SIGMA-ALDRICH
Material Safety Data Sheet
Date Printed: 12/APR/2005
Date Updated: 18/JUN/2004
Version 1.3
According to 91/155/EEC
Classified as Hazardous according to the criteria of EU Annex 1 and
NOHSC.
1 - Product and Company Information
Product Name METHYL VINYL KETONE, 99%
Product Number 269549
Company Sigma-Aldrich Pty, Ltd
Unit 2, 14 Anella Avenue
Castle Hill NSW 1765
Australia
Technical Phone # +61 2 9841 0555
Fax +61 2 9841 0500
Emergency Phone # +61 2 9841 0566
2 - Composition/Information on Ingredients
Product Name CAS # EC no Annex I
Index Number
3-BUTEN-2-ONE 78-94-4 201-160-6 None
Formula C4H6O
Molecular Weight 70.09 AMU
Synonyms Acetone, methylene- * Acetyl ethylene *
3-Butene-2-one * Butenone * delta(sup
3)-2-Butenone * Ketone, methyl vinyl * Methylene
acetone * Methyl-vinyl-cetone (French) *
Methylvinylketon (German) * Methylvinyl ketone *
gamma-Oxo-alpha-butylene * Vinyl methyl ketone
3 - Hazards Identification
SPECIAL INDICATION OF HAZARDS TO HUMANS AND THE ENVIRONMENT
Highly flammable. Very toxic by inhalation and if swallowed.
Causes burns.
4 - First Aid Measures
AFTER INHALATION
If inhaled, remove to fresh air. If not breathing give
artificial respiration. If breathing is difficult, give oxygen.
AFTER SKIN CONTACT
In case of skin contact, flush with copious amounts of water for
at least 15 minutes. Remove contaminated clothing and shoes.
Call a physician.
AFTER EYE CONTACT
In case of contact with eyes, flush with copious amounts of
water for at least 15 minutes. Assure adequate flushing by
separating the eyelids with fingers. Call a physician.
AFTER INGESTION
If swallowed, wash out mouth with water provided person is
conscious. Call a physician immediately.
5 - Fire Fighting Measures
EXTINGUISHING MEDIA
Suitable: Water spray. Carbon dioxide, dry chemical powder, or
appropriate foam.
SPECIAL RISKS
Specific Hazard(s): Flammable liquid. Emits toxic fumes under
fire conditions.
Explosion Hazards: Vapor may travel considerable distance to
source of ignition and flash back. Container explosion may occur
under fire conditions.
SPECIAL PROTECTIVE EQUIPMENT FOR FIREFIGHTERS
Wear self-contained breathing apparatus and protective clothing
to prevent contact with skin and eyes.
6 - Accidental Release Measures
PERSONAL PRECAUTION PROCEDURES TO BE FOLLOWED IN CASE OF LEAK OR SPILL
Evacuate area. Shut off all sources of ignition.
PROCEDURE(S) OF PERSONAL PRECAUTION(S)
Wear self-contained breathing apparatus, rubber boots, and heavy
rubber gloves.
METHODS FOR CLEANING UP
Cover with dry-lime, sand, or soda ash. Place in covered
containers using non-sparking tools and transport outdoors.
Ventilate area and wash spill site after material pickup is
complete.
7 - Handling and Storage
HANDLING
Directions for Safe Handling: Do not breathe vapor. Do not get
in eyes, on skin, on clothing. Avoid prolonged or repeated
exposure.
STORAGE
Conditions of Storage: Keep tightly closed. Keep away from heat,
sparks, and open flame.
Store at 2-8掳C
SPECIAL REQUIREMENTS: Heat and light sensitive.
8 - Exposure Controls / Personal Protection
ENGINEERING CONTROLS
Safety shower and eye bath. Use nonsparking tools. Use only in a
chemical fume hood.
GENERAL HYGIENE MEASURES
Wash contaminated clothing before reuse. Wash thoroughly after
handling.
PERSONAL PROTECTIVE EQUIPMENT
ALDRICH - 269549 www.sigma-aldrich.com Page 2
Respiratory Protection: Government approved respirator.
Hand Protection: Compatible chemical-resistant gloves.
Eye Protection: Chemical safety goggles.
9 - Physical and Chemical Properties
Appearance Physical State: Clear liquid
Color: Faintly yellow
Property Value At Temperature or Pressure
pH N/A
BP/BP Range 36.5 - 36.80 掳C 145 mmHg
MP/MP Range -7 掳C
Flash Point -7 掳C Method: closed cup
Flammability N/A
Autoignition Temp 491 掳C
Oxidizing Properties N/A
Explosive Properties N/A
Explosion Limits Lower: 2.14 %
Upper: 15.64 %
Vapor Pressure 71 mmHg 20 掳C
SG/Density 0.855 g/cm3
Partition Coefficient Log Kow: 0.117
Viscosity N/A
Vapor Density 1.3 g/l
Saturated Vapor Conc. N/A
Evaporation Rate N/A
Bulk Density N/A
Decomposition Temp. N/A
Solvent Content N/A
Water Content <5%
Surface Tension 24 mN/m 20 掳C
Conductivity N/A
Miscellaneous Data N/A
Solubility Solubility in Water:Soluble.
Other Solvents: METHANOL, GLACIAL ACETIC
ACID BENZENE, ACETONE, ETHE
10 - Stability and Reactivity
STABILITY
Conditions of Instability: Heat sensitive. Light sensitive.
Materials to Avoid: Strong bases, Strong oxidizing agents, Strong
reducing agents.
HAZARDOUS DECOMPOSITION PRODUCTS
Hazardous Decomposition Products: Carbon monoxide, Carbon dioxide.
HAZARDOUS POLYMERIZATION
Hazardous Polymerization: Will not occur
11 - Toxicological Information
RTECS NUMBER: EM9800000
ACUTE TOXICITY
LD50
Oral
Rat
23.1 mg/kg
ALDRICH - 269549 www.sigma-aldrich.com Page 3
LC50
Inhalation
Rat
7 mg/m3
4H
LD50
Oral
Mouse
23.3 mg/kg
LC50
Inhalation
Mouse
8 mg/m3
2H
LD50
Intraperitoneal
Mouse
76 MG/KG
IRRITATION DATA
Eyes
Remarks: Severe irritation effect
Skin
Remarks: Severe irritation effect
Inhalation
Remarks: Severe irritation effect
SIGNS AND SYMPTOMS OF EXPOSURE
Material is extremely destructive to tissue of the mucous
membranes and upper respiratory tract, eyes, and skin.
Inhalation may result in spasm, inflammation and edema of the
larynxand bronchi, chemical pneumonitis, and pulmonary edema.
Symptoms of exposure may include burning sensation, coughing,
wheezing, laryngitis, shortness of breath, headache, nausea, and
vomiting. To the best of our knowledge, the chemical, physical,
and toxicological properties have not been thoroughly
investigated.
ROUTE OF EXPOSURE
Skin Contact: Causes burns. Vesicant. Causes blisters on contact
with skin.
Skin Absorption: May be harmful if absorbed through the skin.
Readily absorbed through skin.
Eye Contact: Causes burns. Lachrymator.
Inhalation: May be fatal if inhaled. Material is extremely
destructive to the tissue of the mucous membranes and upper
respiratory tract.
Ingestion: May be fatal if swallowed.
CHRONIC EXPOSURE - MUTAGEN
Mutation test: Histidine reversion (Ames)
12 - Ecological Information
ELIMINATION
Elimination: 0 %
ALDRICH - 269549 www.sigma-aldrich.com Page 4
ECOTOXICOLOGICAL EFFECTS
Test Type: EC50 Algae
Species: Selenastrum capricornutum resp.
Time: 96 h
Value: 0.12 - 0.130 mg/l
13 - Disposal Considerations
SUBSTANCE DISPOSAL
Contact a licensed professional waste disposal service to dispose
of this material. Burn in a chemical incinerator equipped with an
afterburner and scrubber but exert extra care in igniting as this
material is highly flammable. Observe all federal, state, and
local environmental regulations.
14 - Transport Information
RID/ADR
UN#: 1251
Class: 6.1
PG: I
Proper Shipping Name: Methyl vinyl ketone, stabilized
IMDG
UN#: 1251
Class: 6.1
PG: I
Subrisk: 3/8
Proper Shipping Name: METHYL VINYL KETONE
Marine Pollutant: No
Severe Marine Pollutant: No
IATA
UN#: 1251
Class: 6.1
PG: II
Subrisk: 38
Proper Shipping Name: Methyl vinyl ketone, stabilized
Inhalation Packing Group I: Yes
15 - Regulatory Information
CLASSIFICATION AND LABELING ACCORDING TO EU DIRECTIVES
INDICATION OF DANGER: F T+
Highly Flammable. Very toxic.
R-PHRASES: 11 26/28 34
Highly flammable. Very toxic by inhalation and if swallowed.
Causes burns.
S-PHRASES: 16 26 28 36/37/39 45
Keep away from sources of ignition - no smoking. In case of
contact with eyes, rinse immediately with plenty of water and
seek medical advice. After contact with skin, wash immediately
with plenty of water. Wear suitable protective clothing,
gloves, and eye/face protection. In case of accident or if you
feel unwell, seek medical advice immediately (show the label
where possible).
COUNTRY SPECIFIC INFORMATION
Germany
WGK: 3
ALDRICH - 269549 www.sigma-aldrich.com Page 5
16 - Other Information
WARRANTY
The above information is believed to be correct but does not
purport to be all inclusive and shall be used only as a guide. The
information in this document is based on the present state of our
knowledge and is applicable to the product with regard to
appropriate safety precautions. It does not represent any
guarantee of the properties of the product. Sigma-Aldrich Inc.,
shall not be held liable for any damage resulting from handling or
from contact with the above product. See reverse side of invoice
or packing slip for additional terms and conditions of sale.
Copyright 2005 Sigma-Aldrich Co. License granted to make unlimited
paper copies for internal use only.
DISCLAIMER
For R&D use only. Not for drug, household or other uses.
ALDRICH - 269549 www.sigma-aldrich.com Page 6
|