solution).
Conditions to Avoid Avoid contact with incompatible materials.
Section 11 Toxicological Information
Toxicity Data Not applicable
for Hazardous Ingredients
Primary Routes Common routes of entry include inhalation, ingestion and eye/skin contact. Specific
of Exposure paths of concern for potentially infectious materials are skin puncture, contact with
broken skin, contact with mucous membranes and inhalation of aerosolized material.
Potential Effects of This product contains materials of animal origin and should be considered potentially
Acute Exposure infectious. No other health hazards were identified from a review of available
literature.
Allergenicity Kit Doc. ID: A17116-75 AA Page 19 of 30
IgE Antibody
Section 11 Toxicological Information (Continued)
Potential Effects of Effects are similar to those for acute exposure.
Chronic Exposure
Symptoms of No specific symptoms identified.
Overexposure
Carcinogenicity No ingredients in this product are listed as carcinogens by ACGIH, IARC, NTP, OSHA
or 67/548/EEC Annex I.
Other Effects None identified.
Conditions Aggravated None identified.
by Exposure
Section 12 Ecological Information
Ecotoxicity No information available.
Biodegradability No information available.
Mobility No information available.
Section 13 Disposal Considerations
Waste Disposal Dispose of waste product, unused product and contaminated packaging in compliance
with federal, state and local regulations. If unsure of the applicable requirements,
contact the authorities for information.
Section 14 Transport Information
Transportation of this product is not regulated under ICAO, IMDG, US DOT, European ADR or Canadian TDG.
Section 15 Regulatory Information
US Federal and State Regulations
SARA 313 No ingredients listed
CERCLA RG’s, No ingredients listed
40 CFR 302.4
California Proposition 65 No ingredients listed
Massachusetts MSL No ingredients listed
New Jersey Dept. of No ingredients listed
Health RTK List
Pennsylvania RTK No ingredients listed
EU Labeling Classification
Preparation not classified.
Allergenicity Kit Doc. ID: A17116-75 AA Page 20 of 30
IgE Antibody
Section 15 Regulatory Information (Continued)
Canada
This product does not meet WHMIS criteria for hazardous materials.
PIN: Not applicable
Ingredients on Ingredient None
Disclosure List:
Ingredients with unknown None
toxicological properties:
Section 16 Other Information
For further information, please contact your local Beckman Coulter representative.
WHILE BECKMAN COULTER, INC. BELIEVES THE INFORMATION CONTAINED HEREIN IS VALID AND ACCURATE, BECKMAN COULTER MAKES NO WARRANTY OR
REPRESENTATION AS TO ITS VALIDITY, ACCURACY, OR CURRENCY. BECKMAN COULTER SHALL NOT BE LIABLE OR OTHERWISE RESPONSIBLE IN ANY WAY FOR USE
OF EITHER THIS INFORMATION OR MATERIALS TO WHICH IT APPLIES. DISPOSAL OF HAZARDOUS MATERIALS MAY BE SUBJECT TO LOCAL LAWS OR REGULATIONS.
Printed in U.S.A.
Page 21 of 30
@Beckman
Coulter® MATERIAL SAFETY DATA SHEET
Section 1 Company and Product Identification
Fixative Solution
Product Name Allergenicity Kit
Doc. ID A17116-75 AA
Issued (year/month/day) 2004/06/01
Part Number Component of P/N A17116
Manufacturer Distributed by Beckman Coulter, Inc. for
IMMUNOTECH (A Beckman Coulter Company)
130, av.de Lattre de Tassigny—BP 177
13276 Marseille Cedex 09—France Tèl. (33) 4 91 17 27 00
¤
Distributor and Refer to attached list, Document ID: 472050, for local distributor and
Emergency Phone No. emergency phone numbers.
Section 2 Composition and Information on Ingredients
Hazardous Ingredients: Meets Hazardous Criteria:
Chemical Name CAS # % by wt. EU US OSHA WHMIS
<10%
Formaldehyde 50-00-0 Carc. category Yes Yes
3;
T;R23/24/25-34-
40-43
See Section 15 Regulatory Information for additional information on hazard classifications.
Section 3 Hazards Identification
Emergency Overview
Colorless; Transparent; Liquid; Odorless
Nonflammable aqueous solution.
Harmful by inhalation, in contact with skin and if swallowed.
May cause irritation of skin, eyes, mucous
membranes and upper respiratory tract.
Suspect carcinogen.
Physical Hazards No physical hazards were determined from a review of available literature.
Potential Health May cause eye, skin and respiratory tract irritation or burns and central nervous
Effects Summary system depression with headache, dizziness, nausea and unconsciousness. Potential
cancer hazard.
See Section 11 Toxicological Information for more detailed health information.
Product Hazard EU: WHMIS: US OSHA:
Classifications Xn;R20/21/22-36/37/38- D2A; D2B Hazardous
40-43
Beckman Coulter Safety Flammability (Section V): 0 Code
Rating Health (Section XI): 2 0=none
Reactivity with Water (Section X): 0 1=slight
Contact (Section VIII): 2 2=caution
3=severe
Allergenicity Kit Doc. ID: A17116-75 AA Page 22 of 30
Fixative Solution
Section 4 First Aid Measures
Inhalation If product is inhaled, move exposed individual to fresh air. If individual is not
breathing, begin artificial respiration immediately and obtain medical attention.
Eye Contact If product enters eyes, wash eyes gently under running water for 15 minutes or
longer, making sure that the eyelids are held open. If pain or irritation occur, obtain
medical attention.
Skin Contact In case of skin contact, flush with copious amounts of water for at least 15 minutes.
Remove contaminated clothing and shoes. If pain or irritation occur, obtain medical
attention.
Ingestion If ingested, wash mouth out with water. If irritation or discomfort occurs, seek medical
attention.
Section 5 Fire Fighting Measures
Flash Point Not applicable
Flammable Limits Not applicable
Autoignition Temp. Not applicable
Extinguishing Media Use extinguishing media suitable for surrounding fire.
Special Fire and No special hazards determined.
Explosion Hazards
Hazardous Combustion Due to the composition and volume of this product, combustion products generated
Products from it are not expected to present a significant hazard.
Protective Equipment Self-contained breathing apparatus is recommended for firefighters in all chemical fire
for Firefighters situations.
Section 6 Accidental Release Measures
Personal Precautions Use good laboratory procedures; avoid eye and skin contact.
Spill and Leak Absorb spilled material with an appropriate inert, non-flammable absorbent and
Procedures dispose according to local regulations.
Environmental Contain spill to prevent migration.
Precautions
Section 7 Handling and Storage
Handling Precautions No special precautions are necessary; use good laboratory procedures.
Recommended Storage To maintain efficacy, store according to the instructions in the product labeling.
Conditions
Section 8 Exposure Controls and Personal Protection
Exposure Limits
US OSHA: None established
ACGIH:
Formaldehyde 0.3 ppm Ceiling
Allergenicity Kit Doc. ID: A17116-75 AA Page 23 of 30
Fixative Solution
Section 8 Exposure Controls and Personal Protection (Continued)
DFG MAK:
Formaldehyde 0.3 ppm MAK; 0.37 mg/m3 MAK; 0.6 ppm Peak; 0.74 mg/m3 Peak (during exposure to
mixtures it should be ensured that irritant effects do not occur)
Engineering Controls No special engineering controls are required. Use with good general ventilation.
Respiratory Protection Under normal conditions, the use of this product should not require respiratory
protection. If overexposure should occur and ventilation is not adequate to maintain
airborne concentrations at acceptable levels, the use of respiratory protection should
be evaluated by a qualified professional.
Eye Protection Safety glasses or chemical goggles should be worn to prevent eye contact.
Skin Protection Impervious gloves, such as latex or equivalent, should be worn to prevent skin
contact.
Section 9 Physical and Chemical Properties
Physical State Liquid
Color Colorless
Transparency Transparent
Odor Odorless
Odor Threshold Formaldehyde no geometric mean air odor threshold
pH 7.5
Boiling Point Not available
Melting Point Not available
Specific Gravity 1.0 @20°C
Vapor Pressure Not available
Vapor Density Not available
Evaporation Rate Not available
Solubility
Water Miscible
Organic Not available
Section 10 Stability and Reactivity
Stability Stable in closed containers under normal temperatures and pressures.
Hazardous Strong acids
Incompatibilities Strong bases
Strong oxidizers
Hazardous Formaldehyde
Decomposition Products
Conditions to Avoid Avoid contact with incompatible materials.
Allergenicity Kit Doc. ID: A17116-75 AA Page 24 of 30
Fixative Solution
Section 11 Toxicological Information
Toxicity Data
for Hazardous Ingredients
Formaldehyde Inhalation LC50 Mouse: 454 mg/m3/4H; Oral LD50 Rat: 100 mg/kg; Oral
LD50 Mouse: 42 mg/kg; Dermal LD50 Rabbit: 270 µL/kg
Primary Routes The most likely routes of exposure are skin and eye contact.
of Exposure
Potential Effects of May cause irritation or burning of skin and eyes by contact. Inhalation and ingestion
Acute Exposure of large volumes may cause burning of mucous membrane, respiratory irritation.
Potential Effects of Prolonged and/or repeated exposure may result in conjunctivitis, dermatitis and
Chronic Exposure allergic reactions.
Symptoms of Symptoms may include redness and itching or burning of the skin and eyes, and
Overexposure irritation or burning sensation of the upper respiratory tract with coughing and difficulty
in breathing.
Carcinogenicity Formaldehyde is listed with OSHA as a carcinogen; NTP as Anticipated Human
Carcinogen; IARC as Group 2A with Animal Sufficient Evidence and Human Limited
Evidence; ACGIH as Group A2 Suspected Human Carcinogen and EU as Category 3
Carcinogen.
Other Effects None identified.
Conditions Aggravated Individuals with skin, eye, or respiratory tract disorders may find these conditions
by Exposure aggravated by exposure to this product.
Section 12 Ecological Information
Ecotoxicity Toxic to fish and other water organisms.
Biodegradability No information available.
Mobility No information available.
Section 13 Disposal Considerations
Waste Disposal Dispose of waste product, unused product and contaminated packaging in compliance
with federal, state and local regulations. If unsure of the applicable requirements,
contact the authorities for information.
Section 14 Transport Information
Transportation of this product is not regulated under ICAO, IMDG, US DOT, European ADR or Canadian TDG.
Section 15 Regulatory Information
US Federal and State Regulations
SARA 313 Formaldehyde is subject to reporting requirements of Section 313, Title III of SARA.
CERCLA RG’s, Formaldehyde is listed.
40 CFR 302.4
Allergenicity Kit Doc. ID: A17116-75 AA Page 25 of 30
Fixative Solution
Section 15 Regulatory Information (Continued)
US Federal and State Regulations
California Proposition 65 Formaldehyde has been identified by the State of California to cause cancer. The State
of California has adopted a regulation which requires a warning be given to individuals
who may be exposed to chemicals identified by the State to cause cancer or reproductive
harm. Accordingly, Beckman Coulter advises you of the following warning:
WARNING: This product contains a chemical known to the State of California to cause
cancer.
Massachusetts MSL Formaldehyde is listed.
New Jersey Dept. of Formaldehyde is listed.
Health RTK List
Pennsylvania RTK Formaldehyde is listed.
EU Labeling Classification
Classification Risk and Safety Phrases
Xn R20/21/22 Harmful by inhalation, in contact with skin and if swallowed.
R36/37/38 Irritating to eyes, respiratory system and skin.
Harmful
R40 Limited evidence of a carcinogenic effect
R43 May cause sensitization by skin contact.
Canada
WHMIS Classification: D2A—Poisonous and Infectious Material: Division 2—Other Toxic Effects: Very Toxic
(Carcinogenicity)
D2B—Poisonous and Infectious Material: Division 2—Other Toxic Effects: Toxic (Chronic
Toxic Effects)
PIN: Not applicable
Ingredients on Ingredient Formaldehyde
Disclosure List:
Ingredients with unknown None
toxicological properties:
Section 16 Other Information
For further information, please contact your local Beckman Coulter representative.
WHILE BECKMAN COULTER, INC. BELIEVES THE INFORMATION CONTAINED HEREIN IS VALID AND ACCURATE, BECKMAN COULTER MAKES NO WARRANTY OR
REPRESENTATION AS TO ITS VALIDITY, ACCURACY, OR CURRENCY. BECKMAN COULTER SHALL NOT BE LIABLE OR OTHERWISE RESPONSIBLE IN ANY WAY FOR USE
OF EITHER THIS INFORMATION OR MATERIALS TO WHICH IT APPLIES. DISPOSAL OF HAZARDOUS MATERIALS MAY BE SUBJECT TO LOCAL LAWS OR REGULATIONS.
Printed in U.S.A.
Page 26 of 30
@Beckman
Coulter® MATERIAL SAFETY DATA SHEET
Section 1 Company and Product Identification
VersaLyse Lysing
Product Name
Solution Allergenicity Kit
Doc. ID A17116-75 AA
Issued (year/month/day) 2004/06/01
Part Number Component of P/N A17116
Manufacturer Distributed by Beckman Coulter, Inc. for
IMMUNOTECH (A Beckman Coulter Company)
130, av.de Lattre de Tassigny—BP 177
13276 Marseille Cedex 09—France Tèl. (33) 4 91 17 27 00
¤
Distributor and Refer to attached list, Document ID: 472050, for local distributor and
Emergency Phone No. emergency phone numbers.
Section 2 Composition and Information on Ingredients
Hazardous Ingredients: Meets Hazardous Criteria:
Chemical Name CAS # % by wt. EU US OSHA WHMIS
<2%
Pyrrolidine 123-75-1 No Yes Yes
See Section 15 Regulatory Information for additional information on hazard classifications.
Section 3 Hazards Identification
Emergency Overview
Colorless; Clear; Liquid; Slight odor
Nonflammable aqueous solution.
Skin, eye and respiratory tract irritant.
Physical Hazards No physical hazards were determined from a review of available literature.
Potential Health Exposure may result in irritation of skin, eyes, and mucous membranes.
Effects Summary
See Section 11 Toxicological Information for more detailed health information.
Product Hazard EU: WHMIS: US OSHA:
Classifications Not applicable D2B Hazardous
Beckman Coulter Safety Flammability (Section V): 0 Code
Rating Health (Section XI): 1 0=none
Reactivity with Water (Section X): 0 1=slight
Contact (Section VIII): 2 2=caution
3=severe
Section 4 First Aid Measures
Inhalation If product is inhaled, move exposed individual to fresh air. If individual is not
breathing, begin artificial respiration immediately and obtain medical attention.
Allergenicity Kit Doc. ID: A17116-75 AA Page 27 of 30
VersaLyse Lysing Solution
Section 4 First Aid Measures (Continued)
Eye Contact If product enters eyes, wash eyes gently under running water for 15 minutes or
longer, making sure that the eyelids are held open. If pain or irritation occur, obtain
medical attention.
Skin Contact In case of skin contact, flush with copious amounts of water for at least 15 minutes.
Remove contaminated clothing and shoes. If pain or irritation occur, obtain medical
attention.
Ingestion If ingested, wash mouth out with water. If irritation or discomfort occurs, seek medical
attention.
Section 5 Fire Fighting Measures
Flash Point Not applicable
Flammable Limits Not applicable
Autoignition Temp. Not applicable
Extinguishing Media Use extinguishing media suitable for surrounding fire.
Special Fire and None identified.
Explosion Hazards
Hazardous Combustion Due to the composition and volume of this product, combustion products generated
Products from it are not expected to present a significant hazard.
Protective Equipment Self-contained breathing apparatus is recommended for firefighters.
for Firefighters
Section 6 Accidental Release Measures
Personal Precautions Avoid skin contact. Use good laboratory procedures.
Spill and Leak Absorb spilled material with an appropriate inert, non-flammable absorbent and
Procedures dispose according to local regulations.
Environmental Contain spill to prevent migration.
Precautions
Section 7 Handling and Storage
Handling Precautions Use good laboratory procedures; avoid eye and skin contact.
Recommended Storage Keep away from incompatible material.
Conditions To maintain efficacy, store according to the instructions in the product labeling.
Section 8 Exposure Controls and Personal Protection
Exposure Limits
US OSHA: None established
ACGIH: None established
DFG MAK:
Pyrrolidine Skin Absorber
Allergenicity Kit Doc. ID: A17116-75 AA Page 28 of 30
VersaLyse Lysing Solution
Section 8 Exposure Controls and Personal Protection (Continued)
Engineering Controls No special engineering controls are required. Use with good general ventilation.
Respiratory Protection Under normal conditions, the use of this product should not require respiratory
protection. If overexposure should occur and ventilation is not adequate to maintain
airborne concentrations at acceptable levels, the use of respiratory protection should
be evaluated by a qualified professional.
Eye Protection Safety glasses or chemical goggles should be worn to prevent eye contact.
Skin Protection Impervious gloves, such as latex or equivalent, should be worn to prevent skin
contact.
Section 9 Physical and Chemical Properties
Physical State Liquid
Color Colorless
Transparency Clear
Odor Slight odor
Odor Threshold Not applicable
pH 7.2?7.9
Boiling Point Not available
Melting Point Not available
Specific Gravity 1 @20°C
Vapor Pressure Not available
Vapor Density Not available
Evaporation Rate Not available
Solubility
Water Miscible
Organic Not available
Section 10 Stability and Reactivity
Stability Stable under normal temperatures and pressures.
Hazardous Strong oxidizers
Incompatibilities Strong acids
Strong bases
Hazardous No decomposition products posing significant hazards would be expected from this
Decomposition Products product (a dilute aqueous solution).
Conditions to Avoid Keep away from incompatible material.
Section 11 Toxicological Information
Toxicity Data
for Hazardous Ingredients
Pyrrolidine Inhalation LC50 Mouse: 1300 mg/m3/2H; Oral LD50 Rat: 300 mg/kg; Oral
LD50 Mouse: 450 mg/kg
Allergenicity Kit Doc. ID: A17116-75 AA Page 29 of 30
VersaLyse Lysing Solution
Section 11 Toxicological Information (Continued)
Primary Routes The most likely routes of exposure are skin, eye contact and inhalation.
of Exposure
Potential Effects of Skin and eye contact may cause redness and pain. Inhalation may result in coughing,
Acute Exposure respiratory irritation, dyspnea, and pulmonary edema.
Potential Effects of Repeat and prolonged contact with skin and eyes may result in dermatitis and
Chronic Exposure conjunctivitis. Prolonged exposure by inhalation may cause mucous membrane
irritation.
Symptoms of Symptoms may include redness and itching or burning of the skin and eyes, and
Overexposure irritation or burning sensation of the upper respiratory tract with coughing and difficulty
in breathing.
Carcinogenicity No ingredients in this product are listed as carcinogens by ACGIH, IARC, NTP, OSHA
or 67/548/EEC Annex I.
Other Effects None identified.
Conditions Aggravated Individuals with eye and skin disorders may find these conditions aggravated by
by Exposure exposure to this product.
Section 12 Ecological Information
Ecotoxicity Toxic to fish and other water organisms.
Biodegradability No information available.
Mobility No information available.
Section 13 Disposal Considerations
Waste Disposal Dispose of waste product, unused product and contaminated packaging in compliance
with federal, state and local regulations. If unsure of the applicable requirements,
contact the authorities for information.
Section 14 Transport Information
Transportation of this product is not regulated under ICAO, IMDG, US DOT, European ADR or Canadian TDG.
Section 15 Regulatory Information
US Federal and State Regulations
SARA 313 Hydrochloric Acid is subject to reporting requirements of Section 313, Title III of SARA.
CERCLA RG’s, Hydrochloric Acid is listed.
40 CFR 302.4
California Proposition 65 No ingredients listed
Massachusetts MSL Pyrrolidine is listed.
Hydrochloric Acid is listed.
New Jersey Dept. of Pyrrolidine is listed.
Health RTK List Hydrochloric Acid is listed.
Pennsylvania RTK Pyrrolidine is listed.
Hydrochloric Acid is listed.
Allergenicity Kit Doc. ID: A17116-75 AA Page 30 of 30
VersaLyse Lysing Solution
Section 15 Regulatory Information (Continued)
EU Labeling Classification
Preparation not classified.
Canada
WHMIS Classification: D2B—Poisonous and Infectious Material: Division 2—Other Toxic Effects: Toxic (Skin
Irritation)
D2B—Poisonous and Infectious Material: Division 2—Other Toxic Effects: Toxic (Eye
Irritation)
PIN: Not applicable
Ingredients on Ingredient Hydrochloric Acid
Disclosure List:
Ingredients with unknown None
toxicological properties:
Section 16 Other Information
For further information, please contact your local Beckman Coulter representative.
WHILE BECKMAN COULTER, INC. BELIEVES THE INFORMATION CONTAINED HEREIN IS VALID AND ACCURATE, BECKMAN COULTER MAKES NO WARRANTY OR
REPRESENTATION AS TO ITS VALIDITY, ACCURACY, OR CURRENCY. BECKMAN COULTER SHALL NOT BE LIABLE OR OTHERWISE RESPONSIBLE IN ANY WAY FOR USE
OF EITHER THIS INFORMATION OR MATERIALS TO WHICH IT APPLIES. DISPOSAL OF HAZARDOUS MATERIALS MAY BE SUBJECT TO LOCAL LAWS OR REGULATIONS.
Printed in U.S.A.
|