ACETONE
MSDS Number: A0446 * * * * * Effective Date: 02/01/07 * * * * * Supercedes: 05/20/04
ACETONE
1. Product Identification
Synonyms: Dimethylketone; 2-propanone; dimethylketal
CAS No.: 67-64-1
Molecular Weight: 58.08
Chemical Formula: (CH3)2CO
Product Codes:
J.T. Baker: 5008, 5018, 5356, 5580, 5965, 5975, 9001, 9002, 9003, 9004, 9005, 9006, 9007, 9008, 9009, 9010, 9015,
9024, 9036, 9125, 9254, 9271, A134, V655
Mallinckrodt: 0018, 2432, 2435, 2437, 2438, 2440, 2443, 2850, H451, H580, H981
2. Composition/Information on Ingredients
Ingredient CAS No Percent
Hazardous
--------------------------------------- ------------ ------------ ---------
Acetone 67-64-1 99 - 100%
Yes
3. Hazards Identification
Emergency Overview
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--------------------------
DANGER! EXTREMELY FLAMMABLE LIQUID AND VAPOR. VAPOR MAY CAUSE FLASH FIRE.
HARMFUL IF SWALLOWED OR INHALED. CAUSES IRRITATION TO SKIN, EYES AND
RESPIRATORY TRACT. AFFECTS CENTRAL NERVOUS SYSTEM.
SAF-T-DATA(tm) Ratings (Provided here for your convenience)
-----------------------------------------------------------------------------------------------------------
Health Rating: 2 - Moderate
Flammability Rating: 3 - Severe (Flammable)
Reactivity Rating: 0 - None
Contact Rating: 3 - Severe
Lab Protective Equip: GOGGLES & SHIELD; LAB COAT & APRON; VENT HOOD; PROPER GLOVES; CLASS
B EXTINGUISHER
Storage Color Code: Red (Flammable)
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Potential Health Effects
----------------------------------
Inhalation:
Inhalation of vapors irritates the respiratory tract. May cause coughing, dizziness, dullness, and headache. Higher
concentrations can produce central nervous system depression, narcosis, and unconsciousness.
Ingestion:
Swallowing small amounts is not likely to produce harmful effects. Ingestion of larger amounts may produce
abdominal pain, nausea and vomiting. Aspiration into lungs can produce severe lung damage and is a medical
emergency. Other symptoms are expected to parallel inhalation.
Skin Contact:
Irritating due to defatting action on skin. Causes redness, pain, drying and cracking of the skin.
Eye Contact:
Vapors are irritating to the eyes. Splashes may cause severe irritation, with stinging, tearing, redness and pain.
Chronic Exposure:
Prolonged or repeated skin contact may produce severe irritation or dermatitis.
Aggravation of Pre-existing Conditions:
Use of alcoholic beverages enhances toxic effects. Exposure may increase the toxic potential of chlorinated
hydrocarbons, such as chloroform, trichloroethane.
4. First Aid Measures
Inhalation:
Remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical
attention.
Ingestion:
Aspiration hazard. If swallowed, vomiting may occur spontaneously, but DO NOT INDUCE. If vomiting occurs, keep
head below hips to prevent aspiration into lungs. Never give anything by mouth to an unconscious person. Call a
physician immediately.
Skin Contact:
Immediately flush skin with plenty of water for at least 15 minutes. Remove contaminated clothing and shoes. Get
medical attention. Wash clothing before reuse. Thoroughly clean shoes before reuse.
Eye Contact:
Immediately flush eyes with plenty of water for at least 15 minutes, lifting upper and lower eyelids occasionally. Get
medical attention.
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5. Fire Fighting Measures
Fire:
Flash point: -20C (-4F) CC
Autoignition temperature: 465C (869F)
Flammable limits in air % by volume:
lel: 2.5; uel: 12.8
Extremely Flammable Liquid and Vapor! Vapor may cause flash fire.
Explosion:
Above flash point, vapor-air mixtures are explosive within flammable limits noted above. Vapors can flow along
surfaces to distant ignition source and flash back. Contact with strong oxidizers may cause fire. Sealed containers may
rupture when heated. This material may produce a floating fire hazard. Sensitive to static discharge.
Fire Extinguishing Media:
Dry chemical, alcohol foam or carbon dioxide. Water may be ineffective. Water spray may be used to keep fire
exposed containers cool, dilute spills to nonflammable mixtures, protect personnel attempting to stop leak and disperse
vapors.
Special Information:
In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full
facepiece operated in the pressure demand or other positive pressure mode.
6. Accidental Release Measures
Ventilate area of leak or spill. Remove all sources of ignition. Wear appropriate personal protective equipment as
specified in Section 8. Isolate hazard area. Keep unnecessary and unprotected personnel from entering. Contain and
recover liquid when possible. Use non-sparking tools and equipment. Collect liquid in an appropriate container or
absorb with an inert material (e. g., vermiculite, dry sand, earth), and place in a chemical waste container. Do not use
combustible materials, such as saw dust. Do not flush to sewer! If a leak or spill has not ignited, use water spray to
disperse the vapors, to protect personnel attempting to stop leak, and to flush spills away from exposures. US
Regulations (CERCLA) require reporting spills and releases to soil, water and air in excess of reportable quantities.
The toll free number for the US Coast Guard National Response Center is (800) 424-8802.
J. T. Baker SOLUSORB庐 solvent adsorbent is recommended for spills of this product.
7. Handling and Storage
Protect against physical damage. Store in a cool, dry well-ventilated location, away from any area where the fire
hazard may be acute. Outside or detached storage is preferred. Separate from incompatibles. Containers should be
bonded and grounded for transfers to avoid static sparks. Storage and use areas should be No Smoking areas. Use non-
sparking type tools and equipment, including explosion proof ventilation. Containers of this material may be hazardous
when empty since they retain product residues (vapors, liquid); observe all warnings and precautions listed for the
product.
8. Exposure Controls/Personal Protection
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Airborne Exposure Limits:
Acetone:
-OSHA Permissible Exposure Limit (PEL):
1000 ppm (TWA)
-ACGIH Threshold Limit Value (TLV):
500 ppm (TWA), 750 ppm (STEL) A4 - not classifiable as a human carcinogen
Ventilation System:
A system of local and/or general exhaust is recommended to keep employee exposures below the Airborne Exposure
Limits. Local exhaust ventilation is generally preferred because it can control the emissions of the contaminant at its
source, preventing dispersion of it into the general work area. Please refer to the ACGIH document, Industrial
Ventilation, A Manual of Recommended Practices, most recent edition, for details.
Personal Respirators (NIOSH Approved):
If the exposure limit is exceeded and engineering controls are not feasible, a half-face organic vapor respirator may be
worn for up to ten times the exposure limit, or the maximum use concentration specified by the appropriate regulatory
agency or respirator supplier, whichever is lowest. A full-face piece organic vapor respirator may be worn up to 50
times the exposure limit, or the maximum use concentration specified by the appropriate regulatory agency or
respirator supplier, whichever is lowest. For emergencies or instances where the exposure levels are not known, use a
full-face piece positive-pressure, air-supplied respirator. WARNING: Air-purifying respirators do not protect workers
in oxygen-deficient atmospheres.
Skin Protection:
Wear impervious protective clothing, including boots, gloves, lab coat, apron or coveralls, as appropriate, to prevent
skin contact.
Eye Protection:
Use chemical safety goggles and/or a full face shield where splashing is possible. Maintain eye wash fountain and
quick-drench facilities in work area.
9. Physical and Chemical Properties
Appearance:
Clear, colorless, volatile liquid.
Odor:
Fragrant, mint-like
Solubility:
Miscible in all proportions in water.
Specific Gravity:
0.79 @ 20C/4C
pH:
No information found.
% Volatiles by volume @ 21C (70F):
100
Boiling Point:
56.5C (133F) @ 760 mm Hg
Melting Point:
-95C (-139F)
Vapor Density (Air=1):
2.0
Vapor Pressure (mm Hg):
400 @ 39.5C (104F)
Evaporation Rate (BuAc=1):
ca. 7.7
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10. Stability and Reactivity
Stability:
Stable under ordinary conditions of use and storage.
Hazardous Decomposition Products:
Carbon dioxide and carbon monoxide may form when heated to decomposition.
Hazardous Polymerization:
Will not occur.
Incompatibilities:
Concentrated nitric and sulfuric acid mixtures, oxidizing materials, chloroform, alkalis, chlorine compounds, acids,
potassium t-butoxide.
Conditions to Avoid:
Heat, flames, ignition sources and incompatibles.
11. Toxicological Information
Oral rat LD50: 5800 mg/kg; Inhalation rat LC50: 50,100mg/m3; Irritation eye rabbit, Standard Draize, 20 mg severe;
investigated as a tumorigen, mutagen, reproductive effector.
--------\Cancer Lists\------------------------------------------------------
---NTP Carcinogen---
Ingredient Known Anticipated IARC Category
------------------------------------ ----- ----------- -------------
Acetone (67-64-1) No No None
12. Ecological Information
Environmental Fate:
When released into the soil, this material is expected to readily biodegrade. When released into the soil, this material is
expected to leach into groundwater. When released into the soil, this material is expected to quickly evaporate. When
released into water, this material is expected to readily biodegrade. When released to water, this material is expected to
quickly evaporate. This material has a log octanol-water partition coefficient of less than 3.0. This material is not
expected to significantly bioaccumulate. When released into the air, this material may be moderately degraded by
reaction with photochemically produced hydroxyl radicals. When released into the air, this material may be moderately
degraded by photolysis. When released into the air, this material is expected to be readily removed from the
atmosphere by wet deposition.
Environmental Toxicity:
This material is not expected to be toxic to aquatic life. The LC50/96-hour values for fish are over 100 mg/l.
13. Disposal Considerations
Whatever cannot be saved for recovery or recycling should be handled as hazardous waste and sent to a RCRA
approved incinerator or disposed in a RCRA approved waste facility. Processing, use or contamination of this product
may change the waste management options. State and local disposal regulations may differ from federal disposal
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regulations. Dispose of container and unused contents in accordance with federal, state and local requirements.
14. Transport Information
Domestic (Land, D.O.T.)
-----------------------
Proper Shipping Name: ACETONE
Hazard Class: 3
UN/NA: UN1090
Packing Group: II
Information reported for product/size: 188L
International (Water, I.M.O.)
-----------------------------
Proper Shipping Name: ACETONE
Hazard Class: 3
UN/NA: UN1090
Packing Group: II
Information reported for product/size: 188L
15. Regulatory Information
--------\Chemical Inventory Status - Part 1\---------------------------------
Ingredient TSCA EC Japan Australia
----------------------------------------------- ---- --- ----- ---------
Acetone (67-64-1) Yes Yes Yes
Yes
--------\Chemical Inventory Status - Part 2\---------------------------------
--Canada--
Ingredient Korea DSL NDSL Phil.
----------------------------------------------- ----- --- ---- -----
Acetone (67-64-1) Yes Yes No Yes
--------\Federal, State & International Regulations - Part 1\----------------
-SARA 302- ------SARA 313------
Ingredient RQ TPQ List Chemical Catg.
----------------------------------------- --- ----- ---- --------------
Acetone (67-64-1) No No Yes No
--------\Federal, State & International Regulations - Part 2\----------------
-RCRA- -TSCA-
Ingredient CERCLA 261.33 8(d)
----------------------------------------- ------ ------ ------
Acetone (67-64-1) 5000 U002
No
Chemical Weapons Convention: No TSCA 12(b): No CDTA: Yes
SARA 311/312: Acute: Yes Chronic: No Fire: Yes Pressure: No
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ACETONE
Reactivity: No (Pure / Liquid)
Australian Hazchem Code: 2[Y]E
Poison Schedule: None allocated.
WHMIS:
This MSDS has been prepared according to the hazard criteria of the Controlled Products Regulations (CPR) and the
MSDS contains all of the information required by the CPR.
16. Other Information
NFPA Ratings: Health: 1 Flammability: 3 Reactivity: 0
Label Hazard Warning:
DANGER! EXTREMELY FLAMMABLE LIQUID AND VAPOR. VAPOR MAY CAUSE FLASH FIRE.
HARMFUL IF SWALLOWED OR INHALED. CAUSES IRRITATION TO SKIN, EYES AND RESPIRATORY
TRACT. AFFECTS CENTRAL NERVOUS SYSTEM.
Label Precautions:
Keep away from heat, sparks and flame.
Keep container closed.
Use only with adequate ventilation.
Wash thoroughly after handling.
Avoid breathing vapor.
Avoid contact with eyes, skin and clothing.
Label First Aid:
Aspiration hazard. If swallowed, vomiting may occur spontaneously, but DO NOT INDUCE. If vomiting occurs, keep
head below hips to prevent aspiration into lungs. Never give anything by mouth to an unconscious person. Call a
physician immediately. If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is
difficult, give oxygen. In case of contact, immediately flush eyes or skin with plenty of water for at least 15 minutes.
Remove contaminated clothing and shoes. Wash clothing before reuse. In all cases, get medical attention.
Product Use:
Laboratory Reagent.
Revision Information:
No Changes.
Disclaimer:
************************************************************************************************
Mallinckrodt Baker, Inc. provides the information contained herein in good faith but makes no representation
as to its comprehensiveness or accuracy. This document is intended only as a guide to the appropriate
precautionary handling of the material by a properly trained person using this product. Individuals receiving
the information must exercise their independent judgment in determining its appropriateness for a particular
purpose. MALLINCKRODT BAKER, INC. MAKES NO REPRESENTATIONS OR WARRANTIES,
EITHER EXPRESS OR IMPLIED, INCLUDING WITHOUT LIMITATION ANY WARRANTIES OF
MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE WITH RESPECT TO THE
INFORMATION SET FORTH HEREIN OR THE PRODUCT TO WHICH THE INFORMATION REFERS.
ACCORDINGLY, MALLINCKRODT BAKER, INC. WILL NOT BE RESPONSIBLE FOR DAMAGES
RESULTING FROM USE OF OR RELIANCE UPON THIS INFORMATION.
************************************************************************************************
Prepared by: Environmental Health & Safety
Phone Number: (314) 654-1600 (U.S.A.)
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