SIGMA-ALDRICH
Material Safety Data Sheet
Date Printed: 09/JUN/2005
Date Updated: 15/APR/2004
Version 1.3
According to 91/155/EEC
Classified as Hazardous according to the criteria of EU Annex 1 and
NOHSC.
1 - Product and Company Information
Product Name GAMMA-METHACRYLOXYPROPYL-
TRIMETHOXYSILANE
Product Number M6514
Company Sigma-Aldrich Pty. Ltd.
12 Anella Avenue
Castle Hill NSW 2154
Technical Phone # +61 2 9841 0555 (1800 800 097)
Fax +61 2 9841 0500 (1800 800 096)
Emergency Phone # +44 8701906777 (1800 448 465)
2 - Composition/Information on Ingredients
Product Name CAS # EC no Annex I
Index Number
3-(TRIMETHOXYSILYL)PROPYL 2530-85-0 219-785-8 607-134-00-4
METHACRYLATE
Formula C10H20O5Si
Molecular Weight 248.35 AMU
Synonyms Dynasylan MEMO * KBM 503 * KH 570 * M 8550 *
Methacrylic acid, 3-(trimethoxysilyl)propyl
ester * gamma-Methacryloxypropyltrimethoxysilane
* Mops-M * NUCA 174 * 2-Propenoic acid,
2-methyl-, 3-(trimethoxysilyl)propyl ester *
Silane, (3-hydroxypropyl)trimethoxy-,
methacrylat * Silicone A-174 *
3-(Trimethoxysilyl)-1-propanol methacrylate *
Trimethoxysilyl-3-propylester kyseliny
methakrylove (Czech) * Union carbide A-174
3 - Hazards Identification
SPECIAL INDICATION OF HAZARDS TO HUMANS AND THE ENVIRONMENT
Irritating to eyes, respiratory system and skin.
4 - First Aid Measures
AFTER INHALATION
If inhaled, remove to fresh air. If not breathing give
artificial respiration. If breathing is difficult, give oxygen.
AFTER SKIN CONTACT
In case of contact, immediately wash skin with soap and copious
amounts of water.
AFTER EYE CONTACT
In case of contact, immediately flush eyes with copious amounts
of water for at least 15 minutes.
AFTER INGESTION
If swallowed, wash out mouth with water provided person is
conscious. Call a physician.
5 - Fire Fighting Measures
CONDITIONS OF FLAMMABILITY
Under fire conditions, material may decompose to form flammable
and/or explosive mixtures in air.
EXTINGUISHING MEDIA
Suitable: Carbon dioxide, dry chemical powder, or appropriate
foam.
SPECIAL RISKS
Specific Hazard(s): Emits toxic fumes under fire conditions.
SPECIAL PROTECTIVE EQUIPMENT FOR FIREFIGHTERS
Wear self-contained breathing apparatus and protective clothing
to prevent contact with skin and eyes.
6 - Accidental Release Measures
PROCEDURE(S) OF PERSONAL PRECAUTION(S)
Wear respirator, chemical safety goggles, rubber boots, and
heavy rubber gloves.
METHODS FOR CLEANING UP
Absorb on sand or vermiculite and place in closed containers for
disposal. Ventilate area and wash spill site after material
pickup is complete.
7 - Handling and Storage
HANDLING
Directions for Safe Handling: Do not breathe vapor. Avoid
contact with eyes, skin, and clothing. Avoid prolonged or
repeated exposure.
STORAGE
Conditions of Storage: Keep tightly closed. Store in a cool dry
place. Handle and store under nitrogen.
Store at 2-8藲C
SPECIAL REQUIREMENTS: Moisture sensitive. Handle and store under
inert gas. Heat sensitive.
8 - Exposure Controls / Personal Protection
ENGINEERING CONTROLS
Mechanical exhaust required. Safety shower and eye bath.
GENERAL HYGIENE MEASURES
Wash thoroughly after handling.
PERSONAL PROTECTIVE EQUIPMENT
Respiratory Protection: Government approved respirator.
Hand Protection: Compatible chemical-resistant gloves.
Eye Protection: Chemical safety goggles.
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9 - Physical and Chemical Properties
Appearance Physical State: Liquid
Color: Colorless
Property Value At Temperature or Pressure
pH N/A
BP/BP Range 190 藲C 760 mmHg
MP/MP Range -48 藲C 760 mmHg
Flash Point 100 藲C Method: closed cup
Flammability N/A
Autoignition Temp 265 藲C
Oxidizing Properties N/A
Explosive Properties N/A
Explosion Limits Lower: 0.9 %
Upper: 5.4 %
Vapor Pressure 10 mmHg 130 藲C
SG/Density 1.045 g/cm3
Partition Coefficient N/A
Viscosity 0.003 Pas 25 藲C
Vapor Density 8.6 g/l
Saturated Vapor Conc. N/A
Evaporation Rate <1
Bulk Density N/A
Decomposition Temp. N/A
Solvent Content N/A
Water Content N/A
Surface Tension N/A
Conductivity N/A
Miscellaneous Data N/A
Solubility Solubility in Water:Soluble.
Other Solvents: SLOWLY REACTS W/WATER
10 - Stability and Reactivity
STABILITY
Stable: Stable.
Conditions of Instability: May decompose on exposure to moist air
or water.
Conditions to Avoid: Heat.
Materials to Avoid: Strong oxidizing agents, Strong acids, Strong
bases.
HAZARDOUS DECOMPOSITION PRODUCTS
Hazardous Decomposition Products: Carbon monoxide, Carbon dioxide,
Silicon oxide.
HAZARDOUS POLYMERIZATION
Hazardous Polymerization: May occur
11 - Toxicological Information
RTECS NUMBER: UC0230000
ACUTE TOXICITY
LD50
Oral
Rat
22600 UL/KG
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IRRITATION DATA
Skin
Rabbit
500 mg
24H
Remarks: Mild irritation effect
Eyes
Rabbit
500 mg
24H
Remarks: Mild irritation effect
SIGNS AND SYMPTOMS OF EXPOSURE
Contact with moisture liberates methanol. Ingestion of methanol
may cause blindness, nausea, headache, vomiting,
gastrointestinal upset, dizziness, irregular breathing,
weakness, confusion, drowsiness, unconsciousness, and death. To
the best of our knowledge, the chemical, physical, and
toxicological properties have not been thoroughly investigated.
ROUTE OF EXPOSURE
Skin Contact: Causes skin irritation.
Skin Absorption: May be harmful if absorbed through the skin.
Eye Contact: Causes eye irritation.
Inhalation: Material is irritating to mucous membranes and upper
respiratory tract. May be harmful if inhaled.
Ingestion: May be harmful if swallowed.
TARGET ORGAN INFORMATION
Eyes. Kidneys.
12 - Ecological Information
ELIMINATION
Elimination: 74 %
ECOTOXICOLOGICAL EFFECTS
Test Type: IC50 Algae
Species: Scenedesmus subspicatus
Time: 72 h
Value: > 536 mg/l
Test Type: EC50 Daphnia
Species: Daphnia magna
Time: 48 h
Value: > 876 mg/l
Test Type: LC50 Fish
Species: Brachydanio rerio
Time: 96 h
Value: > 1,042 mg/l
13 - Disposal Considerations
SUBSTANCE DISPOSAL
Contact a licensed professional waste disposal service to dispose
of this material. Dissolve or mix the material with a combustible
solvent and burn in a chemical incinerator equipped with an
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afterburner and scrubber. Observe all federal, state, and local
environmental regulations.
14 - Transport Information
RID/ADR
Non-hazardous for road transport.
IMDG
Non-hazardous for sea transport.
IATA
Non-hazardous for air transport.
15 - Regulatory Information
CLASSIFICATION AND LABELING ACCORDING TO EU DIRECTIVES
ANNEX I INDEX NUMBER: 607-134-00-4
INDICATION OF DANGER: Xi
Irritant.
R-PHRASES: 36/37/38
Irritating to eyes, respiratory system and skin.
S-PHRASES: 26 28
In case of contact with eyes, rinse immediately with plenty of
water and seek medical advice. After contact with skin, wash
immediately with plenty of soap-suds.
COUNTRY SPECIFIC INFORMATION
Germany
WGK: 1 (self-classification)
SWITZERLAND
SWISS POISON CLASS: 5
16 - Other Information
WARRANTY
The above information is believed to be correct but does not
purport to be all inclusive and shall be used only as a guide. The
information in this document is based on the present state of our
knowledge and is applicable to the product with regard to
appropriate safety precautions. It does not represent any
guarantee of the properties of the product. Sigma-Aldrich Inc.,
shall not be held liable for any damage resulting from handling or
from contact with the above product. See reverse side of invoice
or packing slip for additional terms and conditions of sale.
Copyright 2005 Sigma-Aldrich Co. License granted to make unlimited
paper copies for internal use only.
DISCLAIMER
For R&D use only. Not for drug, household or other uses.
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