SIGMA-ALDRICH
Material Safety Data Sheet
Date Printed: 07/JUN/2005
Date Updated: 13/MAR/2004
Version 1.3
According to 91/155/EEC
Classified as Hazardous according to the criteria of EU Annex 1 and
NOHSC.
1 - Product and Company Information
Product Name INDIGO CARMINE
Product Number I8130
Company Sigma-Aldrich Pty. Ltd.
12 Anella Avenue
Castle Hill NSW 2154
Australia
Technical Phone # +61 2 9841 0555 (1800 800 097)
Fax +61 2 9841 0500 (1800 800 096)
Emergency Phone # +44 8701906777 (1800 448 465)
2 - Composition/Information on Ingredients
Product Name CAS # EC no Annex I
Index Number
INDIGO CARMINE 860-22-0 212-728-8 None
Formula C16H8N2Na2O8S2
Molecular Weight 466.36 AMU
Synonyms Acid Blue W * Acid Leather Blue IC * A.F. Blue
No. 2 * Airedale Blue IN * Amacid Brilliant Blue
* Aniline Carmine powder * Atul Indigo Carmine *
1311 Blue * 12070 Blue * Bucacid indigotine B *
Canacert Indigo Carmine * Carmine Blue
(biological stain) * C.I. 73015 * C.I. 75781 *
C.I. Acid Blue 74 * C.I. Food Blue 1 * C.I. Food
Blue 1, disodium salt * Cilefa Blue R * C.I.
Natural Blue 2 * Disodium indigo-5,5-disulfonate
* Disodium salt of 1-indigotin-S,S'-disulphonic
aci * Dolkwal Indigo Carmine * E 132 * Edicol
Supra Blue X * FD and C Blue No. 2 * Food Blue 2
* Grape Blue A Geigy * HD Indigo Carmine * HD
Indigo Carmine Supra * Hexacert Blue No. 2 *
Hexacol Indigo Carmine Supra * Indigo Carmine *
Indigo Carmine A * Indigo Carmine AC * Indigo
Carmine (biological stain) * Indigo Carmine BP *
Indigo Carmine Conc. FQ * Indigo Carmine
disodium salt * Indigo Carmine powder * Indigo
Carmine X * Indigo disulfonate (biological
stain) * Indigo extract * Indigo-karmin (German)
* Indigotin I * 5,5'-Indigotindisulfonic acid *
Indigotin-5,5'-disulfonic acid disodium salt *
3 - Hazards Identification
SPECIAL INDICATION OF HAZARDS TO HUMANS AND THE ENVIRONMENT
Harmful if swallowed.
4 - First Aid Measures
AFTER INHALATION
If inhaled, remove to fresh air. If not breathing give
artificial respiration. If breathing is difficult, give oxygen.
AFTER SKIN CONTACT
In case of skin contact, flush with copious amounts of water for
at least 15 minutes. Remove contaminated clothing and shoes.
Call a physician.
AFTER EYE CONTACT
In case of contact with eyes, flush with copious amounts of
water for at least 15 minutes. Assure adequate flushing by
separating the eyelids with fingers. Call a physician.
AFTER INGESTION
If swallowed, wash out mouth with water provided person is
conscious. Call a physician.
5 - Fire Fighting Measures
EXTINGUISHING MEDIA
Suitable: Water spray. Carbon dioxide, dry chemical powder, or
appropriate foam.
SPECIAL RISKS
Specific Hazard(s): Emits toxic fumes under fire conditions.
SPECIAL PROTECTIVE EQUIPMENT FOR FIREFIGHTERS
Wear self-contained breathing apparatus and protective clothing
to prevent contact with skin and eyes.
6 - Accidental Release Measures
PERSONAL PRECAUTION PROCEDURES TO BE FOLLOWED IN CASE OF LEAK OR SPILL
Evacuate area.
PROCEDURE(S) OF PERSONAL PRECAUTION(S)
Wear self-contained breathing apparatus, rubber boots, and heavy
rubber gloves.
METHODS FOR CLEANING UP
Sweep up, place in a bag and hold for waste disposal. Avoid
raising dust. Ventilate area and wash spill site after material
pickup is complete.
7 - Handling and Storage
HANDLING
Directions for Safe Handling: Do not breathe dust. Avoid contact
with eyes, skin, and clothing. Avoid prolonged or repeated
exposure.
STORAGE
Conditions of Storage: Keep tightly closed.
SPECIAL REQUIREMENTS: Light sensitive.
8 - Exposure Controls / Personal Protection
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ENGINEERING CONTROLS
Safety shower and eye bath. Mechanical exhaust required.
GENERAL HYGIENE MEASURES
Wash thoroughly after handling.
PERSONAL PROTECTIVE EQUIPMENT
Respiratory Protection: Government approved respirator.
Hand Protection: Compatible chemical-resistant gloves.
Eye Protection: Chemical safety goggles.
9 - Physical and Chemical Properties
Appearance Physical State: Solid
Color: Deep violet
Form: Powder
Property Value At Temperature or Pressure
pH N/A
BP/BP Range N/A
MP/MP Range N/A
Flash Point N/A
Flammability N/A
Autoignition Temp N/A
Oxidizing Properties N/A
Explosive Properties N/A
Explosion Limits N/A
Vapor Pressure N/A
SG/Density N/A
Partition Coefficient N/A
Viscosity N/A
Vapor Density N/A
Saturated Vapor Conc. N/A
Evaporation Rate N/A
Bulk Density N/A
Decomposition Temp. N/A
Solvent Content N/A
Water Content N/A
Surface Tension N/A
Conductivity N/A
Miscellaneous Data N/A
Solubility N/A
10 - Stability and Reactivity
STABILITY
Stable: Stable.
Materials to Avoid: Strong oxidizing agents.
HAZARDOUS DECOMPOSITION PRODUCTS
Hazardous Decomposition Products: Carbon monoxide, Carbon dioxide,
Nitrogen oxides, Sulfur oxides.
HAZARDOUS POLYMERIZATION
Hazardous Polymerization: Will not occur
11 - Toxicological Information
RTECS NUMBER: DU3000000
ACUTE TOXICITY
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LD50
Oral
Rat
2000 mg/kg
LD50
Intravenous
Rat
93 MG/KG
LD50
Oral
Mouse
2500 mg/kg
LD50
Subcutaneous
Mouse
405 MG/KG
SIGNS AND SYMPTOMS OF EXPOSURE
To the best of our knowledge, the chemical, physical, and
toxicological properties have not been thoroughly investigated.
ROUTE OF EXPOSURE
Skin Contact: May cause skin irritation.
Skin Absorption: May be harmful if absorbed through the skin.
Eye Contact: May cause eye irritation.
Inhalation: May be harmful if inhaled.
Ingestion: Harmful if swallowed.
CHRONIC EXPOSURE - CARCINOGEN
Rat
Route of Application: Subcutaneous
Exposure Time: 2Y
Result: Tumorigenic:Neoplastic by RTECS criteria.
Tumorigenic:Tumors at site or application.
CHRONIC EXPOSURE - MUTAGEN
Mouse
5400 MG/KG
Oral
90D
Cytogenetic analysis
Mouse
60 MG/KG
Oral
30D
Cytogenetic analysis
Mouse
25 MG/KG
Intraperitoneal
Sister chromatid exchange
Hamster
12 GM/L
Cell Type: fibroblast
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Cytogenetic analysis
Hamster
20 UMOL/L
5H
Cell Type: ovary
Cytogenetic analysis
ZNEG
Histidine reversion (Ames)
12 - Ecological Information
No data available.
13 - Disposal Considerations
SUBSTANCE DISPOSAL
Contact a licensed professional waste disposal service to dispose
of this material. Dissolve or mix the material with a combustible
solvent and burn in a chemical incinerator equipped with an
afterburner and scrubber. Observe all federal, state, and local
environmental regulations.
14 - Transport Information
RID/ADR
Non-hazardous for road transport.
IMDG
Non-hazardous for sea transport.
IATA
Non-hazardous for air transport.
15 - Regulatory Information
CLASSIFICATION AND LABELING ACCORDING TO EU DIRECTIVES
INDICATION OF DANGER: Xn
Harmful.
R-PHRASES: 22
Harmful if swallowed.
S-PHRASES: 22 24/25
Do not breathe dust. Avoid contact with skin and eyes.
16 - Other Information
WARRANTY
The above information is believed to be correct but does not
purport to be all inclusive and shall be used only as a guide. The
information in this document is based on the present state of our
knowledge and is applicable to the product with regard to
appropriate safety precautions. It does not represent any
guarantee of the properties of the product. Sigma-Aldrich Inc.,
shall not be held liable for any damage resulting from handling or
from contact with the above product. See reverse side of invoice
or packing slip for additional terms and conditions of sale.
Copyright 2005 Sigma-Aldrich Co. License granted to make unlimited
paper copies for internal use only.
DISCLAIMER
For R&D use only. Not for drug, household or other uses.
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