Page 1 of 11
@Beckman
CoulterTM Kit MSDS
Doc. ID: IM2393-75: Rev. AA
Product Information
Product Name UltraTech AEC
Doc. ID IM2393-75 AA
Part Number IM2393 Issued (year/month/day) 2007/07/10
Series Name: UltraTech
Additional Product For Research Use Only. See product literature for details.
Information:
Components
Description
AEC concentrated
Substrate Buffer
Transport Information
Transportation of this product is not regulated under ICAO, IMDG, US DOT, European ADR or Canadian TDG.
�2007 Beckman Coulter, Inc.
Global MSDS � English
Page 2 of 11
@Beckman
CoulterTM MATERIAL SAFETY DATA SHEET
Section 1 Company and Product Identiï¬cation
Product Name AEC concentrated
UltraTech AEC
Doc. ID IM2393-75 AA
Part Number Component of P/N IM2393
Issued (year/month/day) 2007/07/10
Series Name UltraTech
Manufacturer Distributed by Beckman Coulter, Inc. for
IMMUNOTECH (A Beckman Coulter Company)
130, av.de Lattre de Tassigny—BP 177
13276 Marseille Cedex 09—France Tèl. (33) 4 91 17 27 00
ECREP Address:
Beckman Coulter Ireland, Inc.
Mervue Business Park,
Mervue, Galway, Ireland 353 91 774068
¤
Distributor and Refer to attached list, Document ID: 472050, for local distributor and
Emergency Phone No. emergency phone numbers.
Section 2 Composition and Information on Ingredients
Hazardous Ingredients: Meets Hazardous Criteria:
Chemical Name CAS # % by wt. EU US OSHA WHMIS
>25%
N,N-Dimethylformamide 68-12-2 Toxic for Yes Yes
Reproduction,
category 2;
T;R61-20/21-36
<3%
3-Amino-9-Ethylcarbazole (AEC) 132-32-1 T;R25-40 Yes Yes
Carc. category
3;
See Section 15 Regulatory Information for additional information on hazard classiï¬cations.
Section 3 Hazards Identiï¬cation
Emergency Overview
Colorless; Clear; Liquid; Fishy
Nonflammable solution.
CNS depressant. Eye, skin and respiratory tract irritant.
Suspect carcinogen.
Physical Hazards Flammable component of solution may present ï¬re hazard at elevated temperatures.
Potential Health Contact may cause irritation to the eyes, skin and mucous membranes. May be
Effects Summary absorbed through the skin. Vapors may cause irritation to the eyes and respiratory
tract and nervous system depression. Swallowing may cause gastrointestinal irritation
and nervous system effects.
See Section 11 Toxicological Information for more detailed health information.
UltraTech AEC Doc. ID: IM2393-75 AA Page 3 of 11
AEC concentrated
Section 3 Hazards Identiï¬cation (Continued)
Product Hazard EU: WHMIS: US OSHA:
Classiï¬cations T;R20/21-22-40-61 D2A; D2B Hazardous
Beckman Coulter Safety Flammability (Section V): 1 Code
Rating Health (Section XI): 2 0=none
Reactivity with Water (Section X): 0 1=slight
Contact (Section VIII): 2 2=caution
3=severe
Section 4 First Aid Measures
Inhalation If product is inhaled, move exposed individual to fresh air. If individual is not
breathing, begin artiï¬cial respiration immediately and obtain medical attention.
Eye Contact If product enters eyes, wash eyes gently under running water for 15 minutes or
longer, making sure that the eyelids are held open. If pain or irritation occur, obtain
medical attention.
Skin Contact In case of skin contact, flush with copious amounts of water for at least 15 minutes.
Remove contaminated clothing and shoes. If pain or irritation occur, obtain medical
attention.
Ingestion If ingested, wash mouth out with water. If irritation or discomfort occurs, seek medical
attention.
Section 5 Fire Fighting Measures
Flash Point Not applicable
Flammable Limits Not available
Autoignition Temp. Not applicable
Extinguishing Media Dry chemical, carbon dioxide or alcohol-resistant foam.
Special Fire and None identiï¬ed.
Explosion Hazards
Hazardous Combustion Combustion products may include oxides of carbon and nitrogen.
Products
Protective Equipment Self-contained breathing apparatus is recommended for ï¬reï¬ghters in all chemical ï¬re
for Fireï¬ghters situations.
Section 6 Accidental Release Measures
Personal Precautions Use good laboratory procedures; avoid eye and skin contact.
Spill and Leak Absorb spilled material with an appropriate inert, non-flammable absorbent and
Procedures dispose according to local regulations.
Environmental Contain spill to prevent migration.
Precautions
Section 7 Handling and Storage
Handling Precautions Use good laboratory procedures; avoid eye and skin contact.
Recommended Storage Keep away from excessive heat, sparks or open flame.
Conditions Keep away from incompatible material (see Section 10).
To maintain efï¬cacy, store according to the instructions in the product labeling.
UltraTech AEC Doc. ID: IM2393-75 AA Page 4 of 11
AEC concentrated
Section 8 Exposure Controls and Personal Protection
Exposure Limits
US OSHA:
N,N- 10 ppm TWA; 30 mg/m3 TWA; prevent or reduce skin
Dimethylformamide absorption
ACGIH:
N,N- Skin—potential signiï¬cant contribution to overall exposure
Dimethylformamide by the cutaneous route; 10 ppm TWA
DFG MAK:
N,N- 5 ppm MAK; 15 mg/m3 MAK; 20 ppm Peak; 60 mg/m3 Peak; skin notation
Dimethylformamide
Engineering Controls No special engineering controls are required. Use with good general ventilation.
Respiratory Protection Under normal conditions, the use of this product should not require respiratory
protection. If overexposure should occur and ventilation is not adequate to maintain
airborne concentrations at acceptable levels, the use of respiratory protection should
be evaluated by a qualiï¬ed professional.
Eye Protection Safety glasses or chemical goggles should be worn to prevent eye contact.
Skin Protection Impervious gloves, such as Nitrile or equivalent, should be worn to prevent skin
contact.
Section 9 Physical and Chemical Properties
Physical State Liquid
Color Colorless
Transparency Clear
Odor Fishy
Odor Threshold N,N-Dimethylformamide no geometric mean air odor threshold
pH Not available
Boiling Point Not available
Melting Point Not available
Speciï¬c Gravity 1 @20°C
Vapor Pressure Not available
Vapor Density Not available
Evaporation Rate Not available
Solubility
Water Miscible
Organic Not available
Section 10 Stability and Reactivity
Stability Stable under normal temperatures and pressures.
UltraTech AEC Doc. ID: IM2393-75 AA Page 5 of 11
AEC concentrated
Section 10 Stability and Reactivity (Continued)
Hazardous Strong oxidizers
Incompatibilities Strong acids
Hazardous Thermal decomposition products may include small amounts of oxides of carbon and
Decomposition Products nitrogen.
Conditions to Avoid Avoid contact with heat, ignition sources and incompatible materials.
Section 11 Toxicological Information
Toxicity Data
for Hazardous Ingredients
Inhalation LC50 Rat: >5.9 mg/L/4H; Oral LD50 Rat: 2200 mg/kg; Dermal LD50
N,N-Dimethylformamide
Rabbit: 1500 mg/kg
Primary Routes Eye contact, ingestion, inhalation, and skin contact.
of Exposure
Potential Effects of Eye and skin contact may cause moderate to severe irritation. Inhalation of mists may
Acute Exposure cause irritation to the mucous membranes and respiratory tract. Ingestion may cause
mucous membrane and gastrointestinal irritation with nausea, vomiting and abdominal
pain.
Potential Effects of Frequent or continued inhalation of vapors may produce nausea, headache, and
Chronic Exposure central nervous system depression. Chronic skin exposure may defat the skin and
result in dermatitis. Chronic ingestion may result in diarrhea, twitching, loss of
memory, and reproductive effects.
Symptoms of Symptoms of overexposure may include: redness, burning and watering of the eyes;
Overexposure dry, red, cracked skin; coughing and difï¬cult breathing; nausea and vomiting.
Carcinogenicity No ingredients in this product are listed as carcinogens by ACGIH, IARC, NTP, OSHA
or 67/548/EEC Annex I.
Other Effects Reproductive effects have been reported.
Suspect carcinogen.
Conditions Aggravated Individuals with skin, eye, cardiovascular, blood, respiratory and nervous system
by Exposure disorders may ï¬nd these conditions aggravated by exposure to this product.
Section 12 Ecological Information
Ecotoxicity N,N-Dimethylformamide: 96 Hr LC50 Lepomis macrochirus: 6300 mg/L; 96 Hr LC50
Oncorhynchus mykiss: 9800 mg/L [flow-through]; 96 Hr LC50 Oncorhynchus mykiss:
1020 mg/L [static]; 96 Hr LC50 Pimephales promelas: 10410 mg/L [flow-through]
Biodegradability No information available.
Mobility No information available.
Section 13 Disposal Considerations
Waste Disposal Dispose of waste product, unused product and contaminated packaging in compliance
with federal, state and local regulations. If unsure of the applicable requirements,
contact the authorities for information.
Section 14 Transport Information
Transportation of this product is not regulated under ICAO, IMDG, US DOT, European ADR or Canadian TDG.
UltraTech AEC Doc. ID: IM2393-75 AA Page 6 of 11
AEC concentrated
Section 15 Regulatory Information
US Federal and State Regulations
SARA 313 N,N-Dimethylformamide is subject to reporting requirements of Section 313, Title III of
SARA.
CERCLA RG’s, N,N-Dimethylformamide is listed.
40 CFR 302.4
California Proposition 65 No ingredients listed
Massachusetts MSL N,N-Dimethylformamide is listed.
New Jersey Dept. of N,N-Dimethylformamide is listed.
Health RTK List
Pennsylvania RTK N,N-Dimethylformamide is listed.
EU Labeling Classiï¬cation
Classiï¬cation Risk and Safety Phrases
T R20/21 Harmful by inhalation and in contact with skin.
R22 Harmful if swallowed.
Toxic
R40 Limited evidence of a carcinogenic effect
R61 May cause harm to unborn child.
S45 In case of accident or if you feel unwell, seek medical advice immediately (show
the label where possible).
S53 Avoid exposure—obtain special instructions before use.
Canada
WHMIS Classiï¬cation: D2B—Poisonous and Infectious Material: Division 2—Other Toxic Effects: Toxic (Chronic
Toxic Effects)
D2A—Poisonous and Infections Material: Division 2—Other Toxic Effects: Very Toxic
(Teratogenicity and Embryotoxicity)
PIN: Not applicable
Ingredients on Ingredient N,N-Dimethylformamide
Disclosure List:
Ingredients with unknown None
toxicological properties:
Section 16 Other Information
For further information, please contact your local Beckman Coulter representative.
WHILE BECKMAN COULTER, INC. BELIEVES THE INFORMATION CONTAINED HEREIN IS VALID AND ACCURATE, BECKMAN COULTER MAKES NO WARRANTY OR
REPRESENTATION AS TO ITS VALIDITY, ACCURACY, OR CURRENCY. BECKMAN COULTER SHALL NOT BE LIABLE OR OTHERWISE RESPONSIBLE IN ANY WAY FOR USE
OF EITHER THIS INFORMATION OR MATERIALS TO WHICH IT APPLIES. DISPOSAL OF HAZARDOUS MATERIALS MAY BE SUBJECT TO LOCAL LAWS OR REGULATIONS.
Printed in U.S.A.
Page 7 of 11
@Beckman
CoulterTM MATERIAL SAFETY DATA SHEET
Section 1 Company and Product Identiï¬cation
Product Name Substrate Buffer
UltraTech AEC
Doc. ID IM2393-75 AA
Part Number Component of P/N IM2393
Issued (year/month/day) 2007/07/10
Series Name UltraTech
Manufacturer Distributed by Beckman Coulter, Inc. for
IMMUNOTECH (A Beckman Coulter Company)
130, av.de Lattre de Tassigny—BP 177
13276 Marseille Cedex 09—France Tèl. (33) 4 91 17 27 00
ECREP Address:
Beckman Coulter Ireland, Inc.
Mervue Business Park,
Mervue, Galway, Ireland 353 91 774068
¤
Distributor and Refer to attached list, Document ID: 472050, for local distributor and
Emergency Phone No. emergency phone numbers.
Section 2 Composition and Information on Ingredients
Hazardous Ingredients: None
Section 3 Hazards Identiï¬cation
Emergency Overview
Colorless; Clear; Liquid; Odorless
Nonflammable aqueous solution.
Does not meet EU, OSHA or WHMIS criteria for hazardous materials.
Physical Hazards No physical hazards were determined from a review of available literature.
Potential Health This product does not meet EU, OSHA or WHMIS criteria for hazardous materials.
Effects Summary
Product Hazard EU: WHMIS: US OSHA:
Classiï¬cations Not applicable Not applicable Not applicable
Beckman Coulter Safety Flammability (Section V): 0 Code
Rating Health (Section XI): 0 0=none
Reactivity with Water (Section X): 0 1=slight
Contact (Section VIII): 1 2=caution
3=severe
Section 4 First Aid Measures
Inhalation If product is inhaled, move exposed individual to fresh air. If individual is not
breathing, begin artiï¬cial respiration immediately and obtain medical attention.
Eye Contact If product enters eyes, wash eyes gently under running water for 15 minutes or
longer, making sure that the eyelids are held open. If pain or irritation occur, obtain
medical attention.
UltraTech AEC Doc. ID: IM2393-75 AA Page 8 of 11
Substrate Buffer
Section 4 First Aid Measures (Continued)
Skin Contact In case of skin contact, flush with copious amounts of water for at least 15 minutes. If
pain or irritation occur, obtain medical attention.
Ingestion If ingested, wash mouth out with water. If irritation or discomfort occurs, seek medical
attention.
Section 5 Fire Fighting Measures
Flash Point Not applicable
Flammable Limits Not applicable
Autoignition Temp. Not applicable
Extinguishing Media Use extinguishing media suitable for surrounding ï¬re.
Special Fire and None identiï¬ed.
Explosion Hazards
Hazardous Combustion Combustion products posing signiï¬cant hazards are not expected from the small
Products volume of this product present during normal use.
Protective Equipment Self-contained breathing apparatus is recommended for ï¬reï¬ghters in all chemical ï¬re
for Fireï¬ghters situations.
Section 6 Accidental Release Measures
Personal Precautions No special precautions are necessary. Use good laboratory procedures.
Spill and Leak Absorb spilled material with an appropriate inert, non-flammable absorbent and
Procedures dispose according to local regulations.
Environmental Contain spill to prevent migration.
Precautions
Section 7 Handling and Storage
Handling Precautions No special precautions are necessary; use good laboratory procedures.
Recommended Storage To maintain efï¬cacy, store according to the instructions in the product labeling.
Conditions Keep away from incompatible material (see Section 10).
Section 8 Exposure Controls and Personal Protection
Exposure Limits
US OSHA: None established
ACGIH: None established
DFG MAK: None established
Engineering Controls No special engineering controls are required. Use with good general ventilation.
Respiratory Protection Under normal conditions, the use of this product should not require respiratory
protection.
Eye Protection Safety glasses or chemical goggles should be worn to prevent eye contact.
UltraTech AEC Doc. ID: IM2393-75 AA Page 9 of 11
Substrate Buffer
Section 8 Exposure Controls and Personal Protection (Continued)
Skin Protection Impervious gloves, such as Nitrile or equivalent, should be worn to prevent skin
contact.
Section 9 Physical and Chemical Properties
Physical State Liquid
Color Colorless
Transparency Clear
Odor Odorless
Odor Threshold Not applicable
pH Not available
Boiling Point Not available
Melting Point Not available
Speciï¬c Gravity 1 @20°C
Vapor Pressure Not available
Vapor Density Not available
Evaporation Rate Not available
Solubility
Water Miscible
Organic Not available
Section 10 Stability and Reactivity
Stability Stable under normal temperatures and pressures.
Hazardous Strong acids
Incompatibilities Strong bases
Strong oxidizers
Hazardous Decomposition products posing signiï¬cant hazards are not expected from the small
Decomposition Products volume of this product present during normal use.
Conditions to Avoid Avoid contact with incompatible materials.
Section 11 Toxicological Information
Toxicity Data Not applicable
for Hazardous Ingredients
Primary Routes The most likely routes of exposure are skin and eye contact.
of Exposure
Potential Effects of None identiï¬ed.
Acute Exposure
Potential Effects of None identiï¬ed.
Chronic Exposure
UltraTech AEC Doc. ID: IM2393-75 AA Page 10 of 11
Substrate Buffer
Section 11 Toxicological Information (Continued)
Symptoms of None identiï¬ed.
Overexposure
Carcinogenicity This product does not contain a reportable concentration (� 0.1%) of any ingredient
listed as carcinogen by ACGIH, IARC, NTP, OSHA or 67/548/EEC Annex I.
Other Effects None identiï¬ed.
Conditions Aggravated None identiï¬ed.
by Exposure
Section 12 Ecological Information
Ecotoxicity No information available.
Biodegradability No information available.
Mobility No information available.
Section 13 Disposal Considerations
Waste Disposal Dispose of waste product, unused product and contaminated packaging in compliance
with federal, state and local regulations. If unsure of the applicable requirements,
contact the authorities for information.
Section 14 Transport Information
Transportation of this product is not regulated under ICAO, IMDG, US DOT, European ADR or Canadian TDG.
Section 15 Regulatory Information
US Federal and State Regulations
SARA 313 No ingredients listed
CERCLA RG’s, No ingredients listed
40 CFR 302.4
California Proposition 65 No ingredients listed
Massachusetts MSL Hydrogen Peroxide is listed.
New Jersey Dept. of Hydrogen Peroxide is listed.
Health RTK List
Pennsylvania RTK Hydrogen Peroxide is listed.
EU Labeling Classiï¬cation
Preparation not classiï¬ed.
UltraTech AEC Doc. ID: IM2393-75 AA Page 11 of 11
Substrate Buffer
Section 15 Regulatory Information (Continued)
Canada
This product does not meet WHMIS criteria for hazardous materials.
PIN: Not applicable
Ingredients on Ingredient Hydrogen Peroxide
Disclosure List:
Ingredients with unknown None
toxicological properties:
Section 16 Other Information
For further information, please contact your local Beckman Coulter representative.
WHILE BECKMAN COULTER, INC. BELIEVES THE INFORMATION CONTAINED HEREIN IS VALID AND ACCURATE, BECKMAN COULTER MAKES NO WARRANTY OR
REPRESENTATION AS TO ITS VALIDITY, ACCURACY, OR CURRENCY. BECKMAN COULTER SHALL NOT BE LIABLE OR OTHERWISE RESPONSIBLE IN ANY WAY FOR USE
OF EITHER THIS INFORMATION OR MATERIALS TO WHICH IT APPLIES. DISPOSAL OF HAZARDOUS MATERIALS MAY BE SUBJECT TO LOCAL LAWS OR REGULATIONS.
Printed in U.S.A.
|