SIGMA-ALDRICH



                         Material Safety Data Sheet



                                               Date Printed: 09/AUG/2005

                                               Date Updated: 17/MAY/2005

                                                             Version 1.4

                                                 According to 91/155/EEC





1 - Product and Company Information



Product Name                   HEXADIMETHRINE BROMIDE, >=95%

Product Number                 107689



Company                        Sigma-Aldrich Pty. Ltd.

                               12 Anella Avenue

                               Castle Hill NSW 2154

Technical Phone #              +61 2 9841 0555 (1800 800 097)

Fax                            +61 2 9841 0500 (1800 800 096)

Emergency Phone #              +44 8701906777 (1800 448 465)



2 - Composition/Information on Ingredients



Product Name                         CAS #        EC no     Annex I

                                                            Index Number

HEXADIMETHRINE BROMIDE               28728-55-4   None      None



Synonyms            6,3-Ionene bromide * Polybrene * Polybrene



3 - Hazards Identification





SPECIAL INDICATION OF HAZARDS TO HUMANS AND THE ENVIRONMENT

   Not hazardous according to Directive 67/548/EEC.



4 - First Aid Measures



AFTER INHALATION

   If inhaled, remove to fresh air. If breathing becomes difficult,

   call a physician.



AFTER SKIN CONTACT

   In case of contact, immediately wash skin with soap and copious

   amounts of water.



AFTER EYE CONTACT

   In case of contact with eyes, flush with copious amounts of

   water for at least 15 minutes. Assure adequate flushing by

   separating the eyelids with fingers. Call a physician.



AFTER INGESTION

   If swallowed, wash out mouth with water provided person is

   conscious. Call a physician.



5 - Fire Fighting Measures



EXTINGUISHING MEDIA

   Suitable: Water spray. Carbon dioxide, dry chemical powder, or

   appropriate foam.



SPECIAL RISKS

   Specific Hazard(s): Emits toxic fumes under fire conditions.



SPECIAL PROTECTIVE EQUIPMENT FOR FIREFIGHTERS

   Wear self-contained breathing apparatus and protective clothing

   to prevent contact with skin and eyes.



6 - Accidental Release Measures



PROCEDURE(S) OF PERSONAL PRECAUTION(S)

   Exercise appropriate precautions to minimize direct contact with

   skin or eyes and prevent inhalation of dust.



METHODS FOR CLEANING UP

   Sweep up, place in a bag and hold for waste disposal. Avoid

   raising dust. Ventilate area and wash spill site after material

   pickup is complete.



7 - Handling and Storage



HANDLING

   Directions for Safe Handling: Avoid inhalation. Avoid contact

   with eyes, skin, and clothing. Avoid prolonged or repeated

   exposure.



STORAGE

   Conditions of Storage: Keep tightly closed.

   Incompatible Materials: Moisture.



SPECIAL REQUIREMENTS: Hygroscopic.



8 - Exposure Controls / Personal Protection



ENGINEERING CONTROLS

   Safety shower and eye bath. Mechanical exhaust required.



GENERAL HYGIENE MEASURES

   Wash thoroughly after handling.



PERSONAL PROTECTIVE EQUIPMENT

   Respiratory Protection: Wear dust mask.

   Hand Protection: Protective gloves.

   Eye Protection: Chemical safety goggles.



9 - Physical and Chemical Properties



Appearance              Physical State: Solid



Property                Value                 At Temperature or Pressure



pH                      N/A

BP/BP Range             N/A

MP/MP Range             N/A

Flash Point             N/A

Flammability            N/A

Autoignition Temp       N/A

Oxidizing Properties    N/A

Explosive Properties    N/A

Explosion Limits        N/A

Vapor Pressure          N/A

SG/Density              N/A

Partition Coefficient   N/A

Viscosity               N/A





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Vapor Density             N/A

Saturated Vapor Conc.     N/A

Evaporation Rate          N/A

Bulk Density              N/A

Decomposition Temp.       N/A

Solvent Content           N/A

Water Content             N/A

Surface Tension           N/A

Conductivity              N/A

Miscellaneous Data        N/A

Solubility                Solubility in Water:0.1 g/ml H2O



10 - Stability and Reactivity



STABILITY

   Stable: Stable.

   Conditions of Instability: Moisture sensitive.



HAZARDOUS DECOMPOSITION PRODUCTS

   Hazardous Decomposition Products: Carbon monoxide, Carbon dioxide,

   Nitrogen oxides, Hydrogen bromide gas.



HAZARDOUS POLYMERIZATION

   Hazardous Polymerization: Will not occur



11 - Toxicological Information



RTECS NUMBER: TQ2655000



ACUTE TOXICITY



   LD50

   Intravenous

   Rat

   20 MG/KG



   LD50

   Oral

   Mouse

   > 1000 mg/kg



   LD50

   Intraperitoneal

   Mouse

   30 MG/KG



   LD50

   Intravenous

   Mouse

   28 MG/KG



SIGNS AND SYMPTOMS OF EXPOSURE

   To the best of our knowledge, the chemical, physical, and

   toxicological properties have not been thoroughly investigated.



ROUTE OF EXPOSURE

   Skin Contact: May cause skin irritation.

   Skin Absorption: May be harmful if absorbed through the skin.

   Eye Contact: May cause eye irritation.

   Inhalation: May be harmful if inhaled. Material may be

   irritating to mucous membranes and upper respiratory tract.

   Ingestion: May be harmful if swallowed.





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TARGET ORGAN INFORMATION

   Blood. Kidneys.



12 - Ecological Information



No data available.



13 - Disposal Considerations



SUBSTANCE DISPOSAL

   Contact a licensed professional waste disposal service to dispose

   of this material. Dissolve or mix the material with a combustible

   solvent and burn in a chemical incinerator equipped with an

   afterburner and scrubber. Observe all federal, state, and local

   environmental regulations.



14 - Transport Information



RID/ADR

   Non-hazardous for road transport.



IMDG

   Non-hazardous for sea transport.



IATA

   Non-hazardous for air transport.



15 - Regulatory Information



Not hazardous according to Directive 67/548/EEC.



COUNTRY SPECIFIC INFORMATION



Germany

   WGK: 3 (Self classification)



16 - Other Information



WARRANTY

   The above information is believed to be correct but does not

   purport to be all inclusive and shall be used only as a guide. The

   information in this document is based on the present state of our

   knowledge and is applicable to the product with regard to

   appropriate safety precautions. It does not represent any

   guarantee of the properties of the product. Sigma-Aldrich Inc.,

   shall not be held liable for any damage resulting from handling or

   from contact with the above product. See reverse side of invoice

   or packing slip for additional terms and conditions of sale.

   Copyright 2005 Sigma-Aldrich Co. License granted to make unlimited

   paper copies for internal use only.



DISCLAIMER

   For R&D use only. Not for drug, household or other uses.









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